Standard name
Human Ortholog
Description Third subunit of DNA polymerase delta; involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; forms a complex with Rev3p, Rev7p and Pol31p; interacts with Hys2p, PCNA (Pol30p), and Pol1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.97 0.98 0.99 0.99 0.99 0.97 0.89 0.87 0.75 0.89 0.72 0.72 0.99 1.0 1.0 – – – 0.81 0.74 0.79 0.86 0.89 0.85
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0.05 0 0 0 0 0.08 0.18 0.19 0.32 0.23 0.52 0.32 0 0 0 – – – 0.07 0.12 0.1 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0.06 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 1 0 0 0 1 0 0 0 0 0 0 – – – 1 1 1 0 1 3
Bud 0 1 0 0 0 0 5 3 3 1 3 3 0 0 0 – – – 1 0 0 1 1 4
Bud Neck 0 0 5 2 6 5 6 8 5 4 2 6 1 0 0 – – – 0 1 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 – – – – – – – – –
Cell Periphery 1 0 0 2 0 4 1 0 0 0 0 0 5 0 0 – – – 2 1 1 0 0 0
Cytoplasm 252 182 166 198 268 283 348 275 194 270 173 163 153 139 158 – – – 222 145 126 59 130 158
Endoplasmic Reticulum 1 1 1 0 2 0 0 0 5 1 1 2 1 0 0 – – – 0 1 1 0 0 0
Endosome 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 – – – 2 2 1 0 0 1
Golgi 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 1 1 0 0 0 0
Mitochondria 14 3 0 0 5 23 71 59 83 69 125 72 0 0 0 – – – 20 23 15 2 3 2
Nucleus 0 1 0 0 1 2 2 3 3 0 0 1 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 1 0 0 1 1 1 7 4 2 1 4 3 0 0 0 – – – 7 2 1 1 2 1
Vac/Vac Membrane 1 0 0 0 0 4 6 1 2 1 5 2 0 0 1 – – – 5 11 1 1 1 3
Unique Cell Count 260 185 167 201 272 293 390 317 258 302 241 227 154 139 158 274 197 159 69 147 186
Labelled Cell Count 271 189 173 204 284 322 446 353 298 348 314 253 160 139 159 274 197 159 69 147 186


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.2 3.9 4.5 4.4 4.3 3.6 3.3 3.8 2.9 3.2 2.9 3.3 4.5 4.8 4.8 – 4.9 – 4.3 4.5 5.3
Std Deviation (1e-4) 0.7 0.9 1.3 1.6 1.3 1.6 1.5 1.5 0.7 0.9 1.0 0.9 1.1 1.1 1.4 – 0.8 – 1.9 1.5 2.1
Intensity Change (Log2) – – – -0.05 -0.08 -0.34 -0.44 -0.25 -0.63 -0.5 -0.67 -0.44 0.01 0.07 0.09 – 0.11 – -0.06 -0.02 0.22

