Standard name
Human Ortholog
Description Cyclic nucleotide phosphodiesterase; hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.05 0.06 0.05 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.06 0.07 0 0.06 0.07 0.12
Bud 0 0.05 0 0.06 0 0.07 0.05 – 0.06 0.05 0.06 0 0.05 0.07 0 0 0 0.07 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.05 0.06 0.05 0.05 0.05 0 – 0 0 0 0 0.05 0.05 0.06 0.06 0.09 0.12 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.05 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.22 0.09 0.31 0.19 0.26 0 0.16 – 0 0.09 0.06 0 0.27 0.27 0.31 0.13 0.12 0.19 0.23 0.23 0.24 0.16 0.2 0.18
Golgi 0.1 0.09 0.16 0.1 0.13 0 0.05 – 0 0 0 0 0.22 0.12 0.16 0.58 0.5 0.38 0.38 0.35 0.32 0.46 0.42 0.39
Mitochondria 0.74 0.76 0.33 0.66 0.45 0.88 0.68 – 0.85 0.83 0.83 0.79 0.36 0.48 0.38 0.09 0.13 0.08 0.1 0.2 0.14 0.11 0.09 0.08
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0.05 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.13 0.06 0.08 0.06 0.1 0 0.1 – 0.1 0.11 0.08 0.12 0.27 0.17 0.33 0.05 0.06 0.15 0.2 0.1 0.24 0.17 0.18 0.18
SpindlePole 0.07 0 0.2 0.08 0.15 0.06 0.12 – 0.07 0.13 0.07 0.06 0.06 0.07 0.07 0.08 0.07 0.05 0 0 0 0 0 0
Vac/Vac Membrane 0 0.06 0 0 0 0 0 – 0 0 0 0 0 0 0 0.12 0.16 0.07 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 9 27 9 7 7 4 3 – 4 2 3 3 8 7 2 4 1 6 26 49 7 14 29 41
Bud 12 27 5 10 9 12 13 – 17 15 16 8 13 23 3 5 9 11 1 1 0 0 1 2
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0
Bud Site 0 1 0 1 0 4 0 – 8 7 5 2 0 0 0 0 0 1 – – – – – –
Cell Periphery 1 3 3 0 1 0 3 – 0 2 0 2 3 2 0 1 0 3 0 0 0 0 0 0
Cytoplasm 7 31 9 7 11 9 5 – 7 3 6 3 13 16 19 16 20 19 2 2 0 0 2 0
Endoplasmic Reticulum 3 29 4 0 4 3 2 – 1 1 1 1 5 2 1 5 7 2 1 2 0 0 3 2
Endosome 89 51 45 29 56 2 40 – 11 27 15 11 68 92 92 33 27 31 106 154 56 36 84 60
Golgi 39 49 23 15 29 0 12 – 1 5 1 4 55 41 47 143 117 60 181 236 76 106 178 133
Mitochondria 304 437 47 102 97 153 173 – 247 246 205 208 91 162 112 23 31 13 44 134 32 24 36 26
Nucleus 1 1 0 1 2 2 1 – 1 0 1 0 0 2 0 0 2 0 0 0 0 0 0 0
Nuclear Periphery 2 3 1 0 4 1 4 – 5 6 4 4 4 1 5 6 4 2 0 1 0 0 3 0
Nucleolus 5 3 0 2 3 5 9 – 14 10 12 12 1 7 8 9 6 5 0 1 0 0 0 0
Peroxisomes 55 32 12 10 22 2 25 – 29 34 20 31 69 56 97 13 14 24 95 71 56 38 76 63
SpindlePole 28 21 29 12 32 11 30 – 20 38 18 16 16 25 21 20 16 8 7 6 2 4 6 3
Vac/Vac Membrane 14 34 2 0 7 7 5 – 2 2 4 2 10 15 9 31 38 11 1 13 1 3 3 1
Unique Cell Count 409 576 144 154 215 174 256 291 296 247 262 255 337 295 248 234 160 472 681 237 230 430 342
Labelled Cell Count 569 749 189 196 284 215 325 367 398 311 307 356 452 416 309 292 196 472 681 237 230 430 342


