| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Subunit of the HDA1 histone deacetylase complex; possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex contains Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; relocalizes to the cytosol in response to hypoxia; similar to Hda2p |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 1 | 0 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| Bud | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 1 | 0 | 0 | 1 | 0 | 0 |
| Bud Neck | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 0 | 0 | 0 | 0 | 1 | 1 |
| Bud Site | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | – | – | – | – | – | – |
| Cell Periphery | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 1 | 0 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| Cytoplasm | 0 | 4 | – | – | – | – | – | – | – | – | – | – | 15 | 55 | 79 | – | – | – | 0 | 1 | 0 | 1 | 6 | 6 |
| Endoplasmic Reticulum | 2 | 0 | – | – | – | – | – | – | – | – | – | – | 1 | 0 | 0 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| Endosome | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 1 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| Golgi | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| Mitochondria | 33 | 7 | – | – | – | – | – | – | – | – | – | – | 1 | 1 | 0 | – | – | – | 0 | 1 | 0 | 0 | 1 | 1 |
| Nucleus | 131 | 88 | – | – | – | – | – | – | – | – | – | – | 233 | 376 | 435 | – | – | – | 125 | 107 | 0 | 96 | 285 | 285 |
| Nuclear Periphery | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 1 | 0 | 3 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| Nucleolus | 8 | 4 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 2 | – | – | – | 5 | 1 | 0 | 1 | 7 | 7 |
| Peroxisomes | 0 | 1 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| SpindlePole | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 2 | 8 | 9 | – | – | – | 0 | 0 | 0 | 0 | 1 | 1 |
| Vac/Vac Membrane | 1 | 1 | – | – | – | – | – | – | – | – | – | – | 0 | 3 | 3 | – | – | – | 3 | 3 | 0 | 6 | 17 | 17 |
| Unique Cell Count | 142 | 98 | 250 | 435 | 520 | 139 | 119 | 1 | 113 | 330 | 330 | |||||||||||||
| Labelled Cell Count | 175 | 105 | 253 | 445 | 532 | 139 | 119 | 1 | 113 | 330 | 330 | |||||||||||||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 5.3 | 6.1 | – | – | – | – | – | – | – | – | – | – | 7.3 | 7.5 | 7.0 | – | – | – | 5.8 | 6.5 | 6.5 |
| Std Deviation (1e-4) | 1.0 | 1.3 | – | – | – | – | – | – | – | – | – | – | 1.2 | 1.5 | 1.5 | – | – | – | 1.1 | 1.0 | 1.0 |
| Intensity Change (Log2) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | 0.9995 | 1.0769 | 0.8571 | 0.3879 | 0.9876 | 0.6086 | 1.5035 | 1.5598 | 1.6772 | 1.1364 | 1.3104 | 1.197 | 0.182 | 0.3343 | -0.0803 | 0.3648 | -0.1162 | -0.091 |
