Standard name
Human Ortholog
Description Ammonium permease; belongs to Mep-Amt-Rh family of well-conserved ammonium (NH4+) transporters that includes the human Rh factors; expression is under the nitrogen catabolite repression regulation; activity regulated by TORC1 effectors, Npr1p and Par32p; human homolog RHCG complements yeast null mutant; mutations in human homolog RHCG implicated in metabolic acidosis; MEP1 has a paralog, MEP3, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.27 0.26 0.19 0.38 0.33 0.44 0.31 0.2 0.15 0.15 0.12 0.08 0.3 0.25 0.27 0.16 0.07 0.07 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0.07 0.08 0.06 0.07 0.09 0.08 0 0 0 0 0.06 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.89 0.92 0.91 0.94 0.81 0.74 0.63 0.4 0.5 0.4 0.39 0.37 0.94 0.89 0.84 0.65 0.68 0.81 0.92 0.91 0.92 0.89 0.88 0.88
Cytoplasm 0 0.05 0.05 0 0.08 0.18 0.24 0.3 0.4 0.46 0.56 0.61 0.05 0.1 0.14 0.34 0.33 0.15 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0.14 0.13 0.2 0.25 0.22 0.19 0.14 0.14 0 0 0 0.08 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.09 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.06 0 0.05 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 51 104 68 101 74 170 166 84 58 60 49 37 42 29 32 14 5 5 4 12 8 4 9 8
Bud 2 6 4 5 6 17 35 34 25 26 38 37 3 1 1 3 4 0 1 6 3 2 5 5
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 3
Bud Site 0 1 0 0 0 0 0 1 2 1 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 170 368 325 250 180 284 335 167 199 158 160 164 130 102 100 57 49 59 245 455 383 138 238 267
Cytoplasm 7 18 18 11 17 69 128 126 158 182 228 274 7 12 17 30 24 11 1 5 2 0 2 2
Endoplasmic Reticulum 3 7 10 3 30 51 107 105 88 77 58 61 2 2 2 7 0 0 2 6 5 3 3 6
Endosome 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 1 0 3 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 0
Mitochondria 17 5 7 4 0 5 1 4 0 1 2 2 0 0 0 3 3 8 6 6 8 1 2 4
Nucleus 0 0 0 0 2 0 2 2 2 6 4 5 0 0 0 1 0 1 0 0 0 0 0 0
Nuclear Periphery 1 0 1 0 0 1 2 5 1 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0
Nucleolus 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 2 1 2 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 4 3 1 0 1 0 1 0 2 1 1 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 1 0 0 0 1 4 25 7 18 18 31 1 0 0 0 0 0 1 1 0 0 1 2
Unique Cell Count 190 398 359 267 221 383 534 416 395 395 410 447 139 115 119 88 72 73 266 499 418 155 270 305
Labelled Cell Count 252 510 436 374 309 605 784 557 541 531 558 617 185 148 153 116 85 85 266 499 418 155 270 305


Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 28.5 28.6 25.4 26.0 23.6 20.6 20.3 18.9 19.1 18.5 18.4 18.2 22.9 19.9 18.8 19.1 24.1 29.7 22.7 24.1 27.3
Std Deviation (1e-4) 6.5 6.7 6.7 6.5 6.9 7.2 6.5 6.7 5.9 6.0 5.7 5.4 5.9 6.0 5.8 6.0 7.9 9.3 7.3 7.2 7.6
Intensity Change (Log2) – – – 0.03 -0.1 -0.3 -0.32 -0.42 -0.41 -0.46 -0.47 -0.48 -0.15 -0.35 -0.43 -0.41 -0.08 0.23 -0.16 -0.07 0.1


