Standard name
Human Ortholog
Description Ribosomal lysine methyltransferase; specific for monomethylation of Rpl42ap and Rpl42bp (lysine 40); nuclear SET domain containing protein; relocalizes to the cytosol in response to hypoxia
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.06 0 0 0 0 0 – 0 0 0 0 0.13 0.11 0.13 0.06 0.07 0.11 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.07 0 – 0.19 0.16 0.4 0.22 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.94 0.89 0.99 0.96 0.95 0.93 0.94 – 0.9 0.92 0.84 0.86 0.85 0.89 0.81 0.83 0.85 0.78 0.92 0.88 0.9 0.88 0.75 0.72
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.11 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0.05 0.09 0 0.07 0.07 0 0.18 0.2
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 1 1 – 1 3 4 2 0 0 0 0 0 0 2 1 1 0 1 0
Bud Neck 0 0 0 0 1 0 0 – 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 0 – 3 2 13 9 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 7 6 0 7 14 7 15 – 8 9 17 24 7 20 29 6 13 25 1 1 0 1 1 1
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 2 1 6 1 0 0 0 0 0
Endosome 0 0 0 0 0 1 1 – 0 0 0 0 0 0 3 2 0 2 1 0 0 0 0 1
Golgi 0 0 0 0 1 0 0 – 0 0 0 0 0 0 2 0 0 2 1 0 0 0 0 0
Mitochondria 6 1 0 0 1 29 34 – 84 77 174 123 0 0 0 2 2 2 1 0 0 0 1 1
Nucleus 191 97 87 267 541 411 748 – 402 453 367 486 47 165 188 91 161 174 185 97 82 30 93 94
Nuclear Periphery 0 0 0 0 5 2 4 – 2 1 2 4 0 2 3 0 1 4 0 0 0 0 0 0
Nucleolus 2 2 0 1 2 0 7 – 7 5 9 7 0 2 6 4 6 5 1 0 0 0 3 3
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 2 3 1 4 – 3 3 3 7 1 3 6 0 1 1 0 0 0 0 0 1
Vac/Vac Membrane 5 12 1 5 14 13 17 – 5 7 9 9 1 3 8 6 10 19 6 7 6 1 22 25
Unique Cell Count 204 109 88 277 569 443 792 445 495 439 562 55 186 231 109 189 222 202 111 92 34 124 132
Labelled Cell Count 211 118 88 282 582 466 831 515 563 599 671 56 195 247 113 195 240 202 111 92 34 124 132


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.5 7.6 6.6 7.2 7.3 5.8 6.0 – 4.9 5.2 4.4 4.9 8.3 8.2 7.9 10.7 11.7 11.4 – 6.2 7.7
Std Deviation (1e-4) 1.1 1.9 1.2 1.2 1.3 1.0 1.0 – 1.0 0.9 0.9 1.0 2.0 1.7 1.7 2.5 2.8 8.5 – 1.0 1.7
Intensity Change (Log2) – – – 0.13 0.15 -0.18 -0.13 – -0.42 -0.34 -0.56 -0.42 0.33 0.31 0.27 0.7 0.83 0.8 – -0.07 0.23


