Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L38; homologous to mammalian ribosomal protein L38, no bacterial homolog

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0.05 0 0.08 0.06 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0.06 0.08 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.0 0.96 0.95 0.99 0.91 0.91 0.69 0.64 0.65 0.64 0.59 0.96 0.98 0.99 0.95 0.97 0.99 0.97 0.92 0.91 0.93 0.9 0.9
Endoplasmic Reticulum 0 0 0 0 0.09 0.05 0.21 0.16 0.2 0.16 0.17 0.06 0 0 0.1 0 0.07 0 0 0 0 0 0.06
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0.08 0.22 0.14 0.27 0.26 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 2 0 0 9 35 17 33 15 21 0 0 0 0 0 0 0 0 0 0 0 0
Bud 2 0 4 0 0 1 0 1 0 1 0 0 0 0 0 0 0 1 0 1 1 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 3 1 1 1 7 10 23 24 34 14 22 1 1 2 2 0 0 0 0 1 0 0 0
Cytoplasm 252 134 276 232 338 376 488 244 271 172 211 67 132 137 56 68 73 241 122 284 41 88 92
Endoplasmic Reticulum 1 6 9 0 34 20 149 62 83 43 60 4 4 2 6 1 5 1 3 13 0 2 5
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 2 1 0 1 4 22 18 8 4 16 0 0 0 2 0 0 0 0 0 0 0 0
Mitochondria 0 0 4 4 2 18 54 84 57 74 92 0 0 0 2 1 0 0 0 1 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0
Nuclear Periphery 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 2 0 1 0 13 12 10 2 5 0 0 0 1 3 0 1 1 2 0 1 1
Unique Cell Count 253 139 291 235 372 415 706 384 420 270 358 70 135 138 59 70 74 250 133 311 45 98 103
Labelled Cell Count 258 143 299 237 384 438 786 462 499 326 427 72 137 141 69 73 78 250 133 311 45 98 103


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 59.8 69.2 38.3 47.3 38.5 28.4 23.0 21.3 21.2 20.2 20.8 58.3 55.6 54.7 85.0 59.3 84.4 60.1 67.4 64.1
Std Deviation (1e-4) 13.3 15.6 10.1 10.0 8.6 5.1 5.1 5.1 4.7 4.3 4.8 14.1 11.0 8.8 32.3 24.2 29.2 12.6 16.8 16.7
Intensity Change (Log2) 0.31 0.01 -0.43 -0.74 -0.85 -0.86 -0.92 -0.88 0.61 0.54 0.51 1.15 0.63 1.14 0.65 0.82 0.74