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_20246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.3445 0.0224 0.1585 0.5017 0.2693 0.2488 -0.6219 -0.5793 -0.3439 -0.7691 -0.4313 -0.6233 -1.1584 -0.2463 -0.8432 -0.687 -1.4413 -1.1215
Actin 0.0242 0.0001 0.0202 0.0779 0.0024 0.045 0.0255 0.0002 0.016 0.0021 0.048 0.0049 0.0447 0.0096 0.0113 0.019 0.031 0.0014
Bud 0.0006 0.0024 0.001 0.0022 0.0002 0.0003 0.001 0.0041 0.0008 0.0001 0.0026 0.0001 0.0006 0.0011 0.004 0.0004 0.0004 0.0002
Bud Neck 0.0005 0.0001 0.0002 0.0037 0.0002 0.0038 0.0195 0.0001 0.0137 0.001 0.0003 0.0006 0.0009 0.0017 0.0023 0.0002 0.0004 0.0006
Bud Periphery 0.0009 0.0023 0.0019 0.006 0.0003 0.0011 0.0038 0.0029 0.001 0.0002 0.0046 0.0002 0.0007 0.0031 0.0038 0.0008 0.0006 0.0004
Bud Site 0.0032 0.0078 0.0056 0.0097 0.0004 0.0004 0.0045 0.0036 0.0171 0.0003 0.0008 0.0002 0.0048 0.0108 0.0047 0.0007 0.0006 0.0001
Cell Periphery 0.0002 0.0001 0.0001 0.0009 0.0001 0.0003 0.0005 0.0001 0.0004 0.0002 0.0002 0 0.0002 0.0002 0.0002 0.0001 0.0001 0
Cytoplasm 0.0478 0.0653 0.0617 0.0522 0.0275 0.1076 0.0361 0.0303 0.0473 0.0699 0.0664 0.1043 0.0949 0.1362 0.1413 0.1064 0.2311 0.217
Cytoplasmic Foci 0.0487 0.0043 0.005 0.0279 0.0341 0.0195 0.0418 0.0081 0.0171 0.0117 0.0096 0.0086 0.0173 0.0115 0.0166 0.0234 0.0072 0.0095
Eisosomes 0.0005 0.0001 0.0002 0.0009 0.0001 0.0006 0.0009 0.0001 0.0006 0.0009 0.001 0.0001 0.0004 0.0002 0.0002 0.0003 0.0001 0.0001
Endoplasmic Reticulum 0.0021 0.0009 0.0009 0.0014 0.0004 0.0016 0.0036 0.0003 0.0027 0.0008 0.0034 0.001 0.0019 0.002 0.002 0.0017 0.0013 0.002
Endosome 0.0448 0.0005 0.0013 0.0173 0.0493 0.0046 0.0248 0.0008 0.0121 0.0023 0.0142 0.0049 0.0291 0.0048 0.0132 0.0079 0.0038 0.0098
Golgi 0.0213 0 0.0016 0.0103 0.0322 0.0047 0.0093 0.0001 0.0028 0.0001 0.0137 0.0027 0.0189 0.0015 0.0094 0.0036 0.0109 0.0018
Lipid Particles 0.0219 0.0003 0.0017 0.0498 0.0536 0.0046 0.017 0.0002 0.0045 0.0005 0.0366 0.0058 0.0165 0.0009 0.0031 0.0125 0.0014 0.0071
Mitochondria 0.0305 0.0002 0.0036 0.0281 0.0698 0.019 0.0077 0.0004 0.0034 0.0005 0.0438 0.0103 0.0055 0.0054 0.0049 0.0074 0.015 0.0038
None 0.6918 0.9026 0.8843 0.6321 0.6971 0.7526 0.7326 0.9414 0.8227 0.8944 0.7145 0.8018 0.7235 0.7947 0.7349 0.7623 0.659 0.6879
Nuclear Periphery 0.0134 0.0006 0.001 0.002 0.0006 0.002 0.0074 0.0004 0.0122 0.0012 0.0088 0.0025 0.0015 0.0014 0.0053 0.0037 0.0015 0.0024
Nucleolus 0.0007 0.0002 0.0003 0.0007 0.0062 0.0003 0.0042 0.0004 0.0038 0.0017 0.0009 0.0006 0.0004 0.0005 0.0022 0.0009 0.0003 0.0006
Nucleus 0.0143 0.0044 0.0025 0.0031 0.0016 0.0075 0.0121 0.0016 0.0082 0.0047 0.01 0.0353 0.0084 0.007 0.02 0.0249 0.0262 0.0283
Peroxisomes 0.0135 0.0001 0.0045 0.0678 0.008 0.0116 0.0189 0.0002 0.0032 0.0003 0.0096 0.0033 0.0257 0.0026 0.0045 0.0131 0.003 0.0014
Punctate Nuclear 0.0145 0.0075 0.002 0.0038 0.014 0.0119 0.0198 0.004 0.0072 0.0064 0.0071 0.0122 0.0018 0.0037 0.013 0.0093 0.0054 0.0244
Vacuole 0.0031 0.0003 0.0005 0.0016 0.0011 0.0006 0.0075 0.0006 0.0021 0.0006 0.0016 0.0004 0.0019 0.0009 0.0024 0.0009 0.0006 0.0007
Vacuole Periphery 0.0017 0 0.0001 0.0007 0.0008 0.0003 0.0014 0.0001 0.0008 0.0001 0.0022 0.0002 0.0006 0.0001 0.0008 0.0005 0.0002 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.9121 9.3673 11.1215 17.2279 24.4549 38.7496 10.4184 9.9083 13.5141 22.9525
Translational Efficiency 1.2114 1.3663 1.0857 0.9066 0.9766 0.9206 1.1985 1.3244 1.1156 1.2348

