Standard name
Human Ortholog
Description Tetra-spanning membrane protein found mostly in the late Golgi; non-essential; can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0.05 0.06 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0.05 0.05 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.22 0.27 0.23 0.36 0.43 0.5 0.53 0.44 0.45 0.46 0.43 0.44 0.2 0.25 0.28 0.3 0.18 0.28 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.07 0.1 0 0 0 0 0 0 0 0.06 0.08 0.09 0.11 0.05 0 0 0 0 0 0 0 0 0.06
Endosome 0 0.06 0.12 0.23 0.18 0.08 0.05 0.05 0.07 0.12 0.05 0 0.1 0.09 0.11 0.11 0.12 0.1 0.19 0.23 0.31 0.21 0.22 0.19
Golgi 0.13 0.1 0.1 0.1 0.05 0 0 0 0 0 0 0 0.18 0.18 0.17 0.1 0.09 0.14 0.15 0.12 0.18 0.19 0.21 0.18
Mitochondria 0 0.07 0.2 0.21 0.19 0.37 0.36 0.42 0.44 0.32 0.46 0.5 0 0 0 0 0.07 0 0 0 0 0.06 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.77 0.63 0.48 0.28 0.29 0.17 0.17 0.16 0.12 0.16 0.11 0.11 0.52 0.5 0.58 0.64 0.69 0.61 0.63 0.56 0.42 0.44 0.42 0.47
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 9 5 5 2 0 6 2 2 10 6 5 13 7 3 1 10 13 17 0 2 2 1 0 1
Bud 0 2 1 2 2 8 9 15 22 22 13 17 0 0 0 0 1 0 0 2 0 1 1 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 1 0 3 1 5 9 1 8 4 0 0 0 0 2 2 0 0 0 0 0 0
Cytoplasm 80 81 63 79 123 156 239 184 191 192 131 139 26 37 42 79 48 81 1 6 4 1 4 8
Endoplasmic Reticulum 8 21 27 8 11 14 14 9 8 18 17 26 12 16 7 6 12 12 2 2 4 4 5 14
Endosome 6 18 33 50 52 25 23 21 30 52 14 6 13 14 16 30 32 30 73 79 104 33 40 46
Golgi 46 29 26 23 13 3 1 4 4 4 2 6 23 27 25 25 25 40 57 42 59 30 38 44
Mitochondria 13 21 54 46 53 117 163 176 185 135 138 156 4 3 0 10 19 9 6 11 12 9 7 7
Nucleus 1 0 1 0 1 1 3 3 3 0 0 1 1 0 2 0 0 1 0 0 0 1 2 1
Nuclear Periphery 2 2 2 2 0 0 0 2 0 0 1 2 0 0 0 0 4 0 2 0 2 1 0 1
Nucleolus 3 3 1 0 1 1 4 4 0 2 2 2 0 0 0 2 3 2 0 0 0 1 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 1 2 0 2 0 1 6 1 1 1 0 0 1 0 0 0 0 1 0 0 0
Vac/Vac Membrane 278 189 128 62 83 52 74 68 49 66 33 34 67 75 88 169 186 180 245 194 140 69 77 117
Unique Cell Count 361 300 269 222 286 314 448 419 420 420 302 315 129 151 151 263 269 293 391 345 333 158 185 251
Labelled Cell Count 446 371 342 276 341 386 535 493 514 504 366 407 154 175 181 332 345 374 391 345 333 158 185 251


Early Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 12.5 10.9 8.6 7.8 7.4 6.8 6.3 6.4 6.5 6.3 6.4 6.6 10.7 10.2 10.8 11.2 10.9 12.1 11.7 11.4 12.0
Std Deviation (1e-4) 2.3 2.3 1.7 1.5 1.6 1.5 1.3 1.3 1.4 1.4 1.4 1.4 2.2 1.7 2.4 2.6 2.9 2.7 2.3 2.1 2.5
Intensity Change (Log2) – – – -0.14 -0.23 -0.35 -0.45 -0.43 -0.42 -0.46 -0.42 -0.39 0.31 0.24 0.33 0.37 0.34 0.49 0.44 0.41 0.48

