Standard name
Human Ortholog
Description RNA polymerase I largest subunit A190
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.09 0 0.06 0 0 0 0 0 – 0 0 0.11 0.07 0.08 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.5 0.7 0.35 0.35 0.3 0.28 0.21 0.13 0.2 – 0.15 0.16 0.46 0.39 0.46 0.08 0.07 0.05 0 0 0 0 0 0
Nucleus 0.06 0.09 0.07 0.1 0.06 0.07 0.06 0.05 0.05 – 0 0 0.07 0.1 0 0.13 0.05 0.08 0.05 0.05 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.96 0.84 0.94 0.79 0.87 0.9 0.9 0.89 0.92 – 0.9 0.9 0.84 0.82 0.88 0.91 0.87 0.86 0.87 0.85 0.83 0.87 0.81 0.72
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0.07 0.07 0.12 0.11 – 0.16 0.16 0 0 0 0 0 0 0 0 0 0 0 0.06
Vac/Vac Membrane 0 0 0 0.06 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 1 1 0 0 1
Bud 0 0 0 0 1 1 0 2 3 – 0 0 0 0 0 0 0 0 0 0 1 0 1 4
Bud Neck 1 0 0 1 0 4 2 11 2 – 2 4 0 0 0 0 0 0 1 1 3 0 0 2
Bud Site 0 0 1 0 1 2 9 8 18 – 7 15 0 1 1 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 1 0 0 – 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Cytoplasm 0 25 5 19 14 6 8 16 4 – 4 6 10 14 18 3 5 4 0 2 3 0 2 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 2 0 0 0 0 0 0
Endosome 0 0 2 3 2 4 3 8 0 – 0 1 0 4 5 0 2 0 0 0 3 0 1 3
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 0 1 0 1 4
Mitochondria 66 186 136 112 112 128 124 95 89 – 55 64 41 79 104 9 8 5 1 0 5 0 4 8
Nucleus 8 23 29 34 24 31 35 33 23 – 11 12 6 21 5 14 6 8 6 14 16 3 7 3
Nuclear Periphery 0 1 0 0 0 1 0 1 0 – 1 0 1 0 0 0 0 0 0 2 1 0 0 1
Nucleolus 126 222 371 255 324 404 531 635 413 – 322 366 76 168 200 96 103 88 119 225 343 71 157 167
Peroxisomes 0 1 5 3 3 15 14 32 7 – 12 21 1 2 5 0 2 1 0 0 2 0 1 1
SpindlePole 4 0 5 9 9 32 40 82 49 – 56 65 0 4 9 3 3 2 5 3 17 1 4 14
Vac/Vac Membrane 0 3 4 21 4 2 3 1 3 – 0 2 0 2 1 0 3 1 0 6 8 2 9 13
Unique Cell Count 131 264 394 324 371 450 592 713 449 358 406 90 204 228 106 118 102 137 265 415 83 196 232
Labelled Cell Count 205 461 558 457 494 630 770 924 611 470 556 135 296 349 125 134 111 137 265 415 83 196 232


Nucleolus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 46.3 53.2 29.1 29.0 24.2 18.3 16.3 15.1 12.8 – 12.3 11.6 34.8 30.0 25.8 36.7 48.9 46.9 35.9 37.5 38.3
Std Deviation (1e-4) 16.5 32.0 10.2 11.0 10.9 6.5 5.3 5.4 4.7 – 4.5 4.3 20.4 15.3 12.7 17.6 25.1 21.7 15.0 15.1 17.8
Intensity Change (Log2) – – – -0.01 -0.26 -0.67 -0.84 -0.94 -1.18 – -1.24 -1.32 0.26 0.04 -0.17 0.33 0.75 0.69 0.3 0.37 0.4