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 6.1 6.5 6.4 6.9 4.9 6.2 – 5.7 6.0 5.7 6.0 7.8 7.3 8.4 10.8 11.8 10.5 6.1 6.4 6.8
Std Deviation (1e-4) 1.1 0.9 0.9 1.6 1.6 1.3 1.1 – 1.4 1.2 1.3 1.1 6.2 1.8 2.3 2.2 2.7 2.2 1.0 2.0 2.3
Intensity Change (Log2) – – – -0.02 0.09 -0.41 -0.07 – -0.18 -0.1 -0.18 -0.1 0.27 0.17 0.38 0.74 0.86 0.7 -0.09 -0.01 0.07


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.7 -1.3 0 0 – 0 0 0 0 -1.5 0 0 0 0 -1.0
Bud 1.2 0.3 0 0.7 – 1.1 0.8 1.3 0 0.8 1.4 0 0 0.2 1.3
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.7 -0.5 -0.4 -2.2 – -2.0 0 -1.9 0 -0.5 -0.7 0.1 0.1 0.8 1.7
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome -2.5 -1.1 0 -3.7 – -8.1 -5.9 -6.7 -7.6 -1.0 -0.9 0 -4.3 -4.7 -2.4
Golgi -1.6 -0.7 0 -3.8 – -6.7 -5.8 -6.2 -5.6 1.4 -1.1 0 8.1 6.7 4.2
Mitochondria 5.8 2.4 0 6.7 – 11.0 10.5 10.0 9.3 0.6 3.1 1.1 -5.8 -4.5 -5.4
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes -0.6 0.6 0 0.5 – 0.5 1.0 -0.1 1.1 4.5 2.4 5.6 -1.2 -0.9 1.8
SpindlePole -3.1 -1.3 0 -2.3 – -4.1 -2.0 -3.8 -4.3 -4.2 -4.0 -4.0 -3.5 -3.9 -4.0
Vacuole 0 0 0 0 – 0 0 0 0 0 1.7 0 3.8 4.6 2.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.9301 5.1164 5.0268 5.1515 4.8722 5.2077 3.8987 4.1534 4.0039 3.7908 3.6504 4.1207 4.4537 5.2259 4.773 4.9525 4.3324 4.9444
Actin 0.0419 0.0302 0.0577 0.0691 0.0235 0.0382 0.0481 0.0242 0.0821 0.05 0.0042 0.0379 0.0308 0.0426 0.0872 0.093 0.0515 0.0668
Bud 0.0004 0.0005 0.003 0.0006 0.0007 0.0002 0.0003 0.0003 0.0007 0.0001 0.0005 0.0002 0.0003 0.0014 0.001 0.001 0.0005 0.0002
Bud Neck 0.0021 0.0005 0.0007 0.004 0.0007 0.0006 0.0072 0.0005 0.0018 0.0003 0.0004 0.0006 0.0007 0.0006 0.0007 0.0008 0.0006 0.0009
Bud Periphery 0.0004 0.0005 0.0049 0.0006 0.0017 0.0002 0.0003 0.0002 0.0007 0.0002 0.0009 0.0002 0.0003 0.0011 0.0009 0.0009 0.0008 0.0002
Bud Site 0.0028 0.0012 0.003 0.0148 0.001 0.0003 0.0013 0.0014 0.0042 0.0003 0.0007 0.0003 0.0014 0.0148 0.0019 0.0014 0.0005 0.0004
Cell Periphery 0.0002 0.0001 0.0001 0.0002 0.0003 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001
Cytoplasm 0.0057 0.002 0.0022 0.0014 0.012 0.0007 0.0041 0.0023 0.0116 0.0021 0.0014 0.0013 0.0017 0.0139 0.0017 0.003 0.0026 0.001
Cytoplasmic Foci 0.1107 0.1506 0.1015 0.1035 0.1151 0.0904 0.1592 0.189 0.1415 0.124 0.1059 0.1075 0.135 0.1595 0.1332 0.1242 0.1398 0.0976
Eisosomes 0.0004 0.0001 0.0002 0.0002 0.0003 0.0001 0.0001 0 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0004 0.0003 0.0003 0.0002
Endoplasmic Reticulum 0.0021 0.0003 0.002 0.0004 0.0058 0.0003 0.0011 0.0003 0.0011 0.0003 0.0006 0.0004 0.0006 0.0007 0.0006 0.0006 0.0006 0.0004