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0.5 0 0 1.6 0 0 0 1.4 1.9 2.4
Bud 0 0 0 0 2.7 3.5 3.5 3.0 3.5 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3.0 4.9 6.5 7.9 5.5 5.9 5.9 5.0 5.2 -0.7 0.3 1.0 1.7 -1.6 1.1
Endoplasmic Reticulum -2.8 -2.9 -2.6 -3.9 -4.5 -4.7 -3.0 -2.0 -0.7 -0.2 0.2 -1.9 -3.7 -2.5 -2.8
Endosome 3.0 1.9 -1.7 -3.4 -3.5 -2.3 0 -3.3 -5.0 -0.6 -0.9 -0.5 -0.3 -0.1 -0.8
Golgi 0.3 -2.4 -4.8 -6.4 -5.5 -5.5 -5.5 -5.0 -4.1 2.3 2.4 2.1 -0.1 -0.1 1.5
Mitochondria 0.2 -0.5 4.5 4.6 6.0 6.4 3.5 6.5 7.4 -4.5 -5.2 -5.9 -5.8 -4.4 -6.4
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -4.5 -4.5 -8.1 -9.0 -8.9 -10.5 -9.1 -9.7 -9.9 0.8 0.4 2.1 3.9 5.1 3.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 11.7272 14.525 13.2093 13.0209 12.6816 12.7695 12.2343 15.9026 13.5484 15.6094 13.1377 14.028 8.2088 11.6296 10.0373 9.9733 9.6249 10.2625
Actin 0.0001 0.0002 0.0001 0 0.0001 0.0001 0.0003 0.0013 0.0001 0 0.0001 0.0001 0.0003 0.0002 0.0049 0 0 0.0006
Bud 0.0001 0.0001 0.0002 0.0001 0 0.0001 0.0001 0.0005 0.0008 0 0 0.0001 0.0002 0.0002 0.0002 0.0001 0.0001 0.0001
Bud Neck 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0001 0.0002 0.0001 0 0 0.0001 0.0001 0.0001 0.0007 0.0001 0 0.0002
Bud Periphery 0.0001 0.0001 0.0002 0.0001 0 0.0001 0.0001 0.0003 0.0011 0 0 0.0001 0.0002 0.0001 0.0002 0.0002 0 0.0001
Bud Site 0.0001 0.0001 0.0001 0 0 0.0001 0.0001 0.0007 0.0004 0 0 0 0.0001 0.0002 0.0057 0 0 0.0001
Cell Periphery 0.0001 0.0001 0.0001 0 0 0 0 0.0001 0 0 0 0 0.0001 0 0.0003 0.0001 0 0
Cytoplasm 0.0146 0.0266 0.0117 0.0025 0.0098 0.0108 0.0055 0.0155 0.008 0.0011 0.0028 0.0045 0.0067 0.0149 0.0082 0.0025 0.0045 0.0051
Cytoplasmic Foci 0.0245 0.0266 0.0206 0.0121 0.0168 0.0253 0.0217 0.0299 0.0259 0.0109 0.0177 0.0212 0.0195 0.0288 0.0292 0.005 0.0098 0.0138
Eisosomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0049 0.0057 0.0042 0.0014 0.0081 0.0057 0.0027 0.0042 0.0034 0.0006 0.0013 0.003 0.0036 0.0029 0.0027 0.0016 0.0023 0.0037
Endosome 0.6613 0.5953 0.5787 0.5709 0.5911 0.6015 0.6095 0.6 0.5999 0.6008 0.6223 0.5425 0.6197 0.6097 0.6077 0.5052 0.6899 0.6065
Golgi 0.1261 0.1655 0.1438 0.1037 0.1037 0.1897 0.2537 0.2357 0.2681 0.1637 0.2846 0.3388 0.1805 0.181 0.1557 0.0827 0.0603 0.2056
Lipid Particles 0.0013 0.0018 0.0015 0.0006 0.0006 0.0004 0.0022 0.0003 0.0003 0.0001 0.0004 0.0006 0.0018 0.0005 0.0017 0.0002 0.0006 0.0018
Mitochondria 0.0078 0.0038 0.0055 0.0016 0.001 0.0068 0.0127 0.0032 0.0072 0.0005 0.0055 0.0083 0.0148 0.0045 0.0101 0.0047 0.0034 0.0049
None 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0001 0.0001 0 0 0 0 0.0001 0.0001 0.0007 0 0.0001 0.0003
Nuclear Periphery 0.0034 0.0056 0.0033 0.0026 0.0034 0.0029 0.0023 0.0019 0.0012 0.0007 0.0006 0.0014 0.0035 0.0022 0.0025 0.003 0.0023 0.0044
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0.0001 0 0.0007 0 0 0.0002
Nucleus 0.0002 0.0003 0.0003 0.0002 0.0002 0.0002 0.0002 0.0002 0.0001 0 0 0.0001 0.0004 0.0002 0.0032 0.0002 0.0001 0.0003
Peroxisomes 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0002 0.0002 0.0003 0 0.0001 0 0.0003 0.0002 0.0005 0 0 0.0003
Punctate Nuclear 0 0 0 0 0 0 0 0 0 0 0 0 0.0001 0 0.0011 0 0 0.0008
Vacuole 0.0701 0.088 0.1107 0.126 0.1098 0.0614 0.0377 0.0423 0.0338 0.0665 0.0183 0.0227 0.0701 0.0621 0.0757 0.1566 0.0872 0.0505
Vacuole Periphery 0.085 0.0798 0.1189 0.1781 0.1548 0.0945 0.0508 0.0634 0.0491 0.1551 0.0461 0.0566 0.0778 0.092 0.0883 0.2376 0.1394 0.1008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 68.1114 85.2424 65.5126 68.6116 68.4398 64.67 75.0302 85.699 88.3839 74.505
Translational Efficiency 0.9341 0.7047 1.0134 0.8669 0.9483 1.3202 0.914 1.0064 0.9849 0.7921