| Actin | 0.0233 | 0 | 0.0306 | 0.0111 | 0.0336 | 0.0019 | 0.0115 | 0 | 0.0001 | 0 | 0.0001 | 0.0008 | 0.007 | 0 | 0.0047 | 0.0034 | 0.0145 | 0.0037 |
| Bud | 0.0014 | 0 | 0.0002 | 0.0002 | 0.0005 | 0.0001 | 0.0007 | 0 | 0.0002 | 0.001 | 0 | 0 | 0.0001 | 0 | 0.0001 | 0.0001 | 0.0002 | 0 |
| Bud Neck | 0.0018 | 0.0002 | 0.0015 | 0.0008 | 0.0007 | 0.0041 | 0.0032 | 0.0001 | 0.0001 | 0.0002 | 0.0003 | 0.0008 | 0.0014 | 0 | 0.0005 | 0.0002 | 0.0006 | 0.0008 |
| Bud Periphery | 0.002 | 0 | 0.0003 | 0.0002 | 0.0006 | 0.0003 | 0.0017 | 0 | 0.0001 | 0.0002 | 0.0001 | 0 | 0.0002 | 0 | 0.0002 | 0.0001 | 0.0003 | 0.0001 |
| Bud Site | 0.0056 | 0.0002 | 0.0027 | 0.0009 | 0.0023 | 0.0002 | 0.0029 | 0.0001 | 0.0002 | 0.0001 | 0.0001 | 0.0002 | 0.0009 | 0 | 0.0007 | 0.0003 | 0.0011 | 0 |
| Cell Periphery | 0.0004 | 0 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0007 | 0 | 0 | 0 | 0 | 0 | 0.0001 | 0 | 0.0001 | 0.0001 | 0.0001 | 0 |
| Cytoplasm | 0.0073 | 0.002 | 0.0104 | 0.0014 | 0.0002 | 0.0003 | 0.008 | 0.002 | 0.0008 | 0.0012 | 0.0009 | 0.0001 | 0.0015 | 0 | 0.0013 | 0.0068 | 0.0011 | 0.0002 |
| Cytoplasmic Foci | 0.0131 | 0.0002 | 0.0103 | 0.019 | 0.0127 | 0.0004 | 0.0251 | 0.0001 | 0.0023 | 0.0023 | 0.002 | 0.0044 | 0.0071 | 0 | 0.0048 | 0.0082 | 0.004 | 0.0001 |
| Eisosomes | 0.0001 | 0 | 0.0004 | 0.0001 | 0.0002 | 0 | 0.0002 | 0 | 0 | 0 | 0 | 0 | 0.0001 | 0 | 0.0002 | 0.0001 | 0.0001 | 0 |
| Endoplasmic Reticulum | 0.0025 | 0.0007 | 0.0029 | 0.0004 | 0.0002 | 0.0003 | 0.0031 | 0.0001 | 0.0001 | 0 | 0.0001 | 0 | 0.0005 | 0 | 0.001 | 0.0103 | 0.0013 | 0.0001 |
| Endosome | 0.0114 | 0.0007 | 0.0069 | 0.0197 | 0.0249 | 0.0054 | 0.0176 | 0.0002 | 0.0052 | 0 | 0.0313 | 0.0013 | 0.0072 | 0 | 0.013 | 0.0173 | 0.0079 | 0.0003 |
| Golgi | 0.0045 | 0 | 0.006 | 0.0251 | 0.0331 | 0.0035 | 0.006 | 0 | 0.0025 | 0 | 0.0056 | 0.0019 | 0.0018 | 0 | 0.0022 | 0.0026 | 0.0024 | 0.0009 |
| Lipid Particles | 0.0088 | 0.0002 | 0.0027 | 0.0103 | 0.0643 | 0.0025 | 0.0141 | 0 | 0.0052 | 0 | 0.0104 | 0.0034 | 0.0063 | 0 | 0.0043 | 0.0152 | 0.0113 | 0.0003 |
| Mitochondria | 0.0176 | 0.0003 | 0.006 | 0.0041 | 0.0549 | 0.0024 | 0.0104 | 0.0002 | 0.0017 | 0.0003 | 0.0026 | 0.001 | 0.0081 | 0 | 0.0014 | 0.0053 | 0.0013 | 0.0004 |
| None | 0.0096 | 0.0033 | 0.0122 | 0.0024 | 0.0001 | 0.0002 | 0.0037 | 0.0119 | 0.0004 | 0.0009 | 0.0014 | 0 | 0.0018 | 0 | 0.0072 | 0.0078 | 0.0012 | 0.0001 |
| Nuclear Periphery | 0.0112 | 0.0066 | 0.0051 | 0.0019 | 0.0023 | 0.001 | 0.0202 | 0.0035 | 0.0013 | 0.0005 | 0.0077 | 0.0002 | 0.0018 | 0.0002 | 0.0035 | 0.0136 | 0.0066 | 0.0005 |
| Nucleolus | 0.0165 | 0.0161 | 0.0084 | 0.0071 | 0.0138 | 0.0547 | 0.0179 | 0.0141 | 0.0185 | 0.0176 | 0.0351 | 0.0242 | 0.0126 | 0.0077 | 0.0104 | 0.005 | 0.0377 | 0.0231 |
