Standard name
Human Ortholog
Description Single-stranded DNA endonuclease (with Rad10p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0.05 0 0 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.09 0.07 0.07 0.06 0.05 0.06 0 0.06 0.06 0.12 0.14 0.14 0.1 0.11 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.19 0.54 0.67 0.51 0.75 0.72 0.72 0.81 0.75 0.79 0.84 0.12 0 0.2 0.05 0 0.08 0 0 0 0 0 0
Nucleus 0.92 0.88 0.77 0.74 0.71 0.67 0.7 0.68 0.63 0.67 0.64 0.65 0.83 0.81 0.72 0.76 0.77 0.77 0.88 0.84 0.79 0.88 0.82 0.56
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.12 0.13 0.13 0 0.09 0.16 0.08 0.14 0.29
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0
Bud 0 0 1 2 3 2 3 6 3 12 4 12 0 0 0 0 0 0 3 1 0 0 0 2
Bud Neck 0 0 0 0 0 1 1 1 0 1 0 0 0 0 0 1 0 0 0 1 0 0 0 0
Bud Site 0 0 0 3 5 9 17 23 14 14 9 23 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 6 4 12 19 21 26 27 28 20 18 20 21 9 17 18 21 21 12 1 0 2 1 0 2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 7 4 0 0 0 0 0 1
Endosome 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 6 2 3 1 2 0 0 0 3
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 0 0
Mitochondria 0 46 145 149 158 259 341 377 251 303 245 314 9 3 26 11 6 11 0 6 2 0 0 4
Nucleus 146 211 207 164 222 234 332 357 197 272 198 245 62 97 94 156 147 105 148 218 219 61 120 102
Nuclear Periphery 0 1 0 0 2 2 1 4 0 4 6 7 0 1 1 0 0 0 1 0 0 0 0 0
Nucleolus 2 2 0 1 4 1 3 9 4 3 3 8 1 1 2 0 1 0 2 1 0 0 3 9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 1 2 1 5 9 1 4 0 3 0 1 0 3 1 1 2 1 6 1 0 0
Vac/Vac Membrane 7 13 4 1 8 3 2 3 2 0 3 2 1 5 11 25 25 18 6 23 44 5 20 53
Unique Cell Count 158 240 268 223 311 347 476 527 311 405 310 376 75 120 131 205 191 136 169 261 279 70 148 182
Labelled Cell Count 161 277 371 342 426 539 732 817 492 631 488 635 82 126 152 235 213 156 169 261 279 70 148 182


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.9 4.7 3.5 3.5 3.6 3.5 3.2 3.3 3.0 3.0 3.1 2.8 4.9 5.1 4.3 6.4 6.8 7.3 4.8 5.5 6.0
Std Deviation (1e-4) 1.0 0.9 0.6 1.1 1.0 1.6 0.9 0.9 1.2 1.0 1.2 1.0 1.0 0.9 0.9 1.5 1.8 2.7 0.7 1.6 1.4
Intensity Change (Log2) – – – -0.01 0.03 -0.01 -0.15 -0.11 -0.25 -0.26 -0.21 -0.35 0.47 0.53 0.28 0.85 0.94 1.05 0.43 0.64 0.77

