| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Transcriptional activator involved in regulating lysine biosynthesis; involved in the regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Bud | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| Bud Neck | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Bud Site | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | – | – | – |
| Cell Periphery | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cytoplasm | 3 | 2 | – | – | – | – | – | – | – | – | – | – | – | – | – | 16 | 6 | 6 | 1 | 1 | 0 | 0 | 0 | 0 |
| Endoplasmic Reticulum | 1 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 8 | 9 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Endosome | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 6 | 2 | 4 | 2 | 1 | 0 | 2 | 1 | 3 |
| Golgi | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 2 |
| Mitochondria | 3 | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – | 20 | 4 | 17 | 3 | 0 | 0 | 1 | 0 | 2 |
| Nucleus | 13 | 8 | – | – | – | – | – | – | – | – | – | – | – | – | – | 222 | 171 | 109 | 34 | 28 | 10 | 7 | 23 | 25 |
| Nuclear Periphery | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 6 | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 1 |
| Nucleolus | 1 | 5 | – | – | – | – | – | – | – | – | – | – | – | – | – | 19 | 10 | 6 | 6 | 3 | 1 | 2 | 4 | 7 |
| Peroxisomes | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| SpindlePole | 0 | 0 | – | – | – | – | – | – | – | – | – | – | – | – | – | 5 | 1 | 0 | 2 | 0 | 0 | 1 | 1 | 0 |
| Vac/Vac Membrane | 0 | 2 | – | – | – | – | – | – | – | – | – | – | – | – | – | 42 | 19 | 18 | 3 | 10 | 1 | 1 | 9 | 14 |
| Unique Cell Count | 19 | 16 | 307 | 210 | 144 | 61 | 46 | 18 | 19 | 45 | 61 | |||||||||||||
| Labelled Cell Count | 21 | 18 | 345 | 227 | 165 | 61 | 46 | 18 | 19 | 45 | 61 | |||||||||||||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 6.2 | 6.3 | – | – | – | – | – | – | – | – | – | – | – | – | – | 8.5 | 8.9 | 8.4 | – | – | 5.1 |
| Std Deviation (1e-4) | 3.2 | 1.2 | – | – | – | – | – | – | – | – | – | – | – | – | – | 1.8 | 1.6 | 1.8 | – | – | 0.6 |
| Intensity Change (Log2) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | 0.052 | 0.0008 | 0.0004 | 0.0873 | 0.0005 | 0.0015 |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | 0.0009 | 0.0162 | 0.0001 | 0.0005 | 0.0001 | 0.0005 |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | 0.0014 | 0.0005 | 0.0003 | 0.002 | 0.0061 | 0.0064 |
| Bud Periphery | – | – | – | – | – | – | – | – | – | – | – | – | 0.0012 | 0.0051 | 0.0004 | 0.0009 | 0.0002 | 0.0029 |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | 0.0081 | 0.0091 | 0.0003 | 0.0021 | 0.0003 | 0.001 |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | 0.0004 | 0.0007 | 0.0002 | 0.0004 | 0.0001 | 0.0005 |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | 0.0008 | 0.0162 | 0.0005 | 0.0033 | 0.0017 | 0.0003 |
