Standard name
Human Ortholog
Description High-affinity leucine permease; functions as a branched-chain amino acid permease involved in uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains; BAP2 has a paralog, BAP3, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.06 0.06 0 0 0 0 – 0 0 0 0.07 0.08 0.13 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.15 0.12 0.3 0.34 0 0 0 0 – 0 0 0 0.54 0.55 0.32 0 0 0 0.05 0 0.18 0.3 0.32 0.25
Cytoplasm 0.21 0.22 0.1 0.17 0.08 0.1 0.2 0.2 – 0.32 0.42 0.51 0.16 0.16 0.14 0.19 0.17 0.28 0.15 0.15 0.07 0 0 0
Endoplasmic Reticulum 0.67 0.61 0.59 0.5 0.07 0 0 0 – 0 0 0 0.36 0.38 0.45 0.13 0.07 0.14 0.5 0.36 0.48 0.44 0.47 0.53
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.09 0.05 0 – 0.08 0.08 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0.18 0.24 0.23 0.21 – 0.18 0.12 0.08 0 0 0 0.41 0.32 0.26 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.08 0.06 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.07 0 0 0.72 0.67 0.67 0.69 – 0.66 0.54 0.5 0 0 0.06 0.21 0.35 0.2 0.25 0.37 0.2 0.16 0.1 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 2 14 10 4 0 0 2 – 0 0 0 17 19 25 0 0 0 0 2 4 1 2 2
Bud 6 3 2 0 0 1 2 4 – 1 3 2 5 5 3 7 0 1 1 6 2 1 1 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 22 19 68 56 4 1 0 0 – 1 1 3 127 127 63 1 1 2 11 7 49 36 31 26
Cytoplasm 31 35 23 28 18 21 61 76 – 106 112 136 38 38 27 23 17 14 32 36 19 5 2 4
Endoplasmic Reticulum 98 99 132 83 16 2 1 1 – 0 0 4 85 89 88 15 7 7 106 88 135 54 46 55
Endosome 0 0 0 0 0 3 4 2 – 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1
Golgi 2 1 1 1 4 0 0 0 – 0 0 0 2 1 7 0 2 1 0 1 0 0 0 0
Mitochondria 0 2 0 0 3 19 17 17 – 26 21 22 0 0 0 2 1 2 2 0 4 3 1 0
Nucleus 2 3 4 5 40 52 73 81 – 61 31 21 1 1 3 49 31 13 0 1 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 1 0 – 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 1 0 1 1 2 1 2 – 3 2 0 0 0 1 4 8 3 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 0 0 0 0 – 1 0 1 2 1 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 5 12 9 7 162 144 209 268 – 220 142 133 4 4 12 25 34 10 53 91 56 19 9 8
Unique Cell Count 147 162 224 166 226 215 312 388 334 265 267 235 232 196 119 98 50 215 248 280 123 99 104
Labelled Cell Count 167 177 253 192 252 245 369 453 420 313 323 281 285 229 126 101 53 215 248 280 123 99 104


Cell Periphery, Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 54.2 53.5 44.8 41.9 35.9 22.3 18.8 16.8 – 10.5 9.7 8.5 39.2 39.2 32.7 86.8 96.8 109.7 42.3 39.1 38.0
Std Deviation (1e-4) 15.4 19.3 17.0 14.5 15.6 14.8 14.5 12.2 – 8.8 8.0 6.2 9.7 9.7 9.3 33.3 37.6 50.4 11.5 13.3 12.3
Intensity Change (Log2) – – – -0.1 -0.32 -1.01 -1.25 -1.41 – -2.1 -2.2 -2.4 -0.19 -0.19 -0.45 0.95 1.11 1.29 -0.08 -0.2 -0.24