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
6 17 2083 6 1734 23 1422 1447 1740 40 3505 1453

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 996.77 392.61 1245.56 1049.82 894.34 307.04 1151.97 972.01 894.69 343.41 1207.59 972.33
Standard Deviation 87.49 253.99 205.33 85.91 131.88 5.12 161.14 127.95 131.89 170.94 194.17 127.90
Intensity Change Log 2 — -1.344164 0.321462 0.074809 — -1.542397 0.365208 0.120148 — -1.434528 0.342316 0.096428

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.009917 0.000057 0.000145 0.000070 0.000088 0.000058 0.000950 0.000651 0.000121 0.000057 0.000471 0.000649
Bud Neck 0.001992 0.000032 0.000257 0.001208 0.000241 0.000027 0.000124 0.006055 0.000247 0.000029 0.000203 0.006035
Bud Site 0.038064 0.000103 0.003900 0.039059 0.004689 0.000051 0.003260 0.017323 0.004804 0.000073 0.003640 0.017413
Cell Periphery 0.000078 0.000120 0.000131 0.000063 0.000136 0.000088 0.000119 0.000030 0.000135 0.000102 0.000126 0.000030
Cytoplasm 0.033196 0.000114 0.005439 0.039222 0.007001 0.000083 0.002156 0.075649 0.007091 0.000096 0.004107 0.075499
Cytoplasmic Foci 0.059239 0.001588 0.041861 0.209068 0.164690 0.000030 0.072821 0.279401 0.164326 0.000692 0.054421 0.279111
Eisosomes 0.000021 0.000079 0.000007 0.000019 0.000018 0.000064 0.000012 0.000025 0.000018 0.000070 0.000009 0.000025
Endoplasmic Reticulum 0.000137 0.000008 0.001061 0.000604 0.000995 0.000001 0.000983 0.000428 0.000992 0.000004 0.001029 0.000429
Endosome 0.233673 0.004751 0.071221 0.197042 0.137623 0.000003 0.094748 0.218651 0.137954 0.002021 0.080766 0.218561
Golgi 0.077907 0.040217 0.488738 0.224509 0.378813 0.000008 0.685037 0.051986 0.377776 0.017097 0.568378 0.052699
Lipid Particles 0.000178 0.000081 0.000842 0.001121 0.000715 0.000056 0.001303 0.002614 0.000713 0.000067 0.001029 0.002608
Mitochondria 0.002662 0.000023 0.004050 0.000857 0.022051 0.000013 0.001958 0.003264 0.021984 0.000017 0.003201 0.003254
Mitotic Spindle 0.000406 0.000437 0.005644 0.004008 0.001251 0.000478 0.000591 0.017425 0.001248 0.000461 0.003594 0.017370
None 0.000020 0.939996 0.000104 0.000016 0.000154 0.998672 0.000026 0.000104 0.000153 0.973735 0.000072 0.000104
Nuclear Periphery 0.000012 0.000006 0.000551 0.000109 0.000055 0.000001 0.000074 0.000268 0.000055 0.000003 0.000358 0.000268
Nuclear Periphery Foci 0.000026 0.000083 0.001844 0.003046 0.000297 0.000131 0.000657 0.000459 0.000296 0.000110 0.001363 0.000470
Nucleolus 0.000009 0.000047 0.000033 0.000050 0.000066 0.000087 0.000005 0.000247 0.000065 0.000070 0.000022 0.000246
Nucleus 0.000026 0.000022 0.000085 0.001323 0.000116 0.000018 0.000013 0.002405 0.000116 0.000020 0.000056 0.002401
Peroxisomes 0.246340 0.000124 0.000101 0.001307 0.000401 0.000124 0.000125 0.012749 0.001249 0.000124 0.000111 0.012702
Vacuole 0.087377 0.006633 0.172631 0.214898 0.069518 0.000004 0.061835 0.293059 0.069580 0.002821 0.127681 0.292736
Vacuole Periphery 0.208719 0.005480 0.201354 0.062403 0.211084 0.000000 0.073202 0.017204 0.211076 0.002329 0.149362 0.017391

