Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L24A; not essential for translation but may be required for normal translation rate; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24A has a paralog, RPL24B, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.0 1.0 0.97 0.98 0.97 0.96 0.88 0.84 0.79 0.8 0.72 0.69 0.99 0.99 0.98 0.99 0.99 0.99 0.97 0.97 0.94 0.92 0.9 0.92
Endoplasmic Reticulum 0 0 0 0 0 0 0.11 0.11 0.13 0.15 0.12 0.17 0 0 0 0.05 0.08 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0.11 0.12 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 4 4 3 10 8 7 0 0 1 0 0 0 0 0 0 0 0 0
Bud 1 0 1 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 2 0 0 0 2 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 0 0 1 3 2 5 8 7 5 6 2 0 1 3 2 0 0 0 0 0 0 0
Cytoplasm 537 117 107 107 207 130 149 156 158 192 79 125 212 227 270 175 150 190 504 102 93 99 209 215
Endoplasmic Reticulum 1 0 1 0 5 6 18 21 26 35 13 31 2 2 3 9 12 14 1 0 2 0 7 7
Endosome 0 0 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 2 2 4 3 4 1 0 0 1 1 0 0 0 0 0 0 0 0
Mitochondria 0 0 1 1 0 2 1 4 7 5 12 22 0 1 0 1 0 3 0 0 0 0 0 0
Nucleus 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 1 1 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 1 1 1 1 0 1 0 0 1 0 0 3 1 0 0 3 5 2
Unique Cell Count 538 117 110 109 213 136 169 186 199 241 110 181 214 230 275 177 151 191 518 106 100 108 232 234
Labelled Cell Count 540 117 113 112 213 141 177 195 207 254 121 195 216 231 277 189 164 210 518 106 100 108 232 234


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 166.5 206.7 107.9 107.9 97.4 67.1 56.5 52.2 46.4 45.0 38.7 38.6 166.8 156.8 149.9 244.6 239.5 223.6 173.5 184.0 198.6
Std Deviation (1e-4) 30.6 44.0 32.1 32.1 20.7 16.4 14.7 15.2 11.8 10.8 11.0 9.5 34.8 42.9 30.6 89.8 87.1 77.8 39.9 53.2 49.2
Intensity Change (Log2) – – – 0.0 -0.15 -0.68 -0.93 -1.05 -1.22 -1.26 -1.48 -1.48 0.63 0.54 0.47 1.18 1.15 1.05 0.69 0.77 0.88


