Standard name
Human Ortholog
Description Predicted membrane protein required for lumenal ER protein retention; mutants secrete the endogenous ER protein, BiP (Kar2p)
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0.15 0.05 0 0 0.05 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0.06 0.08 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.7 0.82 0.69 0.73 0.74 0.75 0.66 0.7 – 0.7 0.67 0.59 0.87 0.82 0.84 0.2 0.33 0.37 0.24 0.4 0.34 0.26 0.32 0.36
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0.09 0 0 0 0 0 0 0
Endosome 0.05 0 0 0.05 0.08 0 0 0 – 0 0 0 0 0.09 0.11 0.36 0.22 0.2 0.19 0.09 0.13 0.11 0.07 0.06
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Mitochondria 0.26 0.17 0.3 0.25 0.23 0.39 0.53 0.42 – 0.43 0.53 0.6 0.05 0 0 0.29 0.16 0.13 0.34 0.31 0.33 0.42 0.42 0.33
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.07 0.15 0 0.06 0 0 0 0 0 0
SpindlePole 0 0 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0.2 0.11 0.15 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0.05 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 2 0 0 0 0 0 0 – 0 0 0 1 1 0 10 24 7 3 5 13 2 6 6
Bud 1 2 4 8 13 21 16 20 – 17 10 15 2 4 3 10 9 10 1 1 4 3 2 4
Bud Neck 0 0 1 1 0 6 4 0 – 2 4 5 1 7 1 0 3 1 0 0 1 0 1 6
Bud Site 0 0 0 1 0 1 9 1 – 2 4 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 3 0 0 1 0 – 1 1 3 0 0 2 3 6 2 0 0 0 0 0 1
Cytoplasm 59 98 162 212 275 382 428 401 – 367 340 389 89 220 263 34 53 49 35 59 89 30 90 94
Endoplasmic Reticulum 0 5 4 1 2 1 2 0 – 0 0 2 3 2 1 8 15 5 2 3 4 1 5 8
Endosome 4 0 5 14 29 3 0 1 – 1 1 0 1 24 33 60 36 26 29 13 34 12 18 14
Golgi 0 1 0 0 0 0 0 0 – 0 0 0 0 0 0 5 6 7 6 5 9 3 5 3
Mitochondria 22 21 70 72 84 202 343 242 – 225 271 391 5 5 8 49 26 17 50 46 88 48 119 85
Nucleus 1 0 1 0 2 1 4 8 – 5 0 4 0 1 1 1 1 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 1 2 – 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 1 1 0 0 1 1 – 0 1 1 0 0 0 0 1 0 0 0 0 0 0 1
Peroxisomes 0 0 0 12 8 3 0 0 – 2 2 0 0 7 21 26 2 8 3 0 4 2 3 1
SpindlePole 0 0 9 18 16 14 18 15 – 13 17 16 1 6 5 33 18 19 3 0 3 1 8 5
Vac/Vac Membrane 2 3 2 2 7 2 3 0 – 6 1 3 1 5 2 5 4 8 5 6 6 4 14 18
Unique Cell Count 84 120 236 290 371 512 645 571 523 507 654 102 268 313 168 163 131 149 148 266 117 286 260
Labelled Cell Count 92 132 259 345 436 636 830 691 642 652 832 104 282 340 244 204 159 149 148 266 117 286 260


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 4.7 3.6 3.7 3.8 3.2 2.9 3.3 – 2.7 2.7 2.5 4.8 5.1 5.3 6.5 6.5 6.6 5.8 5.6 5.8
Std Deviation (1e-4) 0.7 0.9 1.1 2.1 1.6 1.1 1.3 2.0 – 1.2 1.2 0.7 0.7 1.3 1.5 1.0 1.3 1.7 2.1 1.9 2.0
Intensity Change (Log2) – – – 0.06 0.08 -0.15 -0.33 -0.13 – -0.4 -0.43 -0.49 0.43 0.51 0.57 0.87 0.85 0.89 0.69 0.64 0.69


