Standard name
Human Ortholog
Description Basic leucine zipper (bZIP) transcription factor

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.95 0.96 0.77 0.85 0.82 0.74 0.78 0.62 0.67 0.58 0.62 0.89 0.88 0.91 0.82 0.94 0.87 0.89 0.79 0.85 0.89 0.87 0.85
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.07 0 0.13 0.24 0.23 0.42 0.34 0.58 0.37 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0.07 0 0 0 0.05 0.05 0.08 0.05 0.07 0 0 0 0 0 0 0.05 0.12 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.06 0.06 0 0.26 0.19 0.15 0.11 0.06 0.07 0.07 0.07 0.06 0.22 0.23 0.16 0.21 0.1 0.14 0 0 0.05 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 5
Bud 0 0 0 0 0 1 2 5 4 2 8 4 0 0 0 0 0 0 0 0 0 1 3 14
Bud Neck 0 0 0 0 0 0 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 1 3 3
Bud Site 0 0 0 0 0 0 1 0 0 0 0 3 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 1 0 2 0 1 0 1 0 0 1 3 1 5 0 0 0 0 0 0
Cytoplasm 227 84 52 93 207 216 280 273 198 227 184 197 335 237 386 170 93 152 225 89 86 228 218 315
Endoplasmic Reticulum 0 2 0 0 1 0 0 0 2 2 0 2 0 1 2 9 3 2 0 0 0 0 0 3
Endosome 0 0 0 0 2 0 1 0 0 0 0 2 3 2 9 0 0 2 0 0 0 1 2 6
Golgi 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Mitochondria 1 2 0 8 6 35 92 82 133 115 183 118 0 0 0 1 0 3 1 1 0 1 2 5
Nucleus 5 0 0 8 6 5 11 16 16 26 17 22 10 4 1 8 1 7 13 13 3 9 4 0
Nuclear Periphery 0 0 0 0 0 1 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 0 0 0 1 0 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 1 1 0 0 1 0 0 0 0 0 0 1 0 0 1 1 3
Vac/Vac Membrane 15 5 2 32 47 39 41 22 22 24 21 19 84 62 67 44 10 24 5 4 4 4 2 2
Unique Cell Count 235 88 54 121 243 265 377 352 317 337 316 317 377 270 425 208 99 174 252 113 101 256 251 373
Labelled Cell Count 249 93 54 142 269 299 429 402 379 400 413 370 432 306 466 235 108 195 252 113 101 256 251 373


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.4 6.9 6.3 6.2 6.3 4.9 4.6 4.8 4.2 4.0 3.8 4.0 7.2 8.5 7.6 7.9 9.2 8.7 7.2 9.2 8.6
Std Deviation (1e-4) 0.6 0.9 1.0 1.4 1.8 1.3 1.6 1.3 1.6 0.7 1.1 0.9 0.9 4.3 2.5 1.3 2.1 1.5 3.8 7.6 4.9
Intensity Change (Log2) -0.01 0.01 -0.36 -0.44 -0.4 -0.57 -0.64 -0.73 -0.65 0.2 0.44 0.28 0.33 0.55 0.46 0.2 0.55 0.46


