Standard name
Human Ortholog
Description Non-essential conserved protein with a role in mRNA decapping; specifically affects the function of the decapping enzyme Dcp1p; mediates decay of the RPS28B mRNA via binding to both Rps28Bp (or Rps28Ap) and the RPS28B mRNA; mediates decay of the YRA1 mRNA by a different, translation-independent mechanism; localizes to cytoplasmic mRNA processing bodies; forms cytoplasmic foci upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.15 0.24 0.27 0.17 0.09 0.05 0 0.05 0.08 0 0.06 0 0 0 0 0.15 0.14 0.17 0.12 0.09 0.19 0.08 0.09 0.1
Bud 0.05 0 0.06 0.11 0.07 0.06 0 0 0 0 0 0 0.1 0.09 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.4 0.38 0.16 0.13 0.2 0.15 0.15 0.09 0.12 0.14 0.14 0.15 0.09 0.08 0.11 0.27 0.26 0.33 0.1 0.12 0 0.05 0.05 0
Endoplasmic Reticulum 0.13 0.37 0.3 0.17 0.09 0.18 0.17 0.1 0.22 0.2 0.16 0.18 0 0 0 0 0.06 0.07 0.17 0.22 0.12 0.15 0.13 0
Endosome 0.12 0 0.05 0.06 0.15 0.12 0.07 0.07 0 0 0 0 0.22 0.25 0.29 0.22 0.18 0.16 0.09 0.08 0.05 0.06 0.14 0.18
Golgi 0.14 0.22 0.35 0.37 0.24 0 0.08 0.06 0.06 0 0.05 0 0 0 0.06 0.29 0.39 0.26 0.38 0.37 0.52 0.52 0.48 0.56
Mitochondria 0.28 0 0.28 0.53 0.41 0.64 0.64 0.71 0.79 0.8 0.81 0.77 0 0 0 0.08 0.05 0.1 0.08 0.05 0.06 0.09 0.05 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0.63 0.61 0.6 0 0 0 0 0 0 0 0 0.05
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0.39 0.37 0.4 0.11 0.09 0.05 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.06 0.09 0 0 0 0 0 0 0 0.08 0.2 0.13 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 46 128 84 45 26 23 17 29 31 9 14 7 6 10 4 36 30 22 46 56 72 15 31 27
Bud 15 14 19 29 20 24 11 23 15 12 4 8 26 38 9 5 0 5 3 6 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 1 3 0 0 0 0 1 4 0 0 0 0
Bud Site 0 0 0 0 0 0 0 3 0 0 0 0 0 1 0 0 0 0 – – – – – –
Cell Periphery 3 10 2 3 4 7 7 14 13 7 8 3 0 1 1 5 1 2 0 0 1 0 0 0
Cytoplasm 124 205 49 35 60 64 76 50 44 69 30 35 24 33 48 68 54 44 39 74 11 9 15 3
Endoplasmic Reticulum 40 197 93 45 27 77 83 58 80 97 35 42 0 0 1 7 13 9 68 137 44 27 45 11
Endosome 38 15 17 15 43 50 34 42 5 8 0 1 57 110 124 55 37 21 36 47 17 11 47 52
Golgi 42 120 111 98 71 16 40 32 21 15 10 8 9 18 24 73 81 34 154 232 200 97 164 159
Mitochondria 85 15 88 140 120 270 321 407 291 384 176 181 7 18 3 19 10 13 31 28 21 16 17 6
Nucleus 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 1 0 0 0 0 0 2 0 0
Nuclear Periphery 0 0 0 0 0 2 3 5 5 4 3 2 0 0 0 0 0 0 1 0 1 0 0 1
Nucleolus 1 0 0 0 2 2 2 5 0 2 0 1 7 11 12 1 0 2 0 0 0 0 0 0
Peroxisomes 1 0 5 3 8 5 5 9 1 0 0 0 163 268 253 6 0 1 1 2 4 0 6 15
SpindlePole 0 0 2 1 1 4 2 1 0 1 1 0 100 164 170 27 19 6 0 0 0 0 0 0