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.1803 -0.0693 -0.0153 -0.1003 0.505 0.017 1.417 1.5052 1.7481 1.1271 1.3389 1.668 -1.2561 -0.4931 -0.5932 -0.208 -0.4757 -0.7644
Actin 0.0291 0.011 0.0082 0.004 0.0229 0.0125 0.0158 0.007 0.0039 0.0255 0.0134 0.0116 0.0039 0.0014 0.0378 0.0291 0.0176 0.0021
Bud 0.0016 0.0018 0.0029 0.0011 0.0081 0.0006 0.0007 0.0003 0.0005 0.0008 0.0003 0.0013 0.0001 0.0001 0.0006 0.0005 0.0003 0.0001
Bud Neck 0.0015 0.0004 0.0007 0.0008 0.0007 0.0009 0.0032 0.0005 0.0006 0.0091 0.0015 0.002 0.0005 0.0001 0.0004 0.0013 0.0004 0.0004
Bud Periphery 0.0037 0.0041 0.0054 0.001 0.0072 0.0007 0.0013 0.0003 0.0013 0.0013 0.0005 0.0028 0.0001 0.0001 0.0006 0.0008 0.0004 0.0001
Bud Site 0.0039 0.0032 0.0075 0.004 0.0041 0.0005 0.0038 0.0063 0.0014 0.0131 0.001 0.0004 0.0009 0.0009 0.0026 0.0011 0.0005 0.0001
Cell Periphery 0.0006 0.0006 0.0005 0.0002 0.0004 0.0002 0.0014 0.0004 0.0003 0.0003 0.0003 0.0002 0.0002 0.0004 0.0006 0.0003 0.0001 0.0001
Cytoplasm 0.0714 0.112 0.0738 0.0232 0.0345 0.0815 0.0966 0.103 0.1024 0.0916 0.1339 0.13 0.0816 0.092 0.1564 0.0774 0.2613 0.1058
Cytoplasmic Foci 0.1463 0.1453 0.1504 0.1079 0.1122 0.1517 0.1459 0.1699 0.1648 0.1117 0.2048 0.1649 0.1596 0.1425 0.1151 0.0763 0.1206 0.163
Eisosomes 0.001 0.001 0.0009 0.0006 0.0008 0.0003 0.0038 0.0004 0.0006 0.0003 0.0002 0.0003 0.0005 0.0003 0.0008 0.0004 0.0003 0.0001
Endoplasmic Reticulum 0.0047 0.0048 0.0038 0.0018 0.0033 0.0028 0.0052 0.0024 0.0038 0.0025 0.0026 0.002 0.0106 0.0041 0.0143 0.003 0.0025 0.0038
Endosome 0.1363 0.1167 0.1461 0.1456 0.2606 0.1607 0.1207 0.1968 0.1519 0.1212 0.1897 0.1212 0.1991 0.1504 0.146 0.1786 0.2809 0.1328
Golgi 0.0374 0.0243 0.0367 0.05 0.0598 0.0358 0.0508 0.0492 0.0491 0.0278 0.058 0.036 0.0453 0.04 0.0441 0.0398 0.1469 0.0361
Lipid Particles 0.0494 0.023 0.0215 0.0199 0.0968 0.039 0.0233 0.0034 0.0135 0.0406 0.0112 0.0177 0.0321 0.0066 0.0252 0.0398 0.0062 0.0426
Mitochondria 0.0286 0.0228 0.0339 0.0525 0.0856 0.0249 0.0216 0.0084 0.015 0.0459 0.0105 0.0104 0.0033 0.0016 0.0172 0.0746 0.0092 0.0188
None 0.4226 0.4902 0.4304 0.5208 0.212 0.3929 0.4559 0.4202 0.453 0.4644 0.3171 0.4554 0.4217 0.5482 0.4026 0.4281 0.1309 0.4553
Nuclear Periphery 0.004 0.0013 0.0018 0.0016 0.0083 0.0021 0.0025 0.0005 0.0016 0.0012 0.0007 0.0009 0.0086 0.0007 0.0015 0.0021 0.0011 0.0008
Nucleolus 0.0012 0.0009 0.0012 0.0011 0.0031 0.0028 0.0009 0.0002 0.0006 0.0004 0.0002 0.0002 0.0005 0.0003 0.0002 0.0002 0.0001 0.0001
Nucleus 0.0019 0.0026 0.0017 0.0036 0.0031 0.0035 0.0007 0.0003 0.0008 0.0008 0.0005 0.0007 0.0024 0.0004 0.0007 0.0006 0.0003 0.0004
Peroxisomes 0.0408 0.0237 0.0521 0.048 0.0547 0.0685 0.0401 0.0263 0.0259 0.0341 0.0467 0.0359 0.0205 0.0047 0.0225 0.007 0.0159 0.0311
Punctate Nuclear 0.0047 0.0021 0.0069 0.0064 0.0081 0.0119 0.0017 0.0006 0.0039 0.0016 0.0028 0.0021 0.0042 0.0013 0.0014 0.0006 0.0005 0.0016
Vacuole 0.0072 0.0066 0.0104 0.0042 0.0086 0.0041 0.0031 0.0024 0.0037 0.0039 0.0031 0.0029 0.0033 0.0033 0.0077 0.0286 0.0023 0.0031
Vacuole Periphery 0.0023 0.0016 0.0032 0.0016 0.0051 0.0021 0.0011 0.0011 0.0013 0.0019 0.0009 0.001 0.001 0.0007 0.0017 0.0099 0.0018 0.0015