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000204060WT3HU80HU120HU1600204060WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30204060WT1AF100AF140AF1800204060
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 3.7 – 0 3.5 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 3.4 2.2 0.1 0.1 1.1 0 – 0 0.3 0 3.7 4.2 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 -1.3 -1.9 -4.7 -8.3 -4.8 – -6.0 -6.1 2.0 1.0 2.7 -5.2 -5.9 -5.9
Nucleus 1.5 -0.5 -0.3 -0.9 -1.9 -1.3 – -2.6 -2.8 -0.2 1.2 -2.7 1.9 -0.9 0.2
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus -6.2 -3.3 -2.3 -2.5 -2.8 -1.2 – -2.1 -2.1 -3.1 -4.6 -2.8 -1.3 -2.5 -2.7
Peroxisomes 0 0 2.0 1.2 2.9 0.4 – 1.9 3.1 0 0 0 0 0 0
SpindlePole 1.5 1.2 4.1 4.0 6.1 5.7 – 7.2 7.4 0 0 2.2 0 0 0
Vacuole 4.0 0 0 0 0 0 – 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 28.7588 42.2405 38.0797 37.1282 29.5623 37.4897 34.7008 45.8436 40.7704 41.7061 38.9748 38.5807 38.0384 50.5911 35.6595 31.4843 27.7868 34.4908
Actin 0.041 0.0002 0.0028 0.012 0.0447 0.0026 0.0002 0.0002 0 0 0 0 0.0695 0 0 0 0.1237 0
Bud 0.0004 0 0.0001 0.0002 0.0007 0.0001 0.0001 0 0 0 0 0 0.0001 0 0 0 0.0006 0
Bud Neck 0.0012 0 0.0002 0.0008 0.0019 0.0001 0.0001 0.0003 0 0 0 0.0001 0.0001 0 0 0 0.0006 0
Bud Periphery 0.0005 0.0001 0.0001 0.0004 0.0014 0.0001 0.0001 0 0 0 0 0 0.0002 0 0 0 0.0011 0
Bud Site 0.0019 0.0001 0.0009 0.0016 0.0027 0.0003 0.0005 0.0001 0 0 0 0.0001 0.0002 0 0 0 0.003 0
Cell Periphery 0.0004 0.0001 0.0002 0.0003 0.0009 0.0001 0.0002 0.0001 0 0.0001 0.0001 0.0001 0 0 0.0001 0.0001 0.0002 0.0001
Cytoplasm 0.0048 0 0.0001 0.0002 0.0012 0.0002 0 0 0 0 0 0 0.0001 0 0 0 0.0005 0
Cytoplasmic Foci 0.0294 0.0001 0.0028 0.0143 0.01 0.0075 0.0097 0.0022 0.0015 0.0001 0.0001 0.0002 0.0037 0 0.0008 0.0027 0.0455 0.0001
Eisosomes 0.0029 0.0002 0.0001 0.0003 0.0006 0.0001 0.0001 0 0 0 0 0 0.0002 0 0 0 0.0007 0
Endoplasmic Reticulum 0.003 0 0.0001 0.0003 0.0048 0.001 0 0 0 0 0 0 0.0001 0 0 0 0.0016 0
Endosome 0.0195 0 0.0025 0.0038 0.0155 0.0037 0.0001 0.0006 0 0 0 0 0.0009 0 0 0 0.0117 0
Golgi 0.0064 0 0.004 0.0032 0.006 0.0017 0.0004 0.0011 0 0 0 0 0.0033 0 0 0 0.0259 0
Lipid Particles 0.0141 0.0001 0.0039 0.0043 0.0221 0.0051 0.0045 0.0023 0.0009 0.0001 0.0003 0.0003 0.0082 0.0001 0.0029 0.0015 0.0485 0.0002
Mitochondria 0.0132 0.0106 0.0105 0.0076 0.1402 0.0046 0.0044 0.0035 0.0003 0.0003 0.0131 0.0003 0.0007 0.0005 0.001 0.0143 0.0095 0.0003
None 0.0134 0 0.0002 0.001 0.001 0.0002 0.0002 0 0 0 0 0 0.0006 0 0 0 0.0014 0
Nuclear Periphery 0.0297 0.0001 0.0008 0.0149 0.0054 0.0016 0.0002 0 0.0001 0 0 0 0.0003 0 0 0 0.0057 0
Nucleolus 0.7504 0.8729 0.9168 0.8604 0.676 0.917 0.8879 0.9034 0.9176 0.9036 0.9318 0.9401 0.8416 0.9683 0.9532 0.9634 0.6454 0.95
Nucleus 0.039 0.1139 0.0512 0.0691 0.0382 0.0504 0.0488 0.0819 0.077 0.0957 0.0536 0.0566 0.0471 0.0309 0.0414 0.0167 0.021 0.0491
Peroxisomes 0.007 0 0.0013 0.0012 0.0075 0.0014 0.0019 0.0006 0 0 0.0003 0.0001 0.0216 0 0.0001 0.0005 0.04 0
Punctate Nuclear 0.0185 0.0012 0.0003 0.0012 0.0007 0.0013 0.04 0.003 0.0023 0 0.0001 0.0019 0.0013 0 0.0001 0.0001 0.0122 0.0001
Vacuole 0.0011 0.0001 0.0003 0.0008 0.0106 0.0004 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001 0 0 0.0001 0.0002 0.0003 0
Vacuole Periphery 0.0022 0.0002 0.0009 0.002 0.0079 0.0004 0.0004 0.0003 0.0001 0 0.0005 0.0001 0.0001 0 0.0003 0.0004 0.0009 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 236.6963 209.716 198.6991 184.4197 179.0055 147.2599 161.6783 146.0125 108.5402 176.3633
Translational Efficiency 0.6318 0.743 0.6467 0.5464 0.5779 0.7199 0.6682 0.4771 0.5488 0.5153

