| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 3 | 3 | 1 |
| Bud | 0 | 2 | 3 | 0 | 2 | 5 | 5 | 14 | 5 | 5 | 11 | 7 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 3 | 3 |
| Bud Neck | 0 | 0 | 6 | 2 | 2 | 7 | 8 | 9 | 1 | 1 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
| Bud Site | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
| Cell Periphery | 3 | 2 | 2 | 4 | 3 | 5 | 1 | 1 | 2 | 4 | 3 | 3 | 1 | 0 | 1 | 9 | 6 | 10 | 0 | 0 | 6 | 0 | 0 | 0 |
| Cytoplasm | 177 | 259 | 441 | 384 | 437 | 536 | 602 | 594 | 401 | 375 | 308 | 314 | 210 | 305 | 320 | 234 | 161 | 195 | 171 | 239 | 335 | 184 | 228 | 247 |
| Endoplasmic Reticulum | 2 | 0 | 1 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 11 | 7 | 12 | 0 | 1 | 1 | 1 | 1 | 4 |
| Endosome | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 3 | 0 | 0 | 1 | 2 | 0 | 2 | 1 |
| Golgi | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| Mitochondria | 0 | 10 | 3 | 14 | 20 | 72 | 105 | 149 | 138 | 126 | 183 | 146 | 1 | 1 | 8 | 7 | 1 | 4 | 3 | 13 | 24 | 3 | 6 | 9 |
| Nucleus | 1 | 1 | 0 | 1 | 1 | 3 | 2 | 2 | 3 | 3 | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Nuclear Periphery | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Nucleolus | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| SpindlePole | 0 | 0 | 1 | 0 | 0 | 2 | 6 | 5 | 3 | 6 | 3 | 6 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 3 | 1 | 0 | 0 |
| Vac/Vac Membrane | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 0 | 1 | 0 | 5 | 6 | 2 | 0 | 3 | 2 | 1 | 1 | 5 |
| Unique Cell Count | 182 | 265 | 446 | 390 | 448 | 557 | 640 | 666 | 442 | 434 | 402 | 381 | 211 | 311 | 323 | 248 | 173 | 202 | 183 | 265 | 399 | 204 | 255 | 282 |
| Labelled Cell Count | 187 | 275 | 458 | 410 | 466 | 632 | 733 | 781 | 555 | 521 | 517 | 484 | 214 | 314 | 335 | 274 | 188 | 227 | 183 | 265 | 399 | 204 | 255 | 282 |
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 4.8 | 3.6 | 3.2 | 3.1 | 3.4 | 3.0 | 2.9 | 3.1 | 2.6 | 2.7 | 2.6 | 2.5 | 4.2 | 4.4 | 4.0 | 6.1 | 7.1 | 6.6 | 4.6 | 4.6 | 5.1 |
| Std Deviation (1e-4) | 0.5 | 0.5 | 0.7 | 0.9 | 1.3 | 1.1 | 1.2 | 1.7 | 1.1 | 2.3 | 1.0 | 1.2 | 1.3 | 1.2 | 1.1 | 1.3 | 2.5 | 2.2 | 1.5 | 1.6 | 1.6 |
| Intensity Change (Log2) | – | – | – | -0.05 | 0.11 | -0.07 | -0.12 | -0.04 | -0.32 | -0.22 | -0.3 | -0.35 | 0.39 | 0.46 | 0.34 | 0.94 | 1.15 | 1.05 | 0.53 | 0.53 | 0.68 |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | 0.039 | 0.0004 | 0.0134 | 0.0495 | 0.0438 | 0.0117 | – | – | – | – | – | – | 0.0109 | 0.0002 | 0.0042 | 0.0027 | 0.01 | 0.0007 |