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 4.8 5.0 4.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.0533 1.5909 1.4033 1.0977 1.1303 1.6071 1.5369 2.7322 2.2105 1.2903 1.5582 2.1541 2.9531 3.3826 3.2057 3.5345 2.4563 3.1055
Actin 0.0397 0 0.0069 0.0037 0.0123 0.0098 0.0262 0.0003 0.0054 0 0.0024 0.0001 0.0095 0 0.0009 0.021 0.0005 0.0045
Bud 0.0006 0 0.0001 0.0008 0.0001 0.0001 0.0002 0.0003 0.0001 0 0.0005 0.0001 0.0004 0 0.0002 0.0003 0 0.0003
Bud Neck 0.0139 0.0002 0.0004 0.003 0.0013 0.0017 0.0008 0.0019 0.0004 0.0002 0.0006 0.0018 0.0013 0.0001 0.001 0.0019 0.0005 0.002
Bud Periphery 0.0013 0 0.0001 0.0025 0.0003 0.0004 0.0004 0.0005 0.0001 0 0.0009 0.0001 0.0013 0 0.0003 0.0005 0 0.0007
Bud Site 0.015 0.0001 0.0002 0.0038 0.0003 0.0002 0.0015 0.0069 0.0002 0.0001 0.0007 0.0001 0.0011 0.0001 0.0069 0.0021 0.0001 0.0002
Cell Periphery 0.0009 0 0 0.0004 0.0001 0.0001 0.0002 0.0003 0.0001 0 0.0001 0 0.0002 0 0.0004 0.0003 0 0.0001
Cytoplasm 0.0059 0.0037 0.0004 0.0004 0.0009 0.002 0.0134 0.0037 0.0196 0.0018 0.0037 0.0059 0.003 0.0023 0.006 0.0019 0.0071 0.0009
Cytoplasmic Foci 0.009 0.0001 0.0008 0.003 0.0022 0.0025 0.0035 0.0003 0.0021 0 0.0039 0.0002 0.0016 0 0.0008 0.0059 0.0001 0.0002
Eisosomes 0.0008 0 0 0.0001 0.0003 0.0001 0.0005 0 0.0001 0 0 0 0.0001 0 0 0.0011 0 0.0001
Endoplasmic Reticulum 0.0049 0.0004 0.0003 0.0001 0.0023 0.0007 0.003 0.0002 0.0022 0 0.0021 0.0012 0.0026 0.0004 0.0008 0.0014 0.0004 0.0002
Endosome 0.0233 0.0013 0.0044 0.0039 0.0115 0.0024 0.0045 0.0005 0.0044 0 0.0371 0.0017 0.009 0.0003 0.0013 0.0476 0.0006 0.0025
Golgi 0.0068 0 0.0018 0.0035 0.0077 0.0022 0.0028 0.0002 0.0009 0 0.0098 0 0.0034 0 0.0002 0.0119 0 0.0013
Lipid Particles 0.0268 0 0.0024 0.0031 0.0149 0.0005 0.0025 0.0002 0.0008 0 0.004 0 0.0025 0 0.0003 0.0122 0 0.0016
Mitochondria 0.0076 0.0002 0.0014 0.0101 0.0394 0.0026 0.0026 0.0006 0.0006 0.0002 0.0073 0.0008 0.0059 0.0001 0.0005 0.0055 0.0003 0.0063
None 0.0109 0.0003 0.0001 0.0001 0.0018 0.0004 0.0609 0.0152 0.0408 0.1651 0.0007 0.0179 0.0144 0.0002 0.0046 0.0019 0.0098 0.0191
Nuclear Periphery 0.0467 0.0214 0.0024 0.0009 0.0191 0.0042 0.0272 0.0081 0.0156 0.0028 0.0145 0.0033 0.0108 0.0084 0.0098 0.0028 0.0141 0.001
Nucleolus 0.008 0.0059 0.0049 0.0094 0.0077 0.0122 0.0066 0.0055 0.0049 0.005 0.0027 0.0134 0.0093 0.0022 0.0072 0.0094 0.0062 0.0091
Nucleus 0.7262 0.9539 0.9709 0.9394 0.8694 0.9522 0.8138 0.9521 0.8969 0.7934 0.8994 0.9352 0.9092 0.9832 0.9523 0.8411 0.9505 0.9448
Peroxisomes 0.0095 0 0.0007 0.0058 0.0022 0.0001 0.0061 0.0002 0.0002 0 0.0013 0 0.0006 0 0.0004 0.0213 0 0.0001
Punctate Nuclear 0.0346 0.0109 0.0013 0.0026 0.0042 0.0043 0.0221 0.0019 0.0039 0.0313 0.0051 0.0159 0.0112 0.0018 0.0034 0.003 0.0092 0.0043
Vacuole 0.004 0.0011 0.0003 0.0028 0.0008 0.0008 0.0006 0.0008 0.0006 0.0001 0.0018 0.0017 0.0016 0.0006 0.0025 0.0051 0.0003 0.0004
Vacuole Periphery 0.0038 0.0003 0.0002 0.0006 0.0011 0.0005 0.0007 0.0001 0.0004 0 0.0014 0.0005 0.001 0.0001 0.0002 0.002 0.0001 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 14.6987 11.9452 18.8357 18.8478 18.8409 15.0244 18.4941 18.8508 21.0628 23.0174
Translational Efficiency 0.3666 0.39 0.2835 0.3045 0.2671 0.3672 0.2483 0.252 0.2353 0.1985

