Standard name | |
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Human Ortholog | |
Description | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation |
ensLOC | DeepLoc | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
Cortical Patches | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5 | 0 | 3 | 1 |
Bud | 0 | 0 | 0 | 1 | 0 | 0 | 4 | 2 | 4 | 1 | 5 | 6 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 3 | 2 | 2 | 2 |
Bud Neck | 0 | 0 | 11 | 4 | 15 | 5 | 8 | 18 | 0 | 8 | 5 | 8 | 0 | 1 | 0 | 1 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 3 |
Bud Site | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
Cell Periphery | 0 | 1 | 3 | 0 | 1 | 2 | 2 | 2 | 0 | 0 | 1 | 0 | 2 | 1 | 1 | 3 | 4 | 7 | 0 | 0 | 3 | 0 | 1 | 2 |
Cytoplasm | 193 | 178 | 211 | 176 | 317 | 197 | 276 | 349 | 147 | 192 | 131 | 163 | 154 | 233 | 216 | 207 | 193 | 254 | 142 | 156 | 138 | 103 | 175 | 149 |
Endoplasmic Reticulum | 0 | 1 | 2 | 1 | 2 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 1 | 3 | 1 | 18 | 13 | 20 | 2 | 0 | 1 | 0 | 1 | 3 |
Endosome | 0 | 0 | 2 | 0 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 3 | 4 | 3 | 1 | 4 | 2 | 0 | 0 | 0 |
Golgi | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 1 | 3 | 0 | 0 | 0 | 0 |
Mitochondria | 33 | 11 | 1 | 5 | 2 | 13 | 44 | 55 | 55 | 34 | 72 | 54 | 1 | 0 | 1 | 8 | 9 | 8 | 30 | 16 | 26 | 8 | 10 | 9 |
Nucleus | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 4 | 1 | 3 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
Nuclear Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Nucleolus | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SpindlePole | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 2 | 0 | 4 | 1 | 2 | 1 | 2 | 3 | 4 |
Vac/Vac Membrane | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 3 | 0 | 1 | 3 | 0 | 2 | 0 | 0 | 4 | 5 | 5 | 2 | 2 | 1 | 1 | 2 | 4 |
Unique Cell Count | 203 | 182 | 216 | 180 | 324 | 209 | 300 | 382 | 171 | 212 | 175 | 192 | 157 | 236 | 219 | 220 | 206 | 270 | 195 | 194 | 198 | 129 | 210 | 186 |
Labelled Cell Count | 226 | 191 | 230 | 188 | 340 | 224 | 342 | 441 | 208 | 243 | 219 | 234 | 162 | 242 | 221 | 247 | 233 | 308 | 195 | 194 | 198 | 129 | 210 | 186 |
Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean Cell GFP Intensity (1e-4) | 3.0 | 3.8 | 4.4 | 3.9 | 4.5 | 3.7 | 3.2 | 3.7 | 3.0 | 3.5 | 3.0 | 3.2 | 4.6 | 4.9 | 4.8 | 5.2 | 5.5 | 5.1 | 4.4 | 4.8 | 5.1 |
Std Deviation (1e-4) | 0.6 | 0.8 | 1.8 | 1.3 | 2.0 | 1.9 | 1.6 | 1.3 | 1.4 | 1.6 | 1.5 | 1.0 | 1.1 | 1.2 | 1.7 | 1.4 | 2.1 | 2.1 | 1.7 | 2.4 | 2.3 |
