ORF
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0.07 0.06 0.07 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.11 0.18 0.06 0 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0.13 0.11 0.06 0.05 0 0 0 0 0 0 0.09 0 0 0 0 0 0 0 0.05 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0 0.29 0.11 0.05 0.24 0.33 0.27 0.45 0.4 0.52 0.55 0 0 0 0.05 0.12 0.07 0 0 0 0 0 0
Nucleus 0.32 0.24 0.27 0.11 0.13 0.08 0.14 0.12 0.12 0.1 0.1 0.08 0.19 0.11 0.12 0.13 0.14 0.13 0.2 0.18 0.14 0.07 0.05 0.07
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.78 0.81 0.83 0.9 0.82 0.8 0.72 0.68 0.64 0.58 0.52 0.5 0.81 0.83 0.72 0.85 0.86 0.81 0.64 0.68 0.64 0.73 0.61 0.55
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.12 0.1 0.1 0.28 0.37 0.38 0.38 0.38 0.35 0.43 0.3 0.35 0.16 0.17 0.24 0.14 0.08 0.11 0.09 0.08 0.13 0.12 0.21 0.22
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 1 0 1 7 5 20 11 7 19 11 1 1 1 0 0 0 5 0 1 0 1 2
Bud Neck 2 0 0 4 5 5 5 5 3 6 3 3 4 7 6 1 0 0 1 0 2 1 1 2
Bud Site 3 0 6 5 3 10 8 25 18 28 25 29 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0
Cytoplasm 4 3 1 6 15 13 6 26 13 15 8 11 19 25 72 13 7 12 0 0 0 1 0 0
Endoplasmic Reticulum 0 0 1 1 0 0 0 1 0 0 0 0 1 1 0 2 0 1 0 0 0 0 0 0
Endosome 12 0 1 0 45 45 15 36 19 19 14 16 3 6 36 6 5 3 14 1 7 0 9 12
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 2 1
Mitochondria 31 5 61 29 16 96 79 208 214 171 210 232 4 3 4 11 27 11 3 1 0 0 1 1
Nucleus 209 32 58 29 45 33 32 89 56 42 41 35 44 27 47 28 30 20 140 25 29 7 10 17
Nuclear Periphery 3 2 1 0 0 1 0 2 1 0 2 2 0 1 0 1 3 1 0 0 0 0 0 2
Nucleolus 509 109 175 231 284 325 171 521 302 248 209 210 189 194 293 178 190 121 441 97 135 80 126 134
Peroxisomes 0 0 0 5 7 7 1 17 5 7 4 6 0 0 3 0 0 1 0 0 0 0 0 0
SpindlePole 77 14 21 71 130 156 89 295 168 182 119 147 38 40 96 29 18 17 63 11 27 13 43 54
Vac/Vac Membrane 5 1 2 0 2 1 0 3 3 2 7 5 0 2 3 3 5 4 13 3 4 2 5 7
Unique Cell Count 654 135 211 257 347 408 237 769 475 424 402 421 234 235 406 210 221 150 688 143 212 110 209 244
Labelled Cell Count 855 166 328 381 553 699 411 1249 813 727 661 707 303 307 562 273 285 191 688 143 212 110 209 244


Nucleolus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.4 8.7 5.8 7.2 6.4 4.7 4.3 4.3 3.7 3.7 3.5 3.4 8.1 8.0 7.4 14.2 13.6 12.9 8.3 9.8 9.6
Std Deviation (1e-4) 1.5 2.0 1.6 2.2 2.2 1.5 1.7 1.4 1.3 1.1 1.0 1.0 2.1 2.0 2.3 5.2 4.4 4.1 2.1 2.4 2.3
Intensity Change (Log2) – – – 0.31 0.15 -0.29 -0.44 -0.42 -0.65 -0.63 -0.71 -0.75 0.5 0.46 0.35 1.3 1.24 1.16 0.51 0.76 0.74

