Standard name
Human Ortholog
Description Protein of unknown function; required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.17 0.07 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0.13 0.17 0.12 0.29 0.1 0.12 0.21 0.23 0.19
Bud 0.06 0.05 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.07 0.05 0.08
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.05 0.12 0.05 0.05 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0.09 0.08 0.2 0.15 0.12 0.17
Cytoplasm 0.45 0.67 0.9 0.92 0.93 0.9 0.91 0.9 0.75 0.71 0.67 0.68 0.82 0.81 0.86 0.14 0.16 0.15 0.06 0.22 0.2 0.13 0.1 0.14
Endoplasmic Reticulum 0.27 0.1 0 0 0 0 0 0 0 0 0 0 0.06 0 0.05 0.08 0.05 0.05 0.27 0.15 0.1 0.14 0.15 0.13
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.05 0.35 0.25 0.32 0 0.05 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.08 0 0 0 0 0 0
Mitochondria 0.15 0.11 0 0 0 0.09 0.1 0.05 0.29 0.3 0.37 0.34 0 0 0 0.09 0.15 0.1 0.11 0.2 0.21 0.19 0.23 0.17
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0.1 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.29 0.28 0.32 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.09 0.06 0.05 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 13 10 10 11 11 5 9 7 5 3 2 1 15 5 7 32 22 13 37 21 50 54 87 81
Bud 5 7 4 3 3 3 9 8 27 26 23 18 10 8 6 8 1 1 0 0 2 3 3 3
Bud Neck 0 4 16 14 30 16 14 15 13 8 3 4 0 2 1 2 1 1 5 6 24 19 18 31
Bud Site 1 0 0 0 0 2 0 0 2 1 1 2 0 0 0 0 0 1 – – – – – –
Cell Periphery 3 7 42 14 25 20 18 11 8 5 3 6 13 9 15 0 1 0 10 17 82 38 46 69
Cytoplasm 35 99 319 287 437 440 571 527 427 350 365 329 182 323 366 36 21 17 7 45 86 32 38 59
Endoplasmic Reticulum 21 14 11 2 5 5 6 8 0 3 0 1 14 5 22 21 6 6 34 30 42 36 56 55
Endosome 0 2 0 0 1 0 0 0 0 0 1 1 4 34 20 88 33 35 5 10 7 3 10 14
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 5 10 9 1 3 1 2 2 4
Mitochondria 12 16 0 3 6 42 61 31 166 148 199 166 9 3 3 23 20 11 14 41 89 50 89 69
Nucleus 0 1 0 0 0 1 1 7 2 3 7 4 0 0 0 2 1 3 0 2 0 0 0 0
Nuclear Periphery 1 0 0 0 1 0 1 0 0 2 0 0 0 0 0 0 3 1 0 1 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 0 1 0 0 0 0 0 0 1
Peroxisomes 0 1 0 0 0 0 0 0 0 0 0 0 0 29 7 25 2 1 2 1 0 2 6 4
SpindlePole 2 3 4 7 3 3 6 7 6 9 9 14 4 25 12 74 37 35 0 2 1 0 2 2
Vac/Vac Membrane 0 0 0 0 0 1 0 2 5 6 7 7 0 1 0 10 7 2 5 18 23 13 13 16
Unique Cell Count 78 147 356 311 469 489 627 587 566 493 544 487 223 398 427 255 131 111 128 205 423 261 381 419
Labelled Cell Count 93 164 406 341 522 538 696 623 663 564 620 553 251 446 459 326 166 136 128 205 423 261 381 419


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.6 4.6 5.1 4.5 5.0 4.0 4.2 4.6 3.6 3.6 3.4 4.0 4.4 4.8 4.7 7.2 7.6 7.2 4.5 4.3 4.7
Std Deviation (1e-4) 0.6 1.4 0.7 0.8 0.9 0.9 0.9 0.9 0.7 0.8 0.5 0.8 0.6 1.7 1.0 1.4 1.8 1.3 2.2 1.2 1.1
Intensity Change (Log2) – – – -0.18 -0.03 -0.34 -0.3 -0.17 -0.52 -0.49 -0.58 -0.35 -0.22 -0.1 -0.11 0.49 0.58 0.5 -0.18 -0.26 -0.13