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP700050100150WT3HU80HU120HU160050100150WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100150WT1AF100AF140AF180050100150
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.1 -2.4 -3.7 -4.5 -4.3 – -4.6 -4.1 -4.1 0.4 0.8 2.3 0 0 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0.7 -8.3 -8.6 -10.4 -11.5 – -10.6 -9.5 -9.2 5.1 5.3 0.4 -6.5 -5.9 -3.9
Cytoplasm 1.9 -0.8 -0.2 2.9 3.0 – 5.9 7.9 9.6 1.9 1.9 1.1 2.3 1.8 3.3
Endoplasmic Reticulum -1.8 -11.7 -13.2 -15.5 -17.0 – -16.1 -14.6 -14.2 -4.9 -4.4 -2.9 -8.3 -8.6 -5.7
Endosome 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.5 3.6 3.2 – 4.3 4.3 4.4 0 0 0 0 0 0
Nucleus 0 5.7 7.0 7.0 6.6 – 5.9 4.2 3.1 0 0 0 9.6 7.9 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 0.1 14.8 13.8 14.6 15.6 – 14.6 11.8 11.1 -1.5 -1.5 1.0 5.0 7.4 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 47.4856 105.3493 95.1058 90.4382 95.5651 107.261 78.2677 103.7731 101.6331 97.0801 95.8428 97.7087 86.6528 128.4868 123.2966 97.354 124.3757 137.5988
Actin 0.0055 0 0.0057 0.0003 0 0.0002 0.0072 0.0104 0.0013 0.0004 0.0439 0.0001 0.0185 0.0009 0.006 0.0081 0 0
Bud 0.0009 0.0001 0.0012 0.0002 0.0002 0.0001 0.0006 0.0001 0.0004 0.0029 0.0034 0.0001 0.0009 0.0001 0.0005 0.0003 0.0001 0
Bud Neck 0.0039 0.0004 0.0011 0.0001 0.0001 0.0001 0.0006 0.0003 0.0002 0.0001 0.0002 0.0003 0.0006 0.0005 0.0006 0.0014 0.0004 0.0001
Bud Periphery 0.002 0.0005 0.0013 0.0005 0.0004 0.0007 0.0009 0.0004 0.0006 0.0081 0.0059 0.0005 0.0018 0.0004 0.001 0.0012 0.0006 0.0003
Bud Site 0.0312 0.0006 0.0062 0.0002 0.0002 0.0001 0.0149 0.0002 0.0155 0.0012 0.0008 0.0002 0.0032 0.0084 0.0093 0.0004 0.0003 0
Cell Periphery 0.1916 0.3072 0.2998 0.2829 0.3432 0.3721 0.3949 0.3962 0.395 0.4215 0.3601 0.4403 0.3831 0.3883 0.4219 0.3396 0.4267 0.4186
Cytoplasm 0.0866 0.0056 0.0148 0.0457 0.0023 0.0121 0.052 0.0005 0.0095 0.0021 0.0062 0.0078 0.0267 0.001 0.0025 0.003 0.0001 0.0002
Cytoplasmic Foci 0.0378 0.0005 0.0178 0.0015 0.0112 0.0014 0.0238 0.0002 0.0004 0.001 0.022 0.0134 0.0154 0.0003 0.0039 0.0337 0.0001 0
Eisosomes 0.0018 0.0001 0.0003 0 0 0 0.0004 0.0001 0.0001 0.0055 0.0003 0.0002 0.0006 0.0002 0.0004 0.0006 0 0
Endoplasmic Reticulum 0.0512 0.0002 0.0062 0.004 0.0001 0.0041 0.0429 0.0006 0.0054 0.0011 0.0031 0.001 0.019 0.0025 0.0042 0.0436 0.0002 0.0005
Endosome 0.0305 0.0006 0.0103 0.0037 0.0004 0.0064 0.0117 0.0005 0.0005 0.0002 0.0022 0.0013 0.0086 0.0005 0.0011 0.004 0.0004 0.0005
Golgi 0.0028 0.0001 0.0062 0.0002 0 0.0016 0.0024 0.0004 0.0002 0.0001 0.0034 0.0003 0.0058 0.0002 0.0013 0.0059 0 0.0001
Lipid Particles 0.046 0.0083 0.008 0.0047 0.0053 0.0075 0.0275 0.0241 0.0181 0.0079 0.0411 0.0315 0.0174 0.0263 0.011 0.0245 0.0229 0.0057
Mitochondria 0.0045 0.0005 0.0041 0.0007 0.0015 0.0007 0.0011 0.0003 0.0003 0.0129 0.0034 0.0008 0.0052 0.0012 0.0011 0.0034 0.0004 0.0001
None 0.0537 0.0001 0.006 0.0008 0.0019 0.0003 0.0017 0 0 0.0131 0.0038 0.009 0.0055 0.0001 0.0014 0.006 0 0
Nuclear Periphery 0.0248 0.0012 0.0024 0.0032 0.0004 0.0007 0.0163 0.0017 0.0018 0.0009 0.0013 0.0009 0.0075 0.0024 0.0023 0.0029 0.0003 0.0007
Nucleolus 0.065 0.0254 0.0243 0.0109 0.0929 0.0025 0.0024 0.0048 0.0062 0.0055 0.0227 0.0055 0.0443 0.0124 0.0163 0.0124 0.0151 0.0019
Nucleus 0.0238 0.0054 0.0041 0.0043 0.009 0.0018 0.0038 0.002 0.0016 0.0017 0.0061 0.0018 0.0125 0.0065 0.0022 0.0031 0.0021 0.0008
Peroxisomes 0.0008 0.0001 0.0008 0.0001 0.0002 0 0.0014 0 0.0001 0.0004 0.0002 0.0002 0.0003 0.0001 0.0005 0.0008 0.0001 0
Punctate Nuclear 0.0106 0 0.0012 0.0003 0.0003 0 0.0045 0 0 0 0.0017 0.0004 0.0043 0.0001 0.0002 0.001 0 0
Vacuole 0.2994 0.6001 0.5435 0.601 0.4997 0.5713 0.3768 0.5371 0.5246 0.5057 0.4519 0.4577 0.3965 0.5204 0.488 0.4725 0.5137 0.5473
Vacuole Periphery 0.0255 0.043 0.0347 0.0346 0.0308 0.0161 0.0121 0.0201 0.0181 0.0079 0.0164 0.0266 0.0223 0.0271 0.0245 0.0316 0.0166 0.023