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.8373 14.4922 6.049 13.3358 16.4212 18.228 13.2793 12.9804 11.2928 21.655
Translational Efficiency 0.5461 0.5893 0.9246 0.331 0.493 0.7942 0.6626 0.4545 0.5169 0.3663

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1757 1622 985 1252 2075 936 1396 1348 3832 2558 2381 2600

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 673.86 726.42 829.58 794.59 693.34 721.47 794.72 799.80 684.41 724.61 809.14 797.29
Standard Deviation 79.99 97.24 101.48 113.51 86.49 90.76 92.35 118.79 84.14 94.95 97.75 116.31
Intensity Change Log 2 — 0.108355 0.299932 0.237762 — 0.057376 0.196884 0.206076 — 0.082728 0.248594 0.221780

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000335 0.000639 0.000310 0.001563 0.000493 0.001023 0.000447 0.000546 0.000421 0.000779 0.000390 0.001035
Bud Neck 0.012413 0.023848 0.003618 0.013470 0.015704 0.029702 0.004171 0.010535 0.014195 0.025990 0.003942 0.011948
Bud Site 0.004780 0.012793 0.007877 0.071016 0.004723 0.010360 0.009653 0.042493 0.004749 0.011902 0.008918 0.056228
Cell Periphery 0.000134 0.000151 0.000117 0.000330 0.000084 0.000199 0.000113 0.000229 0.000107 0.000168 0.000115 0.000277
Cytoplasm 0.288231* 0.274844* 0.403761* 0.472545* 0.224538* 0.218858* 0.433568* 0.527769* 0.253742* 0.254358* 0.421237* 0.501177*
Cytoplasmic Foci 0.436759* 0.395117* 0.029450 0.019560 0.454402* 0.430838* 0.034913 0.040886 0.446312* 0.408188* 0.032653 0.030617
Eisosomes 0.000314 0.000213 0.000039 0.000046 0.000347 0.000393 0.000043 0.000054 0.000332 0.000279 0.000041 0.000050
Endoplasmic Reticulum 0.001781 0.001389 0.003864 0.002105 0.002081 0.000809 0.001929 0.001111 0.001944 0.001177 0.002730 0.001590
Endosome 0.027981 0.042051 0.004689 0.006394 0.051077 0.061710 0.004112 0.008625 0.040487 0.049245 0.004351 0.007550
Golgi 0.043219 0.044135 0.000404 0.006329 0.058222 0.048225 0.000695 0.004969 0.051343 0.045632 0.000574 0.005624
Lipid Particles 0.038026 0.019598 0.002411 0.001053 0.043012 0.022580 0.003081 0.001204 0.040726 0.020689 0.002804 0.001131
Mitochondria 0.013229 0.033584 0.000587 0.004184 0.021847 0.036446 0.000788 0.003812 0.017895 0.034631 0.000705 0.003992
Mitotic Spindle 0.004356 0.007913 0.010374 0.040676 0.002873 0.004121 0.006085 0.016003 0.003553 0.006525 0.007859 0.027884
None 0.003631 0.003151 0.005413 0.009162 0.000808 0.000996 0.004490 0.008379 0.002102 0.002362 0.004872 0.008756
Nuclear Periphery 0.000418 0.000465 0.002017 0.001372 0.000371 0.000173 0.001529 0.000972 0.000393 0.000358 0.001731 0.001165
Nuclear Periphery Foci 0.000673 0.000550 0.002554 0.001063 0.000314 0.000189 0.001113 0.000579 0.000479 0.000418 0.001709 0.000812
Nucleolus 0.001193 0.001256 0.000758 0.000671 0.001295 0.000765 0.000673 0.000443 0.001248 0.001077 0.000708 0.000553
Nucleus 0.070800 0.055378 0.465290* 0.239833* 0.044644 0.037917 0.441483* 0.237188* 0.056637 0.048989 0.451332* 0.238462*
Peroxisomes 0.020255 0.025156 0.001128 0.003547 0.021721 0.041808 0.002753 0.002515 0.021049 0.031249 0.002081 0.003012
Vacuole 0.029589 0.052613 0.054976 0.102381 0.048663 0.048889 0.048038 0.088860 0.039918 0.051250 0.050908 0.095371
Vacuole Periphery 0.001883 0.005156 0.000364 0.002699 0.002781 0.004001 0.000322 0.002828 0.002369 0.004734 0.000340 0.002766