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.358 -0.2881 -0.372 -0.039 -0.2532 -0.3724 -0.2059 -0.3089 -0.3829 -0.6213 -0.993 -0.2764 -0.5199 0.0048 -0.2545 0.0208 -0.6373 -0.3835
Actin 0.0189 0.0166 0.018 0.0287 0.0086 0.0116 0.0663 0.0266 0.0453 0.0438 0.0028 0.0197 0.02 0.0147 0.0355 0.0063 0.0178 0.0154
Bud 0.0007 0.0009 0.0007 0.0015 0.0007 0.0002 0.001 0.0078 0.0017 0.0004 0.0002 0.0021 0.0002 0.0003 0.0007 0.0002 0.0001 0.0002
Bud Neck 0.008 0.003 0.0089 0.0013 0.0036 0.0087 0.0056 0.0035 0.0095 0.0079 0.0028 0.0196 0.0036 0.005 0.004 0.0062 0.001 0.0058
Bud Periphery 0.0015 0.0015 0.0015 0.015 0.0013 0.0004 0.0019 0.004 0.0029 0.0007 0.0005 0.0055 0.0002 0.0007 0.0009 0.0003 0.0001 0.0005
Bud Site 0.0082 0.0287 0.0152 0.0011 0.0182 0.0003 0.0173 0.0281 0.0113 0.0007 0.0016 0.0011 0.0012 0.0104 0.0047 0.0014 0.0003 0.0006
Cell Periphery 0.0021 0.0025 0.0029 0.0006 0.0008 0.0009 0.0021 0.0023 0.0019 0.0028 0.0012 0.0021 0.0009 0.0156 0.0019 0.0005 0.0002 0.0031
Cytoplasm 0.1059 0.1142 0.0984 0.0367 0.081 0.2009 0.1659 0.1446 0.1764 0.1038 0.2865 0.2108 0.0943 0.2449 0.1764 0.1738 0.1098 0.2648
Cytoplasmic Foci 0.2188 0.2138 0.2092 0.2131 0.2446 0.2033 0.1864 0.2519 0.2351 0.2972 0.1868 0.2673 0.2351 0.1787 0.2109 0.3591 0.2828 0.2613
Eisosomes 0.0026 0.0012 0.0016 0.0003 0.0006 0.0004 0.0007 0.0004 0.0004 0.0013 0.0002 0.0004 0.0004 0.0007 0.0006 0.0001 0.0001 0.0003
Endoplasmic Reticulum 0.0096 0.0136 0.0144 0.0041 0.012 0.0125 0.0116 0.0101 0.0126 0.0045 0.0039 0.0118 0.013 0.0397 0.0227 0.0616 0.0043 0.0148
Endosome 0.1063 0.1639 0.1384 0.169 0.1259 0.088 0.1451 0.157 0.1654 0.1984 0.1293 0.1121 0.1488 0.1106 0.1397 0.1617 0.1087 0.105
Golgi 0.0178 0.02 0.0219 0.064 0.0166 0.0157 0.0318 0.0327 0.0334 0.0239 0.0124 0.0305 0.0285 0.018 0.0262 0.0135 0.0227 0.017
Lipid Particles 0.1808 0.128 0.1283 0.1148 0.1879 0.1166 0.152 0.1132 0.1028 0.1121 0.1558 0.096 0.2369 0.0931 0.1239 0.0789 0.1508 0.0989
Mitochondria 0.0147 0.0116 0.0073 0.046 0.0115 0.0067 0.0057 0.0046 0.0047 0.0024 0.0007 0.0104 0.0031 0.0014 0.0037 0.0011 0.0011 0.0025
None 0.2295 0.2415 0.2807 0.2376 0.1897 0.2903 0.1172 0.1649 0.1335 0.122 0.1563 0.1654 0.1531 0.24 0.2093 0.0609 0.244 0.1677
Nuclear Periphery 0.0096 0.0021 0.0032 0.0028 0.0096 0.0011 0.0267 0.001 0.0063 0.0013 0.0009 0.0013 0.0055 0.0016 0.0018 0.0042 0.0006 0.0019
Nucleolus 0.0011 0.001 0.0014 0.0006 0.0107 0.0005 0.0009 0.0011 0.0006 0.0002 0.0005 0.0003 0.0006 0.0011 0.0002 0.0001 0.0001 0.0004
Nucleus 0.006 0.0011 0.0022 0.0009 0.0039 0.0011 0.0044 0.0017 0.0032 0.0005 0.0011 0.001 0.0031 0.0009 0.0007 0.0005 0.0004 0.001
Peroxisomes 0.0377 0.0208 0.0293 0.0468 0.0369 0.0296 0.0401 0.031 0.0398 0.0668 0.0375 0.0301 0.026 0.0094 0.0269 0.0593 0.0496 0.0233
Punctate Nuclear 0.0126 0.0038 0.0057 0.0024 0.0278 0.0047 0.0068 0.0041 0.0033 0.0027 0.0161 0.0029 0.0203 0.0032 0.0029 0.0051 0.0036 0.0095
Vacuole 0.006 0.0093 0.0092 0.0079 0.0062 0.0058 0.0079 0.0087 0.0085 0.006 0.0028 0.0085 0.0044 0.0095 0.0057 0.0044 0.0017 0.0053
Vacuole Periphery 0.0014 0.0009 0.0016 0.0046 0.002 0.0006 0.0026 0.0007 0.0014 0.0008 0.0003 0.001 0.0008 0.0006 0.0007 0.0008 0.0003 0.0009