Vac/Vac Membrane 9 9 3 2 10 18 29 50 12 15 6 8 2 3 7 20 41 17 13 30 1 2 4 3
Unique Cell Count 308 534 313 264 296 422 502 575 368 483 216 234 259 438 424 248 210 133 402 626 382 188 341 285
Labelled Cell Count 404 713 473 416 392 562 630 729 518 625 287 296 402 678 656 323 286 176 402 626 382 188 341 285


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.1 11.5 10.0 9.4 9.2 8.5 8.0 7.8 7.9 7.5 7.3 7.5 10.2 10.1 10.5 11.8 13.4 13.3 9.3 9.4 10.3
Std Deviation (1e-4) 1.1 1.6 1.5 1.6 1.7 3.5 1.8 1.8 1.7 1.6 1.7 1.8 2.0 2.3 2.1 2.6 2.7 2.9 1.4 1.6 1.6
Intensity Change (Log2) – – – -0.08 -0.11 -0.23 -0.32 -0.35 -0.34 -0.42 -0.45 -0.4 0.03 0.02 0.07 0.25 0.43 0.41 -0.1 -0.09 0.05


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.8 -5.8 -8.1 -9.9 -9.3 -6.4 -10.7 -5.9 -7.4 -8.0 -10.0 -10.7 -3.5 -3.4 -2.3
Bud 2.1 0.3 -0.2 -2.9 -1.4 -1.2 -2.6 -2.3 -1.4 1.8 1.3 -2.8 -2.4 -3.6 -1.0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 1.9 2.6 0 0 0 0 0 0 0 0 0
Cytoplasm -0.8 1.5 -0.2 -0.2 -3.1 -1.4 -0.5 -0.6 -0.2 -2.3 -3.5 -1.7 3.4 2.8 4.1
Endoplasmic Reticulum -3.6 -6.4 -3.6 -4.4 -7.4 -2.4 -3.1 -3.6 -3.2 -9.6 -12.2 -11.9 -8.3 -6.6 -5.3
Endosome 0.1 3.8 3.0 0.8 1.1 -3.0 -3.0 -3.5 -3.2 5.9 7.1 8.1 5.9 4.5 3.6
Golgi 0.4 -3.1 -11.2 -9.8 -11.6 -9.8 -12.2 -8.3 -9.0 -9.4 -11.2 -10.3 -1.5 0.7 -2.0
Mitochondria 6.1 3.2 9.6 9.9 12.2 13.3 14.4 12.1 11.4 -8.1 -9.3 -11.2 -6.1 -6.7 -4.2
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 3.0 0 0 0
Peroxisomes 0 0.9 0 0 0 0 0 0 0 16.0 16.7 16.3 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 11.8 12.0 12.5 5.4 4.8 0
Vacuole 0 2.1 2.7 3.4 4.6 2.0 2.0 0 0 0 0 0 4.2 7.5 5.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.8667 7.1582 6.6 6.8197 6.0473 6.776 8.0998 9.2861 8.9485 8.9812 8.0872 8.6251 8.497 9.2044 8.717 9.083 8.8873 8.9444
Actin 0.093 0.0379 0.17 0.1112 0.1659 0.1068 0.0697 0.0982 0.1073 0.1538 0.0911 0.0831 0.2438 0.1032 0.1279 0.1765 0.0702 0.1007
Bud 0.0029 0.0033 0.0022 0.0017 0.0026 0.0011 0.0008 0.0014 0.01 0.0007 0.0008 0.0006 0.0013 0.0009 0.0042 0.0047 0.0019 0.0009
Bud Neck 0.0019 0.0007 0.0038 0.0028 0.0015 0.0033 0.0014 0.0008 0.0014 0.0012 0.0008 0.0065 0.0018 0.0015 0.001 0.0031 0.0011 0.004
Bud Periphery 0.0035 0.0036 0.0032 0.0009 0.0016 0.001 0.0006 0.0006 0.0064 0.0005 0.0008 0.0004 0.0015 0.0003 0.0068 0.0055 0.0017 0.001
Bud Site 0.0265 0.0053 0.0124 0.0026 0.003 0.0014 0.0051 0.0112 0.009 0.001 0.001 0.0008 0.0025 0.0117 0.0038 0.0015 0.0044 0.0039
Cell Periphery 0.0045 0.0009 0.0033 0.0004 0.0004 0.0006 0.0002 0.0002 0.0003 0.0001 0.0002 0.0001 0.0002 0.0011 0.0007 0.0001 0.0003 0.0005
Cytoplasm 0.2148 0.138 0.0915 0.0854 0.0194 0.0529 0.036 0.0782 0.031 0.0657 0.0195 0.0377 0.0154 0.0772 0.0548 0.0054 0.0116 0.0646
