Standard name
Human Ortholog
Description Essential DNA-binding transcription regulator that binds many loci; involved in transcription activation, repression, chromatin silencing, telomere length maintenance; relocalizes to cytosol under hypoxia; conserved protein with N-terminal BRCT domain, central region with homology to Myb DNA binding domain, and C-terminal Rap1-specific protein-interaction domain (RCT domain); recruits Sir complex to telomeric DNA; present in quiescent cell telomere hyperclusters
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 – – – – – – – – – – – – – – – – – 0 – 1.0 0.55 –
Bud – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Bud Neck – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Bud Site – 0 – – – – – – – – – – – – – – – – – – – – – –
Cell Periphery – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Cytoplasm – 0.06 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Endoplasmic Reticulum – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Endosome – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Golgi – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Mitochondria – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Nucleus – 0.82 – – – – – – – – – – – – – – – – – 0.7 – 0 0 –
Nuclear Periphery – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Nucleolus – 0.13 – – – – – – – – – – – – – – – – – 0.13 – 0 0 –
Peroxisomes – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
SpindlePole – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Vac/Vac Membrane – 0 – – – – – – – – – – – – – – – – – 0.05 – 0 0 –
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 – – – – – – – – – – – – – – – – – 1 – 0 0 –
Bud – 0 – – – – – – – – – – – – – – – – – 6 – 0 0 –
Bud Neck – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Bud Site – 2 – – – – – – – – – – – – – – – – – – – – – –
Cell Periphery – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Cytoplasm – 9 – – – – – – – – – – – – – – – – – 1 – 0 0 –
Endoplasmic Reticulum – 0 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Endosome – 2 – – – – – – – – – – – – – – – – – 1 – 0 0 –
Golgi – 0 – – – – – – – – – – – – – – – – – 1 – 0 0 –
Mitochondria – 2 – – – – – – – – – – – – – – – – – 0 – 0 0 –
Nucleus – 115 – – – – – – – – – – – – – – – – – 124 – 0 0 –
Nuclear Periphery – 5 – – – – – – – – – – – – – – – – – 5 – 0 0 –
Nucleolus – 18 – – – – – – – – – – – – – – – – – 23 – 0 0 –
Peroxisomes – 0 – – – – – – – – – – – – – – – – – 1 – 0 0 –
SpindlePole – 1 – – – – – – – – – – – – – – – – – 1 – 0 0 –
Vac/Vac Membrane – 1 – – – – – – – – – – – – – – – – – 8 – 0 0 –
Unique Cell Count 140 178 1 1
Labelled Cell Count 155 178 1 1


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 9.5 – – – – – – – – – – – – – – – – – – –
Std Deviation (1e-4) – 2.6 – – – – – – – – – – – – – – – – – – –
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin – – – – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – – – – –
Bud Periphery – – – – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – – – – –
Cytoplasmic Foci – – – – – – – – – – – – – – – – – –
Eisosomes – – – – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – – – – –
Lipid Particles – – – – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – – – – –
None – – – – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – – – – –
Punctate Nuclear – – – – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – – – – –
Vacuole Periphery – – – – – – – – – – – – – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 47.3078 46.4597 32.7072 34.1811 33.404 35.5167 43.7634 38.2089 34.585 46.0987
Translational Efficiency 2.0844 1.9666 1.8449 1.6121 2.4083 2.2856 1.7393 1.7181 1.7141 1.6385

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization –
Gene Expression ✔
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rap1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available