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 2.6 0 0 2.3 0 2.3 0 0 3.9 4.6 6.3 3.3 0 3.8
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 5.2 0 0 0 0 0 0 0 0 0 4.2 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -4.8 -8.1 0 0 0 0 0 0 0 -8.1 -8.3 -10.7 -6.4 -4.3 -5.1
Nucleus -4.5 -4.3 -6.5 -3.7 -5.7 -5.1 -5.7 -5.5 -6.4 -2.2 -4.3 -5.0 -3.6 -3.6 -3.2
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 2.2 -0.3 0 0 0 0 0 0 0 -0.6 -0.1 -3.0 0.5 0.9 -0.6
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 4.8 7.1 0 0 0 0 0 0 0 2.0 2.2 4.1 1.2 -0.7 0.4
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.097 3.9146 3.5131 2.6384 2.0946 3.2186 3.021 3.6271 3.034 2.9459 2.0923 3.2052 4.4321 4.9207 4.827 4.6959 4.0078 4.5922
Actin 0.0129 0 0 0.0279 0.0008 0 0.0069 0 0.0084 0.0017 0.0051 0.004 0.0204 0 0.0064 0.0001 0.0008 0.0142
Bud 0.0001 0 0 0.0002 0.0004 0 0.0006 0 0.0004 0.0003 0.0059 0.0001 0.0004 0 0.0001 0 0.0001 0
Bud Neck 0.0008 0.0006 0.0007 0.002 0.0016 0.0007 0.0008 0.0002 0.0016 0.0004 0.0024 0.0005 0.0016 0.0008 0.001 0.0006 0.0008 0.0007
Bud Periphery 0.0001 0.0001 0.0001 0.0003 0.0006 0.0001 0.0015 0 0.0004 0.0004 0.0114 0.0001 0.0013 0 0.0001 0 0.0001 0.0001
Bud Site 0.001 0.0003 0.0006 0.001 0.0061 0.0002 0.0024 0.0002 0.0024 0.0007 0.0067 0.0002 0.0015 0.0003 0.0012 0.0004 0.0004 0.0001
Cell Periphery 0.0002 0.0002 0.0002 0.0002 0.0005 0.0001 0.0008 0.0001 0.0001 0.0002 0.0005 0 0.0006 0.0001 0.0002 0.0001 0 0
Cytoplasm 0.0042 0 0 0.0002 0.0172 0 0.0259 0.0125 0.003 0.0004 0.0015 0.0201 0.0022 0 0.0011 0.0008 0.0002 0
Cytoplasmic Foci 0.0261 0.0009 0.0042 0.0149 0.0342 0.0011 0.0121 0.0001 0.0047 0.005 0.0161 0.0039 0.0054 0.0003 0.0069 0.0101 0.0079 0.0011
Eisosomes 0.0001 0 0 0.0002 0.0001 0 0.0002 0 0.0002 0 0.0001 0 0.0005 0 0.0001 0 0 0.0001
Endoplasmic Reticulum 0.0005 0 0 0.0004 0.0032 0 0.0037 0 0.0011 0.0003 0.0016 0.0001 0.0037 0 0.0003 0.0003 0.0002 0.0001
Endosome 0.0078 0.0001 0.0004 0.034 0.0778 0.0001 0.0266 0 0.0148 0.0387 0.0918 0.0058 0.0109 0.0002 0.0041 0.0012 0.0025 0.0009
Golgi 0.0035 0.0001 0.0004 0.0336 0.0059 0.0002 0.0103 0 0.007 0.0154 0.0165 0.0113 0.0025 0 0.0017 0.0004 0.0016 0.0013
Lipid Particles 0.017 0.003 0.0123 0.0684 0.0224 0.007 0.0233 0.0002 0.0083 0.0107 0.0075 0.0054 0.0091 0.0007 0.0061 0.0072 0.0155 0.0057
Mitochondria 0.0086 0.0001 0.0005 0.0172 0.0027 0.0001 0.0282 0 0.0035 0.0246 0.0191 0.0065 0.0022 0.0001 0.0005 0.0002 0.0003 0.0008
None 0.0018 0 0 0.0004 0.042 0 0.0011 0 0.0095 0.0005 0.0006 0 0.005 0 0.0057 0.0013 0.0003 0.0004
Nuclear Periphery 0.0037 0 0.0001 0.0009 0.0071 0.0001 0.0135 0.0001 0.0027 0.0007 0.0038 0.0001 0.0105 0.0002 0.0008 0.0024 0.0036 0.0012
Nucleolus 0.8188 0.8834 0.8933 0.6973 0.6838 0.8981 0.7313 0.8562 0.8189 0.801 0.7044 0.8543 0.7908 0.8332 0.845 0.8788 0.6863 0.8601
Nucleus 0.0536 0.1044 0.0681 0.0583 0.069 0.0724 0.071 0.1256 0.1061 0.0776 0.0609 0.0806 0.0898 0.1409 0.1005 0.0602 0.0496 0.0642
Peroxisomes 0.0031 0.0001 0.003 0.0316 0.0022 0.0004 0.0035 0 0.0023 0.0023 0.003 0.0031 0.0036 0 0.0027 0.0003 0.0017 0.0016
Punctate Nuclear 0.0349 0.006 0.015 0.0079 0.0119 0.0193 0.0256 0.0044 0.0032 0.0023 0.0245 0.0034 0.0348 0.0223 0.0141 0.0346 0.2278 0.0471
Vacuole 0.0009 0.0007 0.0007 0.0014 0.0079 0.0002 0.006 0.0003 0.0008 0.0103 0.0112 0.0002 0.0026 0.0006 0.0012 0.0005 0.0002 0.0001
Vacuole Periphery 0.0003 0.0001 0.0001 0.0016 0.0023 0 0.0045 0 0.0004 0.0063 0.0056 0.0002 0.0009 0.0002 0.0002 0.0003 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 72.8438 70.4554 83.9664 49.5656 68.1244 42.966 43.7139 45.895 38.0267 43.1715
Translational Efficiency 2.4954 2.6885 1.84 2.4293 2.3303 3.0251 1.8621 1.9575 1.792 2.3011

