Supplemental Files

• Table S1. Proteome Dynamics

  Protein localization and concentration for cell cycle phases G1 Pre-START, G1 Post-START, S/G2, Metaphase, Anaphase, Telophase

  Litsios et al. Table S1 - Proteome Dynamics.xlsx

• Table S2. Differential Scaling

  Functional enrichment analysis of proteins based on scaling of their abundance with cell size during G1, and type of differential scaling for proteins involved in glycolysis, ergosterol biosynthesis, and mitochondrial respiration

  Litsios et al. Table S2 - Differential Scaling.xlsx

• Table S3. Gene Expression Dynamics and Multi-level Regulation

  Transcript levels and translational efficiency dynamics for cell cycle phases G1 Post-START, S/G2, Metaphase, Anaphase, Telophase, and list of genes for which cell-cycle periodicity was identified at all three levels (protein concentration, transcript level, translational efficiency)

  Litsios et al. Table S3 - Gene Expression Dynamics and Multi-level Regulation.xlsx

• Table S4. Periodic Human Genes with Periodic Yeast Orthologs

  List of 45 human proteins identified as cell cycle-periodic in Mahdessian et al. (2021) for which at least one of their yeast orthologs was identified to be periodic here

  Litsios et al. Table S4 - Periodic Human Genes with Periodic Yeast Orthologs.xlsx

• Table S5. Enrichment Analyses of the Periodic Proteome

  Litsios et al. Table S5 - Enrichment Analyses of the Periodic Proteome.xlsx

• Table S6. Diagnostic Set for Ymr295c Protein Interactions Screen

  Litsios et al. Table S6 - Diagnostic Set for Ymr295c Protein Interactions Screen.xlsx