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 5.3 4.0 7.4 4.0 0.4 -1.6 -1.4 -2.7 -4.5 2.7 1.5 1.8 -0.7 -2.5 -2.5
Bud 0 0 2.7 3.9 4.5 3.7 3.8 5.0 4.6 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 1.4 -3.2 -5.8 -9.3 -14.5 -12.0 -14.4 -14.8 -15.6 1.1 -0.6 -2.0 -6.1 -5.1 -2.4
Cytoplasm -0.5 1.3 5.5 7.5 9.0 11.3 12.8 15.0 16.5 0 2.1 3.4 7.9 7.4 0
Endoplasmic Reticulum -1.4 5.0 5.2 7.5 8.8 7.9 7.2 5.5 5.4 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 -0.7 0 -1.2 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 4.7 0 4.1 4.0 5.1 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.5208 7.0007 5.6957 6.3225 5.8545 7.0587 6.7608 10.7437 8.1218 7.9164 8.4091 9.7054 7.176 11.2967 9.111 7.6007 8.791 9.4971
Actin 0.0509 0.0141 0.0154 0.0132 0.0161 0.008 0.0218 0.0026 0.0157 0.0174 0.0163 0.0077 0.0129 0.0111 0.008 0.0059 0.0024 0.0087
Bud 0.0044 0.0073 0.0088 0.0337 0.008 0.0022 0.0016 0.0033 0.0027 0.0062 0.0019 0.0008 0.002 0.0024 0.0023 0.0038 0.0007 0.0012
Bud Neck 0.0093 0.0036 0.0072 0.0366 0.0039 0.0043 0.0046 0.0022 0.0059 0.0059 0.0068 0.0102 0.0018 0.0042 0.0066 0.0081 0.0029 0.013
Bud Periphery 0.0448 0.0305 0.055 0.0341 0.076 0.0349 0.0179 0.0286 0.0351 0.0746 0.0127 0.0209 0.025 0.0155 0.0216 0.0339 0.0152 0.0231
Bud Site 0.0333 0.12 0.0599 0.0179 0.0345 0.003 0.0294 0.0756 0.0334 0.0244 0.0325 0.0018 0.0202 0.0989 0.0424 0.0118 0.0227 0.003
Cell Periphery 0.4806 0.4887 0.5428 0.6021 0.4944 0.6735 0.7217 0.7462 0.7294 0.7725 0.7554 0.8313 0.7742 0.7075 0.7812 0.8136 0.844 0.8303
Cytoplasm 0.2067 0.2601 0.1821 0.0883 0.1691 0.166 0.0831 0.1049 0.126 0.0475 0.092 0.083 0.0838 0.1058 0.0875 0.0649 0.0767 0.0732
Cytoplasmic Foci 0.0106 0.0043 0.0124 0.0017 0.0086 0.0032 0.002 0.0006 0.0007 0.0006 0.0043 0.0008 0.0011 0.001 0.0009 0.005 0.0002 0.0005
Eisosomes 0.0228 0.0087 0.0091 0.0093 0.0019 0.0069 0.0361 0.0048 0.0166 0.0174 0.0187 0.0112 0.0226 0.0169 0.0126 0.0077 0.0065 0.0068
Endoplasmic Reticulum 0.0249 0.0105 0.0117 0.0682 0.0056 0.0164 0.0172 0.0097 0.0067 0.019 0.0124 0.0152 0.0114 0.0154 0.0107 0.0149 0.0183 0.015
Endosome 0.0233 0.0028 0.017 0.0023 0.0271 0.003 0.0018 0.0001 0.0002 0.0004 0.0118 0.0012 0.0004 0.0004 0.0001 0.0005 0 0.0002
Golgi 0.0122 0.0014 0.0082 0.0018 0.018 0.0017 0.0018 0.0001 0.0009 0.0018 0.0073 0.0008 0.0014 0.0009 0.0007 0.0004 0.0004 0.0008
Lipid Particles 0.0136 0.002 0.0073 0.0057 0.0056 0.0076 0.0035 0.0006 0.0009 0.0022 0.0018 0.0017 0.0017 0.0013 0.0012 0.0009 0.0013 0.0026
Mitochondria 0.0136 0.0013 0.0109 0.0505 0.0191 0.0068 0.0028 0.0005 0.0007 0.0007 0.002 0.0042 0.0015 0.0005 0.0002 0.0008 0.0001 0.0025
None 0.0171 0.0358 0.033 0.0185 0.0576 0.0397 0.0431 0.014 0.0217 0.0016 0.017 0.0027 0.0314 0.0122 0.0197 0.0195 0.0007 0.0125
Nuclear Periphery 0.0067 0.0009 0.0011 0.0018 0.0006 0.0016 0.0019 0.0009 0.0006 0.001 0.0005 0.0012 0.0011 0.0012 0.0005 0.0008 0.0006 0.0005
Nucleolus 0.0009 0.0003 0.0004 0.0013 0.0003 0.0002 0.0004 0.0002 0.0001 0.0002 0.0003 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001
Nucleus 0.0037 0.0007 0.0011 0.002 0.0008 0.0058 0.0007 0.0003 0.0002 0.0004 0.0005 0.0002 0.0003 0.0003 0.0002 0.0003 0.0002 0.0001
Peroxisomes 0.0017 0.0003 0.0065 0.001 0.0018 0.0025 0.0012 0 0.0001 0.0001 0.0003 0.0001 0.0003 0.0001 0.0001 0.0017 0 0.0014
Punctate Nuclear 0.0023 0.0002 0.0009 0.0004 0.0001 0.0008 0.0004 0.0001 0.0001 0.0001 0.0001 0.0003 0.0001 0.0001 0.0001 0.0002 0 0
Vacuole 0.0148 0.0063 0.0085 0.0085 0.0484 0.0113 0.0068 0.0046 0.0022 0.006 0.0051 0.0045 0.0066 0.0041 0.0033 0.005 0.0069 0.0042
Vacuole Periphery 0.0015 0.0002 0.0009 0.0008 0.0026 0.0003 0.0003 0.0001 0 0.0002 0.0003 0.0001 0.0002 0.0001 0 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8.2065 4.0015 8.9079 8.1771 6.771 6.7107 10.9578 6.8268 9.2652 8.6863
Translational Efficiency 0.9731 1.0696 0.4253 0.6026 0.674 0.8996 0.4354 0.5778 0.6701 0.4936