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -3.2 -2.2 -2.7 -3.6 -3.2 -4.9 -4.4 -5.4 -4.9 -1.7 -1.8 -1.4 -2.7 -0.6 -1.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 2.8 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 3.5 2.8 2.2 1.6 0 0 0 0 0 3.2 3.2 2.4 3.0 0 2.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.7846 1.5282 1.152 0.9504 1.5805 1.111 2.2431 2.9164 2.5301 2.7346 2.1532 2.4827 1.5273 2.1169 1.6196 1.9335 2.3293 1.844
Actin 0.0031 0.0006 0.0059 0.0004 0.0201 0.0041 0.0364 0.0002 0.0129 0.011 0.0001 0.0033 0.0125 0.0008 0.0146 0.0453 0.0036 0.0049
Bud 0.0026 0.0007 0.0016 0.0036 0.0005 0.0006 0.001 0.0002 0.0002 0.0012 0.0001 0.0001 0.0009 0.0012 0.0015 0.0005 0.006 0.0007
Bud Neck 0.0026 0.0005 0.0008 0.0009 0.0016 0.0017 0.0041 0.0003 0.0006 0.004 0.0006 0.0019 0.0051 0.0005 0.0007 0.001 0.0036 0.0025
Bud Periphery 0.0009 0.0003 0.0007 0.0012 0.0006 0.0002 0.0026 0.0001 0.0001 0.0019 0 0 0.001 0.0003 0.0023 0.0007 0.0076 0.0008
Bud Site 0.0038 0.0059 0.0013 0.001 0.0025 0.0001 0.0034 0.0013 0.0011 0.0063 0.0002 0.0003 0.0057 0.0105 0.0019 0.0029 0.002 0.0008
Cell Periphery 0.0003 0.0001 0.0001 0 0.0002 0 0.0003 0 0 0.0004 0 0 0.0004 0.0001 0.0001 0.0001 0.0001 0
Cytoplasm 0.6943 0.7593 0.7014 0.6763 0.6379 0.6922 0.5775 0.8105 0.6912 0.4941 0.8158 0.7708 0.6502 0.7864 0.7035 0.6182 0.5668 0.6942
Cytoplasmic Foci 0.0196 0.0093 0.0145 0.0041 0.018 0.011 0.0255 0.0043 0.0161 0.0405 0.0052 0.0076 0.0208 0.0053 0.0085 0.0193 0.0484 0.0131
Eisosomes 0.0001 0 0.0001 0 0.0001 0 0.0008 0 0.0001 0.0006 0 0 0.0003 0 0.0001 0.0017 0 0
Endoplasmic Reticulum 0.0059 0.0036 0.006 0.0033 0.0068 0.0031 0.0092 0.0023 0.0034 0.0021 0.0026 0.0026 0.0117 0.0052 0.0042 0.002 0.0045 0.0025
Endosome 0.024 0.0052 0.0209 0.0041 0.0829 0.011 0.0262 0.0017 0.0077 0.028 0.004 0.004 0.0252 0.0053 0.0084 0.0076 0.0353 0.0156
Golgi 0.0029 0.0002 0.0031 0.0001 0.024 0.0008 0.0047 0.0001 0.0026 0.0179 0.0001 0.0002 0.0114 0.0012 0.0021 0.0047 0.0063 0.0093
Lipid Particles 0.003 0.0002 0.0034 0 0.0156 0.0006 0.0088 0 0.0054 0.0647 0 0.0001 0.0095 0.0001 0.0029 0.0217 0.0151 0.0076
Mitochondria 0.0022 0.0003 0.0132 0.0006 0.0207 0.0012 0.0164 0.0002 0.0043 0.0221 0.0004 0.0004 0.0069 0.0005 0.0106 0.0471 0.0053 0.0078
None 0.1311 0.1208 0.0889 0.0533 0.0741 0.1085 0.1277 0.0972 0.1425 0.093 0.0951 0.0445 0.0736 0.067 0.0409 0.0185 0.0208 0.0225
Nuclear Periphery 0.0148 0.0053 0.012 0.0078 0.0189 0.0119 0.0234 0.0027 0.0087 0.0044 0.0041 0.0045 0.0148 0.0069 0.0082 0.0042 0.0116 0.0072
Nucleolus 0.0012 0.0003 0.0004 0.0024 0.0006 0.0004 0.001 0.0001 0.0006 0.0052 0.0002 0.0003 0.0005 0.0002 0.0003 0.0007 0.0012 0.0007
Nucleus 0.0681 0.0761 0.1095 0.2143 0.0562 0.1264 0.0811 0.0757 0.0882 0.1221 0.065 0.1517 0.1261 0.1027 0.1711 0.0732 0.1969 0.1956
Peroxisomes 0.0011 0.0002 0.003 0.0001 0.0024 0.0005 0.0303 0.0001 0.0057 0.051 0.0001 0.0004 0.0041 0.0001 0.0109 0.1225 0.041 0.0044
Punctate Nuclear 0.014 0.009 0.0108 0.0245 0.0072 0.0234 0.0129 0.0017 0.007 0.0259 0.0052 0.0061 0.0106 0.0035 0.0047 0.0066 0.0126 0.0073
Vacuole 0.0032 0.0018 0.0022 0.0017 0.0038 0.0014 0.0046 0.0012 0.0012 0.0025 0.0011 0.001 0.0067 0.0018 0.0023 0.0013 0.0091 0.0016
Vacuole Periphery 0.0014 0.0003 0.0006 0.0004 0.0051 0.0007 0.0022 0.0001 0.0004 0.0011 0.0002 0.0002 0.002 0.0003 0.0004 0.0004 0.0023 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.3342 7.9466 6.6338 13.4271 11.5256 4.4423 14.3121 10.507 12.0307 15.0053
Translational Efficiency 1.3298 2.42 2.431 1.3771 1.6771 4.2213 1.0904 2.1018 1.7275 1.2979

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency
Standard name
Human Ortholog
Description Basic leucine zipper (bZIP) transcription factor
Localization
Cell Percentages cytoplasm (86%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Yap3

Yap3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yap3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available