| Bud | 0.0017 | 0.0008 | 0.0009 | 0.0081 | 0.0006 | 0.0002 | – | – | – | – | – | – | 0.0052 | 0.0001 | 0.008 | 0.0001 | 0.0143 | 0.0017 |
| Bud Neck | 0.0027 | 0.0003 | 0.0032 | 0.001 | 0.0041 | 0.0012 | – | – | – | – | – | – | 0.0002 | 0.0001 | 0.0004 | 0.0001 | 0.0003 | 0.001 |
| Bud Periphery | 0.005 | 0.0007 | 0.0012 | 0.0089 | 0.0018 | 0.0003 | – | – | – | – | – | – | 0.0065 | 0.0001 | 0.0135 | 0.0001 | 0.0157 | 0.0007 |
| Bud Site | 0.0079 | 0.0124 | 0.0109 | 0.0045 | 0.0012 | 0.0012 | – | – | – | – | – | – | 0.0034 | 0.0012 | 0.0103 | 0.0001 | 0.0008 | 0.0001 |
| Cell Periphery | 0.001 | 0.0006 | 0.0006 | 0.0006 | 0.0004 | 0.0001 | – | – | – | – | – | – | 0.0004 | 0.0001 | 0.0009 | 0.0001 | 0.0003 | 0.0001 |
| Cytoplasm | 0.1771 | 0.3278 | 0.2384 | 0.2671 | 0.2663 | 0.3566 | – | – | – | – | – | – | 0.0969 | 0.2531 | 0.1755 | 0.1711 | 0.1759 | 0.2112 |
| Cytoplasmic Foci | 0.0128 | 0.0073 | 0.0151 | 0.0104 | 0.0107 | 0.0194 | – | – | – | – | – | – | 0.0077 | 0.0045 | 0.0057 | 0.0078 | 0.02 | 0.014 |
| Eisosomes | 0.0012 | 0.0001 | 0.0004 | 0.0027 | 0.0013 | 0.0002 | – | – | – | – | – | – | 0.0002 | 0.0001 | 0.0002 | 0.0003 | 0.0001 | 0 |
| Endoplasmic Reticulum | 0.005 | 0.0025 | 0.003 | 0.0021 | 0.0038 | 0.0017 | – | – | – | – | – | – | 0.001 | 0.0012 | 0.0015 | 0.0003 | 0.0008 | 0.0005 |
| Endosome | 0.0101 | 0.0025 | 0.009 | 0.0061 | 0.0059 | 0.0031 | – | – | – | – | – | – | 0.0013 | 0.0014 | 0.0025 | 0.0007 | 0.0011 | 0.0013 |
| Golgi | 0.0039 | 0.0003 | 0.0039 | 0.007 | 0.0072 | 0.0016 | – | – | – | – | – | – | 0.0007 | 0.0001 | 0.0007 | 0.0002 | 0.0003 | 0.0002 |
| Lipid Particles | 0.004 | 0.0017 | 0.0077 | 0.0027 | 0.0138 | 0.0026 | – | – | – | – | – | – | 0.0038 | 0.0002 | 0.001 | 0.0003 | 0.0005 | 0.0002 |
| Mitochondria | 0.0031 | 0.0005 | 0.0102 | 0.0972 | 0.0348 | 0.0017 | – | – | – | – | – | – | 0.0009 | 0.0002 | 0.0014 | 0.0001 | 0.0016 | 0.0008 |
| None | 0.7013 | 0.6364 | 0.6593 | 0.5134 | 0.5908 | 0.5887 | – | – | – | – | – | – | 0.8484 | 0.7337 | 0.7604 | 0.8144 | 0.738 | 0.7603 |
| Nuclear Periphery | 0.0037 | 0.0005 | 0.0039 | 0.0012 | 0.0013 | 0.0005 | – | – | – | – | – | – | 0.0004 | 0.0005 | 0.0018 | 0.0001 | 0.0012 | 0.0003 |
| Nucleolus | 0.0005 | 0.0002 | 0.0009 | 0.0007 | 0.0004 | 0.0003 | – | – | – | – | – | – | 0.0004 | 0.0001 | 0.0005 | 0.0001 | 0.0013 | 0.0003 |
| Nucleus | 0.0025 | 0.0019 | 0.002 | 0.0032 | 0.0011 | 0.0008 | – | – | – | – | – | – | 0.0008 | 0.0013 | 0.0024 | 0.0003 | 0.0035 | 0.0014 |
| Peroxisomes | 0.0024 | 0.0002 | 0.0101 | 0.0041 | 0.0071 | 0.0038 | – | – | – | – | – | – | 0.0089 | 0.0001 | 0.0032 | 0.0005 | 0.0073 | 0.0015 |