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2284 999 1766 1334 1776 1988 73 1344 4060 2987 1839 2678

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 665.01 781.63 1050.84 848.30 664.17 748.50 1009.81 843.99 664.64 759.58 1049.21 846.14
Standard Deviation 72.51 103.48 128.93 114.20 105.04 100.08 115.46 116.19 88.23 102.43 128.67 115.23
Intensity Change Log 2 — 0.233110 0.660095 0.351199 — 0.172450 0.604459 0.345673 — 0.203118 0.632563 0.348440

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000028 0.000258 0.000280 0.001231 0.000096 0.000186 0.000638 0.001366 0.000058 0.000210 0.000294 0.001298
Bud Neck 0.002153 0.003716 0.005392 0.023174 0.002988 0.007540 0.001963 0.010480 0.002518 0.006261 0.005256 0.016803
Bud Site 0.000555 0.001967 0.002219 0.023373 0.000716 0.004054 0.000459 0.015830 0.000626 0.003356 0.002149 0.019588
Cell Periphery 0.000102 0.000106 0.000070 0.000214 0.000148 0.000147 0.000063 0.000161 0.000122 0.000133 0.000069 0.000188
Cytoplasm 0.062199 0.027423 0.027569 0.084574 0.051852 0.027439 0.004719 0.074730 0.057673 0.027434 0.026662 0.079634
Cytoplasmic Foci 0.005569 0.003891 0.000217 0.007653 0.003735 0.005622 0.000530 0.007994 0.004767 0.005043 0.000229 0.007824
Eisosomes 0.000012 0.000023 0.000011 0.000036 0.000019 0.000020 0.000040 0.000034 0.000015 0.000021 0.000012 0.000035
Endoplasmic Reticulum 0.000774 0.003569 0.003703 0.007229 0.001613 0.003439 0.009665 0.006915 0.001141 0.003482 0.003939 0.007071
Endosome 0.000300 0.000511 0.000310 0.008450 0.000450 0.001988 0.000360 0.009624 0.000366 0.001494 0.000312 0.009039
Golgi 0.000134 0.000169 0.000033 0.004825 0.000305 0.001098 0.000044 0.006557 0.000209 0.000788 0.000033 0.005694
Lipid Particles 0.000617 0.001666 0.000107 0.003246 0.001047 0.001163 0.000594 0.003561 0.000805 0.001331 0.000127 0.003404
Mitochondria 0.000832 0.002364 0.000684 0.008928 0.001378 0.005144 0.000614 0.008955 0.001071 0.004214 0.000681 0.008942
Mitotic Spindle 0.000054 0.003233 0.000227 0.066069 0.000554 0.004698 0.000045 0.039516 0.000272 0.004208 0.000220 0.052743
None 0.011020 0.006938 0.002470 0.012065 0.022023 0.004059 0.001157 0.008669 0.015833 0.005022 0.002418 0.010360
Nuclear Periphery 0.000687 0.000830 0.000679 0.003812 0.001212 0.002136 0.000910 0.003039 0.000917 0.001699 0.000688 0.003424
Nuclear Periphery Foci 0.000275 0.000515 0.000241 0.001049 0.000600 0.001258 0.000782 0.001633 0.000417 0.001009 0.000262 0.001342
Nucleolus 0.005175 0.006951 0.000405 0.002784 0.009125 0.005822 0.002947 0.002859 0.006903 0.006200 0.000506 0.002822
Nucleus 0.907402 0.932817 0.949925 0.699790 0.900430 0.913984 0.967043 0.761408 0.904352 0.920283 0.950605 0.730714
Peroxisomes 0.000462 0.001191 0.000110 0.002417 0.000439 0.002172 0.000221 0.001649 0.000452 0.001844 0.000115 0.002032
Vacuole 0.001573 0.001694 0.005292 0.034259 0.001043 0.006625 0.007121 0.027161 0.001341 0.004976 0.005364 0.030697
Vacuole Periphery 0.000076 0.000167 0.000057 0.004823 0.000226 0.001407 0.000087 0.007860 0.000142 0.000992 0.000058 0.006347