| Cytoplasmic Foci | – | – | – | – | – | – | – | – | – | – | – | – | 0.0261 | 0.0182 | 0 | 0.002 | 0.0002 | 0.0003 |
| Eisosomes | – | – | – | – | – | – | – | – | – | – | – | – | 0.0008 | 0.0001 | 0 | 0.0006 | 0.0001 | 0.0001 |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | 0.0011 | 0.0005 | 0.0002 | 0.0315 | 0.0004 | 0.0006 |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | 0.0158 | 0.0014 | 0.0005 | 0.0137 | 0.0011 | 0.0047 |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | 0.0187 | 0.0002 | 0 | 0.0056 | 0.0002 | 0.0018 |
| Lipid Particles | – | – | – | – | – | – | – | – | – | – | – | – | 0.0341 | 0.0015 | 0.0001 | 0.0057 | 0.0006 | 0.0036 |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | 0.0218 | 0.0059 | 0.0028 | 0.0046 | 0.0007 | 0.0219 |
| None | – | – | – | – | – | – | – | – | – | – | – | – | 0.0015 | 0.005 | 0.0004 | 0.002 | 0.0007 | 0.0003 |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | 0.0071 | 0.0113 | 0.0388 | 0.104 | 0.0854 | 0.0239 |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | 0.085 | 0.1785 | 0.1298 | 0.1871 | 0.1997 | 0.2066 |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | 0.6411 | 0.7126 | 0.8031 | 0.3824 | 0.6188 | 0.706 |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | 0.018 | 0.0005 | 0.0001 | 0.0006 | 0.0001 | 0.0006 |
| Punctate Nuclear | – | – | – | – | – | – | – | – | – | – | – | – | 0.023 | 0.0088 | 0.0157 | 0.1594 | 0.0801 | 0.006 |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | 0.0248 | 0.0046 | 0.0028 | 0.0016 | 0.0011 | 0.0048 |
| Vacuole Periphery | – | – | – | – | – | – | – | – | – | – | – | – | 0.0161 | 0.0024 | 0.0034 | 0.0026 | 0.0017 | 0.0057 |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 26.969 | 22.446 | 19.1234 | 33.4406 | 30.445 | 26.0246 | 31.8362 | 35.0321 | 36.4248 | 44.4727 |
| Translational Efficiency | 0.2009 | 0.2506 | 0.324 | 0.1904 | 0.2378 | 0.2776 | 0.1954 | 0.2008 | 0.2015 | 0.1833 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | ✘ |
| Gene Expression | ✘ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 158 | 91 | 1751 | 1184 | 174 | 84 | 456 | 237 | 332 | 175 | 2207 | 1421 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 693.42 | 857.00 | 909.23 | 842.26 | 732.40 | 845.74 | 835.13 | 924.96 | 713.85 | 851.60 | 893.92 | 856.05 |
| Standard Deviation | 85.87 | 118.97 | 149.23 | 141.18 | 103.63 | 141.67 | 127.86 | 114.12 | 97.56 | 130.48 | 148.14 | 140.46 |
| Intensity Change Log 2 | — | 0.305566 | 0.390916 | 0.280536 | — | 0.207582 | 0.189369 | 0.336759 | — | 0.256066 | 0.290906 | 0.309690 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000431 | 0.002012 | 0.000781 | 0.002247 | 0.001196 | 0.001674 | 0.000965 | 0.002518 | 0.000832 | 0.001850 | 0.000819 | 0.002292 |
| Bud Neck | 0.003807 | 0.015444 | 0.016664 | 0.030994 | 0.004412 | 0.005750 | 0.011297 | 0.034444 | 0.004124 | 0.010791 | 0.015555 | 0.031569 |
| Bud Site | 0.001525 | 0.002831 | 0.001736 | 0.007544 | 0.002824 | 0.001976 | 0.006402 | 0.006051 | 0.002206 | 0.002421 | 0.002700 | 0.007295 |