Cytoplasmic Foci 0.1144 0.1487 0.155 0.1418 0.0326 0.1496 0.1825 0.1947 0.1602 0.1228 0.1648 0.171 0.1675 0.2453 0.1429 0.1839 0.1278 0.1129
Eisosomes 0.0011 0.0001 0.0005 0.0001 0.0003 0.0002 0.0003 0.0001 0.0001 0.0001 0.0003 0.0001 0.0013 0.0005 0.0002 0.0001 0.0001 0.0002
Endoplasmic Reticulum 0.028 0.01 0.0103 0.0171 0.0064 0.0196 0.0075 0.0059 0.0069 0.0013 0.006 0.0054 0.0058 0.0044 0.0143 0.0017 0.0042 0.0166
Endosome 0.147 0.3021 0.1747 0.3289 0.2917 0.2316 0.2191 0.2102 0.1828 0.2365 0.2264 0.1873 0.1727 0.1597 0.2284 0.1335 0.1934 0.2159
Golgi 0.3003 0.3074 0.2478 0.2656 0.4561 0.3697 0.3725 0.3682 0.4154 0.3562 0.4338 0.4597 0.2289 0.2451 0.2571 0.3119 0.4862 0.3632
Lipid Particles 0.0153 0.0053 0.0242 0.0114 0.0007 0.0143 0.0207 0.0029 0.0038 0.0022 0.0117 0.0093 0.0214 0.0241 0.0331 0.1049 0.0077 0.0165
Mitochondria 0.0118 0.012 0.0445 0.0086 0.0123 0.0231 0.0114 0.0048 0.0189 0.031 0.0097 0.014 0.0101 0.0153 0.0129 0.0106 0.0334 0.0305
None 0.0103 0.0006 0.001 0.0038 0.0002 0.001 0.0121 0.0003 0.0017 0.0002 0.0061 0.0006 0.0059 0.0006 0.0009 0.0002 0.0004 0.0006
Nuclear Periphery 0.0043 0.0021 0.0012 0.002 0.0004 0.0006 0.0037 0.0003 0.0003 0.0003 0.0049 0.0002 0.0487 0.0003 0.002 0.0005 0.001 0.0006
Nucleolus 0.0005 0.0001 0.0002 0.0001 0 0.0001 0.0003 0 0.0001 0 0.0001 0 0.0007 0.0197 0.0134 0.001 0.0001 0.0258
Nucleus 0.0018 0.0008 0.0005 0.0004 0.0001 0.0002 0.0007 0.0001 0.0003 0.0002 0.0006 0.0001 0.0082 0.0006 0.0009 0.0002 0.0003 0.0008
Peroxisomes 0.0036 0.0117 0.0436 0.0087 0.0005 0.0187 0.0488 0.0196 0.0403 0.0168 0.0167 0.0207 0.0322 0.0856 0.0574 0.05 0.0458 0.0363
Punctate Nuclear 0.0013 0.0004 0.0021 0.001 0.0001 0.0005 0.0036 0.0003 0.001 0.0002 0.0018 0.0008 0.0261 0.0012 0.0014 0.0012 0.0005 0.001
Vacuole 0.0107 0.0057 0.006 0.0033 0.0016 0.0019 0.0018 0.001 0.0014 0.0051 0.0011 0.0008 0.0017 0.0011 0.0291 0.0018 0.0043 0.0016
Vacuole Periphery 0.0026 0.0033 0.002 0.0022 0.0027 0.0018 0.0013 0.0008 0.0012 0.0041 0.0017 0.0009 0.0021 0.0007 0.0066 0.0018 0.0036 0.0017

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.6501 24.4211 20.3315 30.2302 34.9878 20.6441 26.9506 25.6081 23.87 29.5792
Translational Efficiency 1.2984 1.6812 1.5688 1.0729 1.03 1.6504 1.3923 1.2992 1.3971 1.2583

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1789 1700 398 1288 114 2145 145 1829 1903 3845 543 3117

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 859.81 1047.46 1263.41 1315.35 939.71 982.71 1235.14 1317.96 864.60 1011.34 1255.86 1316.88
Standard Deviation 109.15 140.34 139.36 217.11 108.83 145.44 161.30 188.35 110.77 146.78 146.08 200.74
Intensity Change Log 2 — 0.284805 0.555233 0.613357 — 0.064550 0.394387 0.488019 — 0.173988 0.473479 0.549265