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.60 -17.14 -12.37 -8.55 -8.61 -2.98 -3.86 -3.95 -3.55 0.34 -7.11 -14.31 -7.94 -6.57 -5.41
Bud Neck -2.49 -5.43 -11.59 -9.88 -8.92 -5.58 -0.09 -11.96 -5.27 -9.13 -6.40 -5.47 -15.85 -10.32 -10.82
Bud Site -2.18 -2.77 -8.04 -6.63 -6.70 -4.11 -0.98 -5.73 -3.25 -5.42 -4.75 -2.71 -9.79 -6.64 -7.65
Cell Periphery -0.42 3.38 -3.47 -2.02 -6.48 0.05 2.57 0.97 0.53 -2.12 -0.60 5.61 -1.74 -0.32 -8.08
Cytoplasm 8.63 11.63 -1.48 -8.88 -10.99 6.95 11.37 -2.76 -8.95 -12.70 11.83 13.12 -2.84 -12.97 -14.02
Cytoplasmic Foci 1.61 7.38 3.55 1.51 -5.45 -2.25 5.42 0.31 2.32 -4.04 -0.34 9.55 2.98 3.01 -7.05
Eisosomes -4.89 0.48 -18.19 -9.48 -18.88 -0.30 -3.39 -6.10 -10.70 1.28 -2.82 0.57 -15.04 -15.01 -21.93
Endoplasmic Reticulum -11.86 -16.71 -22.51 -14.62 -13.12 -5.91 -5.11 -17.75 -12.06 1.75 -11.10 -15.59 -28.72 -18.40 -14.10
Endosome -2.26 -0.09 -6.58 -6.02 -6.54 -4.08 -1.23 -6.00 -3.10 -4.78 -4.46 0.25 -8.75 -5.00 -8.71
Golgi -0.64 1.30 -2.08 -2.00 -2.29 -1.87 1.28 -3.01 -1.77 -3.45 -2.16 2.00 -3.67 -2.23 -4.14
Lipid Particles -1.47 7.48 -1.98 0.11 -3.07 -0.66 -0.06 -1.38 -1.08 -1.26 -1.99 5.47 -2.44 -0.73 -4.42
Mitochondria -1.48 0.34 -5.90 -1.93 -6.37 -4.34 1.41 -3.36 0.25 -4.22 -4.82 1.46 -6.11 -0.65 -7.06
Mitotic Spindle -2.20 -2.71 -10.26 -8.76 -10.12 -3.63 0.70 -7.71 -6.08 -7.78 -4.40 -1.27 -12.81 -10.58 -12.69
None 2.72 8.57 2.58 -0.52 -6.72 8.28 9.94 6.87 -2.17 -5.85 9.06 12.32 7.14 -2.52 -7.57
Nuclear Periphery -1.46 -2.95 -11.18 -10.70 -10.69 -2.23 -0.46 -7.57 -4.99 -5.59 -3.20 -0.08 -13.63 -9.31 -14.70
Nuclear Periphery Foci -1.57 -0.27 -4.90 -2.75 -4.42 -2.18 -1.13 -2.62 0.18 0.78 -2.70 -0.31 -5.13 -0.69 -4.04
Nucleolus -0.77 6.37 3.05 3.29 -5.73 2.22 4.61 4.79 3.14 -0.34 0.95 9.63 5.54 4.59 -6.45
Nucleus -3.53 -9.06 17.74 18.76 23.77 -1.76 -3.14 11.69 13.24 9.66 -2.99 -11.40 20.92 22.19 29.29
Peroxisomes -2.30 3.16 -0.92 1.66 -3.05 -3.40 0.68 -0.81 2.73 -1.22 -3.97 3.75 -1.18 3.18 -3.53
Vacuole -0.61 -7.37 -16.32 -16.32 -14.12 -6.44 -2.68 -14.72 -12.34 -4.14 -5.91 -8.53 -21.88 -19.82 -17.65
Vacuole Periphery -4.21 1.14 -3.05 -2.84 -3.08 -3.69 1.12 -3.12 -1.77 -3.23 -4.07 2.25 -4.20 -2.41 -4.36
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Single-stranded DNA endonuclease (with Rad10p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Rad1

Rad1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rad1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available