| Cell Periphery | 0.000188 | 0.000125 | 0.000170 | 0.000251 | 0.000211 | 0.000119 | 0.000245 | 0.000157 | 0.000200 | 0.000122 | 0.000186 | 0.000235 |
| Cytoplasm | 0.033822 | 0.006386 | 0.023954 | 0.015764 | 0.020268 | 0.004098 | 0.026665 | 0.005146 | 0.026719 | 0.005288 | 0.024514 | 0.013993 |
| Cytoplasmic Foci | 0.017581 | 0.007205 | 0.000834 | 0.005393 | 0.006202 | 0.010252 | 0.005388 | 0.001047 | 0.011617 | 0.008667 | 0.001775 | 0.004668 |
| Eisosomes | 0.000066 | 0.000085 | 0.000036 | 0.000054 | 0.000058 | 0.000099 | 0.000054 | 0.000053 | 0.000062 | 0.000092 | 0.000040 | 0.000054 |
| Endoplasmic Reticulum | 0.003456 | 0.011265 | 0.003884 | 0.007922 | 0.005285 | 0.009578 | 0.005037 | 0.009714 | 0.004415 | 0.010455 | 0.004122 | 0.008221 |
| Endosome | 0.001024 | 0.004449 | 0.000496 | 0.006127 | 0.000901 | 0.010042 | 0.005374 | 0.000988 | 0.000959 | 0.007134 | 0.001504 | 0.005270 |
| Golgi | 0.000661 | 0.001507 | 0.000185 | 0.003458 | 0.000444 | 0.004246 | 0.001487 | 0.001464 | 0.000547 | 0.002822 | 0.000454 | 0.003125 |
| Lipid Particles | 0.004874 | 0.003847 | 0.000275 | 0.001966 | 0.001783 | 0.009875 | 0.001003 | 0.000746 | 0.003254 | 0.006740 | 0.000425 | 0.001763 |
| Mitochondria | 0.003127 | 0.016314 | 0.001277 | 0.007517 | 0.007318 | 0.010028 | 0.003288 | 0.003714 | 0.005324 | 0.013297 | 0.001692 | 0.006883 |
| Mitotic Spindle | 0.000281 | 0.013107 | 0.007591 | 0.042536 | 0.006985 | 0.009276 | 0.006630 | 0.060519 | 0.003795 | 0.011268 | 0.007392 | 0.045535 |
| None | 0.024281 | 0.006780 | 0.014141 | 0.012385 | 0.012574 | 0.006526 | 0.015102 | 0.007751 | 0.018145 | 0.006658 | 0.014339 | 0.011612 |
| Nuclear Periphery | 0.001385 | 0.002783 | 0.001038 | 0.004173 | 0.001038 | 0.001165 | 0.001634 | 0.002760 | 0.001203 | 0.002006 | 0.001161 | 0.003937 |
| Nuclear Periphery Foci | 0.003253 | 0.005483 | 0.000978 | 0.005890 | 0.004233 | 0.008777 | 0.001000 | 0.005010 | 0.003767 | 0.007064 | 0.000983 | 0.005743 |
| Nucleolus | 0.111608 | 0.117313 | 0.080528 | 0.192853 | 0.091685 | 0.105107 | 0.065834 | 0.216276 | 0.101167 | 0.111454 | 0.077492 | 0.196760 |
| Nucleus | 0.783492* | 0.773028* | 0.842160* | 0.640272* | 0.828754* | 0.783991* | 0.834027* | 0.635407* | 0.807213* | 0.778290* | 0.840480* | 0.639460* |
| Peroxisomes | 0.003501 | 0.004950 | 0.000356 | 0.002137 | 0.002429 | 0.004454 | 0.001361 | 0.001538 | 0.002939 | 0.004712 | 0.000564 | 0.002037 |
| Vacuole | 0.001249 | 0.004362 | 0.002741 | 0.007358 | 0.001135 | 0.010554 | 0.005931 | 0.003983 | 0.001189 | 0.007335 | 0.003400 | 0.006795 |
| Vacuole Periphery | 0.000389 | 0.000724 | 0.000176 | 0.003159 | 0.000264 | 0.002411 | 0.001276 | 0.000715 | 0.000324 | 0.001534 | 0.000403 | 0.002751 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -3.15 | -6.98 | -7.85 | -0.39 | -4.71 | -1.36 | -0.05 | -3.38 | -1.27 | -4.23 | -2.95 | -2.00 | -5.77 | -0.72 | -5.89 |
| Bud Neck | -2.78 | -13.56 | -14.52 | -3.50 | -5.68 | -1.01 | -4.71 | -9.46 | -4.82 | -6.58 | -2.70 | -15.66 | -17.51 | -5.82 | -7.86 |