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.14 -1.00 -3.15 -1.64 -2.90 -2.82 0.87 0.90 3.11 -0.16 -4.28 0.37 -2.59 0.59 -2.58
Bud Neck -6.86 9.13 1.65 7.27 -4.76 -5.62 10.58 5.22 8.27 -3.63 -8.42 13.81 4.96 11.18 -5.87
Bud Site -5.83 -1.35 -8.27 -6.07 -7.39 -4.73 -2.07 -7.63 -5.45 -6.10 -8.00 -2.43 -11.26 -8.01 -9.52
Cell Periphery -0.82 0.83 -2.09 -1.54 -2.71 -8.04 -5.06 -5.99 1.35 -3.69 -5.28 -1.55 -4.90 -0.83 -4.32
Cytoplasm 1.35 -6.61 -7.95 -9.01 -0.86 0.57 -17.98 -23.32 -20.86 -5.75 -0.20 -17.51 -22.24 -20.33 -4.42
Cytoplasmic Foci 5.10 64.03 69.33* 60.80 4.47 2.56 75.93* 77.45* 51.77 -1.03 6.36 98.83 104.08 78.26 2.02
Eisosomes 4.55 13.50 12.89 13.37 -3.90 -1.52 15.96 15.24 13.31 -4.45 3.01 20.89 19.96 18.50 -5.90
Endoplasmic Reticulum 1.21 -8.17 -4.31 -7.72 5.74 3.32 -1.91 0.76 -5.59 5.61 2.96 -6.53 -2.06 -8.52 7.26
Endosome -5.83 16.00 16.82 19.36 2.13 -2.84 24.66 22.28 16.90 -2.06 -4.09 29.11 27.60 25.15 -0.73
Golgi -0.12 17.80 15.92 14.89 -2.19 2.29 20.93 19.35 13.10 -2.59 2.15 27.35 24.99 19.81 -3.35
Lipid Particles 7.82 17.66 18.41 13.99 5.43 8.34 20.76 21.81 13.82 4.52 11.83 27.22 28.53 19.36 6.46
Mitochondria -8.30 13.81 11.26 13.76 -4.08 -4.05 15.05 13.31 10.22 -3.17 -8.05 19.78 17.12 17.09 -4.89
Mitotic Spindle -2.24 -2.68 -6.73 -5.55 -4.02 -1.06 -2.05 -4.46 -3.37 -2.52 -2.89 -3.30 -8.05 -6.08 -5.01
None 0.56 -1.07 -2.48 -2.86 -1.71 -0.84 -11.69 -4.75 -4.48 -1.63 -0.48 -5.29 -5.24 -4.52 -2.44
Nuclear Periphery -0.52 -14.25 -12.87 -13.24 -0.66 4.40 -17.44 -8.89 -10.96 3.84 0.48 -22.06 -15.60 -16.08 1.89
Nuclear Periphery Foci 0.57 -7.41 -3.02 -4.77 5.98 4.28 -6.52 -6.45 -9.03 3.67 0.56 -9.41 -5.08 -6.33 6.63
Nucleolus -0.25 0.49 2.99 3.99 1.29 2.10 1.40 3.52 4.31 1.67 1.19 1.46 4.49 6.04 2.00
Nucleus 3.74 -41.30 -28.82 -30.48 15.90 2.03 -53.73 -32.92 -32.47 18.62 2.71 -67.29 -43.78 -43.79 24.44
Peroxisomes -2.83 17.05 15.36 16.93 -0.54 -6.59 17.10 17.66 13.86 0.78 -6.60 23.82 23.38 21.46 0.39
Vacuole -9.36 -11.62 -25.71 -21.81 -16.02 0.09 -6.57 -18.78 -17.69 -13.03 -5.55 -12.77 -31.34 -27.87 -20.73
Vacuole Periphery -6.32 9.68 2.46 7.06 -2.49 -3.33 13.20 2.17 3.92 -2.39 -6.63 16.34 3.13 7.42 -3.28
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Predicted membrane protein required for lumenal ER protein retention; mutants secrete the endogenous ER protein, BiP (Kar2p)
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Erd1

Erd1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Erd1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available