Standard name
Human Ortholog
Description Beta regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.05 0.08 0.08 0.08 0.09 0.05 0.08 0.08 0.06 0.06 0.05 0.06 0.1 0.19 0.06 0.07 0.1 0 0 0 0.18 0.17 0.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.12 0.05 0.07 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.84 0.62 0.76 0.78 0.78 0.73 0.68 0.63 0.63 0.62 0.59 0.58 0.83 0.78 0.62 0.81 0.61 0.63 0.75 0.77 0.66 0.5 0.36 0.32
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0.12 0.06 0 0.06 0.05 0.08 0.07 0.08 0.08 0 0 0.05 0 0.05 0.06 0.07 0.05 0.09 0.05 0.07 0.07
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.16 0.4 0.17 0.07 0.12 0.15 0.23 0.28 0.18 0.22 0.25 0.25 0.13 0.12 0.15 0.1 0.31 0.27 0.1 0.1 0.12 0.12 0.23 0.25
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 0 2 1 0 1 0 0 1 0 0 2 0 0 1 0 0 0 0 0 1
Bud 0 0 0 1 0 0 2 0 3 1 6 5 0 0 0 1 0 0 6 3 12 8 13 6
Bud Neck 0 0 0 0 1 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 2 0 1 0
Bud Site 0 0 0 0 1 1 3 3 4 5 7 4 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 2 0 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3 8 32 34 39 58 41 56 39 34 31 30 12 20 54 7 13 16 0 3 5 40 47 62
Endoplasmic Reticulum 0 0 1 0 0 0 0 1 1 0 0 0 0 0 0 4 5 3 0 0 4 2 3 3
Endosome 1 0 1 1 6 11 22 4 12 15 19 14 1 2 10 0 2 0 1 1 5 4 10 12
Golgi 3 0 7 2 1 6 3 2 0 0 0 0 0 0 0 0 1 0 0 1 2 2 1 3
Mitochondria 0 0 1 1 2 6 8 0 63 31 39 36 0 1 0 5 4 2 0 0 5 3 2 2
Nucleus 113 92 292 324 404 485 517 445 319 355 306 335 168 159 179 100 112 97 114 137 289 114 99 101
Nuclear Periphery 1 0 0 0 1 0 2 0 0 4 0 2 0 0 0 0 0 0 1 0 5 1 2 3
Nucleolus 2 2 2 48 30 24 46 37 43 41 42 46 4 7 14 3 10 9 10 9 38 12 19 21
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 1 2 5 0 2 3 0 0 0 0 0 1 0 1 0 4 5 5 7
Vac/Vac Membrane 21 59 66 29 61 97 174 194 91 126 130 146 26 24 44 12 57 42 14 18 53 27 61 78
Unique Cell Count 135 149 382 414 519 660 757 703 509 572 520 574 203 204 289 124 184 155 154 179 436 229 274 314
Labelled Cell Count 144 161 402 441 547 691 823 747 576 615 583 622 211 214 303 132 205 170 154 179 436 229 274 314


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 14.6 13.3 13.5 13.0 12.6 11.1 10.4 10.6 8.6 9.7 9.3 9.5 13.9 13.2 12.7 12.2 15.2 17.5 12.3 12.9 12.2
Std Deviation (1e-4) 2.6 2.6 3.1 4.0 4.1 3.3 2.5 2.4 2.6 2.6 2.6 2.4 3.5 3.5 3.7 2.9 4.3 4.8 3.7 4.6 3.8
Intensity Change (Log2) – – – -0.05 -0.1 -0.29 -0.37 -0.35 -0.65 -0.47 -0.55 -0.51 0.04 -0.03 -0.09 -0.15 0.17 0.37 -0.14 -0.06 -0.14