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
111 366 335 1319 2349 1891 2368 1682 2460 2257 2703 3001

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1246.37 1867.64 1439.43 865.89 1925.47 1754.03 1616.60 844.35 1894.83 1772.45 1594.64 853.82
Standard Deviation 244.96 433.49 224.55 125.83 415.92 389.89 310.83 120.58 433.31 399.48 307.08 123.38
Intensity Change Log 2 — 0.583484 0.207765 -0.525477 — -0.134537 -0.252248 -1.189298 — 0.191335 -0.053661 -0.891121

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.013369 0.002710 0.041324 0.031179 0.000233 0.001744 0.006265 0.027360 0.000826 0.001901 0.010610 0.029039
Bud Neck 0.023834 0.002637 0.016707 0.027943 0.000478 0.001269 0.005010 0.027754 0.001532 0.001491 0.006460 0.027837
Bud Site 0.044634 0.030657 0.176814* 0.080270 0.002269 0.022945 0.037744 0.079615 0.004180 0.024195 0.054980 0.079903
Cell Periphery 0.574592* 0.931156* 0.616028* 0.035043 0.982616* 0.951600* 0.914205* 0.034186 0.964205* 0.948285* 0.877250* 0.034563
Cytoplasm 0.068602 0.007699 0.061414 0.389064* 0.000723 0.006720 0.016705 0.434047* 0.003786 0.006879 0.022246 0.414276*
Cytoplasmic Foci 0.008021 0.003548 0.007410 0.032005 0.000085 0.000875 0.000331 0.036855 0.000443 0.001309 0.001209 0.034723
Eisosomes 0.005410 0.004940 0.009116 0.020624 0.001157 0.001946 0.004516 0.016701 0.001349 0.002431 0.005086 0.018425
Endoplasmic Reticulum 0.007197 0.002825 0.021737 0.007232 0.001639 0.004344 0.004781 0.005018 0.001890 0.004098 0.006883 0.005991
Endosome 0.008304 0.001468 0.004136 0.001961 0.000313 0.000643 0.000691 0.003579 0.000673 0.000777 0.001118 0.002868
Golgi 0.007897 0.002376 0.005042 0.001044 0.000329 0.000616 0.000467 0.001663 0.000670 0.000902 0.001034 0.001391
Lipid Particles 0.002522 0.001034 0.014124 0.003493 0.000126 0.000422 0.000986 0.003556 0.000234 0.000521 0.002614 0.003528
Mitochondria 0.018777 0.000236 0.000251 0.000569 0.000224 0.000957 0.000546 0.001419 0.001061 0.000840 0.000509 0.001045
Mitotic Spindle 0.002520 0.000548 0.000773 0.004291 0.000425 0.000547 0.000488 0.003365 0.000519 0.000547 0.000523 0.003772
None 0.000034 0.000019 0.000045 0.003650 0.000015 0.000228 0.000058 0.001912 0.000016 0.000194 0.000056 0.002676
Nuclear Periphery 0.000226 0.000292 0.000290 0.000268 0.001105 0.000755 0.000675 0.000286 0.001065 0.000680 0.000627 0.000278
Nuclear Periphery Foci 0.001257 0.000158 0.001845 0.001695 0.000101 0.000115 0.000173 0.001105 0.000153 0.000122 0.000380 0.001364
Nucleolus 0.000018 0.000024 0.000017 0.000208 0.000039 0.000027 0.000031 0.000356 0.000038 0.000027 0.000029 0.000291
Nucleus 0.006394 0.000288 0.001648 0.154031* 0.000086 0.000322 0.000802 0.150513* 0.000371 0.000317 0.000907 0.152059*
Peroxisomes 0.000510 0.000104 0.000910 0.001517 0.000074 0.000179 0.000386 0.001690 0.000093 0.000167 0.000451 0.001614
Vacuole 0.196084 0.006581 0.020068 0.203786* 0.006584 0.003024 0.004679 0.167841 0.015135 0.003601 0.006586 0.183639
Vacuole Periphery 0.009796 0.000699 0.000301 0.000125 0.001380 0.000721 0.000462 0.001180 0.001759 0.000718 0.000442 0.000716