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
212 159 1421 1381 1494 1822 201 173 1706 1981 1622 1554

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1274.68 2972.94 2797.22 2547.85 2187.80 2576.25 3196.99 3120.63 2074.33 2608.09 2846.76 2611.62
Standard Deviation 409.64 872.25 735.84 857.88 732.20 767.70 758.80 958.57 762.29 784.05 750.38 888.13
Intensity Change Log 2 — 1.221755 1.133859 0.999145 — 0.235792 0.547233 0.512356 — 0.680471 0.791764 0.711156

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000321 0.000219 0.000317 0.000550 0.000293 0.000327 0.000322 0.000459 0.000296 0.000318 0.000318 0.000540
Bud Neck 0.003041 0.000841 0.001487 0.006585 0.000678 0.001177 0.002146 0.004281 0.000972 0.001150 0.001569 0.006329
Bud Site 0.002158 0.000704 0.000556 0.002289 0.000485 0.000487 0.000905 0.001323 0.000693 0.000505 0.000599 0.002182
Cell Periphery 0.000028 0.000009 0.000014 0.000131 0.000024 0.000055 0.000017 0.000038 0.000025 0.000052 0.000014 0.000121
Cytoplasm 0.000327 0.000059 0.000045 0.000974 0.000614 0.000201 0.000061 0.000184 0.000578 0.000190 0.000047 0.000887
Cytoplasmic Foci 0.021866 0.011417 0.009520 0.021733 0.015873 0.007396 0.015047 0.014975 0.016617 0.007719 0.010205 0.020981
Eisosomes 0.000314 0.000198 0.000386 0.000268 0.000451 0.000407 0.000251 0.000193 0.000434 0.000391 0.000370 0.000260
Endoplasmic Reticulum 0.000299 0.000055 0.000063 0.000157 0.000098 0.000125 0.000053 0.000069 0.000123 0.000120 0.000062 0.000148
Endosome 0.000107 0.000008 0.000015 0.000987 0.000019 0.000208 0.000017 0.000027 0.000030 0.000192 0.000015 0.000880
Golgi 0.000454 0.000112 0.000215 0.001096 0.000159 0.000150 0.000369 0.000301 0.000196 0.000147 0.000234 0.001008
Lipid Particles 0.000101 0.000013 0.000010 0.000519 0.000031 0.000111 0.000016 0.000019 0.000040 0.000103 0.000011 0.000463
Mitochondria 0.002683 0.000596 0.001489 0.003474 0.000828 0.001245 0.002649 0.002308 0.001058 0.001193 0.001633 0.003344
Mitotic Spindle 0.040743 0.004307 0.016313 0.026738 0.001885 0.002733 0.016424 0.010262 0.006714 0.002859 0.016327 0.024904
None 0.000475 0.000377 0.000369 0.001037 0.001816 0.000738 0.000305 0.000673 0.001650 0.000709 0.000361 0.000997
Nuclear Periphery 0.002435 0.000029 0.000065 0.000498 0.000030 0.000082 0.000123 0.000259 0.000329 0.000078 0.000072 0.000471
Nuclear Periphery Foci 0.000811 0.000039 0.000044 0.000585 0.000226 0.000608 0.000053 0.000084 0.000298 0.000563 0.000045 0.000529
Nucleolus 0.521178 0.472900 0.509631 0.610389 0.503430 0.535481 0.530150 0.618303 0.505635 0.530458 0.512174 0.611270
Nucleus 0.091620 0.207981 0.104263 0.195496 0.164229 0.224308 0.066702 0.207148 0.155206 0.222997 0.099609 0.196793
Peroxisomes 0.309340 0.299622 0.354519 0.121033 0.307899 0.222813 0.363531 0.137356 0.308078 0.228978 0.355635 0.122851
Vacuole 0.000920 0.000202 0.000276 0.002726 0.000576 0.000644 0.000357 0.000580 0.000619 0.000608 0.000286 0.002487
Vacuole Periphery 0.000779 0.000313 0.000402 0.002732 0.000356 0.000705 0.000504 0.001159 0.000409 0.000673 0.000415 0.002557