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1254 665 209 1287 1687 196 1924 1766 2941 861 2133 3053

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 742.67 960.40 1144.88 1202.34 821.53 1042.95 1113.52 1235.93 787.91 979.19 1116.59 1221.77
Standard Deviation 134.82 181.28 147.11 243.88 140.91 168.98 188.12 239.71 143.74 181.88 184.74 242.05
Intensity Change Log 2 — 0.370914 0.624403 0.695052 — 0.344285 0.438742 0.589212 — 0.356990 0.529876 0.640433

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000286 0.000437 0.000783 0.000487 0.000238 0.000479 0.000296 0.000433 0.000258 0.000447 0.000344 0.000456
Bud Neck 0.003611 0.006533 0.007841 0.015719 0.003693 0.005848 0.004535 0.013072 0.003658 0.006377 0.004858 0.014188
Bud Site 0.001200 0.001576 0.002020 0.003657 0.000435 0.000923 0.000620 0.003079 0.000761 0.001427 0.000757 0.003322
Cell Periphery 0.000119 0.000047 0.000043 0.000106 0.000056 0.000033 0.000022 0.000135 0.000083 0.000044 0.000024 0.000123
Cytoplasm 0.004233 0.001276 0.000301 0.001314 0.000646 0.000322 0.000237 0.000657 0.002175 0.001059 0.000243 0.000934
Cytoplasmic Foci 0.003253 0.001743 0.000587 0.003377 0.000572 0.000711 0.000370 0.001476 0.001715 0.001508 0.000391 0.002277
Eisosomes 0.000090 0.000085 0.000098 0.000104 0.000076 0.000077 0.000071 0.000126 0.000082 0.000083 0.000073 0.000117
Endoplasmic Reticulum 0.002368 0.001981 0.002906 0.000592 0.001717 0.002382 0.000497 0.000602 0.001994 0.002072 0.000733 0.000598
Endosome 0.002144 0.002676 0.000488 0.003546 0.001173 0.000646 0.000200 0.001322 0.001587 0.002214 0.000228 0.002259
Golgi 0.002705 0.001440 0.001063 0.003228 0.001081 0.001308 0.000360 0.000531 0.001774 0.001410 0.000429 0.001668
Lipid Particles 0.001472 0.001999 0.000413 0.000176 0.000411 0.004492 0.000043 0.000284 0.000864 0.002566 0.000079 0.000238
Mitochondria 0.002905 0.001687 0.000764 0.004269 0.001423 0.001001 0.000973 0.003080 0.002055 0.001531 0.000953 0.003581
Mitotic Spindle 0.007720 0.016612 0.087375 0.050843 0.013308 0.035941 0.018637 0.026830 0.010925 0.021012 0.025372 0.036953
None 0.008632 0.001596 0.000623 0.001074 0.001994 0.000457 0.000401 0.000778 0.004824 0.001337 0.000423 0.000903
Nuclear Periphery 0.000525 0.000533 0.000582 0.001218 0.000568 0.000769 0.000289 0.001151 0.000550 0.000587 0.000318 0.001179
Nuclear Periphery Foci 0.019082 0.007559 0.004976 0.001747 0.009722 0.008094 0.000669 0.001523 0.013713 0.007681 0.001091 0.001617
Nucleolus 0.605442 0.576951 0.596856 0.653934 0.597494 0.564179 0.676373 0.682514 0.600883 0.574044 0.668581 0.670466
Nucleus 0.325959 0.363329 0.270333 0.235313 0.359953 0.361427 0.282840 0.245985 0.345459 0.362896 0.281615 0.241486
Peroxisomes 0.006587 0.009244 0.017150 0.011368 0.004243 0.008824 0.011626 0.010639 0.005242 0.009148 0.012167 0.010946
Vacuole 0.001102 0.001590 0.004227 0.004186 0.000643 0.001478 0.000477 0.003104 0.000839 0.001564 0.000844 0.003560
Vacuole Periphery 0.000563 0.001107 0.000572 0.003743 0.000553 0.000610 0.000466 0.002681 0.000558 0.000994 0.000476 0.003129

