Endocytosis

• Legend
  • actin: Actin patch
  • coat: Cortical patch
  • LE: Late endosome
  • vac: Vacuole
  • gw: Genome wide screen
  • secondary: secondary screen
  • SMF: Single mutant fitness
  • SD: Standard deviation
• Columns
  • A-G: strain information
  • H-AM: p-value, penetrance, cell count and well count data for each marker and screen type
  • AN-BG: total cell count, total well count, combined mean penetrance, penetrance SD data for each marker
  • BH-DE: data on phenotype fractions for each phenotype and screen type
  • DF-GK: combined phenotype fraction, and phenotype fraction SD, (stringent) SPM calls for each phenotype

Cell Cycle Omics

• Legend
  • GE: Gene Expression
  • TE: Translational Efficiency
  • PA: Protein Abundance
  • Loc: Protein Localization
  • R1, R2 and R3: Biological replicate 1, 2 and 3
• Columns
  • A-B: Gene information
  • C-O: Gene Expression data for each cell cycle phase across two biological replicates
  • P-AB: Translational Efficiency for each cell cycle phase data across two biological replicates
  • AC-AW: Protein Abundance data for each cell cycle phase across three biological replicates
  • AX-QF: Protein Localization data for each compartment and cell cycle phase across three biological replicates
  • QG-QU: Cell count data for each cell cycle phase across three biological replicates

CYCLoPs

• Sheets
  • LOCscore_ensLOC: quantitative measurement of localization in each ensLOC screen
  • LOCscore_DeepLoc: quantitative measurement of localization in each DeepLoc screen
  • Zscore: quantitative localization changes in sub-cellular compartments
  • Abundance: GFP intensity measures of the protein in each screen
    Columns
    • [screen]_Mean - Mean Cell GFP Intensity (1e^-4)
    • [screen]_Stdev - Standard Deviation (1e^-4)
    • [screen]_Change - Intensity Change (Log₂)
• Notes
  • strains with signal below threshold were not filtered from the dataset
  • ensLOC and DeepLoc scores that are less than 0.05 are rounded-down to 0