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.63 0.10 -5.89 -10.69 -8.98 -1.30 -0.46 -3.62 -3.13 -1.72 -0.89 -0.94 -8.87 -9.26 -8.92
Bud Neck 3.47 2.68 -6.24 -11.99 -11.87 -4.25 -3.81 -3.16 -2.87 -2.22 -1.50 -4.95 -13.04 -12.56 -11.73
Bud Site 0.97 1.24 -0.68 -4.28 -10.42 0.06 -2.95 -3.67 -3.73 -2.09 0.97 0.44 -7.98 -10.61 -10.59
Cell Periphery 3.10 2.57 -6.80 -8.13 -7.95 -1.91 0.69 -2.09 0.66 -2.60 -1.80 2.17 -7.18 -3.92 -8.10
Cytoplasm 1.37 1.63 -2.90 -4.59 -4.84 1.22 1.55 1.12 -0.48 -2.50 1.29 1.70 -0.92 -4.12 -4.93
Cytoplasmic Foci 1.11 3.13 -0.81 -1.83 -7.01 4.88 -0.30 -0.09 -2.69 0.14 5.19 3.74 -3.28 -7.86 -6.75
Eisosomes 4.28 -2.50 1.55 -1.97 3.81 1.56 8.42 10.08 7.91 2.73 1.71 2.81 6.11 4.41 3.98
Endoplasmic Reticulum 3.70 3.84 2.08 -4.14 -8.02 -0.77 3.69 1.30 1.28 -2.39 0.07 5.05 -2.10 -1.10 -8.21
Endosome 3.50 3.46 -2.18 -2.44 -2.43 -1.79 0.15 -1.28 1.41 -1.32 -1.68 1.90 -2.40 -1.80 -2.45
Golgi 6.88 5.47 -2.09 -3.24 -2.91 0.27 -4.74 -2.98 -3.70 0.90 1.28 -1.20 -3.02 -3.22 -2.88
Lipid Particles 2.70 3.87 -0.89 -1.08 -1.11 -1.59 1.39 0.54 1.75 -1.07 -1.40 3.01 -1.03 -0.84 -1.12
Mitochondria 4.92 2.76 -1.66 -9.64 -6.54 -1.87 -1.38 -5.00 -3.10 0.17 -0.63 -3.05 -8.50 -6.67 -5.48
Mitotic Spindle 4.77 3.38 1.54 -6.21 -4.20 -1.09 -4.45 -1.91 -1.70 1.29 3.20 -5.76 -7.86 -9.74 -3.80
None 1.75 1.36 -7.61 -8.92 -7.38 1.48 2.10 1.54 0.22 -4.05 1.47 2.06 0.96 -2.53 -7.88
Nuclear Periphery 1.08 1.06 0.85 -8.31 -7.71 -3.50 -3.45 -3.25 -2.64 -2.06 0.90 0.91 -0.67 -7.69 -7.94
Nuclear Periphery Foci 2.48 2.48 0.58 -1.84 -1.84 -1.10 1.51 0.98 1.54 -1.54 -0.83 2.33 -0.74 0.16 -1.87
Nucleolus 2.21 0.77 -4.84 -6.86 -9.99 -4.25 -1.54 -5.65 -3.96 -3.82 -3.49 -0.71 -11.04 -8.12 -10.66
Nucleus -5.68 -1.44 -10.59 0.36 -12.71 -8.03 10.83 -2.51 0.67 -7.32 -9.68 9.79 -6.11 2.62 -14.43
Peroxisomes 0.51 -3.09 13.18 10.61 36.03 12.04 -4.06 16.26 8.68 14.67 11.84 -6.69 30.32 19.92 38.83
Vacuole 2.79 2.99 -2.88 -4.13 -4.16 -0.21 1.18 -0.91 -0.74 -1.49 0.06 2.21 -3.47 -3.39 -4.27
Vacuole Periphery 3.68 3.10 -3.48 -4.50 -4.35 -1.69 -2.15 -6.48 -2.22 -4.77 -1.39 -0.22 -4.53 -3.63 -4.52
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description RNA polymerase I largest subunit A190
Localization
Cell Percentages nucleolus (97%)
Cell Cycle Regulation No
Subcompartmental Group nucleolus-2

Rpa190

Rpa190


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpa190-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available