| Punctate Nuclear | 0.0088 | 0.0011 | 0.0036 | 0.0053 | 0.0018 | 0.0038 | – | – | – | – | – | – | 0.0011 | 0.0008 | 0.0041 | 0.0003 | 0.0055 | 0.0029 |
| Vacuole | 0.0046 | 0.0017 | 0.0017 | 0.0025 | 0.0011 | 0.0004 | – | – | – | – | – | – | 0.0008 | 0.0007 | 0.0014 | 0.0003 | 0.0011 | 0.0006 |
| Vacuole Periphery | 0.0016 | 0.0001 | 0.0007 | 0.0014 | 0.0004 | 0.0001 | – | – | – | – | – | – | 0.0001 | 0.0001 | 0.0004 | 0 | 0.0004 | 0.0002 |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 3.986 | 2.5915 | 2.1634 | 4.981 | 3.7586 | 2.8973 | 4.9948 | 4.4212 | 5.5388 | 4.7585 |
| Translational Efficiency | – | – | – | – | – | – | – | – | – | – |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | ✘ |
| Gene Expression | ✘ |
| Translational Efficiency | – |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 1480 | 1014 | 2115 | 997 | 1806 | 1277 | 158 | 568 | 3286 | 2291 | 2273 | 1565 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 606.05 | 692.73 | 911.79 | 797.75 | 657.84 | 715.01 | 902.26 | 794.60 | 634.51 | 705.15 | 911.13 | 796.61 |
| Standard Deviation | 71.77 | 93.17 | 106.04 | 98.81 | 72.85 | 91.23 | 83.92 | 103.40 | 76.82 | 92.76 | 104.69 | 100.51 |
| Intensity Change Log 2 | — | 0.192856 | 0.589265 | 0.396500 | — | 0.120227 | 0.455806 | 0.272492 | — | 0.155510 | 0.521343 | 0.333287 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000106 | 0.001167 | 0.000081 | 0.000627 | 0.000166 | 0.000529 | 0.000277 | 0.000985 | 0.000139 | 0.000811 | 0.000095 | 0.000757 |
| Bud Neck | 0.016322 | 0.037793 | 0.005047 | 0.011844 | 0.017987 | 0.037265 | 0.006398 | 0.007658 | 0.017237 | 0.037499 | 0.005141 | 0.010325 |
| Bud Site | 0.005012 | 0.017431 | 0.013213 | 0.051227 | 0.006067 | 0.022387 | 0.003444 | 0.024860 | 0.005592 | 0.020193 | 0.012534 | 0.041657 |
| Cell Periphery | 0.000157 | 0.000157 | 0.000077 | 0.000165 | 0.000103 | 0.000170 | 0.000289 | 0.000123 | 0.000127 | 0.000164 | 0.000092 | 0.000150 |
| Cytoplasm | 0.543123* | 0.408663* | 0.546694* | 0.466524* | 0.483094* | 0.413383* | 0.273668* | 0.479367* | 0.510131* | 0.411294* | 0.527715* | 0.471185* |
| Cytoplasmic Foci | 0.189078* | 0.277497* | 0.006558 | 0.022944 | 0.222348* | 0.219955* | 0.047693 | 0.050310 | 0.207363* | 0.245423* | 0.009418 | 0.032876 |
| Eisosomes | 0.000167 | 0.000151 | 0.000014 | 0.000048 | 0.000139 | 0.000155 | 0.000171 | 0.000062 | 0.000152 | 0.000153 | 0.000025 | 0.000053 |
| Endoplasmic Reticulum | 0.000516 | 0.000440 | 0.000927 | 0.001788 | 0.000925 | 0.001017 | 0.004040 | 0.001664 | 0.000741 | 0.000762 | 0.001143 | 0.001743 |