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.1 -0.5 0.2 -1.9 -0.2 -0.4 -1.5 -1.4 -1.9 -1.1 0.6 4.0 -1.0 -0.5 0.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 3.0 0 2.6 2.8 3.4 2.7 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 6.9 4.3 5.2 4.7 0 0 0 0 0 0
Nucleus 0.6 0.5 -1.1 -2.9 -4.4 -4.4 -4.7 -5.5 -5.8 1.8 0.4 -4.1 1.0 -3.8 -3.3
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 6.4 4.2 3.1 4.4 4.0 5.3 4.8 5.2 5.2 0 0 3.6 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -4.5 -2.4 -1.1 2.2 3.8 0.2 1.8 2.8 3.0 -1.4 -1.8 -0.7 -2.0 3.7 2.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.0539 7.3783 6.9533 6.3552 6.4246 6.4996 8.0849 9.2083 9.0736 9.4915 7.9367 8.8897 8.3051 8.9714 7.8826 7.3158 7.6848 7.795
Actin 0.0186 0 0.0116 0.0032 0.0002 0.0065 0.0247 0.0001 0.0032 0.0001 0.0001 0.0001 0.0108 0.0001 0.0009 0.0002 0.0001 0.0026
Bud 0.0009 0.0001 0.0006 0.0002 0.0001 0.0004 0.001 0.0001 0.0003 0.0002 0.0001 0.0002 0.0002 0.0001 0.0004 0.0001 0 0.0002
Bud Neck 0.0039 0.0007 0.0013 0.0011 0.0003 0.0338 0.0021 0.0022 0.0018 0.0032 0.0009 0.0145 0.001 0.0006 0.0025 0.0009 0.0008 0.0112
Bud Periphery 0.0022 0.0001 0.0014 0.0004 0 0.0007 0.0023 0.0002 0.0005 0.0004 0.0002 0.0004 0.0003 0.0001 0.0013 0.0001 0.0001 0.0004
Bud Site 0.005 0.0007 0.0032 0.0006 0.0001 0.0018 0.002 0.0015 0.0027 0.0009 0.0002 0.0006 0.0005 0.0014 0.0019 0.0006 0.0001 0.0004
Cell Periphery 0.0014 0.0001 0.0005 0.0001 0 0.0003 0.0005 0.0002 0.0005 0.0002 0 0.0003 0.0001 0.0001 0.0006 0 0 0.0002
Cytoplasm 0.0103 0.0011 0.0025 0.001 0.0031 0.0039 0.0095 0.0008 0.0119 0.0007 0.0017 0.0009 0.0054 0.0041 0.003 0.0012 0.0007 0.0009
Cytoplasmic Foci 0.0354 0 0.0039 0.0007 0 0.0038 0.0093 0 0.0115 0 0 0 0.0112 0.0035 0.001 0.0147 0 0.0027
Eisosomes 0.0003 0 0.0003 0.0004 0 0 0.0003 0 0.0001 0 0 0 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.0035 0.0001 0.0008 0.0003 0.0004 0.0036 0.0108 0.0001 0.0093 0.0001 0.0004 0.0001 0.0024 0.0004 0.0022 0.0002 0.0002 0.0018
Endosome 0.0136 0.0001 0.0043 0.0014 0.0008 0.0074 0.0561 0.0002 0.003 0.0001 0.0003 0.0002 0.0114 0.0033 0.0046 0.0088 0.0003 0.0107
Golgi 0.0058 0 0.0032 0.0008 0 0.0012 0.0129 0 0.0017 0 0 0 0.0038 0.0006 0.001 0.0014 0 0.0033
Lipid Particles 0.0098 0 0.0017 0.0123 0 0.0027 0.0106 0 0.0013 0 0 0 0.0124 0.0008 0.0025 0.0038 0 0.0045
Mitochondria 0.0126 0.0002 0.0098 0.0336 0.0007 0.0007 0.0091 0.0003 0.0008 0.0003 0.0004 0.0002 0.0033 0.0007 0.0088 0.0004 0.0006 0.0052
None 0.0103 0 0.0006 0.0013 0.0003 0.0007 0.0053 0.0001 0.0021 0 0 0.0002 0.0011 0.0009 0.0002 0.0005 0.0001 0.0001
Nuclear Periphery 0.0171 0.0027 0.0064 0.0068 0.0194 0.003 0.0495 0.0051 0.006 0.0033 0.0138 0.0036 0.0156 0.0072 0.0053 0.0051 0.0049 0.0023
Nucleolus 0.0184 0.0261 0.0353 0.0321 0.0067 0.0328 0.0403 0.0462 0.0746 0.0372 0.0078 0.0443 0.0081 0.0241 0.0396 0.017 0.0118 0.0342
Nucleus 0.7997 0.9659 0.8948 0.8962 0.9659 0.8907 0.7042 0.9399 0.8559 0.9512 0.9705 0.93 0.8992 0.9473 0.9067 0.932 0.9785 0.9149
Peroxisomes 0.0059 0 0.0099 0.0044 0 0.0008 0.0032 0 0.0057 0 0 0 0.0022 0.0004 0.0014 0.0051 0 0.0008
Punctate Nuclear 0.0122 0.0015 0.0027 0.0021 0.0005 0.0021 0.0328 0.0015 0.0017 0.0009 0.0009 0.0026 0.0091 0.0027 0.001 0.0074 0.001 0.0016
Vacuole 0.0102 0.0005 0.0044 0.0006 0.0006 0.0028 0.0085 0.0013 0.0051 0.001 0.0019 0.0017 0.0013 0.0015 0.0134 0.0004 0.0005 0.0014
Vacuole Periphery 0.0029 0.0001 0.001 0.0005 0.0008 0.0003 0.0049 0.0002 0.0004 0.0002 0.0006 0.0001 0.0006 0.0002 0.0017 0.0001 0.0002 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 84.3702 56.5664 64.711 62.3567 68.3686 80.3709 64.0456 65.1413 83.3289 66.0917
Translational Efficiency 1.2771 1.7813 1.4164 1.8469 1.395 1.2906 1.4974 1.3122 1.0321 1.2037