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.67 -4.68 -2.44 -8.95 3.36 -4.96 -9.89 -11.83 -10.96 -8.33 -3.22 -11.73 -15.29 -14.46 -7.67
Bud Neck 2.71 0.84 0.10 -11.89 -2.59 -5.09 -12.65 -15.59 -15.07 -12.37 0.05 -9.66 -18.73 -19.61 -14.54
Bud Site 1.19 -7.36 -1.33 -4.65 8.52 -7.92 -13.86 -17.37 -10.36 -7.08 -8.00 -17.29 -21.43 -11.97 -3.19
Cell Periphery -8.93 -1.33 12.86 90.12* 31.40* 7.88 16.85 339.04* 212.82* 196.03* 3.29 16.20 274.55 240.20* 176.55*
Cytoplasm 5.79 0.69 -22.72 -45.94 -30.69 -5.93 -11.12 -64.69* -63.09* -60.75* -2.76 -11.39 -79.47* -78.12* -72.80*
Cytoplasmic Foci 1.48 0.26 -7.32 -12.18 -11.33 -2.32 -6.00 -23.18 -22.17 -23.02 -2.02 -3.31 -30.61 -28.22 -29.67
Eisosomes 0.17 -2.36 -4.76 -5.39 -3.43 -3.67 -9.89 -11.48 -10.71 -8.25 -4.06 -11.46 -14.19 -12.76 -9.79
Endoplasmic Reticulum 1.95 -4.58 0.26 -3.31 5.93 -3.72 -5.43 -6.67 -0.66 -0.09 -3.40 -8.06 -7.74 -2.22 1.96
Endosome 2.11 1.23 2.01 -0.66 3.20 -3.78 -4.70 -7.67 -6.77 -6.68 -0.60 -2.51 -6.98 -7.07 -5.81
Golgi 1.47 0.76 2.03 1.24 6.33 -3.79 -1.53 -2.26 -1.65 -1.95 -0.93 -1.98 -1.37 -0.62 -0.31
Lipid Particles 1.53 -3.63 -1.08 -2.52 3.46 -2.38 -5.71 -15.24 -12.34 -9.56 -1.68 -5.66 -18.14 -12.07 -1.67
Mitochondria 1.77 1.77 1.74 -1.72 -1.65 -2.70 -5.64 -3.27 -0.72 -2.24 0.37 1.13 0.23 -0.25 -2.15
Mitotic Spindle 1.46 1.29 -0.95 -2.78 -2.61 -1.95 -2.21 -3.72 -3.54 -3.64 -0.42 -0.11 -4.38 -4.34 -4.38
None 1.27 -0.88 -4.22 -4.25 -4.21 -1.62 -2.67 -3.44 -2.91 -3.36 -1.62 -2.87 -5.46 -4.87 -5.37
Nuclear Periphery -0.92 -0.97 -3.43 -3.07 -3.70 4.31 5.66 10.19 8.79 8.98 5.09 6.08 9.69 7.49 7.70
Nuclear Periphery Foci 5.49 -1.47 -2.20 -12.85 0.08 -0.49 -2.63 -12.65 -12.98 -12.27 1.32 -4.56 -17.12 -18.50 -13.02
Nucleolus -0.54 0.21 -3.46 -3.41 -3.50 5.47 4.09 -1.55 -1.62 -1.60 5.54 4.37 -2.27 -2.39 -2.37
Nucleus 1.66 1.34 -23.05 -31.38 -31.08 -2.59 -6.39 -35.18 -35.12 -34.99* 0.52 -2.37 -46.98 -47.08 -46.87
Peroxisomes 3.16 -1.81 -3.41 -5.89 -1.44 -3.18 -3.15 -7.05 -6.59 -5.18 -2.35 -3.94 -9.10 -8.68 -5.92
Vacuole 6.94 6.43 -1.65 -34.35 -30.32 4.79 2.42 -35.38 -36.33 -35.99 6.98 5.11 -44.47 -50.38 -49.52
Vacuole Periphery 2.01 2.10 2.15 5.82 4.34 2.38 3.35 0.86 -0.80 -1.54 3.11 3.97 2.97 0.53 -0.84
Standard name
Human Ortholog
Description Ammonium permease; belongs to Mep-Amt-Rh family of well-conserved ammonium (NH4+) transporters that includes the human Rh factors; expression is under the nitrogen catabolite repression regulation; activity regulated by TORC1 effectors, Npr1p and Par32p; human homolog RHCG complements yeast null mutant; mutations in human homolog RHCG implicated in metabolic acidosis; MEP1 has a paralog, MEP3, that arose from the whole genome duplication
Localization
Cell Percentages cell periphery (96%)
Cell Cycle Regulation No
Subcompartmental Group cell periphery-1

Mep1

Mep1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mep1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available