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.031880 0.069218 0.027377 0.037146 0.035522 0.042180 0.021815 0.012385 0.032099 0.054134 0.025892 0.022617
Bud Neck 0.000607 0.001508 0.000916 0.004199 0.001096 0.001859 0.003106 0.002051 0.000636 0.001704 0.001501 0.002939
Bud Site 0.006142 0.017457 0.017717 0.075644 0.010040 0.020853 0.033871 0.037956 0.006376 0.019351 0.022031 0.053529
Cell Periphery 0.000507 0.000534 0.000616 0.000879 0.002340 0.000321 0.000307 0.000588 0.000616 0.000415 0.000534 0.000708
Cytoplasm 0.008613 0.008905 0.006759 0.070017 0.008562 0.009685 0.012008 0.053964 0.008610 0.009340 0.008160 0.060597
Cytoplasmic Foci 0.298441* 0.284780* 0.254696* 0.307233* 0.293285* 0.288494* 0.330405* 0.296972* 0.298132* 0.286852* 0.274913* 0.301212*
Eisosomes 0.000857 0.000570 0.000136 0.000083 0.000701 0.000385 0.000094 0.000064 0.000848 0.000467 0.000125 0.000072
Endoplasmic Reticulum 0.013776 0.008219 0.027953 0.002607 0.033855 0.004426 0.019461 0.004249 0.014979 0.006103 0.025685 0.003570
Endosome 0.102901 0.122346 0.178355 0.111025 0.185385 0.130216 0.201732* 0.149988 0.107842 0.126737 0.184598 0.133888
Golgi 0.475235* 0.436641* 0.376576* 0.230813* 0.321259* 0.437862* 0.245709* 0.280540* 0.466011* 0.437322* 0.341630* 0.259992*
Lipid Particles 0.034832 0.020180 0.026072 0.026415 0.040294 0.023868 0.020476 0.013391 0.035160 0.022237 0.024577 0.018773
Mitochondria 0.008757 0.005802 0.000210 0.002348 0.009052 0.008864 0.000176 0.002456 0.008775 0.007510 0.000201 0.002412
Mitotic Spindle 0.000807 0.002868 0.018450 0.046705 0.001285 0.004508 0.023230 0.053396 0.000836 0.003783 0.019726 0.050631
None 0.000093 0.000068 0.000020 0.000125 0.000084 0.000051 0.000012 0.000149 0.000092 0.000059 0.000018 0.000139
Nuclear Periphery 0.000013 0.000022 0.000318 0.000352 0.000124 0.000031 0.000204 0.000129 0.000020 0.000027 0.000288 0.000221
Nuclear Periphery Foci 0.000234 0.000530 0.009364 0.002730 0.003636 0.000670 0.005963 0.002022 0.000438 0.000608 0.008456 0.002314
Nucleolus 0.000005 0.000080 0.000005 0.000088 0.000609 0.000021 0.000022 0.000132 0.000041 0.000047 0.000009 0.000114
Nucleus 0.000067 0.000200 0.000050 0.000198 0.004533 0.000058 0.000078 0.000596 0.000334 0.000120 0.000058 0.000431
Peroxisomes 0.009040 0.012030 0.002831 0.040519 0.011258 0.013747 0.011508 0.016738 0.009173 0.012988 0.005148 0.026565
Vacuole 0.001747 0.003291 0.039503 0.030601 0.013944 0.004621 0.057049 0.052585 0.002477 0.004033 0.044188 0.043501
Vacuole Periphery 0.005445 0.004752 0.012076 0.010273 0.023135 0.007281 0.012772 0.019650 0.006505 0.006163 0.012262 0.015775