Intensity Change (Log2) | – | – | – | -0.15 | 0.03 | -0.26 | -0.45 | -0.23 | -0.56 | -0.32 | -0.55 | -0.43 | 0.07 | 0.18 | 0.13 | 0.26 | 0.34 | 0.24 | 0.02 | 0.15 | 0.22 |
Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
R1 | R2 | R3 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Concentration | 0.2091 | 0.1674 | 0.157 | -0.0459 | 0.0713 | 0.3474 | -0.0568 | -0.277 | -0.3214 | -0.2231 | -0.2858 | -0.3246 | -1.3539 | -1.2185 | -1.4279 | -1.2158 | -1.6109 | -1.3721 |
Actin | 0.0339 | 0.0005 | 0.0035 | 0.0194 | 0.0408 | 0.0019 | 0.0239 | 0.0057 | 0.006 | 0.0301 | 0.0224 | 0.0078 | 0.0026 | 0.0005 | 0.0024 | 0.0102 | 0.0411 | 0.0044 |
Bud | 0.001 | 0.0041 | 0.0033 | 0.0002 | 0.0097 | 0.0015 | 0.0018 | 0.0002 | 0.0003 | 0.0008 | 0.0005 | 0.0002 | 0.0004 | 0.0017 | 0.0006 | 0.0003 | 0.0008 | 0.0011 |
Bud Neck | 0.0056 | 0.0001 | 0.0013 | 0.0008 | 0.0016 | 0.0002 | 0.0008 | 0.0002 | 0.0012 | 0.0014 | 0.008 | 0.0003 | 0.0002 | 0.0001 | 0.0009 | 0.0003 | 0.0032 | 0.0002 |
Bud Periphery | 0.0025 | 0.0081 | 0.0007 | 0.0004 | 0.0023 | 0.0011 | 0.0062 | 0.0002 | 0.0004 | 0.0032 | 0.0009 | 0.0003 | 0.0011 | 0.0017 | 0.0011 | 0.0003 | 0.0008 | 0.0079 |
Bud Site | 0.0064 | 0.0068 | 0.0077 | 0.0014 | 0.0025 | 0.0001 | 0.0025 | 0.0034 | 0.0035 | 0.0021 | 0.0015 | 0.0001 | 0.0026 | 0.0048 | 0.0101 | 0.001 | 0.0012 | 0.0001 |
Cell Periphery | 0.0003 | 0.0002 | 0.0002 | 0.0001 | 0.0002 | 0.0001 | 0.0004 | 0.0002 | 0.0001 | 0.0001 | 0.0002 | 0 | 0.0011 | 0.0001 | 0.0008 | 0.0001 | 0.0001 | 0 |
Cytoplasm | 0.039 | 0.063 | 0.028 | 0.0669 | 0.04 | 0.1038 | 0.0876 | 0.0569 | 0.0381 | 0.0592 | 0.0629 | 0.1757 | 0.1333 | 0.0734 | 0.0554 | 0.0889 | 0.0212 | 0.227 |
Cytoplasmic Foci | 0.0142 | 0.0023 | 0.0058 | 0.0081 | 0.0046 | 0.0085 | 0.0324 | 0.0044 | 0.0175 | 0.014 | 0.0185 | 0.0095 | 0.0126 | 0.0027 | 0.0198 | 0.011 | 0.0589 | 0.008 |
Eisosomes | 0.0005 | 0.0001 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0003 | 0.0003 | 0.0004 | 0.0002 | 0.0002 | 0.0001 | 0.0006 | 0.0004 | 0.0004 | 0.0002 | 0.0001 | 0.0001 |
Endoplasmic Reticulum | 0.0012 | 0.0004 | 0.0009 | 0.0001 | 0.0004 | 0.0004 | 0.0027 | 0.0009 | 0.0006 | 0.001 | 0.0038 | 0.0017 | 0.0018 | 0.0005 | 0.0006 | 0.0011 | 0.0006 | 0.0009 |
Endosome | 0.0063 | 0.0008 | 0.0063 | 0.0003 | 0.0014 | 0.0029 | 0.028 | 0.0024 | 0.0076 | 0.0368 | 0.0416 | 0.0042 | 0.008 | 0.0003 | 0.0072 | 0.0257 | 0.0115 | 0.0035 |
Golgi | 0.005 | 0.0001 | 0.0034 | 0.0006 | 0.0022 | 0.0002 | 0.0109 | 0.0006 | 0.0039 | 0.0093 | 0.013 | 0.0031 | 0.0021 | 0.0001 | 0.0028 | 0.0125 | 0.012 | 0.001 |
