Standard name
Description Regulatory subunit of type 1 protein phosphatase Glc7p; involved in negative regulation of glucose-repressible genes; involved in regulation of the nucleocytoplasmic shuttling of Hxk2p; REG1 has a paralog, REG2, that arose from the whole genome duplication

Micrographs

Sub-cellular Localization

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0.08 0 0 0 0 0 0 0
Cytoplasm 0.91 0.97 0.98 0.98 0.96 0.96 0.93 0.91 0.90 0.83 0.86 0.98 0.99 0.99 0.94 0.90 0.98 0.86 0.92 0.91 0.91 0.88 0.86
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0.05 0.05
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.07 0.11 0.17 0.17 0.28 0.22 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.10 0 0 0 0.05 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 2 1 3 0 1 0 0 1 1 0 0 0 0 0 0 0 3 2
Bud 0 0 5 3 2 5 5 9 8 6 2 4 4 14 0 0 0 1 1 0 0 1 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 3 3 2 2 6 10 21 8 10 14 14 3 6 15 6 7 4 0 0 0 0 0 0
Cytoplasm 231 320 414 320 355 438 520 459 243 255 316 234 484 511 167 78 101 229 307 402 253 290 354
Endoplasmic Reticulum 5 5 8 1 12 5 9 4 2 9 10 0 2 1 5 3 9 2 1 4 8 17 21
Endosome 7 2 0 1 1 2 0 1 0 0 0 1 1 0 0 0 0 9 3 2 2 3 8
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 1 0 0 1 3
Mitochondria 1 0 1 12 11 34 62 88 45 86 82 1 0 2 3 1 2 2 1 4 2 2 1
Nucleus 3 1 2 1 1 0 1 0 0 1 2 0 0 1 2 1 1 1 1 0 0 0 0
Nuclear Periphery 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 2
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 2
Vac/Vac Membrane 8 5 3 0 4 1 6 4 2 1 4 1 0 1 4 9 3 8 9 21 7 3 6
Unique Cell Count 253 329 424 326 370 456 561 506 269 309 366 238 487 516 177 87 103 268 333 442 279 331 412
Labelled Cell Count 262 336 435 340 392 497 625 576 310 373 430 244 498 546 189 99 120 268 333 442 279 331 412

Yeast GFP Assignment

(Huh et al. Nature 2003 425:686 )

Cytoplasm

Protein Abundance

Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.5 8.7 6.9 6.5 7.1 6.4 6.3 6.1 6.0 5.8 5.7 9.0 9.1 8.3 10.7 12.0 11.6 9.3 10.0 10.0
Std Deviation (1e-4) 1.7 1.2 0.8 0.8 0.9 1.0 0.8 1.0 1.0 1.0 1.1 1.3 1.2 1.0 1.8 1.7 2.0 1.3 1.9 1.8
Intensity Change (Log2) -0.1 0.0 -0.1 -0.1 -0.2 -0.2 -0.3 -0.3 0.4 0.4 0.3 0.6 0.8 0.7 0.4 0.5 0.5

Localization Change

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0.7 1.7 0 0 0 0 1.7 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 2.2 3.4 0 0 3.7 3.3 0 0 2.8 0 0 0
Cytoplasm 2.6 3.8 1.4 2.0 -0.5 -0.2 0.9 3.0 -1.7 -1.5 -2.4 6.1 3.2 3.0
Endoplasmic Reticulum 0 1.2 -1.0 -0.3 -1.5 0 0.9 0.8 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.6 3.2 5.5 6.9 8.9 8.5 11.4 10.1 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0