Standard name
Human Ortholog
Description Subunit (61/68 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A; overexpression of the human ortholog, TAF12, an oncogene involved in the formation of choroid plexus carcinomas, results in dosage chromosomal instability (dCIN) in a human cell line similar to the dCIN observed in yeast overexpressors
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.07 0.2 0.15 0.14 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.06 0.06 0.11 0.06 0.12 0.16 0.27 0.18 0.18 0.27 0.19 0.27 0 0 0 0.05 0 0.07 0 0 0 0 0 0
Nucleus 0.79 0.85 0.8 0.79 0.73 0.64 0.57 0.58 0.52 0.56 0.56 0.49 0.76 0.75 0.73 0.59 0.61 0.6 0.63 0.8 0.71 0.49 0.41 0.42
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.54 0.33 0.41 0.48 0.39 0.54 0.51 0.49 0.58 0.57 0.59 0.55 0.54 0.44 0.45 0.22 0.23 0.29 0.27 0.12 0.21 0.41 0.4 0.43
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 1 2 0 6 2 2 3 4 4 0 1 0 0 0 0 2 3 2 0 0 1
Bud Neck 0 0 0 0 1 1 1 5 0 4 1 3 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 1 3 1 3 6 3 18 10 10 20 7 6 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3 5 6 5 4 7 7 13 9 0 2 4 0 10 8 41 15 12 1 0 0 1 0 0
Endoplasmic Reticulum 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 8 3 1 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 3 4 0 2 1 0 3 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 3 2
Mitochondria 4 17 29 12 35 58 152 96 57 105 44 67 2 1 1 10 3 6 0 2 1 1 3 1
Nucleus 56 231 216 170 210 234 316 305 166 216 131 123 61 120 85 120 61 51 47 239 198 48 49 56
Nuclear Periphery 0 1 0 5 3 4 13 7 5 6 1 5 0 1 0 0 0 0 0 0 1 0 0 0
Nucleolus 38 90 111 103 113 197 287 257 184 217 140 138 43 70 53 45 23 25 20 35 58 40 48 58
Peroxisomes 1 0 0 1 0 0 1 1 0 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0
SpindlePole 1 1 2 0 3 1 2 4 2 0 0 1 0 1 4 2 3 1 0 3 1 2 0 2
Vac/Vac Membrane 0 2 0 0 1 2 1 4 0 1 0 1 0 2 1 6 4 4 3 8 11 2 4 7
Unique Cell Count 71 272 270 216 287 366 558 529 319 383 236 249 80 159 117 204 100 85 76 301 281 99 120 136
Labelled Cell Count 104 350 366 300 378 507 804 704 435 572 330 352 106 207 155 238 116 104 76 301 281 99 120 136


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.7 8.8 7.5 7.3 7.1 6.6 5.8 6.6 6.8 6.2 6.4 6.6 8.7 9.3 9.1 12.0 13.0 13.0 7.7 7.6 8.9
Std Deviation (1e-4) 1.9 2.2 2.5 1.9 2.3 1.9 2.0 2.4 1.9 2.0 1.8 2.2 1.4 3.0 2.9 3.5 3.8 4.3 1.8 1.6 2.0
Intensity Change (Log2) – – – -0.04 -0.09 -0.18 -0.37 -0.18 -0.14 -0.28 -0.22 -0.19 0.21 0.31 0.27 0.67 0.79 0.79 0.03 0.02 0.25