| Endosome | 0.013877 | 0.037652 | 0.001254 | 0.008113 | 0.009755 | 0.028781 | 0.007748 | 0.014370 | 0.011612 | 0.032707 | 0.001705 | 0.010384 |
| Golgi | 0.002221 | 0.006297 | 0.000048 | 0.003537 | 0.002531 | 0.006324 | 0.000136 | 0.010481 | 0.002392 | 0.006312 | 0.000054 | 0.006057 |
| Lipid Particles | 0.008549 | 0.007109 | 0.000371 | 0.003362 | 0.009122 | 0.009195 | 0.006070 | 0.001831 | 0.008864 | 0.008272 | 0.000767 | 0.002806 |
| Mitochondria | 0.003225 | 0.012973 | 0.000412 | 0.005713 | 0.007616 | 0.011599 | 0.000728 | 0.008373 | 0.005638 | 0.012207 | 0.000434 | 0.006679 |
| Mitotic Spindle | 0.001550 | 0.003748 | 0.002196 | 0.059131 | 0.001934 | 0.014993 | 0.000486 | 0.015693 | 0.001761 | 0.010016 | 0.002078 | 0.043365 |
| None | 0.008728 | 0.004105 | 0.006062 | 0.003914 | 0.002412 | 0.003400 | 0.003293 | 0.006905 | 0.005256 | 0.003712 | 0.005870 | 0.005000 |
| Nuclear Periphery | 0.000432 | 0.000392 | 0.000726 | 0.001228 | 0.000463 | 0.000490 | 0.001902 | 0.001162 | 0.000449 | 0.000447 | 0.000808 | 0.001204 |
| Nuclear Periphery Foci | 0.000308 | 0.000382 | 0.000617 | 0.001876 | 0.000227 | 0.000260 | 0.002521 | 0.001455 | 0.000263 | 0.000314 | 0.000749 | 0.001723 |
| Nucleolus | 0.002409 | 0.003769 | 0.000180 | 0.000592 | 0.000974 | 0.002024 | 0.001704 | 0.000535 | 0.001620 | 0.002796 | 0.000286 | 0.000571 |
| Nucleus | 0.148365* | 0.075002 | 0.382574* | 0.214076* | 0.179805* | 0.121604 | 0.502600* | 0.151779* | 0.165645* | 0.100978 | 0.390917* | 0.191466* |
| Peroxisomes | 0.003364 | 0.021959 | 0.000111 | 0.000888 | 0.007168 | 0.012580 | 0.000921 | 0.002926 | 0.005454 | 0.016731 | 0.000167 | 0.001628 |
| Vacuole | 0.051569 | 0.080254 | 0.032685 | 0.141609 | 0.046269 | 0.091389 | 0.135455 | 0.213977* | 0.048656 | 0.086460 | 0.039829 | 0.167874 |
| Vacuole Periphery | 0.000923 | 0.003060 | 0.000154 | 0.000793 | 0.000894 | 0.002503 | 0.000455 | 0.005484 | 0.000907 | 0.002750 | 0.000175 | 0.002495 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -1.34 | -0.04 | -4.77 | 0.87 | -5.06 | -1.47 | -3.72 | -1.62 | 0.02 | -0.76 | -1.79 | 0.75 | -3.75 | 0.82 | -3.97 |
| Bud Neck | -6.92 | 9.07 | 6.16 | 10.20 | -2.29 | -6.72 | 4.43 | 9.24 | 11.64 | -0.09 | -9.60 | 12.80 | 10.45 | 15.19 | -1.85 |
| Bud Site | -8.24 | -3.55 | -5.34 | -1.09 | -3.08 | -6.30 | 2.01 | -2.68 | 2.13 | -3.57 | -9.16 | -3.10 | -5.84 | 0.67 | -3.22 |
| Cell Periphery | 0.11 | 8.13 | 3.46 | 1.68 | -4.77 | -6.03 | -7.98 | 0.61 | 6.35 | 8.17 | -2.95 | 5.42 | 2.37 | 4.41 | -2.86 |