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 3.2 2.9 4.3 3.4 3.5 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 2.7 4.0 4.7 3.6 4.0 0 0 0 0 0 0
Cytoplasm 2.4 -1.9 -2.1 -8.7 -9.6 -9.4 -9.2 -10.5 0.3 1.4 2.3 0 0.8 1.4
Endoplasmic Reticulum 0 3.1 1.1 7.1 5.5 6.5 5.2 5.6 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 2.7 3.4 0 0 3.3 0 0 0 0 0 0
Mitochondria 0 0 2.2 3.8 7.8 5.7 8.9 8.7 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.2 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 60.082 67.4418 65.4626 56.5814 66.3324 62.1582 57.3077 71.6949 61.9054 59.1343 57.1316 65.9236 60.875 75.6579 66.9925 70.5389 63.096 65.715
Actin 0.0013 0.0008 0.0016 0.005 0.0005 0.0023 0.0024 0.0003 0.0117 0.0187 0.0004 0.0027 0.0008 0.0003 0.0013 0.0003 0.001 0.0085
Bud 0.0009 0.0005 0.0011 0.0009 0.0004 0.0014 0.0016 0.0003 0.0016 0.0011 0.0004 0.0021 0.0014 0.0005 0.0009 0.0028 0.0015 0.0014
Bud Neck 0.0008 0.0006 0.0008 0.0023 0.0007 0.0017 0.0011 0.0004 0.0007 0.0018 0.0005 0.0016 0.0006 0.0003 0.0004 0.0006 0.0008 0.0013
Bud Periphery 0.0015 0.0005 0.0017 0.0007 0.0002 0.0018 0.0012 0.0002 0.0012 0.0009 0.0002 0.0027 0.0017 0.0003 0.0009 0.0031 0.0014 0.0022
Bud Site 0.0005 0.0003 0.0005 0.0007 0.0001 0.0005 0.0077 0.0003 0.0033 0.0043 0.0003 0.0002 0.0004 0.0003 0.0003 0.0001 0.0002 0.0004
Cell Periphery 0.0144 0.0091 0.0101 0.003 0.0034 0.0025 0.0033 0.0039 0.004 0.0005 0.0001 0.0024 0.003 0.0013 0.0021 0.0009 0.0011 0.0023
Cytoplasm 0.7362 0.894 0.8319 0.7655 0.8962 0.7967 0.7967 0.9434 0.8131 0.7708 0.8497 0.8316 0.7881 0.9719 0.8872 0.8443 0.8283 0.8066
Cytoplasmic Foci 0.0021 0.0019 0.003 0.0058 0.0065 0.0052 0.0093 0.0014 0.0184 0.0255 0.0308 0.0077 0.0111 0.0015 0.0043 0.004 0.0105 0.0107
Eisosomes 0.0001 0 0.0001 0.0001 0 0 0.0001 0 0.0005 0.0003 0 0 0.0001 0 0 0 0.0002 0.0001
Endoplasmic Reticulum 0.0931 0.0414 0.0463 0.0369 0.0149 0.0969 0.0421 0.0244 0.0379 0.0042 0.003 0.0305 0.0567 0.0064 0.0196 0.0064 0.0047 0.0576
Endosome 0.0097 0.0043 0.0099 0.0146 0.0237 0.0252 0.0203 0.0025 0.0147 0.0526 0.0558 0.0331 0.0193 0.0027 0.0116 0.0261 0.0214 0.0317
Golgi 0.0029 0.0011 0.0015 0.0046 0.004 0.0069 0.0019 0.0004 0.0043 0.006 0.0071 0.0106 0.0025 0.0007 0.0014 0.0016 0.0022 0.011
Lipid Particles 0.001 0.0018 0.001 0.0087 0.0011 0.0008 0.0028 0.0003 0.0059 0.0055 0.0052 0.0006 0.004 0.0001 0.0008 0.0001 0.0159 0.0056
Mitochondria 0.0047 0.0022 0.0048 0.0038 0.0004 0.0048 0.007 0.0003 0.0088 0.0018 0.0106 0.0119 0.0171 0.0005 0.0067 0.0022 0.0088 0.0075
None 0.0014 0.0002 0.0006 0.001 0.0002 0.0015 0.0036 0.0001 0.0044 0.0023 0.0003 0.0036 0.0032 0.0002 0.0032 0.0003 0.0047 0.0019
Nuclear Periphery 0.0183 0.0032 0.0073 0.004 0.0024 0.0064 0.0159 0.0015 0.0039 0.0044 0.0018 0.0047 0.011 0.0009 0.0039 0.0033 0.0072 0.0043
Nucleolus 0.0018 0.0001 0.0003 0.0007 0.0001 0.0007 0.0014 0.0001 0.0009 0.0005 0 0.0001 0.0022 0 0.0006 0 0.005 0.0005
Nucleus 0.0064 0.0015 0.0026 0.0028 0.0012 0.0031 0.006 0.0009 0.0029 0.0023 0.001 0.0019 0.0045 0.0006 0.0035 0.0015 0.0045 0.0033
Peroxisomes 0 0 0.0001 0.0068 0 0.0001 0.0004 0 0.0013 0.0016 0.0014 0.0001 0.0004 0 0.0004 0 0.003 0.0063
Punctate Nuclear 0.0005 0 0.0001 0.0016 0 0.0061 0.0015 0 0.0014 0.0018 0.0003 0.0001 0.0014 0 0.004 0 0.0189 0.0003
Vacuole 0.0877 0.0333 0.0638 0.1135 0.038 0.0263 0.0602 0.0176 0.0464 0.073 0.0205 0.0345 0.0534 0.0101 0.0388 0.0703 0.0379 0.0229
Vacuole Periphery 0.0148 0.0028 0.011 0.017 0.0061 0.009 0.0137 0.0018 0.0128 0.0202 0.0105 0.0172 0.0172 0.0016 0.0083 0.0321 0.0209 0.0136

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2274.3168 2251.6013 2294.6275 2578.4556 2734.4611 1810.0705 2071.446 2130.147 2091.1497 2074.9688
Translational Efficiency 2.0803 2.0747 2.2264 1.5774 2.0644 2.9046 2.0391 1.849 2.1644 2.4947

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L38; homologous to mammalian ribosomal protein L38, no bacterial homolog
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rpl38

Rpl38


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl38-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available