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2100 1133 2878 1483 1637 1253 147 857 3737 2386 3025 2340

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 698.92 731.76 778.04 778.70 657.21 712.73 866.89 813.67 680.65 721.77 782.36 791.51
Standard Deviation 73.06 86.13 92.01 104.81 69.35 88.22 89.86 156.57 74.40 87.75 93.87 127.37
Intensity Change Log 2 — 0.066243 0.154717 0.155940 — 0.117001 0.399495 0.308089 — 0.091065 0.278531 0.231680

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000064 0.000331 0.000214 0.001271 0.000080 0.000223 0.000224 0.002824 0.000071 0.000274 0.000215 0.001840
Bud Neck 0.013927 0.032478 0.011442 0.014844 0.011668 0.031780 0.002065 0.013394 0.012937 0.032111 0.010986 0.014313
Bud Site 0.003281 0.015996 0.013472 0.042718 0.001834 0.014305 0.002568 0.063456 0.002647 0.015108 0.012942 0.050313
Cell Periphery 0.000112 0.000140 0.000136 0.000249 0.000151 0.000244 0.000200 0.000289 0.000129 0.000195 0.000139 0.000264
Cytoplasm 0.445887 0.413179 0.362667 0.330049 0.453457 0.373611 0.214046 0.322690 0.449203 0.392400 0.355445 0.327354
Cytoplasmic Foci 0.177626 0.202195 0.004083 0.015930 0.211868 0.172970 0.028098 0.051137 0.192626 0.186848 0.005250 0.028824
Eisosomes 0.000138 0.000110 0.000016 0.000051 0.000182 0.000156 0.000115 0.000075 0.000157 0.000134 0.000021 0.000059
Endoplasmic Reticulum 0.000908 0.000967 0.001540 0.003154 0.000761 0.000855 0.003970 0.002846 0.000843 0.000908 0.001658 0.003041
Endosome 0.005318 0.012815 0.000753 0.005908 0.005711 0.020967 0.003694 0.047942 0.005490 0.017096 0.000896 0.021302
Golgi 0.001127 0.002776 0.000132 0.002700 0.001631 0.004533 0.000088 0.028941 0.001348 0.003699 0.000130 0.012310
Lipid Particles 0.007554 0.004388 0.000434 0.001416 0.009541 0.009534 0.004095 0.005861 0.008425 0.007091 0.000612 0.003044
Mitochondria 0.003410 0.007303 0.001619 0.009769 0.003430 0.012906 0.000340 0.014914 0.003419 0.010245 0.001557 0.011653
Mitotic Spindle 0.002521 0.012305 0.010531 0.058866 0.000877 0.010108 0.000468 0.106057 0.001801 0.011151 0.010042 0.076149
None 0.002991 0.006532 0.004536 0.006762 0.003501 0.004859 0.003862 0.008840 0.003214 0.005653 0.004504 0.007523
Nuclear Periphery 0.000707 0.000639 0.002449 0.003093 0.000542 0.001174 0.002029 0.001986 0.000635 0.000920 0.002428 0.002687
Nuclear Periphery Foci 0.000188 0.000488 0.000189 0.000849 0.000240 0.000303 0.001354 0.004535 0.000211 0.000390 0.000246 0.002199
Nucleolus 0.001134 0.002585 0.000497 0.000770 0.001037 0.004269 0.001640 0.002737 0.001091 0.003469 0.000553 0.001490
Nucleus 0.295861 0.204506 0.561508 0.417689 0.259837 0.240744 0.643106 0.178306 0.280081 0.223536 0.565473 0.330017
Peroxisomes 0.003744 0.016935 0.000228 0.001386 0.005263 0.011615 0.000562 0.005263 0.004409 0.014141 0.000244 0.002806
Vacuole 0.032967 0.061814 0.023250 0.076001 0.027831 0.082437 0.087218 0.117508 0.030717 0.072644 0.026359 0.091203
Vacuole Periphery 0.000536 0.001520 0.000303 0.006526 0.000558 0.002407 0.000257 0.020401 0.000545 0.001986 0.000301 0.011608