| Cytoplasm | 12.37 | 4.16 | 17.15 | 3.89 | 14.41 | 7.03 | 11.79 | 7.16 | 2.00 | -5.79 | 13.50 | 2.71 | 16.91 | 4.61 | 13.58 |
| Cytoplasmic Foci | -10.49 | 40.21 | 37.23 | 37.32 | -8.55 | 0.33 | 27.44 | 33.78 | 30.07 | 1.17 | -6.62 | 57.28 | 51.14 | 48.62 | -10.65 |
| Eisosomes | 1.48 | 18.47 | 12.15 | 9.85 | -17.51 | -1.54 | -2.41 | 9.09 | 10.36 | 7.78 | -0.10 | 22.89 | 15.25 | 14.59 | -15.91 |
| Endoplasmic Reticulum | 1.10 | -9.68 | -15.07 | -15.88 | -9.48 | -0.18 | -6.09 | -5.74 | -2.27 | 4.60 | -0.07 | -8.73 | -14.45 | -6.84 | -6.52 |
| Endosome | -8.70 | 10.03 | 7.59 | 13.74 | -4.27 | -9.71 | 1.35 | 1.85 | 10.21 | 0.60 | -12.92 | 13.28 | 7.72 | 17.72 | -5.87 |
| Golgi | -4.84 | 4.42 | 1.70 | 6.02 | -1.53 | -3.80 | 9.22 | -0.70 | 1.18 | -2.03 | -5.83 | 8.87 | 0.51 | 4.38 | -2.54 |
| Lipid Particles | 1.59 | 10.29 | 6.85 | 6.62 | -2.96 | -0.08 | 3.16 | 9.87 | 8.79 | 7.91 | 0.83 | 14.83 | 10.86 | 10.07 | -3.12 |
| Mitochondria | -5.53 | 5.18 | 1.48 | 6.06 | -2.02 | -2.30 | 6.25 | 2.23 | 3.98 | -1.59 | -5.27 | 7.92 | 3.27 | 7.60 | -2.56 |
| Mitotic Spindle | -1.96 | -1.29 | -7.16 | -6.52 | -6.92 | -4.87 | 1.99 | -3.24 | 0.54 | -3.76 | -5.24 | -1.10 | -7.82 | -4.45 | -7.54 |
| None | 2.57 | 2.14 | 2.96 | -0.19 | 3.19 | -1.51 | -0.94 | -2.34 | -1.39 | -1.65 | 1.67 | -0.30 | 0.61 | -1.29 | 1.35 |
| Nuclear Periphery | 0.36 | -7.56 | -15.15 | -14.69 | -12.54 | -0.38 | -11.09 | -11.20 | -11.28 | 3.98 | 0.00 | -11.77 | -18.25 | -18.05 | -12.80 |
| Nuclear Periphery Foci | -1.17 | -7.75 | -2.89 | -2.75 | -1.93 | -1.15 | -6.40 | -7.51 | -7.28 | 3.77 | -1.55 | -10.64 | -4.03 | -3.89 | -1.96 |
| Nucleolus | -1.40 | 5.20 | 3.95 | 3.22 | -3.68 | -3.74 | -0.78 | 2.83 | 6.05 | 2.69 | -2.39 | 6.69 | 4.69 | 4.83 | -3.42 |
| Nucleus | 13.27 | -38.66 | -14.16 | -22.73 | 15.19 | 9.47 | -12.43 | 0.68 | -5.57 | 12.13 | 15.19 | -40.33 | -10.53 | -20.26 | 22.75 |
| Peroxisomes | -9.22 | 8.90 | 7.32 | 10.85 | -2.71 | -4.22 | 8.71 | 6.61 | 9.74 | -1.14 | -9.84 | 12.35 | 9.78 | 14.90 | -3.21 |
| Vacuole | -7.62 | 0.51 | -24.77 | -20.36 | -24.85 | -10.68 | -8.85 | -23.60 | -19.32 | -6.66 | -13.08 | -3.98 | -34.13 | -27.56 | -31.18 |
| Vacuole Periphery | -6.18 | 8.64 | 6.18 | 8.25 | -3.00 | -5.17 | 3.73 | -1.37 | 0.45 | -1.96 | -7.95 | 12.72 | -0.11 | 4.61 | -2.51 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl |
| Localization | |
| Cell Percentages | cytoplasm (22%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | cytoplasm-9 |
Cin1
Cin1
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Cin1-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