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.4 0 -0.7 -2.7 -3.5 -4.3 -4.3 -5.2 -5.8 1.2 0.9 0.6 1.0 1.3 1.6
Endoplasmic Reticulum 0 0 0 3.2 3.3 3.6 3.9 3.3 4.3 0 0 0 0 2.6 2.5
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 3.1 3.4 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 123.6278 178.2893 168.0322 154.4818 126.3017 167.6341 143.8715 191.7171 167.6301 152.431 121.3609 135.8059 169.2112 203.8352 190.2969 163.7948 165.1265 183.2357
Actin 0.0138 0.0003 0.0064 0.0015 0.0545 0.0021 0.005 0.0036 0.0042 0.0011 0.001 0.0036 0.0016 0.0004 0.0021 0.002 0.002 0.0007
Bud 0.0066 0.0015 0.0071 0.0051 0.002 0.0038 0.0041 0.002 0.0039 0.004 0.0022 0.009 0.0025 0.0009 0.0029 0.0037 0.0017 0.0036
Bud Neck 0.0011 0.0005 0.0012 0.0027 0.0015 0.0008 0.0008 0.0005 0.0009 0.0008 0.0017 0.0034 0.0006 0.0004 0.0008 0.0014 0.0008 0.0026
Bud Periphery 0.0084 0.0006 0.004 0.0018 0.0008 0.0016 0.0035 0.0028 0.0034 0.0026 0.005 0.0069 0.0027 0.0006 0.0022 0.0041 0.0008 0.0015
Bud Site 0.0047 0.0009 0.0054 0.0014 0.0033 0.0003 0.0025 0.0018 0.0022 0.0018 0.0003 0.0091 0.0011 0.0007 0.0017 0.0006 0.0071 0.0002
Cell Periphery 0.0467 0.0269 0.0276 0.0289 0.0029 0.0014 0.0427 0.016 0.0164 0.0535 0.0059 0.0055 0.0296 0.0111 0.0207 0.0326 0.0036 0.0017
Cytoplasm 0.4932 0.8637 0.7123 0.5979 0.5866 0.7253 0.606 0.8968 0.7439 0.5409 0.6878 0.5608 0.6488 0.8985 0.7771 0.5578 0.7543 0.9105
Cytoplasmic Foci 0.0208 0.0012 0.0128 0.0043 0.0377 0.0061 0.0035 0.0013 0.0073 0.0047 0.0023 0.0992 0.0087 0.0011 0.0061 0.0043 0.0151 0.0034
Eisosomes 0.0027 0 0.0012 0.0001 0.0004 0 0.0036 0 0.0005 0.0031 0 0.0003 0.0003 0 0.0003 0.0001 0.0004 0
Endoplasmic Reticulum 0.0318 0.0037 0.0084 0.0069 0.0017 0.0041 0.0387 0.0049 0.0075 0.0024 0.0188 0.0086 0.0534 0.0108 0.011 0.0126 0.0064 0.0094
Endosome 0.0216 0.0024 0.0084 0.0228 0.0354 0.0152 0.0103 0.002 0.0073 0.0056 0.0303 0.0428 0.0114 0.0027 0.0094 0.0168 0.0484 0.0113
Golgi 0.0065 0.0002 0.0041 0.0011 0.0205 0.0023 0.0022 0.0012 0.0016 0.0013 0.0012 0.0099 0.0021 0.0005 0.0009 0.0031 0.0082 0.0008
Lipid Particles 0.0109 0.0011 0.008 0.003 0.0341 0.0002 0.0038 0.0008 0.0031 0.0076 0.0013 0.0133 0.004 0.0007 0.0019 0.0036 0.0061 0.0002
Mitochondria 0.0508 0.0007 0.0152 0.003 0.0154 0.0132 0.0197 0.0014 0.0162 0.007 0.0155 0.0239 0.0072 0.0008 0.0071 0.0185 0.0484 0.0013
None 0.0178 0.0004 0.0048 0.0113 0.0015 0.0018 0.0033 0.0003 0.0025 0.003 0.0026 0.006 0.0041 0.0002 0.0023 0.0055 0.0127 0.0002
Nuclear Periphery 0.0552 0.0063 0.0194 0.0302 0.006 0.0359 0.058 0.0033 0.011 0.0126 0.0389 0.0044 0.0457 0.0041 0.01 0.0181 0.0052 0.0039
Nucleolus 0.0081 0.0008 0.0059 0.0031 0.0021 0.0007 0.0052 0.0005 0.003 0.0095 0.0005 0.0241 0.003 0.0002 0.0039 0.0061 0.0059 0.0001
Nucleus 0.0249 0.006 0.0156 0.0201 0.0083 0.0223 0.0162 0.0026 0.0081 0.0074 0.0057 0.0113 0.0118 0.0017 0.0056 0.0102 0.0042 0.0027
Peroxisomes 0.0064 0.0001 0.0138 0.0003 0.0256 0.0004 0.0004 0.0001 0.0007 0.0005 0.0001 0.0044 0.0004 0 0.0002 0.0004 0.0008 0.0001
Punctate Nuclear 0.0048 0 0.0012 0.0003 0.0011 0.0002 0.0005 0 0.0004 0.0003 0.0001 0.0608 0.0011 0 0.0002 0.0003 0.0007 0
Vacuole 0.1092 0.0706 0.0825 0.1611 0.0854 0.0563 0.1348 0.0528 0.1323 0.2506 0.0847 0.0489 0.1263 0.0548 0.1092 0.2091 0.0487 0.0327
Vacuole Periphery 0.0539 0.0119 0.0348 0.0931 0.0733 0.1061 0.0351 0.0054 0.0237 0.0798 0.0939 0.0438 0.0335 0.0097 0.0246 0.0895 0.0183 0.0132

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2035.8755 2194.0547 2783.8503 1963.3475 2532.6114 2429.4449 1930.1841 1713.0205 2216.3119 1690.5575
Translational Efficiency 1.6778 1.597 1.3202 2.2189 1.6391 1.3327 1.4272 1.8556 1.3372 1.6929

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L24A; not essential for translation but may be required for normal translation rate; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24A has a paralog, RPL24B, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-1

Rpl24a

Rpl24a


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl24a-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available