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1126 1216 1784 1431 1696 1929 1957 1969 2822 3145 3741 3400

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 977.90 1227.41 1435.91 1446.53 1066.92 1283.81 1332.68 1425.32 1031.40 1262.00 1381.91 1434.25
Standard Deviation 181.06 219.90 234.42 261.19 166.18 199.09 219.30 257.55 177.70 209.19 232.43 259.30
Intensity Change Log 2 — 0.327858 0.554206 0.564837 — 0.266980 0.320878 0.417834 — 0.296415 0.437178 0.490007

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000658 0.001019 0.001165 0.001807 0.000591 0.000693 0.001120 0.001144 0.000618 0.000819 0.001141 0.001423
Bud Neck 0.019015 0.058635 0.085621 0.174465 0.036115 0.042315 0.113427 0.135676 0.029292 0.048625 0.100167 0.152002
Bud Site 0.003833 0.006237 0.008742 0.014842 0.004228 0.005449 0.008915 0.014428 0.004070 0.005754 0.008832 0.014602
Cell Periphery 0.000399 0.000389 0.000229 0.000271 0.000211 0.000286 0.000222 0.000224 0.000286 0.000326 0.000225 0.000244
Cytoplasm 0.022318 0.014723 0.005664 0.005783 0.009382 0.005305 0.004388 0.012283 0.014543 0.008946 0.004997 0.009547
Cytoplasmic Foci 0.000890 0.000448 0.000181 0.003403 0.000366 0.000514 0.000079 0.000524 0.000575 0.000488 0.000128 0.001736
Eisosomes 0.000037 0.000049 0.000062 0.000077 0.000031 0.000049 0.000058 0.000063 0.000033 0.000049 0.000060 0.000069
Endoplasmic Reticulum 0.007279 0.008662 0.004596 0.005098 0.007911 0.007797 0.004506 0.003474 0.007659 0.008131 0.004549 0.004158
Endosome 0.000503 0.000696 0.000316 0.003272 0.000534 0.001268 0.000263 0.000981 0.000522 0.001047 0.000288 0.001945
Golgi 0.000123 0.000170 0.000101 0.005890 0.000145 0.000536 0.000069 0.001558 0.000136 0.000394 0.000085 0.003381
Lipid Particles 0.000164 0.000247 0.000120 0.000478 0.000150 0.000335 0.000084 0.000272 0.000156 0.000301 0.000101 0.000359
Mitochondria 0.000668 0.002964 0.002877 0.006854 0.001994 0.001451 0.002509 0.003487 0.001465 0.002036 0.002685 0.004904
Mitotic Spindle 0.000294 0.003791 0.003806 0.009344 0.001003 0.004746 0.001636 0.025183 0.000720 0.004377 0.002670 0.018516
None 0.012563 0.003339 0.002823 0.003825 0.002088 0.002487 0.002128 0.007244 0.006267 0.002817 0.002460 0.005805
Nuclear Periphery 0.000384 0.001038 0.000892 0.002064 0.000812 0.001120 0.000735 0.001789 0.000641 0.001088 0.000810 0.001904
Nuclear Periphery Foci 0.000899 0.001232 0.000233 0.001721 0.000422 0.000621 0.000108 0.001013 0.000612 0.000857 0.000167 0.001311
Nucleolus 0.017332 0.009427 0.008447 0.040174 0.011593 0.015764 0.010038 0.035736 0.013883 0.013314 0.009279 0.037604
Nucleus 0.910506 0.882742 0.870859 0.711657 0.920120 0.905660 0.847550 0.750579 0.916284 0.896798 0.858665 0.734197
Peroxisomes 0.000307 0.000328 0.000270 0.001076 0.000277 0.000410 0.000236 0.000492 0.000289 0.000378 0.000253 0.000738
Vacuole 0.001666 0.003231 0.002619 0.005861 0.001775 0.002766 0.001764 0.003134 0.001732 0.002946 0.002171 0.004282
Vacuole Periphery 0.000163 0.000636 0.000378 0.002039 0.000253 0.000428 0.000165 0.000715 0.000217 0.000508 0.000267 0.001272