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin NaN NaN NaN NaN NaN 0.90 -1.32 -4.96 -5.21 0.48 1.63 -1.31 -4.51 -5.27 -0.54
Bud Neck NaN NaN NaN NaN NaN 5.73 2.48 -13.37 -13.85 -13.62 5.97 0.88 -13.37 -13.86 -13.46
Bud Site NaN NaN NaN NaN NaN 12.77 1.92 -9.23 -13.34 -9.61 12.79 2.03 -9.20 -13.39 -10.01
Cell Periphery NaN NaN NaN NaN NaN 1.27 0.70 5.73 1.78 6.66 0.94 0.33 5.73 2.33 7.61
Cytoplasm NaN NaN NaN NaN NaN 9.57 5.15 -20.68 -22.70 -21.95 9.66 3.02 -20.68 -22.73 -21.48
Cytoplasmic Foci NaN NaN NaN NaN NaN 49.51 23.57 -15.03 -49.70 -33.16 48.35 31.11 -15.10 -49.29 -38.23
Eisosomes NaN NaN NaN NaN NaN -2.52 2.33 -2.07 2.14 -3.91 -3.17 4.68 -2.07 2.74 -5.78
Endoplasmic Reticulum NaN NaN NaN NaN NaN 9.79 0.06 5.02 -8.70 3.72 9.76 -0.34 5.01 -8.67 5.03
Endosome NaN NaN NaN NaN NaN 43.12 10.24 -9.89 -41.18 -18.25 35.86 15.91 -9.82 -37.52 -22.75
Golgi NaN NaN NaN NaN NaN 56.42 -31.97 46.40 -16.78 87.60 19.65 -22.17 46.09 -1.61 87.73
Lipid Particles NaN NaN NaN NaN NaN 4.42 -1.26 -10.46 -19.68 -3.30 4.36 -1.23 -10.47 -19.71 -6.92
Mitochondria NaN NaN NaN NaN NaN 14.59 13.01 12.26 -7.99 -2.08 14.59 12.18 12.26 -7.99 0.47
Mitotic Spindle NaN NaN NaN NaN NaN 2.28 2.00 -8.71 -9.22 -9.17 2.44 -4.58 -8.72 -9.25 -7.31
None NaN NaN NaN NaN NaN -2922.11 3.16 0.51 2920.66 -2.34 -38.99 1.85 0.51 38.99 -1.14
Nuclear Periphery NaN NaN NaN NaN NaN 7.58 -1.67 -11.58 -13.98 -10.83 6.84 -4.07 -11.59 -13.85 -0.31
Nuclear Periphery Foci NaN NaN NaN NaN NaN 1.05 -1.57 -1.60 -5.54 0.46 1.21 -5.44 -1.67 -7.09 6.04
Nucleolus NaN NaN NaN NaN NaN -0.46 2.39 -5.79 -4.97 -8.63 -0.07 1.73 -5.79 -6.17 -8.17
Nucleus NaN NaN NaN NaN NaN 1.93 2.02 -10.37 -10.74 -10.76 1.90 1.10 -10.39 -10.75 -10.64
Peroxisomes NaN NaN NaN NaN NaN 3.19 3.65 -13.59 -13.94 -13.96 1.87 1.89 -10.33 -13.96 -13.98
Vacuole NaN NaN NaN NaN NaN 29.04 1.97 -35.22 -47.07 -35.13 18.07 -15.73 -35.23 -43.36 -26.75
Vacuole Periphery NaN NaN NaN NaN NaN 37.02 20.68 33.97 -15.69 16.30 33.94 9.44 33.98 -5.03 39.47
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Tetra-spanning membrane protein found mostly in the late Golgi; non-essential; can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Sft2

Sft2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sft2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available