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 3.9691 8.0424 5.9678 8.2015 2.7446 4.2313 7.4142 8.3939 9.0159 8.8908
Translational Efficiency 0.8402 0.4743 0.6184 0.4387 1.1291 0.8221 0.7595 0.4469 0.5583 0.403

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1426 1192 270 912 1340 382 866 951 2766 1574 1136 1863

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 656.15 741.44 1055.09 863.83 701.30 785.87 881.41 836.19 678.02 752.22 922.69 849.72
Standard Deviation 66.26 109.80 111.00 128.16 90.01 100.35 105.40 115.48 81.84 109.25 129.85 122.63
Intensity Change Log 2 — 0.176304 0.685269 0.396722 — 0.164259 0.329782 0.253799 — 0.170094 0.512552 0.324653

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.009068 0.027672 0.002780 0.049385 0.009784 0.009557 0.004372 0.012803 0.009415 0.023275 0.003994 0.030711
Bud Neck 0.034866 0.013476 0.012082 0.016760 0.023302 0.032764 0.007603 0.018542 0.029264 0.018157 0.008667 0.017670
Bud Site 0.008116 0.009794 0.023499 0.069285 0.010013 0.010729 0.015027 0.045977 0.009035 0.010021 0.017040 0.057387
Cell Periphery 0.003006 0.000509 0.002082 0.001328 0.001528 0.001330 0.000697 0.000606 0.002290 0.000708 0.001026 0.000959
Cytoplasm 0.321273* 0.109668* 0.177563* 0.174151* 0.291639* 0.180387* 0.397995* 0.194103* 0.306917* 0.126831* 0.345603* 0.184336*
Cytoplasmic Foci 0.249335* 0.346978* 0.043937 0.195011* 0.298449* 0.311551* 0.124073 0.222550* 0.273128* 0.338380* 0.105027 0.209068*
Eisosomes 0.023061 0.004641 0.000413 0.001728 0.007553 0.009081 0.000420 0.000651 0.015548 0.005719 0.000418 0.001178
Endoplasmic Reticulum 0.007944 0.006115 0.037820 0.018114 0.008304 0.004513 0.008088 0.005532 0.008118 0.005726 0.015154 0.011691
Endosome 0.021883 0.073043 0.014037 0.038861 0.031042 0.066581 0.013519 0.067974 0.026320 0.071475 0.013642 0.053722
Golgi 0.070836 0.090219 0.000317 0.010120 0.064859 0.090548 0.001007 0.009594 0.067940 0.090299 0.000843 0.009851
Lipid Particles 0.117880* 0.137228* 0.013187 0.059917 0.113694* 0.111783* 0.017831 0.061563 0.115852* 0.131052* 0.016727 0.060757
Mitochondria 0.016213 0.011994 0.000608 0.002109 0.008886 0.020595 0.000498 0.002529 0.012664 0.014081 0.000524 0.002323
Mitotic Spindle 0.000378 0.005830 0.004240 0.027851 0.000494 0.000564 0.005337 0.051556 0.000434 0.004552 0.005076 0.039952
None 0.002334 0.002128 0.000572 0.000413 0.002840 0.000699 0.002801 0.001639 0.002579 0.001782 0.002271 0.001039
Nuclear Periphery 0.000253 0.000198 0.002384 0.000614 0.000403 0.000286 0.001599 0.001276 0.000325 0.000219 0.001785 0.000952
Nuclear Periphery Foci 0.000624 0.001217 0.017081 0.012919 0.001375 0.000799 0.011153 0.010580 0.000988 0.001115 0.012562 0.011725
Nucleolus 0.000561 0.000390 0.000366 0.000556 0.000772 0.000295 0.000867 0.003164 0.000663 0.000367 0.000748 0.001888
Nucleus 0.031283 0.014173 0.278266* 0.054074 0.044854 0.016978 0.210752* 0.066824 0.037857 0.014854 0.226798* 0.060582
Peroxisomes 0.062016 0.121147* 0.001307 0.059298 0.056386 0.086743 0.012147 0.065296 0.059289 0.112798* 0.009570 0.062360
Vacuole 0.017958 0.022238 0.367190* 0.204521* 0.022771 0.037228 0.164045 0.154050 0.020290 0.025876 0.212328* 0.178757
Vacuole Periphery 0.001112 0.001342 0.000271 0.002983 0.001053 0.006989 0.000171 0.003192 0.001084 0.002712 0.000195 0.003090