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.97 -13.07 -14.99 -8.34 -3.11 -2.28 -12.31 -13.62 -11.27 -0.64 -5.04 -18.01 -20.17 -13.89 -2.40
Bud Neck -10.44 -20.18 -29.64 -19.17 -13.11 -1.98 -19.09 -22.51 -21.37 -2.88 -8.29 -26.71 -36.01 -28.86 -10.81
Bud Site -3.40 -7.73 -10.72 -7.98 -3.16 -1.48 -6.44 -8.91 -8.14 -3.80 -3.12 -9.86 -13.40 -11.33 -4.81
Cell Periphery 0.19 2.27 2.18 2.45 -0.31 -1.32 -0.05 1.06 1.94 1.10 -0.68 1.87 2.39 2.98 0.91
Cytoplasm 2.50 6.58 6.33 4.45 -0.26 2.76 4.16 -0.61 -3.94 -5.78 3.67 7.69 4.51 0.79 -4.94
Cytoplasmic Foci 1.31 2.09 -1.11 -2.37 -2.98 -0.54 2.65 0.87 1.22 -2.44 0.73 2.91 -0.90 -1.61 -3.36
Eisosomes -3.19 -8.82 -10.08 -5.46 -0.91 -5.36 -9.81 -10.04 -2.32 0.39 -6.19 -13.39 -14.27 -5.23 -0.11
Endoplasmic Reticulum -2.63 5.05 5.53 8.05 0.50 0.05 8.86 12.88 12.20 5.57 -1.54 9.93 13.37 14.32 4.40
Endosome -1.87 1.88 -3.18 -2.53 -3.56 -2.21 4.86 -0.84 1.80 -3.11 -2.56 4.73 -3.22 -0.06 -4.48
Golgi -1.09 -1.57 -2.35 -2.30 -2.31 -1.63 1.02 -1.34 -0.35 -1.45 -1.74 0.24 -2.70 -2.05 -2.72
Lipid Particles -1.14 -0.49 -2.21 -0.90 -2.10 -1.56 1.60 -1.64 0.84 -2.58 -1.87 0.36 -2.77 0.33 -3.15
Mitochondria -2.63 -23.37 -10.65 -3.23 -4.22 0.84 -1.91 -3.73 -9.70 -5.94 -1.17 -5.79 -8.60 -6.88 -6.13
Mitotic Spindle -2.73 -5.26 -5.60 -3.20 -1.64 -3.09 -1.76 -8.54 -6.22 -7.64 -4.07 -5.16 -10.16 -6.92 -7.07
None 4.79 5.08 4.77 -0.25 -0.84 -1.17 -0.14 -6.06 -5.04 -6.02 4.31 4.84 1.65 -4.28 -5.53
Nuclear Periphery -3.61 -11.47 -8.87 -3.72 -4.38 -1.11 -0.70 -4.45 -1.79 -4.31 -2.50 -7.13 -8.58 -3.35 -5.90
Nuclear Periphery Foci -0.78 2.64 -0.76 0.11 -2.00 -1.28 2.22 -1.24 -0.49 -2.24 -1.19 3.35 -1.38 -0.21 -2.91
Nucleolus 3.61 1.48 -10.75 -13.08 -11.95 -3.18 -1.86 -13.81 -11.56 -12.60 -0.18 -0.43 -17.55 -17.12 -17.33
Nucleus 4.59 10.37 24.70 19.90 16.30 3.04 15.30 26.39 23.48 11.74 5.28 18.45 36.16 30.94 19.57
Peroxisomes -0.38 -1.84 -4.20 -3.93 -2.86 -1.51 -0.24 -3.01 -1.21 -4.33 -1.54 -1.47 -5.12 -3.75 -4.24
Vacuole -3.66 -4.12 -7.57 -2.46 -2.01 -1.88 -1.92 -6.16 -2.97 -5.54 -3.72 -4.49 -9.61 -3.95 -4.31
Vacuole Periphery -2.23 -1.21 -4.00 -1.61 -3.09 -2.30 1.48 -2.57 -0.49 -3.76 -3.12 -0.42 -4.70 -1.75 -4.12
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Beta regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases
Localization
Cell Percentages nucleus (95%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-5

Ckb1

Ckb1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ckb1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available