Standard name
Human Ortholog
Description Catalytic subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0.06 0.05 0.06 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.07 0.05 0.08 0.05 0 0.06 0.06 0 0.09 0.15 0.17 0.13 0.08 0.12 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.09 0.28 0.28 0.23 0.38 0.34 0.36 0.47 0.49 0.48 0.48 0 0 0.09 0.06 0 0.11 0 0 0 0 0 0
Nucleus 0.87 0.84 0.85 0.88 0.8 0.83 0.75 0.73 0.71 0.69 0.64 0.67 0.84 0.78 0.71 0.73 0.75 0.74 0.73 0.82 0.77 0.73 0.76 0.59
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.19 0.24 0.13 0.1 0.1 0.13 0.16 0.23 0.25 0.26 0.24 0.35 0.2 0.14 0.19 0.08 0.12 0.17 0.18 0.07 0.11 0.18 0.15 0.24
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud 0 1 0 1 0 0 2 9 2 6 4 2 0 0 0 0 1 0 2 0 0 0 1 3
Bud Neck 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0
Bud Site 0 0 1 2 5 13 9 21 23 20 14 25 0 2 1 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 8 4 8 7 19 20 40 29 16 25 14 18 14 36 45 14 7 10 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 1 0 2 2 2 1 0 0 0 0 0 0 0 2 2 0 0 2 0 0 1
Endosome 1 0 0 0 0 0 0 0 1 0 0 0 0 0 1 3 1 0 1 1 3 1 2 5
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 4 1 1 4 0 0 0 0 3
Mitochondria 0 11 65 52 62 155 163 211 175 209 118 194 6 3 24 6 1 9 2 1 7 0 0 0
Nucleus 163 107 197 162 220 340 359 425 267 294 158 272 130 192 186 79 67 60 150 115 193 84 162 159
Nuclear Periphery 6 1 6 2 4 12 15 9 16 11 12 7 0 1 2 1 0 0 0 0 0 0 0 0
Nucleolus 36 30 31 18 28 53 75 133 92 111 59 141 31 35 50 9 11 14 38 9 27 21 31 64
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0
SpindlePole 0 1 1 2 2 0 5 8 5 3 4 3 0 2 1 2 2 0 0 1 0 0 1 6
Vac/Vac Membrane 0 1 3 2 2 2 2 6 1 3 4 3 0 2 3 4 1 0 1 6 10 2 6 19
Unique Cell Count 187 127 233 185 274 410 480 586 375 428 245 408 154 245 261 108 89 81 206 140 253 116 213 270
Labelled Cell Count 214 156 312 249 342 597 672 854 599 682 388 665 181 274 313 122 94 97 206 140 253 116 213 270


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.1 6.3 5.2 5.2 5.1 4.7 4.9 4.8 4.3 4.2 4.3 4.1 6.8 6.9 5.8 8.8 9.8 9.6 7.2 7.4 7.9
Std Deviation (1e-4) 1.4 1.7 1.7 2.4 1.8 1.8 2.0 1.8 1.8 1.5 1.9 1.5 2.1 2.1 1.7 1.7 2.4 2.4 1.4 1.7 1.8
Intensity Change (Log2) – – – -0.0 -0.03 -0.14 -0.1 -0.12 -0.27 -0.3 -0.26 -0.35 0.38 0.4 0.15 0.75 0.92 0.88 0.48 0.51 0.6