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.19 6.08 -7.90 -2.69 -9.83 0.12 4.64 -0.24 -0.33 -3.92 -6.05 6.33 -7.16 -0.58 -10.10
Bud Neck 8.90 9.76 8.04 -1.52 -2.25 -2.25 8.37 2.74 3.75 -5.86 5.86 13.74 7.81 0.90 -6.95
Bud Site -1.25 -3.72 -12.11 -11.52 -7.03 -0.30 -2.23 -7.90 -6.82 -6.44 -0.81 -4.34 -14.28 -13.47 -10.73
Cell Periphery 9.50 4.18 7.34 -4.37 4.94 0.74 6.69 7.68 3.33 2.17 9.11 9.38 10.08 -1.13 1.69
Cytoplasm 26.74 14.69 16.20 -7.49 -1.22 9.21 -5.50 9.92 -0.74 13.91 28.07 -0.01 18.23 -7.99 13.78
Cytoplasmic Foci -12.40 36.68 9.57 20.18 -21.12 -1.09 24.38 10.97 8.80 -10.82 -10.10 31.90 14.30 21.45 -15.67
Eisosomes 12.05 16.24 15.40 4.85 -6.40 -0.99 11.79 11.50 5.94 -2.33 9.97 19.14 18.31 7.84 -6.55
Endoplasmic Reticulum 1.60 -11.88 -5.46 -6.54 7.04 2.45 -0.99 2.70 -0.81 4.90 2.65 -7.96 -3.34 -5.43 3.97
Endosome -13.45 5.88 -3.75 9.23 -7.13 -6.20 7.60 -6.32 1.31 -11.12 -13.95 8.59 -7.42 6.80 -12.69
Golgi -4.06 27.57 23.18 21.22 -7.43 -3.46 21.14 17.67 12.08 -4.66 -5.67 34.01 28.55 24.46 -7.86
Lipid Particles -2.75 25.56 11.80 12.50 -10.33 0.22 19.89 10.05 6.43 -8.15 -2.65 30.43 15.41 14.39 -12.05
Mitochondria 2.30 9.90 8.86 9.15 -2.44 -3.36 8.99 6.79 5.47 -4.78 -0.92 13.01 11.03 10.41 -4.96
Mitotic Spindle -4.47 -1.29 -7.28 -5.19 -5.05 -0.35 -4.01 -9.42 -9.40 -7.77 -4.46 -4.20 -11.77 -9.96 -9.06
None 0.11 3.88 4.12 1.91 1.21 2.95 0.47 1.35 -2.40 0.62 0.91 0.90 3.23 0.96 1.24
Nuclear Periphery 1.14 -16.74 -8.09 -9.02 11.82 0.58 -10.45 -5.83 -5.67 1.24 1.40 -17.35 -7.94 -9.15 6.17
Nuclear Periphery Foci -3.04 -13.18 -11.17 -10.63 0.65 1.85 -9.32 -8.32 -8.66 0.16 -0.81 -12.87 -13.66 -13.44 -0.02
Nucleolus 1.00 1.65 -0.46 -1.85 -2.72 1.64 -0.78 -3.98 -4.64 -3.79 1.70 -1.04 -4.01 -4.71 -3.58
Nucleus 10.24 -17.29 -7.78 -12.27 14.73 10.07 -21.39 -5.49 -11.36 15.82 14.96 -27.88 -9.18 -16.91 21.91
Peroxisomes -10.38 22.67 3.35 12.14 -13.58 -4.09 13.19 0.82 4.41 -9.91 -11.56 21.41 2.83 12.83 -14.49
Vacuole -2.29 -25.90 -27.85 -27.01 7.87 -3.37 -25.10 -22.55 -18.86 0.76 -3.20 -33.29 -35.52 -33.63 2.66
Vacuole Periphery -1.53 9.04 -1.29 -1.03 -2.32 -3.26 8.15 -1.51 2.37 -2.62 -3.54 12.54 -1.98 0.64 -3.54
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1
Localization
Cell Percentages ER (34%), cytoplasm (3%), mixed (47%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mtc4

Mtc4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mtc4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available