Standard name
Description ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.98 1.0 0.96 0.96 0.95 0.97 0.85 0.89 0.85 0.85 1.0 0.99 0.99 0.96 0.89 0.85 0.91 0.89 0.83 0.92 0.91 0.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0.18 0.1 0.26 0.13 0 0 0 0 0 0.07 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 1 0 1 0 0
Bud 0 0 0 0 0 2 0 4 6 3 3 0 0 0 0 0 0 0 3 0 1 6 1
Bud Neck 1 0 2 0 3 1 1 0 5 2 10 0 0 0 0 0 0 0 1 1 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Cell Periphery 2 1 2 0 1 1 0 1 1 3 0 0 0 1 0 2 0 0 0 1 0 1 0
Cytoplasm 174 309 97 115 151 206 238 126 168 213 237 250 226 242 25 66 35 167 289 94 126 204 180
Endoplasmic Reticulum 1 2 0 0 1 0 0 0 1 1 3 0 1 1 2 2 1 0 0 1 0 0 2
Endosome 0 1 0 0 0 3 0 1 0 1 0 0 1 0 1 2 1 1 5 0 0 0 0
Golgi 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 1 2 1 2 0 0 0 0
Mitochondria 4 0 0 1 0 3 1 26 19 65 37 0 1 0 1 1 3 4 8 4 1 2 4
Nucleus 0 0 1 1 3 2 0 1 1 2 3 0 0 0 1 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 1 2 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 1 0 1 0 0 1 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 1 1 4 2 2 1 8 0 0 0 0 2 1 0 1 0 0 1 0
Vac/Vac Membrane 0 2 0 1 1 6 5 4 4 6 8 0 0 0 0 0 2 2 5 3 1 1 1
Unique Cell Count 179 314 97 120 157 217 245 148 188 252 280 251 228 244 26 74 41 184 326 113 138 225 200
Labelled Cell Count 182 316 103 120 163 226 251 168 209 298 312 251 229 245 30 78 45 184 326 113 138 225 200


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.5 4.6 5.1 5.2 6.2 5.0 4.9 4.3 4.4 3.9 4.2 5.2 5.2 5.4 6.2 6.0 5.8 4.9 5.0 5.0
Std Deviation (1e-4) 0.5 1.2 1.2 3.2 2.7 2.4 2.1 1.7 1.7 1.9 2.2 1.6 1.0 2.1 2.4 1.9 2.8 1.5 1.9 1.3
Intensity Change (Log2) 0.02 0.28 -0.05 -0.07 -0.26 -0.24 -0.41 -0.3 0.02 0.0 0.07 0.26 0.21 0.18 -0.08 -0.03 -0.05


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin
Bud
Bud Neck
Bud Site
Cell Periphery
Cyto
Endoplasmic Reticulum
Endosome
Golgi
Mitochondria
Nuclear Periphery
Nuc
Nucleolus
Peroxisomes
SpindlePole
Vac
Cortical Patches
Cytoplasm
Nucleus
Vacuole


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kar2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available