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.2 1.7 0.9 2.4 0.9 0.5 1.4 1.2 0.6 2.4 4.3 5.0 3.3 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 -1.4 0 0 0 0 0 0 0 -6.0 -8.3 -5.4 -4.7 -5.3 -3.1
Nucleus 0.9 -1.3 -0.5 -2.9 -3.6 -3.8 -4.5 -5.0 -4.9 0 -1.7 -3.5 -2.5 -1.9 -2.1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -1.1 -1.1 0 0 0 0 0 0 0 1.8 0.3 1.8 -1.3 -0.2 0.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.2319 0.096 0.0274 0.0956 0.1885 0.1727 0.2631 0.0914 0.0504 0.1422 0.1727 0.2343 0.1706 0.0476 0.0565 0.1904 0.1454 0.1838
Bud 0.0561 0.0766 0.4253 0.1567 0.0839 0.0229 0.0247 0.1205 0.3415 0.1701 0.0967 0.0218 0.038 0.0871 0.3945 0.1314 0.0832 0.0229
Bud Neck 0.0764 0.0142 0.0176 0.002 0.162 0.6619 0.0975 0.0094 0.0137 0.0272 0.0737 0.5692 0.1049 0.0099 0.0024 0.001 0.0201 0.5887
Bud Periphery 0.0815 0.0818 0.3707 0.5925 0.5135 0.0595 0.0782 0.0978 0.3847 0.5527 0.4495 0.0768 0.0966 0.067 0.3784 0.5783 0.4675 0.1072
Bud Site 0.3555 0.6051 0.1333 0.0111 0.0231 0.0205 0.2536 0.5787 0.1177 0.0549 0.0531 0.0273 0.3776 0.712 0.1144 0.0067 0.0507 0.042
Cell Periphery 0.0773 0.0082 0.0035 0.0058 0.0058 0.0195 0.0944 0.0131 0.0186 0.0427 0.0298 0.0204 0.1 0.0111 0.022 0.0303 0.0329 0.0275
Cytoplasm 0.0335 0.0537 0.0008 0.0013 0.0033 0.0149 0.018 0.0644 0.0036 0.0063 0.0499 0.0185 0.0046 0.0393 0.013 0.0041 0.0344 0.0168
Cytoplasmic Foci 0.0159 0.0092 0.0005 0.0245 0.0011 0.0068 0.0172 0.003 0.0093 0.0002 0.0092 0.0062 0.0309 0.0014 0.0021 0.0361 0.0115 0.002
Eisosomes 0.0062 0.0023 0.0004 0.001 0.0009 0.001 0.029 0.0012 0.0005 0.0008 0.0014 0.0012 0.0158 0.0003 0.0005 0.0025 0.0133 0.0018
Endoplasmic Reticulum 0.0022 0.0016 0.0001 0.0009 0.0009 0.0005 0.01 0.0005 0.0009 0.0004 0.0014 0.0011 0.0011 0.0004 0.0004 0.0009 0.0012 0.0003
Endosome 0.0023 0.0006 0.0002 0.0004 0.0006 0.0014 0.01 0.0008 0.0069 0 0.0067 0.0026 0.0085 0.0001 0.0011 0.0002 0.0207 0.0004
Golgi 0.0019 0.0012 0.0004 0.0005 0.0004 0.0052 0.006 0.0008 0.003 0.0002 0.0077 0.0028 0.0156 0.0001 0.0044 0.0005 0.0302 0.0013
Lipid Particles 0.0038 0.0017 0.0003 0.0009 0.0002 0.0018 0.0123 0.0006 0.0035 0 0.0197 0.0012 0.0049 0.0001 0.0009 0.0044 0.0114 0.0004
Mitochondria 0.0059 0.0018 0.0051 0.0351 0.0008 0.0015 0.0158 0.0012 0.0059 0.0003 0.0069 0.0014 0.008 0.0002 0.0047 0.0021 0.053 0.0005
None 0.0061 0.0378 0.011 0.0049 0.0002 0.0003 0.016 0.008 0.0049 0.0003 0.0012 0.0024 0.0011 0.0038 0.0003 0.0008 0.0006 0.0005
Nuclear Periphery 0.0114 0.0003 0.0002 0.0005 0.0005 0.0001 0.0031 0.0009 0.0011 0.0002 0.0009 0.0005 0.0006 0.0005 0.0001 0.0003 0.0007 0.0001
Nucleolus 0.0033 0.0006 0.0004 0.0072 0.0026 0.0006 0.004 0.0012 0.0041 0.0001 0.0003 0.0008 0.0019 0.0002 0.0002 0.0001 0.0123 0.0005
Nucleus 0.005 0.0006 0.0005 0.0036 0.0013 0.0005 0.0075 0.0017 0.0063 0.0002 0.0003 0.001 0.0011 0.0175 0.0004 0.0002 0.0009 0.0005
Peroxisomes 0.0104 0.0037 0.0005 0.0006 0.0003 0.0042 0.0097 0.0014 0.0111 0.0001 0.0163 0.0034 0.0065 0.0002 0.0026 0.0064 0.0049 0.0012
Punctate Nuclear 0.0093 0.0007 0.0007 0.0525 0.0007 0.0005 0.0037 0.0016 0.0017 0 0.0014 0.0036 0.0046 0.0006 0.0001 0.0027 0.0009 0.0002
Vacuole 0.0034 0.0021 0.001 0.0019 0.0089 0.0033 0.0241 0.0017 0.0068 0.0009 0.0008 0.0031 0.0068 0.0007 0.0009 0.0005 0.0036 0.0014
Vacuole Periphery 0.0007 0.0003 0.0002 0.0007 0.0005 0.0003 0.002 0.0003 0.0036 0.0001 0.0004 0.0003 0.0005 0 0.0001 0.0001 0.0005 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 28.1679 28.943 25.0564 34.4884 34.0022 30.6332 37.1655 35.8158 39.3844 40.1641
Translational Efficiency 0.7707 0.6963 0.6484 0.5358 0.5301 0.6187 0.5212 0.49 0.4489 0.4972

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Snf2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available