| Bud Site | -1.51 | -2.64 | -6.22 | -2.96 | -5.22 | 0.33 | -1.12 | -2.10 | -2.32 | -1.22 | -0.80 | -1.65 | -5.44 | -4.54 | -4.69 |
| Cell Periphery | 1.49 | 1.44 | -0.74 | -2.73 | -3.55 | 1.13 | -0.04 | 0.92 | -0.56 | 2.26 | 1.70 | 1.12 | -0.06 | -3.25 | -2.64 |
| Cytoplasm | 3.74 | 2.37 | 2.90 | -2.17 | 1.44 | 2.18 | -0.43 | 3.04 | 0.90 | 4.78 | 4.23 | 1.83 | 3.31 | -2.03 | 2.95 |
| Cytoplasmic Foci | 1.74 | 2.99 | 2.44 | 0.99 | -3.68 | -0.71 | 0.93 | 2.24 | 2.75 | 2.43 | 0.96 | 3.45 | 2.86 | 2.27 | -2.31 |
| Eisosomes | -0.87 | 3.20 | 1.92 | 2.32 | -3.46 | -2.26 | 0.40 | 0.02 | 2.37 | -0.52 | -2.36 | 3.29 | 1.76 | 3.49 | -3.19 |
| Endoplasmic Reticulum | -3.42 | -2.82 | -5.68 | 1.36 | -5.04 | -2.46 | -0.83 | -3.20 | 0.23 | -2.75 | -4.16 | -2.05 | -5.78 | 1.53 | -5.64 |
| Endosome | -1.29 | 1.20 | -4.21 | -0.18 | -4.94 | -2.03 | -2.09 | -0.48 | 2.00 | 2.02 | -2.40 | -1.17 | -4.38 | 1.16 | -3.41 |
| Golgi | -0.88 | 1.85 | -2.28 | -1.17 | -3.04 | -1.65 | -1.39 | -1.34 | 1.25 | -0.03 | -1.86 | 0.71 | -2.69 | 0.27 | -2.90 |
| Lipid Particles | 0.63 | 3.32 | 2.48 | 1.40 | -2.42 | -1.82 | 1.90 | 2.44 | 2.11 | 0.89 | -1.40 | 4.06 | 2.67 | 2.36 | -2.21 |
| Mitochondria | -1.30 | 2.54 | -3.14 | 0.92 | -5.42 | -0.52 | 0.85 | 0.68 | 1.82 | -0.78 | -1.33 | 1.31 | -0.35 | 1.29 | -5.34 |
| Mitotic Spindle | -1.99 | -7.89 | -11.15 | -2.90 | -7.37 | -0.53 | -0.43 | -4.95 | -4.74 | -4.97 | -1.88 | -3.25 | -10.10 | -5.67 | -8.91 |
| None | 2.58 | 2.24 | 2.27 | -1.00 | 0.14 | 0.62 | -0.01 | 2.68 | 1.10 | 2.54 | 2.50 | 2.23 | 2.67 | -0.27 | 0.96 |
| Nuclear Periphery | -2.02 | -0.52 | -3.78 | -1.92 | -4.33 | -0.40 | -1.08 | -3.64 | -3.31 | -1.76 | -2.09 | -1.43 | -4.93 | -3.43 | -4.57 |
| Nuclear Periphery Foci | -1.37 | 1.41 | -1.26 | 1.05 | -4.93 | -0.85 | 1.30 | -0.36 | 0.69 | -1.73 | -1.59 | 2.30 | -1.03 | 1.28 | -5.10 |
| Nucleolus | 0.41 | 0.67 | -5.54 | -5.71 | -11.05 | -0.21 | 1.51 | -5.66 | -4.71 | -7.98 | 0.08 | 0.54 | -8.57 | -7.62 | -13.43 |
| Nucleus | 0.27 | -1.40 | 6.93 | 4.92 | 16.78 | 1.46 | -0.17 | 7.84 | 4.29 | 9.59 | 1.31 | -0.62 | 11.12 | 6.55 | 19.28 |
| Peroxisomes | -0.34 | 3.56 | 1.92 | 1.62 | -3.44 | -1.79 | 1.52 | 0.73 | 2.23 | -1.41 | -1.53 | 4.22 | 1.85 | 2.70 | -3.55 |
| Vacuole | -2.14 | -4.70 | -6.13 | -1.83 | -2.49 | -2.39 | -3.38 | -4.51 | 1.05 | -0.02 | -2.99 | -5.89 | -7.12 | 0.09 | -2.28 |
| Vacuole Periphery | -1.40 | 1.12 | -3.32 | -2.65 | -3.69 | -2.19 | -2.13 | -4.92 | 1.71 | 0.91 | -2.48 | -0.79 | -3.63 | -0.78 | -3.44 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Transcriptional activator involved in regulating lysine biosynthesis; involved in the regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer |
| Localization | |
| Cell Percentages | nucleus (93%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | nucleus-3 |
Lys14
Lys14
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Lys14-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