| Nucleus | 0.8234 | 0.9666 | 0.8853 | 0.8798 | 0.7312 | 0.9202 | 0.8135 | 0.9553 | 0.9283 | 0.9545 | 0.8904 | 0.9392 | 0.9256 | 0.9913 | 0.9333 | 0.8583 | 0.8912 | 0.965 |
| Peroxisomes | 0.0112 | 0 | 0.0046 | 0.0077 | 0.0186 | 0.0002 | 0.0134 | 0 | 0.0013 | 0 | 0.001 | 0.005 | 0.007 | 0 | 0.0019 | 0.0408 | 0.0019 | 0.0001 |
| Punctate Nuclear | 0.0198 | 0.0022 | 0.0025 | 0.0068 | 0.0026 | 0.0014 | 0.0172 | 0.012 | 0.0312 | 0.0208 | 0.0081 | 0.0172 | 0.0077 | 0.0006 | 0.008 | 0.0014 | 0.0139 | 0.0041 |
| Vacuole | 0.0062 | 0.0003 | 0.0004 | 0.0006 | 0.0017 | 0.0004 | 0.0041 | 0.0002 | 0.0003 | 0.0001 | 0.0018 | 0.0001 | 0.0007 | 0 | 0.0008 | 0.0021 | 0.0007 | 0.0001 |
| Vacuole Periphery | 0.0023 | 0.0002 | 0.0003 | 0.0003 | 0.0012 | 0.0004 | 0.0048 | 0.0001 | 0.0002 | 0 | 0.001 | 0 | 0.0004 | 0 | 0.0003 | 0.0009 | 0.0005 | 0 |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 6.7281 | 8.0193 | 5.2068 | 11.2077 | 11.9945 | 10.6469 | 9.5019 | 12.1423 | 10.4446 | 11.655 |
| Translational Efficiency | 1.4044 | 0.848 | 1.3529 | 0.6672 | 0.5927 | 0.8296 | 0.8242 | 0.7512 | 0.7347 | 0.5654 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | ✘ |
| Protein Localization | ✘ |
| Gene Expression | ✘ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 118 | 1378 | 1782 | 790 | 1663 | 1276 | 1488 | 181 | 1781 | 2654 | 3270 | 971 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 656.41 | 766.96 | 852.60 | 950.81 | 699.65 | 759.72 | 895.84 | 948.66 | 696.79 | 763.48 | 872.28 | 950.41 |
| Standard Deviation | 64.88 | 124.91 | 129.63 | 146.39 | 98.37 | 111.60 | 144.19 | 137.25 | 97.11 | 118.75 | 138.14 | 144.73 |
| Intensity Change Log 2 | — | 0.224554 | 0.377272 | 0.534560 | — | 0.118834 | 0.356608 | 0.439258 | — | 0.170977 | 0.366647 | 0.486176 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000052 | 0.000357 | 0.000457 | 0.001161 | 0.000159 | 0.000395 | 0.000584 | 0.001233 | 0.000152 | 0.000375 | 0.000515 | 0.001175 |
| Bud Neck | 0.001184 | 0.005472 | 0.030580 | 0.027513 | 0.003158 | 0.005771 | 0.019788 | 0.010569 | 0.003027 | 0.005616 | 0.025669 | 0.024355 |
| Bud Site | 0.000296 | 0.000879 | 0.003399 | 0.014995 | 0.000564 | 0.000790 | 0.002102 | 0.004929 | 0.000546 | 0.000836 | 0.002809 | 0.013119 |
| Cell Periphery | 0.000243 | 0.000080 | 0.000328 | 0.000159 | 0.000097 | 0.000090 | 0.000168 | 0.000155 | 0.000107 | 0.000085 | 0.000255 | 0.000159 |
| Cytoplasm | 0.024067 | 0.004857 | 0.026136 | 0.009988 | 0.011002 | 0.007814 | 0.014846 | 0.011381 | 0.011867 | 0.006279 | 0.020998 | 0.010247 |
| Cytoplasmic Foci | 0.002856 | 0.000505 | 0.001455 | 0.002033 | 0.001694 | 0.002487 | 0.001088 | 0.000106 | 0.001771 | 0.001458 | 0.001288 | 0.001674 |
| Eisosomes | 0.000021 | 0.000018 | 0.000071 | 0.000029 | 0.000014 | 0.000026 | 0.000028 | 0.000030 | 0.000015 | 0.000022 | 0.000051 | 0.000029 |