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 – 0 0 0 0 0 3.2 3.5 0 0 3.3
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 4.4 4.0 0 4.9 0 0 0 0 0 0
Nucleus -1.2 -1.6 -2.2 -1.8 – -2.7 -2.4 -3.8 -3.3 -3.2 -2.9 -4.0 -3.6 -3.5 -4.5
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 2.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.5931 2.5367 2.3361 2.0193 2.1719 2.1959 2.247 2.4763 2.2045 2.1393 1.7189 2.0691 1.1971 1.5305 1.088 1.5311 1.056 0.753
Actin 0.0078 0 0.0067 0 0 0.0015 0.0268 0 0.0055 0.0007 0.0226 0.0038 0.0383 0 0.0168 0.0258 0 0
Bud 0.0001 0 0.0003 0 0 0 0.0004 0.0001 0.0004 0.0003 0.0002 0.0004 0.0003 0 0.0004 0.0005 0 0
Bud Neck 0.0003 0.0002 0.0018 0.0002 0.0002 0.0008 0.0012 0.0002 0.0006 0.0001 0.0009 0.001 0.0004 0.0001 0.0051 0.0013 0.0001 0.0007
Bud Periphery 0.0002 0 0.0007 0 0 0.0001 0.0006 0.0001 0.0007 0.0004 0.0004 0.0006 0.0005 0.0001 0.0008 0.0005 0 0.0001
Bud Site 0.0002 0.0001 0.0022 0 0 0.0001 0.0013 0.0003 0.0049 0.0003 0.0012 0.0017 0.0009 0.0001 0.0062 0.0089 0 0.0001
Cell Periphery 0 0 0.0005 0 0 0 0.0002 0.0001 0.0003 0.0001 0.0001 0.0001 0.0003 0.0001 0.0003 0.0001 0 0
Cytoplasm 0.0017 0.0004 0.0003 0.0001 0.0001 0.0002 0.0016 0.0001 0.0005 0.0001 0.0028 0.0002 0.0009 0.0004 0.0013 0.0005 0 0.0001
Cytoplasmic Foci 0.0035 0 0.0001 0 0 0.0002 0.0043 0.0018 0.0019 0.0004 0.0192 0.0046 0.0195 0 0.0053 0.0038 0 0
Eisosomes 0 0 0.0001 0 0 0 0.0004 0 0.0001 0.0001 0.0014 0 0.0003 0 0.0001 0.0002 0 0
Endoplasmic Reticulum 0.0007 0.0003 0.0003 0 0 0.0004 0.0026 0 0.0002 0 0.0022 0.0001 0.0035 0.0001 0.0007 0.0003 0 0
Endosome 0.0029 0.0001 0.0007 0 0 0.0012 0.0099 0.0002 0.0012 0.0002 0.0259 0.0034 0.0195 0.0002 0.0073 0.0031 0 0
Golgi 0.0023 0 0.0005 0 0 0.0003 0.0022 0.0001 0.0015 0.0002 0.006 0.0033 0.0136 0 0.0025 0.0038 0 0
Lipid Particles 0.0032 0 0.0003 0 0 0.0004 0.003 0.0031 0.0048 0.0006 0.0319 0.0034 0.0103 0 0.0087 0.0029 0 0
Mitochondria 0.0007 0.0002 0.0007 0.0003 0.0002 0.0003 0.0026 0.0012 0.0125 0.0612 0.0033 0.0048 0.0067 0.0005 0.0099 0.0011 0.0001 0.0001
None 0.0008 0 0.0001 0 0 0.0001 0.0026 0.0001 0.0003 0.0001 0.0317 0 0.0016 0.0002 0.001 0.0003 0 0
Nuclear Periphery 0.0086 0.0161 0.0047 0.0012 0.0021 0.0094 0.0073 0.0032 0.0042 0.0014 0.0252 0.0002 0.0035 0.0105 0.0068 0.0033 0.0002 0.0003
Nucleolus 0.0301 0.0559 0.056 0.0581 0.1129 0.0655 0.0377 0.0328 0.0681 0.0527 0.0354 0.0455 0.0225 0.0445 0.0483 0.0468 0.0318 0.0381
Nucleus 0.9264 0.9236 0.9216 0.9353 0.882 0.915 0.887 0.949 0.8828 0.8784 0.7347 0.914 0.829 0.9417 0.8649 0.8926 0.9673 0.9598
Peroxisomes 0.0026 0 0.0001 0 0 0 0.0026 0.0009 0.0058 0.0012 0.0135 0.0113 0.0076 0 0.0051 0.0021 0 0
Punctate Nuclear 0.0067 0.0007 0.0013 0.0045 0.0022 0.0037 0.0035 0.0056 0.0014 0.0003 0.038 0.0003 0.0031 0.0008 0.0048 0.0012 0.0003 0.0003
Vacuole 0.0005 0.0017 0.0008 0 0.0001 0.0003 0.0012 0.0007 0.0017 0.0005 0.0016 0.0011 0.0109 0.0004 0.0023 0.0005 0 0.0002
Vacuole Periphery 0.0004 0.0005 0.0002 0.0001 0.0001 0.0004 0.0011 0.0006 0.0008 0.0008 0.0016 0.0002 0.0068 0.0003 0.0013 0.0003 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.2809 13.0803 21.6183 15.5359 18.5402 15.2889 14.4278 15.6211 13.7666 16.301
Translational Efficiency 0.5014 0.8449 0.4882 0.67 0.4805 0.6344 0.7993 0.4596 0.5158 0.5416