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 2.6 0 2.5 3.5 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 -0.3 0 0.2 0.5 0 0 0 0 2.1 0 6.4 4.7 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -2.0 0.5 1.9 5.4 2.7 2.4 5.2 2.5 4.7 -2.3 -4.0 -3.3 -2.3 -2.4 -1.0
Nucleus -0.4 -1.9 -4.4 -6.6 -6.3 -7.1 -6.3 -5.9 -7.3 -0.7 -1.1 -1.6 -5.0 -3.7 -3.7
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1.5 -0.4 3.2 2.8 2.0 4.0 3.9 4.1 3.3 2.0 0.6 0.8 -4.4 -3.2 -1.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin – – – – – – 0.0175 0.0001 0.0025 0 0 0 0.0432 0.001 0.0533 0.001 0.0001 0.001
Bud – – – – – – 0.0005 0 0.0005 0 0.0001 0 0.0006 0.0001 0.0003 0 0 0.0007
Bud Neck – – – – – – 0.0003 0.0001 0.0002 0 0.0003 0.0002 0.0005 0.0001 0.0003 0.0001 0.0002 0.0011
Bud Periphery – – – – – – 0.0004 0 0.0005 0 0.0002 0 0.0011 0.0001 0.0003 0 0.0001 0.0017
Bud Site – – – – – – 0.0025 0.0003 0.0023 0 0.0001 0 0.0011 0.0004 0.0009 0.0001 0.0001 0.0006
Cell Periphery – – – – – – 0.0001 0 0.0001 0 0.0001 0 0.0002 0 0.0001 0 0.0001 0.0005
Cytoplasm – – – – – – 0.0127 0.0001 0.002 0 0 0 0.0072 0.0226 0.0034 0.0001 0 0.0004
Cytoplasmic Foci – – – – – – 0.0366 0.0008 0.0112 0 0 0 0.0413 0.0059 0.0115 0.0044 0.0024 0.0008
Eisosomes – – – – – – 0.0001 0 0 0 0 0 0.0005 0 0.0003 0 0 0
Endoplasmic Reticulum – – – – – – 0.0088 0 0.0003 0 0 0 0.0176 0.0091 0.0039 0.0001 0 0.0003
Endosome – – – – – – 0.0674 0.0001 0.007 0 0.0001 0 0.0592 0.033 0.0258 0.0062 0.0011 0.001
Golgi – – – – – – 0.0186 0.0001 0.0049 0 0 0 0.0155 0.0054 0.0177 0.0041 0.0017 0.0003
Lipid Particles – – – – – – 0.0052 0.0003 0.004 0 0.0001 0 0.0708 0.0005 0.0069 0.0357 0.0646 0.0012
Mitochondria – – – – – – 0.0041 0.0002 0.0018 0 0.0009 0.0001 0.0125 0.0013 0.0123 0.0007 0.0091 0.0088
None – – – – – – 0.0072 0.0001 0.001 0 0.0001 0 0.0357 0.0009 0.003 0.0001 0 0.0002
Nuclear Periphery – – – – – – 0.0146 0.0007 0.0093 0 0.0008 0.0001 0.0708 0.0015 0.0018 0.0009 0.0009 0.0015
Nucleolus – – – – – – 0.0288 0.0265 0.0207 0.028 0.1827 0.1519 0.061 0.0828 0.0203 0.0445 0.3142 0.1573
Nucleus – – – – – – 0.6481 0.8762 0.8832 0.9718 0.8126 0.8474 0.4874 0.8322 0.8259 0.8925 0.5987 0.8161
Peroxisomes – – – – – – 0.004 0.0001 0.0041 0 0 0 0.0116 0.0001 0.0073 0.0076 0.0011 0.0003
Punctate Nuclear – – – – – – 0.1197 0.0938 0.0437 0.0001 0.0015 0.0002 0.0549 0.0015 0.0036 0.0019 0.0028 0.0032
Vacuole – – – – – – 0.0012 0.0002 0.0004 0 0.0003 0 0.0025 0.0009 0.0005 0.0001 0.0008 0.0023
Vacuole Periphery – – – – – – 0.0015 0.0001 0.0003 0 0.0002 0 0.005 0.0006 0.0005 0.0001 0.0018 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 44.9535 33.4881 25.3014 39.0711 33.9991 34.7176 39.5544 43.0053 33.1846 42.476
Translational Efficiency 1.4413 1.883 1.9895 1.1403 1.7047 1.9765 1.2545 1.1391 1.4882 1.1993

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Taf12-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available