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -9.11 -4.45 -6.19 -3.52 -4.23 -4.22 -5.65 -3.72 -3.35 -2.89 -9.03 -4.70 -5.93 -4.63 -4.71
Bud Neck -6.83 1.64 1.85 7.96 0.36 -8.26 8.08 1.23 8.95 -6.34 -10.54 1.53 2.11 11.85 0.51
Bud Site -6.75 -6.07 -6.57 -1.18 -2.79 -6.76 -1.18 -9.25 -5.92 -6.30 -9.34 -7.12 -11.26 -5.02 -6.46
Cell Periphery -2.04 -1.63 -3.77 -1.35 -2.33 -2.57 -1.97 -2.09 1.17 0.06 -3.29 -0.12 -3.92 0.82 -3.31
Cytoplasm 3.70 17.03 22.38 14.51 7.79 8.29 15.26 13.65 5.97 -5.91 8.56 21.57 26.18 14.92 5.80
Cytoplasmic Foci -3.01 41.60 39.30 29.80 -6.47 5.51 32.89 33.04 24.44 -2.57 1.35 58.56 51.94 39.73 -11.27
Eisosomes 2.57 14.25 8.90 6.36 -17.58 1.21 3.40 8.17 3.78 4.79 1.86 18.28 12.15 5.83 -19.91
Endoplasmic Reticulum -0.53 -5.40 -12.54 -15.89 -11.40 -0.71 -7.87 -6.89 -7.00 3.98 -0.70 -9.38 -14.77 -17.25 -8.99
Endosome -6.76 11.14 4.86 9.29 -6.62 -9.14 3.06 -6.11 -0.59 -6.85 -11.33 14.84 -4.26 4.83 -8.86
Golgi -4.01 6.50 0.86 4.06 -2.69 -2.45 6.90 -5.33 -3.58 -6.09 -3.61 9.31 -4.84 -1.68 -6.46
Lipid Particles 5.99 17.00 14.37 8.64 -13.64 0.19 7.13 5.96 4.69 0.35 2.16 20.48 13.08 7.72 -5.39
Mitochondria -3.19 3.82 -0.45 2.50 -2.76 -5.37 6.32 -2.95 2.46 -5.48 -6.24 5.19 -2.31 4.00 -5.14
Mitotic Spindle -4.03 -5.41 -8.54 -4.98 -5.91 -4.89 -0.83 -10.42 -8.79 -10.22 -6.11 -6.52 -13.43 -9.94 -10.37
None -2.30 -2.72 -5.19 -0.12 -3.66 -1.41 -0.06 -2.14 -1.09 -1.87 -2.77 -2.46 -4.84 -0.97 -3.50
Nuclear Periphery 0.37 -22.65 -19.97 -19.94 -6.73 -5.20 -10.62 -9.90 -5.53 1.21 -3.87 -26.53 -22.22 -18.54 -3.72
Nuclear Periphery Foci -3.30 -2.68 -12.23 -3.75 -11.09 -1.46 -5.01 -2.81 -2.73 -0.88 -3.70 -4.06 -4.63 -3.84 -4.23
Nucleolus -3.26 2.66 1.60 4.54 -2.43 -5.53 0.10 -0.94 3.47 -0.90 -6.31 3.53 0.17 6.03 -2.46
Nucleus 10.99 -40.41 -19.52 -26.49 11.86 2.18 -14.61 2.10 0.23 14.88 9.23 -48.64 -14.85 -20.58 24.29
Peroxisomes -8.10 13.61 9.10 10.02 -2.69 -4.64 7.92 3.26 6.70 -3.65 -9.28 13.70 7.66 12.37 -4.76
Vacuole -9.39 -2.05 -21.85 -14.82 -20.85 -14.09 -7.88 -22.22 -14.77 -3.91 -16.66 -6.13 -30.93 -19.99 -27.18
Vacuole Periphery -4.57 3.28 -2.29 -0.78 -2.75 -5.84 5.11 -4.89 -3.83 -5.08 -7.34 4.72 -5.34 -3.44 -5.73
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Third subunit of DNA polymerase delta; involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; forms a complex with Rev3p, Rev7p and Pol31p; interacts with Hys2p, PCNA (Pol30p), and Pol1p
Localization
Cell Percentages cytoplasm (10%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Pol32

Pol32


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pol32-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available