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1060 243 135 573 1598 1373 159 201 2658 1616 294 774

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 587.46 956.18 1004.52 921.16 827.09 839.01 1102.35 1003.12 731.53 856.63 1057.43 942.44
Standard Deviation 111.97 152.44 177.95 130.57 115.19 122.79 130.45 112.94 163.54 134.38 161.61 131.25
Intensity Change Log 2 — 0.702792 0.773944 0.648961 — 0.020644 0.414466 0.278378 — 0.343793 0.574758 0.443976

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000137 0.000605 0.001376 0.000974 0.000207 0.000361 0.001228 0.001127 0.000179 0.000398 0.001296 0.001013
Bud Neck 0.002024 0.008808 0.013115 0.017162 0.005141 0.007417 0.008963 0.016337 0.003898 0.007626 0.010870 0.016948
Bud Site 0.001279 0.002193 0.002008 0.003864 0.000381 0.001993 0.001095 0.003651 0.000739 0.002023 0.001514 0.003809
Cell Periphery 0.000308 0.000085 0.000056 0.000117 0.000100 0.000180 0.000066 0.000168 0.000183 0.000166 0.000061 0.000130
Cytoplasm 0.036741 0.012793 0.000836 0.014464 0.007482 0.038040 0.001231 0.018851 0.019150 0.034243 0.001050 0.015603
Cytoplasmic Foci 0.005053 0.003413 0.000041 0.005486 0.000394 0.004398 0.000040 0.003986 0.002252 0.004250 0.000040 0.005097
Eisosomes 0.000019 0.000023 0.000056 0.000027 0.000018 0.000022 0.000047 0.000041 0.000019 0.000022 0.000051 0.000031
Endoplasmic Reticulum 0.002104 0.007375 0.007370 0.009963 0.005390 0.007095 0.008716 0.008904 0.004079 0.007137 0.008098 0.009688
Endosome 0.000584 0.002257 0.000183 0.005411 0.000332 0.002342 0.000252 0.011212 0.000432 0.002329 0.000220 0.006918
Golgi 0.000361 0.001325 0.000068 0.004062 0.000098 0.001036 0.000083 0.003925 0.000203 0.001079 0.000076 0.004026
Lipid Particles 0.000969 0.002670 0.000134 0.000812 0.000442 0.001770 0.000154 0.000408 0.000652 0.001905 0.000145 0.000707
Mitochondria 0.001167 0.002095 0.001662 0.003112 0.001008 0.004513 0.001144 0.009402 0.001071 0.004149 0.001382 0.004745
Mitotic Spindle 0.002487 0.000936 0.000108 0.016761 0.000912 0.005887 0.001528 0.023204 0.001540 0.005142 0.000876 0.018434
None 0.027673 0.001164 0.001116 0.009405 0.003007 0.003609 0.001608 0.007135 0.012844 0.003241 0.001382 0.008816
Nuclear Periphery 0.001421 0.000572 0.000247 0.002056 0.000729 0.001704 0.000482 0.001089 0.001005 0.001534 0.000374 0.001805
Nuclear Periphery Foci 0.001038 0.000378 0.000076 0.001137 0.000186 0.000891 0.000192 0.000666 0.000526 0.000814 0.000138 0.001014
Nucleolus 0.009934 0.004946 0.008105 0.003544 0.017195 0.008977 0.006538 0.008086 0.014299 0.008371 0.007258 0.004723
Nucleus 0.904879* 0.934878* 0.960117* 0.879190* 0.955540* 0.900055* 0.963111* 0.860874* 0.935337* 0.905292* 0.961736* 0.874434*
Peroxisomes 0.000328 0.002907 0.000605 0.000893 0.000235 0.000824 0.000357 0.000328 0.000272 0.001137 0.000471 0.000746
Vacuole 0.001033 0.010239 0.002432 0.015371 0.000992 0.006804 0.003039 0.017937 0.001008 0.007321 0.002760 0.016037
Vacuole Periphery 0.000462 0.000338 0.000288 0.006190 0.000212 0.002083 0.000127 0.002670 0.000311 0.001821 0.000201 0.005276