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.62 -5.68 -6.80 -2.43 3.60 -4.60 -3.64 -7.88 0.57 -5.65 -4.63 -5.21 -10.32 -1.32 -4.88
Bud Neck -4.48 -8.51 -14.79 -11.37 -9.02 -2.99 -2.80 -11.97 -7.50 -10.87 -5.36 -4.77 -18.75 -12.96 -16.28
Bud Site -1.12 -4.15 -6.11 -4.92 -2.90 -3.49 -3.76 -6.95 -4.85 -6.29 -2.70 -1.46 -9.21 -5.78 -8.93
Cell Periphery 4.05 3.29 -0.01 -4.82 -3.92 1.63 2.70 -2.75 -3.59 -4.02 3.33 5.72 -2.47 -4.64 -5.87
Cytoplasm 1.67 3.22 1.57 -0.22 -2.42 0.91 0.81 -1.23 -2.86 -2.70 0.75 3.33 1.14 0.14 -3.33
Cytoplasmic Foci 1.43 3.70 0.67 -0.88 -3.59 -0.92 0.93 -3.72 -2.60 -4.42 -0.11 4.29 -0.87 -0.56 -5.98
Eisosomes 0.83 -2.51 -1.22 -1.69 1.42 -0.54 2.06 -4.38 -3.70 -5.04 -0.56 3.16 -4.47 -3.66 -5.76
Endoplasmic Reticulum 1.62 -2.81 11.72 7.13 6.14 -2.53 11.19 10.18 6.04 -1.64 -0.78 10.77 15.45 9.28 2.18
Endosome -0.91 3.28 -1.14 0.04 -3.19 1.77 3.39 -0.55 -2.66 -4.50 -1.23 5.14 -1.25 0.59 -5.12
Golgi 1.59 2.52 0.08 -1.24 -1.89 -0.71 3.28 2.42 2.22 -3.05 0.32 5.22 0.88 0.48 -3.49
Lipid Particles -0.36 2.51 3.91 1.38 3.41 -1.03 4.48 0.96 1.06 -2.77 -1.23 5.15 3.92 1.71 -2.74
Mitochondria 1.37 2.61 -1.41 -3.20 -4.66 2.39 2.61 -3.55 -4.63 -4.68 1.14 3.05 -2.98 -4.20 -6.40
Mitotic Spindle -3.33 -6.23 -10.34 -7.13 2.38 -3.27 -2.76 -5.49 1.19 -3.19 -4.06 -6.49 -11.24 -4.61 -4.47
None 5.02 5.94 5.45 0.92 -1.74 3.92 4.02 2.52 -3.08 -3.41 5.02 7.10 5.97 0.96 -4.01
Nuclear Periphery -0.14 -1.34 -4.16 -4.01 -3.76 -1.30 3.44 -3.21 -1.93 -4.91 -0.37 2.98 -5.07 -4.26 -7.23
Nuclear Periphery Foci 4.57 6.42 8.94 4.27 4.73 0.89 8.73 7.56 4.45 -3.57 3.67 12.29 11.65 5.37 -2.33
Nucleolus 3.10 2.23 -1.42 -3.99 -2.90 2.56 -10.44 -8.57 -6.77 0.87 3.83 -9.57 -7.19 -8.61 2.23
Nucleus -3.65 2.67 8.81 10.84 1.99 0.30 10.90 15.64 7.07 4.52 -1.86 10.02 17.48 13.54 5.29
Peroxisomes -2.51 -6.62 -5.56 -1.01 4.21 -4.97 -14.94 -13.13 -0.85 1.49 -4.89 -13.38 -12.59 -0.99 2.45
Vacuole -1.79 -2.43 -5.49 -3.28 0.90 -2.33 0.01 -5.58 -3.24 -5.51 -2.73 -1.45 -7.79 -3.84 -5.94
Vacuole Periphery -2.28 -0.97 -5.60 -4.21 -5.48 -0.71 0.94 -7.42 -7.25 -8.00 -2.44 0.93 -8.92 -6.24 -9.38
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene
Localization
Cell Percentages nucleolus (84%)
Cell Cycle Regulation No
Subcompartmental Group nucleolus-2

YCR087C-A

YCR087C-A


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ycr087c-a-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available