| Endoplasmic Reticulum | 0.001069 | 0.003905 | 0.003297 | 0.005786 | 0.002632 | 0.004503 | 0.003549 | 0.005086 | 0.002528 | 0.004193 | 0.003412 | 0.005655 |
| Endosome | 0.000208 | 0.000365 | 0.000551 | 0.004938 | 0.000273 | 0.002255 | 0.001285 | 0.000301 | 0.000268 | 0.001274 | 0.000885 | 0.004074 |
| Golgi | 0.000038 | 0.000253 | 0.000090 | 0.002708 | 0.000169 | 0.001083 | 0.000327 | 0.000091 | 0.000160 | 0.000652 | 0.000198 | 0.002220 |
| Lipid Particles | 0.000563 | 0.000289 | 0.000249 | 0.000473 | 0.000856 | 0.000858 | 0.000248 | 0.000173 | 0.000837 | 0.000562 | 0.000248 | 0.000417 |
| Mitochondria | 0.000388 | 0.001321 | 0.001680 | 0.005707 | 0.001432 | 0.004265 | 0.001961 | 0.001462 | 0.001363 | 0.002737 | 0.001808 | 0.004916 |
| Mitotic Spindle | 0.000025 | 0.000758 | 0.007076 | 0.027661 | 0.003475 | 0.005774 | 0.012247 | 0.013276 | 0.003247 | 0.003170 | 0.009429 | 0.024979 |
| None | 0.012160 | 0.006763 | 0.014992 | 0.005678 | 0.009418 | 0.005794 | 0.013551 | 0.011589 | 0.009599 | 0.006297 | 0.014336 | 0.006780 |
| Nuclear Periphery | 0.000533 | 0.000499 | 0.001095 | 0.002275 | 0.001010 | 0.001816 | 0.000848 | 0.000574 | 0.000978 | 0.001132 | 0.000983 | 0.001958 |
| Nuclear Periphery Foci | 0.000062 | 0.000278 | 0.000174 | 0.001124 | 0.000261 | 0.000673 | 0.000256 | 0.000101 | 0.000247 | 0.000468 | 0.000211 | 0.000934 |
| Nucleolus | 0.007469 | 0.014535 | 0.010402 | 0.006284 | 0.013371 | 0.017522 | 0.009446 | 0.006117 | 0.012980 | 0.015971 | 0.009967 | 0.006253 |
| Nucleus | 0.948020* | 0.956186* | 0.894607* | 0.867916* | 0.949434* | 0.929831* | 0.914219* | 0.929444* | 0.949341* | 0.943515* | 0.903531* | 0.879386* |
| Peroxisomes | 0.000269 | 0.000462 | 0.000143 | 0.000392 | 0.000368 | 0.001060 | 0.000247 | 0.000301 | 0.000362 | 0.000750 | 0.000191 | 0.000375 |
| Vacuole | 0.000401 | 0.001612 | 0.002159 | 0.009670 | 0.000441 | 0.004712 | 0.002606 | 0.002943 | 0.000439 | 0.003102 | 0.002362 | 0.008416 |
| Vacuole Periphery | 0.000076 | 0.000605 | 0.001060 | 0.003507 | 0.000171 | 0.002483 | 0.000606 | 0.000140 | 0.000165 | 0.001508 | 0.000853 | 0.002879 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -10.15 | -12.68 | -18.22 | -13.84 | -10.55 | -7.98 | -18.15 | -7.93 | -6.85 | -5.20 | -8.95 | -16.84 | -18.30 | -15.42 | -11.50 |
| Bud Neck | -5.88 | -20.21 | -14.13 | -11.65 | 1.37 | -4.13 | -16.52 | -9.64 | -6.54 | 4.39 | -5.15 | -24.72 | -14.46 | -12.45 | 0.88 |
| Bud Site | -1.82 | -5.22 | -4.89 | -4.49 | -2.92 | -1.42 | -6.68 | -3.88 | -3.64 | -2.29 | -1.30 | -6.24 | -5.26 | -5.04 | -3.49 |
| Cell Periphery | 1.31 | -0.24 | 0.70 | -5.45 | 3.92 | 0.38 | -2.19 | -2.03 | -2.36 | -0.38 | 1.41 | -4.79 | -2.75 | -5.89 | 3.03 |