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.96 -6.80 -7.59 -3.39 0.74 -2.58 -5.58 -9.01 -7.86 -0.57 -4.11 -8.33 -10.40 -7.95 0.71
Bud Neck -3.22 -4.33 -11.38 -4.32 -2.27 -2.33 -4.87 -6.52 -5.77 -4.23 -4.53 -6.04 -12.33 -9.14 -4.79
Bud Site -1.09 -1.14 -4.41 -2.67 -2.78 -2.91 -4.35 -5.13 -3.71 -3.96 -2.49 -3.08 -7.15 -4.59 -4.83
Cell Periphery 5.00 6.21 5.11 -0.82 -3.61 -2.36 0.89 -1.77 1.14 -2.72 0.63 5.59 3.51 1.87 -3.70
Cytoplasm 4.10 11.88 6.23 -0.02 -7.20 -7.79 4.00 -1.82 5.39 -4.11 -4.31 11.78 2.24 5.64 -8.16
Cytoplasmic Foci 1.15 5.05 2.13 0.40 -2.27 -5.31 2.93 -0.95 2.90 -1.43 -2.08 5.45 0.45 2.02 -2.57
Eisosomes -1.87 -5.35 -7.63 -3.81 1.82 -2.20 -6.33 -8.23 -7.47 -1.09 -2.64 -8.30 -11.06 -8.92 1.52
Endoplasmic Reticulum -6.25 -7.21 -7.76 -1.86 -2.90 -3.23 -5.06 -6.86 -5.18 -2.18 -7.06 -7.70 -8.36 -4.57 -2.68
Endosome -1.52 3.80 -2.76 -0.48 -3.29 -4.81 -0.42 -1.68 -0.72 -1.67 -4.83 2.41 -3.30 -0.87 -3.49
Golgi -0.96 1.61 -1.94 -0.54 -2.44 -2.32 -0.69 -1.56 -0.26 -1.51 -2.28 1.20 -2.57 -0.91 -2.78
Lipid Particles -0.69 6.25 2.16 0.91 -2.91 -1.89 0.78 -0.55 1.80 -4.48 -1.82 2.86 0.46 2.01 -3.39
Mitochondria -0.88 -1.12 -2.68 -0.35 -1.05 -3.44 -0.73 -1.43 0.17 -1.30 -3.67 -1.26 -2.58 1.26 -1.98
Mitotic Spindle 1.21 1.82 -3.58 -4.14 -4.35 -2.93 -1.14 -2.51 -1.64 -1.47 -2.39 -0.64 -4.57 -3.37 -3.59
None 9.11 9.09 6.39 -3.33 -3.31 -0.92 0.87 -1.17 -0.41 -1.64 7.33 8.44 4.08 -2.01 -3.23
Nuclear Periphery 2.76 5.18 -2.71 -4.89 -6.45 -3.46 0.08 -6.15 -1.84 -7.17 -2.34 3.55 -4.99 -2.74 -7.27
Nuclear Periphery Foci 1.14 1.72 0.32 -1.70 -3.62 -1.85 -0.51 -2.43 0.78 -0.88 -0.65 1.24 -0.95 -0.03 -2.84
Nucleolus 4.43 1.49 3.12 -1.39 1.15 5.01 4.63 4.25 0.40 -0.33 4.98 4.93 6.56 1.25 0.70
Nucleus -1.85 -6.61 3.00 3.82 8.18 8.62 1.16 7.52 3.36 6.19 5.09 -3.01 8.69 4.18 9.71
Peroxisomes -1.44 -1.98 -0.70 1.31 0.19 -2.31 -1.95 -1.81 1.51 0.08 -2.54 -2.82 -1.20 1.57 -0.02
Vacuole -2.99 -2.57 -7.23 -1.86 -6.74 -5.99 -3.51 -5.71 -4.79 -4.80 -6.60 -4.05 -9.19 -6.40 -7.65
Vacuole Periphery 0.42 0.59 -1.70 -1.81 -1.85 -3.46 0.78 -1.56 1.56 -1.68 -3.21 0.72 -1.98 -0.43 -2.08
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal lysine methyltransferase; specific for monomethylation of Rpl42ap and Rpl42bp (lysine 40); nuclear SET domain containing protein; relocalizes to the cytosol in response to hypoxia
Localization
Cell Percentages nucleus (95%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Rkm3

Rkm3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rkm3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available