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 96.774 92.7086 80.7927 90.6535 80.1299 107.8689 136.1102 130.2113 110.498 130.2756
Translational Efficiency 0.8797 0.9281 0.9025 0.6779 0.9238 1.042 0.8551 0.7361 0.7881 0.7031

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
119 778 1361 739 81 976 2253 1522 200 1754 3614 2261

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1956.02 6168.04 4996.23 4341.06 4042.99 5081.67 4461.56 4334.62 2801.24 5563.54 4662.91 4336.72
Standard Deviation 667.15 1563.67 980.77 1017.36 1241.76 1348.27 885.65 1047.05 1392.44 1545.10 958.30 1037.44
Intensity Change Log 2 — 1.656891 1.352919 1.150126 — 0.329880 0.142126 0.100483 — 0.907091 0.656779 0.532252

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002021 0.000119 0.000964 0.002648 0.000139 0.001154 0.000609 0.001899 0.001259 0.000695 0.000742 0.002144
Bud Neck 0.010103 0.000673 0.001926 0.001735 0.001836 0.002808 0.000609 0.000973 0.006755 0.001861 0.001105 0.001222
Bud Site 0.034577 0.001381 0.003063 0.006760 0.024373 0.007495 0.001982 0.009546 0.030444 0.004783 0.002389 0.008636
Cell Periphery 0.402888 0.474385 0.657855 0.543124 0.507598 0.480756 0.882576 0.634158 0.445295 0.477930 0.797948 0.604404
Cytoplasm 0.048405 0.000147 0.002056 0.013105 0.005344 0.004381 0.002011 0.002735 0.030965 0.002503 0.002028 0.006125
Cytoplasmic Foci 0.011446 0.000012 0.000117 0.000275 0.000118 0.000729 0.000080 0.000881 0.006858 0.000411 0.000094 0.000683
Eisosomes 0.000689 0.001559 0.002690 0.000842 0.000574 0.000476 0.001061 0.000588 0.000643 0.000956 0.001674 0.000671
Endoplasmic Reticulum 0.041525 0.004711 0.008300 0.004330 0.006534 0.006419 0.000981 0.004572 0.027354 0.005662 0.003737 0.004493
Endosome 0.018407 0.000211 0.000658 0.000422 0.000149 0.001016 0.000220 0.001031 0.011012 0.000659 0.000385 0.000832
Golgi 0.008583 0.000593 0.001811 0.001988 0.000738 0.001426 0.000473 0.001694 0.005405 0.001056 0.000977 0.001790
Lipid Particles 0.027377 0.000651 0.023632 0.018395 0.001339 0.003105 0.001292 0.008512 0.016831 0.002017 0.009705 0.011742
Mitochondria 0.000803 0.000049 0.000202 0.000960 0.000096 0.000280 0.000251 0.000759 0.000517 0.000178 0.000232 0.000825
Mitotic Spindle 0.000797 0.000185 0.001483 0.000643 0.000136 0.000161 0.000722 0.000786 0.000529 0.000171 0.001009 0.000739
None 0.000061 0.000015 0.000036 0.000035 0.000015 0.000055 0.000012 0.000052 0.000042 0.000037 0.000021 0.000046
Nuclear Periphery 0.001453 0.002714 0.017485 0.006803 0.000290 0.002630 0.006444 0.007736 0.000982 0.002667 0.010602 0.007431
Nuclear Periphery Foci 0.002011 0.000245 0.001003 0.000965 0.000723 0.000689 0.000207 0.000513 0.001489 0.000492 0.000507 0.000660
Nucleolus 0.000056 0.000042 0.000125 0.000099 0.000044 0.000048 0.000082 0.000129 0.000051 0.000046 0.000098 0.000119
Nucleus 0.001606 0.000078 0.000478 0.000365 0.000409 0.000219 0.000215 0.000301 0.001121 0.000156 0.000314 0.000322
Peroxisomes 0.001335 0.000030 0.000986 0.000154 0.000010 0.000111 0.000141 0.000378 0.000799 0.000075 0.000459 0.000305
Vacuole 0.377432 0.510110 0.269431 0.391658 0.447360 0.484203 0.096622 0.318583 0.405753 0.495694 0.161700 0.342467
Vacuole Periphery 0.008426 0.002090 0.005701 0.004695 0.002175 0.001838 0.003410 0.004172 0.005894 0.001950 0.004273 0.004343

