Standard name
Human Ortholog
Description One of four subunits of the ESCRT-III complex; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes; ESCRT-III stands for endosomal sorting complex required for transport III
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – – 0.1 – – 0 0 0 – 0.09 0.05 0 – – – 0 – – – 0.1 0.06 – 0 0
Bud – – 0.14 – – 0 0 0 – 0 0 0 – – – 0 – – – 0 0 – 0 0
Bud Neck – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – 0.06 0 – 0 0
Bud Site – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – – – – – –
Cell Periphery – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – 0 0 – 0 0
Cytoplasm – – 0 – – 0.16 0.06 0.12 – 0 0 0.12 – – – 0.12 – – – 0 0 – 0 0
Endoplasmic Reticulum – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – 0 0 – 0 0
Endosome – – 0.1 – – 0.05 0.06 0.16 – 0.3 0.08 0 – – – 0.12 – – – 0.45 0.47 – 0.5 0.98
Golgi – – 0.05 – – 0 0 0 – 0.09 0 0 – – – 0 – – – 0.05 0.12 – 0 0
Mitochondria – – 0.33 – – 0.68 0.72 0.68 – 0.57 0.87 0.76 – – – 0.06 – – – 0.06 0 – 0 0
Nucleus – – 0 – – 0 0 0 – 0 0 0 – – – 0.06 – – – 0 0 – 0 0
Nuclear Periphery – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – 0 0 – 0 0
Nucleolus – – 0.1 – – 0.32 0.28 0.24 – 0.17 0.16 0.06 – – – 0.69 – – – 0 0 – 0 0
Peroxisomes – – 0.38 – – 0 0.06 0 – 0.13 0.08 0.06 – – – 0 – – – 0.11 0.24 – 0 0
SpindlePole – – 0.33 – – 0.05 0.06 0 – 0.09 0 0.12 – – – 0.25 – – – 0.07 0 – 0 0
Vac/Vac Membrane – – 0 – – 0.05 0 0 – 0 0.08 0 – – – 0 – – – 0 0 – 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – – 2 – – 0 1 0 – 2 2 0 – – – 0 – – – 1 2 – 0 0
Bud – – 3 – – 0 0 0 – 1 0 0 – – – 0 – – – 0 1 – 0 0
Bud Neck – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – 1 0 – 0 0
Bud Site – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – – – – – –
Cell Periphery – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – 0 0 – 0 0
Cytoplasm – – 0 – – 3 2 3 – 0 1 2 – – – 2 – – – 0 0 – 0 0
Endoplasmic Reticulum – – 0 – – 0 0 0 – 0 0 0 – – – 0 – – – 0 0 – 0 0
Endosome – – 2 – – 1 2 4 – 7 3 0 – – – 2 – – – 8 23 – 1 2
Golgi – – 1 – – 0 0 1 – 2 1 0 – – – 0 – – – 0 5 – 0 0
Mitochondria – – 7 – – 13 26 17 – 13 33 13 – – – 1 – – – 1 1 – 0 0
Nucleus – – 0 – – 0 1 0 – 0 0 0 – – – 1 – – – 0 0 – 0 0
Nuclear Periphery – – 0 – – 0 1 0 – 0 1 0 – – – 0 – – – 0 0 – 0 0
Nucleolus – – 2 – – 6 10 6 – 4 6 1 – – – 11 – – – 0 0 – 0 0
Peroxisomes – – 8 – – 0 2 1 – 3 3 1 – – – 0 – – – 2 12 – 0 0
SpindlePole – – 7 – – 1 2 1 – 2 1 2 – – – 4 – – – 1 1 – 0 0
Vac/Vac Membrane – – 0 – – 1 1 0 – 0 3 0 – – – 0 – – – 0 0 – 0 0
Unique Cell Count 21 19 36 25 23 38 17 16 19 51 2 3
Labelled Cell Count 32 25 48 33 34 54 19 21 19 51 2 3


Endosome

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – – 9.8 – – 10.7 10.6 11.1 – 12.8 12.4 11.6 – – – 15.9 – – – – –
Std Deviation (1e-4) – – 5.0 – – 2.7 2.8 3.2 – 3.6 3.5 3.5 – – – 5.5 – – – – –
Intensity Change (Log2) – – – – – 0.13 0.12 0.19 – 0.39 0.35 0.25 – – – 0.71 – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches – – 0 0 0 – 0 0 0 – – – 0 – –
Bud – – 0 0 0 – 0 0 0 – – – 0 – –
Bud Neck – – 0 0 0 – 0 0 0 – – – 0 – –
Bud Site – – 0 0 0 – 0 0 0 – – – 0 – –
Cell Periphery – – 0 0 0 – 0 0 0 – – – 0 – –
Cytoplasm – – 0 0 0 – 0 0 0 – – – 0 – –
Endoplasmic Reticulum – – 0 0 0 – 0 0 0 – – – 0 – –
Endosome – – 0 0 0 – 0 0 0 – – – 0 – –
Golgi – – 0 0 0 – 0 0 0 – – – 0 – –
Mitochondria – – 2.2 2.9 2.3 – 1.5 4.2 2.6 – – – 0 – –
Nucleus – – 0 0 0 – 0 0 0 – – – 0 – –
Nuclear Periphery – – 0 0 0 – 0 0 0 – – – 0 – –
Nucleolus – – 0 0 0 – 0 0 0 – – – 3.7 – –
Peroxisomes – – 0 0 0 – -1.9 0 0 – – – 0 – –
SpindlePole – – 0 0 0 – 0 0 0 – – – 0 – –
Vacuole – – 0 0 0 – 0 0 0 – – – 0 – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin – – – – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – – – – –
Bud Periphery – – – – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – – – – –
Cytoplasmic Foci – – – – – – – – – – – – – – – – – –
Eisosomes – – – – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – – – – –
Lipid Particles – – – – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – – – – –
None – – – – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – – – – –
Punctate Nuclear – – – – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – – – – –
Vacuole Periphery – – – – – – – – – – – – – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.683 24.5571 18.2224 31.8097 28.6914 32.0313 30.0025 38.6373 39.6077 29.0473
Translational Efficiency 8.4673 3.1888 4.3129 2.7394 2.941 2.627 2.7394 2.1693 2.5197 2.9036

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization –
Gene Expression ✘
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Snf7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available