Lipid Particles | 0.0178 | 0.0001 | 0.0051 | 0.0006 | 0.004 | 0.0005 | 0.0187 | 0.0009 | 0.0039 | 0.0053 | 0.007 | 0.0116 | 0.0046 | 0.0002 | 0.0074 | 0.0119 | 0.0024 | 0.0025 |
Mitochondria | 0.0116 | 0.0004 | 0.0042 | 0.0018 | 0.0032 | 0.0006 | 0.0307 | 0.001 | 0.0242 | 0.0054 | 0.0269 | 0.0205 | 0.0086 | 0.0003 | 0.0112 | 0.0041 | 0.003 | 0.0039 |
None | 0.8295 | 0.9107 | 0.9151 | 0.885 | 0.857 | 0.872 | 0.6839 | 0.9172 | 0.8766 | 0.8151 | 0.7621 | 0.7553 | 0.8047 | 0.9102 | 0.8676 | 0.8243 | 0.8082 | 0.7347 |
Nuclear Periphery | 0.0025 | 0.0002 | 0.0006 | 0 | 0.0007 | 0.0003 | 0.0087 | 0.0011 | 0.0012 | 0.0008 | 0.0022 | 0.0009 | 0.0023 | 0.0003 | 0.0004 | 0.0009 | 0.0006 | 0.0006 |
Nucleolus | 0.0004 | 0.0002 | 0.0003 | 0.0001 | 0.001 | 0.0001 | 0.0009 | 0.0003 | 0.0005 | 0.0003 | 0.0003 | 0.0001 | 0.0002 | 0.0002 | 0.0009 | 0.0002 | 0.0003 | 0.0001 |
Nucleus | 0.0008 | 0.0006 | 0.0011 | 0.0001 | 0.0171 | 0.0012 | 0.0052 | 0.0012 | 0.0009 | 0.0015 | 0.0007 | 0.0012 | 0.0037 | 0.0007 | 0.0012 | 0.0006 | 0.0004 | 0.0017 |
Peroxisomes | 0.017 | 0.0002 | 0.0102 | 0.0139 | 0.0043 | 0.0033 | 0.0382 | 0.0009 | 0.0098 | 0.009 | 0.0184 | 0.0056 | 0.0059 | 0.0003 | 0.0033 | 0.0039 | 0.0077 | 0.0008 |
Punctate Nuclear | 0.0033 | 0.0006 | 0.0015 | 0.0001 | 0.006 | 0.0009 | 0.0052 | 0.0016 | 0.0018 | 0.0011 | 0.0013 | 0.0011 | 0.0009 | 0.0011 | 0.0045 | 0.0013 | 0.0257 | 0.0007 |
Vacuole | 0.0006 | 0.0003 | 0.0003 | 0.0001 | 0.0004 | 0.0005 | 0.0078 | 0.0003 | 0.0013 | 0.0024 | 0.0052 | 0.0003 | 0.0019 | 0.0004 | 0.0013 | 0.001 | 0.0003 | 0.0006 |
Vacuole Periphery | 0.0004 | 0.0001 | 0.0002 | 0 | 0.0002 | 0.0001 | 0.003 | 0.0001 | 0.0003 | 0.0008 | 0.0024 | 0.0004 | 0.0008 | 0 | 0.0003 | 0.0004 | 0.0002 | 0.0002 |
R1 | R2 | |||||||||
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G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Gene Expression | – | – | – | – | – | – | – | – | – | – |
Translational Efficiency | – | – | – | – | – | – | – | – | – | – |
Dataset | Hit |
---|---|
Protein Concentration | ✘ |
Protein Localization | ✘ |
Gene Expression | – |
Translational Efficiency | – |
Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
---|---|---|---|---|
37℃ | ||||
RT |
Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
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Gene | Images |
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Gene | Images |
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