| Cytoplasm | 2.53 | 0.39 | 1.95 | -3.29 | 6.09 | 1.45 | -0.51 | 0.42 | -0.65 | 0.81 | 3.45 | -2.99 | 1.46 | -2.41 | 5.27 |
| Cytoplasmic Foci | 2.04 | 1.52 | 1.77 | -0.70 | 0.90 | -0.65 | 2.43 | 3.70 | 4.60 | 2.53 | 1.15 | 2.36 | 2.66 | 2.24 | 0.93 |
| Eisosomes | 1.05 | -3.98 | -7.05 | -11.41 | 1.53 | -6.23 | -11.43 | -6.95 | -4.87 | -3.69 | -5.06 | -6.19 | -14.13 | -11.23 | 0.15 |
| Endoplasmic Reticulum | -8.82 | -9.36 | -13.96 | -7.96 | -8.62 | -5.87 | -8.05 | -6.13 | -3.98 | -4.06 | -7.03 | -7.83 | -12.83 | -8.67 | -9.27 |
| Endosome | -1.57 | -3.84 | -2.36 | -2.17 | -1.95 | -3.69 | -2.23 | -3.44 | 2.90 | 0.83 | -3.79 | -3.10 | -2.40 | -0.81 | -1.68 |
| Golgi | -2.12 | -7.31 | -1.60 | -1.23 | -1.49 | -2.61 | -0.90 | -0.86 | 2.45 | 0.29 | -2.68 | -0.15 | -1.41 | -0.46 | -1.40 |
| Lipid Particles | 1.63 | 1.88 | 0.98 | -1.41 | -2.12 | 0.24 | 1.56 | 1.18 | 2.57 | -1.04 | 1.01 | 1.78 | 1.37 | 1.54 | -1.72 |
| Mitochondria | -2.78 | -8.37 | -3.50 | -2.53 | -2.12 | -2.92 | -1.62 | -1.92 | 2.04 | -0.46 | -2.42 | -1.72 | -2.60 | -1.02 | -2.05 |
| Mitotic Spindle | -1.12 | -5.62 | -6.13 | -5.90 | -3.66 | -1.30 | -3.99 | -2.69 | -2.36 | -1.44 | -0.04 | -4.61 | -5.81 | -5.90 | -3.71 |
| None | 1.53 | 0.18 | 2.04 | 1.65 | 5.04 | 2.15 | -0.03 | 1.09 | -0.57 | 1.10 | 2.41 | -0.81 | 3.44 | 1.21 | 5.26 |
| Nuclear Periphery | 0.53 | -3.68 | -9.03 | -9.63 | -6.02 | -2.00 | -1.01 | -2.55 | 0.55 | -2.12 | -0.89 | -1.23 | -6.68 | -4.56 | -6.70 |
| Nuclear Periphery Foci | -3.77 | -2.66 | -3.72 | -2.46 | -2.94 | -3.21 | -0.39 | -1.20 | 0.16 | -1.06 | -2.85 | 0.09 | -2.89 | -1.40 | -2.93 |
| Nucleolus | -5.00 | -3.36 | 1.67 | 8.23 | 6.59 | -3.28 | 2.87 | 3.69 | 5.94 | 1.60 | -2.99 | 1.95 | 6.92 | 11.10 | 6.41 |
| Nucleus | -0.87 | 4.28 | 5.23 | 10.57 | 2.31 | 3.80 | 6.92 | 4.39 | 2.61 | 1.60 | 1.56 | 10.79 | 9.98 | 9.32 | 3.52 |
| Peroxisomes | -1.44 | 1.26 | -0.22 | 1.51 | -3.07 | -2.36 | 2.10 | -0.02 | 2.15 | -1.41 | -2.04 | 2.83 | 1.33 | 3.16 | -2.53 |
| Vacuole | -1.52 | -4.24 | -7.45 | -6.66 | -6.56 | -4.13 | -6.56 | -3.76 | -2.87 | -3.06 | -4.40 | -8.47 | -8.42 | -6.68 | -6.95 |
| Vacuole Periphery | -1.89 | -2.45 | -1.91 | -1.04 | -0.62 | -3.23 | -1.60 | -0.47 | 3.20 | 1.50 | -3.57 | -2.59 | -1.78 | 0.52 | -0.80 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Subunit of the HDA1 histone deacetylase complex; possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex contains Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; relocalizes to the cytosol in response to hypoxia; similar to Hda2p |
| Localization | |
| Cell Percentages | nucleus (96%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | nucleus-4 |
Hda3
Hda3
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Hda3-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