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.81 2.10 -0.26 -1.89 -1.22 -1.67 -2.90 -3.57 -1.03 -2.56 1.44 1.76 -1.23 -2.30 -2.53
Bud Neck 3.96 3.40 3.42 -2.29 0.28 -1.07 2.65 1.75 2.74 -1.97 3.29 3.90 3.76 1.43 -0.72
Bud Site 3.65 3.48 3.06 -3.30 -2.30 1.06 1.46 0.91 -0.92 -4.45 3.20 3.52 2.70 -2.52 -4.96
Cell Periphery -2.66 -9.23 -4.94 -5.47 10.36 0.75 -13.43 -4.50 -14.98 33.11 -1.79 -17.43 -7.75 -15.96 29.44
Cytoplasm 3.59 3.45 2.61 -5.10 -4.30 0.95 1.21 1.10 0.94 -1.44 3.55 3.62 3.13 -3.29 -4.40
Cytoplasmic Foci 2.11 2.09 2.06 -2.63 -1.63 -1.88 0.99 -1.76 -0.27 -2.01 1.98 2.09 1.89 -0.82 -2.18
Eisosomes -1.19 -5.49 -0.79 0.99 5.08 0.23 -1.22 -0.06 -1.23 3.75 -0.87 -4.52 -0.18 0.87 6.38
Endoplasmic Reticulum 3.27 2.95 3.30 0.33 3.48 0.00 1.39 0.47 1.31 -4.25 3.09 3.38 3.26 1.23 -1.09
Endosome 3.34 3.26 3.30 -2.07 2.43 -1.78 -2.01 -2.58 -0.02 -2.38 3.12 3.22 3.07 -0.49 -1.96
Golgi 2.33 1.97 1.89 -2.44 -0.34 -0.94 0.63 -1.60 -0.37 -2.89 2.07 2.15 1.72 -1.53 -2.42
Lipid Particles 4.55 0.53 1.32 -6.28 1.40 -2.59 0.13 -5.01 -3.66 -4.99 4.08 1.87 1.25 -7.21 -1.30
Mitochondria 1.84 1.46 -0.21 -1.52 -1.26 -1.36 -1.14 -2.14 -1.45 -1.57 1.31 1.11 -0.83 -2.21 -2.03
Mitotic Spindle 1.88 -2.02 0.49 -12.08 13.45 -0.33 -7.13 -7.13 -13.27 -1.28 1.81 -2.35 -1.01 -16.61 6.49
None 1.62 1.03 1.02 -1.48 0.04 -1.51 0.94 -1.51 0.10 -2.01 0.41 1.49 -0.01 -0.48 -1.89
Nuclear Periphery -3.11 -21.74 -8.93 -7.25 12.87 -10.27 -22.36 -20.14 -12.30 -2.88 -6.56 -26.01 -18.17 -14.27 7.48
Nuclear Periphery Foci 6.23 3.54 3.40 -5.67 0.24 0.43 1.86 1.01 0.62 -8.36 3.81 4.61 3.83 -1.03 -3.27
Nucleolus 1.05 -5.33 -1.21 -1.57 0.44 0.02 -2.88 -1.62 -1.65 -1.04 0.78 -5.23 -1.90 -2.11 -0.77
Nucleus 2.57 1.99 2.14 -4.12 1.28 1.00 1.01 0.92 -1.06 -1.19 2.33 2.10 2.04 -2.56 -0.46
Peroxisomes 2.16 0.53 1.95 -2.79 3.68 -2.01 -8.76 -3.49 -2.29 -2.23 1.99 0.90 1.33 -2.96 1.38
Vacuole -5.21 4.28 -0.59 9.85 -11.77 -1.41 12.48 4.40 16.50 -31.22 -4.78 12.94 3.18 19.90 -29.55
Vacuole Periphery 1.87 0.79 1.06 -3.63 1.29 0.49 -2.24 -2.76 -4.07 -1.59 1.93 0.79 0.72 -5.44 -0.25
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description High-affinity leucine permease; functions as a branched-chain amino acid permease involved in uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains; BAP2 has a paralog, BAP3, that arose from the whole genome duplication
Localization
Cell Percentages ER (22%), cytoplasm (10%), mixed (46%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Bap2

Bap2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bap2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available