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.81 0.81 -1.20 6.22 -1.57 -0.70 1.19 2.49 9.50 1.37 -6.53 1.32 3.41 11.01 0.79
Bud Neck -1.88 -1.03 -9.08 -5.86 -10.69 -1.57 -2.90 -3.84 -0.78 1.45 -2.75 -2.67 -7.99 -4.36 -6.23
Bud Site -7.10 -4.61 -20.10 -15.88 -14.05 -4.46 -4.16 -11.12 -7.00 -0.78 -9.96 -6.52 -24.55 -16.16 -10.89
Cell Periphery -0.33 -0.75 -2.00 -1.79 -1.16 2.62 2.64 2.22 -1.49 -1.57 2.47 0.69 -0.60 -2.21 -1.07
Cytoplasm -0.36 1.02 -15.14 -15.02 -14.81 -0.56 -1.10 -13.43 -15.13 -11.36 -0.98 0.20 -21.41 -21.31 -19.71
Cytoplasmic Foci 2.21 4.67 -1.10 -2.94 -5.07 0.29 -1.63 -0.20 -1.34 2.02 2.17 2.69 -0.48 -2.97 -3.11
Eisosomes 3.17 9.06 9.94 10.50 3.09 2.02 3.96 4.19 9.06 1.52 4.83 9.66 10.51 13.83 3.78
Endoplasmic Reticulum 3.39 -2.74 7.65 6.02 5.09 2.88 1.23 2.90 0.26 2.57 5.79 -2.53 7.57 4.13 5.55
Endosome -5.26 -10.42 -1.45 3.15 9.20 4.32 -0.93 2.88 -4.16 4.14 -6.03 -11.82 -7.00 -1.66 8.14
Golgi 5.01 7.60 28.94 24.15 11.13 -5.94 2.89 2.34 20.21 -1.54 4.43 10.80 30.52 30.72 7.74
Lipid Particles 5.14 1.95 2.51 -2.49 -0.20 1.45 1.59 2.37 4.89 1.51 5.01 2.72 6.50 1.86 1.72
Mitochondria 2.34 9.39 6.59 3.71 -5.69 0.05 3.22 2.35 6.27 -3.76 1.19 9.84 6.74 7.18 -5.68
Mitotic Spindle -3.72 -5.05 -13.23 -12.59 -6.08 -3.17 -3.63 -14.65 -13.82 -4.54 -5.75 -6.25 -19.86 -18.57 -8.29
None 0.88 4.04 -0.63 -0.96 -1.77 0.65 1.43 -0.73 -1.24 -1.71 1.69 4.37 -0.95 -1.54 -2.29
Nuclear Periphery -2.82 -4.73 -3.35 -3.26 -0.29 1.43 -0.99 -0.28 -8.75 1.15 -1.55 -5.41 -4.92 -4.75 0.90
Nuclear Periphery Foci -2.12 -4.62 -5.80 -4.94 3.22 1.34 -0.68 0.73 -4.03 1.88 -0.69 -5.15 -7.27 -6.40 3.86
Nucleolus -1.18 0.49 -2.34 -0.17 -2.36 1.05 1.04 0.82 -1.76 -1.73 -0.18 0.95 -1.52 -1.43 -2.61
Nucleus -1.40 1.67 -5.04 -0.17 -5.46 1.02 1.01 0.86 -2.09 -2.03 0.75 1.04 -0.58 -2.03 -2.50
Peroxisomes -2.02 6.08 -9.76 -8.34 -11.78 -0.64 -0.02 -1.44 -1.51 -1.08 -3.43 2.77 -9.91 -7.44 -10.52
Vacuole -3.16 -8.96 -14.90 -13.95 1.70 1.86 -4.17 -7.08 -18.72 0.40 -3.10 -10.54 -23.67 -23.01 -0.05
Vacuole Periphery 0.98 -3.59 -4.07 -4.63 1.01 2.63 1.51 0.62 -8.35 -1.80 0.45 -3.37 -8.75 -9.65 -1.79
Standard name
Human Ortholog
Description Non-essential conserved protein with a role in mRNA decapping; specifically affects the function of the decapping enzyme Dcp1p; mediates decay of the RPS28B mRNA via binding to both Rps28Bp (or Rps28Ap) and the RPS28B mRNA; mediates decay of the YRA1 mRNA by a different, translation-independent mechanism; localizes to cytoplasmic mRNA processing bodies; forms cytoplasmic foci upon DNA replication stress
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Edc3

Edc3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Edc3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available