Endosome 0.1435 0.1934 0.1056 0.2225 0.156 0.1043 0.1658 0.202 0.134 0.2111 0.1756 0.1343 0.1698 0.1707 0.1331 0.1696 0.1622 0.1224
Golgi 0.3424 0.4027 0.4063 0.4412 0.3798 0.4452 0.3352 0.3892 0.3182 0.3402 0.419 0.4508 0.3372 0.4199 0.312 0.3586 0.4533 0.4085
Lipid Particles 0.0744 0.0581 0.0329 0.0364 0.0645 0.0864 0.0707 0.0252 0.0305 0.0646 0.0794 0.046 0.0961 0.0493 0.0429 0.0295 0.0659 0.1036
Mitochondria 0.0541 0.0409 0.0709 0.0387 0.0717 0.0527 0.0242 0.029 0.056 0.1155 0.0939 0.0323 0.0646 0.0288 0.0637 0.0319 0.0184 0.0384
None 0.0036 0.0001 0.0008 0.0002 0.0079 0.0001 0.0015 0.0002 0.0005 0.0004 0.0002 0.0006 0.0002 0.0002 0.0046 0.0023 0.0006 0.0002
Nuclear Periphery 0.0044 0.0002 0.001 0.0002 0.0318 0.0001 0.0022 0.0001 0.0023 0.0001 0.0002 0.0003 0.0002 0.0002 0.0039 0.001 0.0005 0.0003
Nucleolus 0.001 0.0001 0.0002 0.0001 0.0007 0.0001 0.001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0006 0.0001 0.0004 0.0002 0.0001 0.0001
Nucleus 0.0019 0.0001 0.0002 0.0001 0.0068 0.0001 0.0011 0.0001 0.0004 0.0001 0.0001 0.0001 0.0001 0.0001 0.0005 0.0003 0.0001 0.0001
Peroxisomes 0.2005 0.1152 0.2039 0.0625 0.1087 0.1768 0.164 0.1286 0.2107 0.0871 0.113 0.1835 0.156 0.0935 0.2072 0.1697 0.0953 0.1553
Punctate Nuclear 0.0049 0.0005 0.0008 0.0003 0.0026 0.0003 0.0084 0.0003 0.001 0.0003 0.0002 0.0005 0.0005 0.0007 0.0021 0.0094 0.0047 0.0016
Vacuole 0.0012 0.0015 0.001 0.0016 0.0038 0.0014 0.0024 0.0037 0.0013 0.0013 0.0016 0.0015 0.0018 0.0009 0.0008 0.001 0.0007 0.0008
Vacuole Periphery 0.0015 0.0013 0.0011 0.0016 0.0048 0.0014 0.0013 0.0033 0.001 0.0017 0.0018 0.0014 0.0019 0.0007 0.0011 0.0011 0.0009 0.0011

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 15.3251 13.6997 12.1989 15.2139 19.8696 19.9116 13.5054 21.0352 19.7644 17.2728
Translational Efficiency 0.7224 1.0753 0.9097 0.8663 0.5672 0.623 1.274 0.8242 0.938 1.0137

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1550 1203 2305 1891 1944 2279 2516 1402 3494 3482 4821 3293

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 687.95 853.65 1023.11 973.89 750.53 874.40 989.96 981.02 722.77 867.23 1005.81 976.93
Standard Deviation 95.50 95.94 124.25 141.72 89.84 111.18 122.95 154.07 97.48 106.62 124.68 147.15
Intensity Change Log 2 — 0.311341 0.572586 0.501455 — 0.220384 0.399460 0.386373 — 0.264600 0.484852 0.442557

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.004148 0.008240 0.015212 0.008634 0.002808 0.004342 0.024911 0.005717 0.003403 0.005689 0.020274 0.007392
Bud Neck 0.001166 0.000294 0.000244 0.000940 0.000229 0.000616 0.000191 0.000957 0.000645 0.000505 0.000216 0.000947
Bud Site 0.002887 0.003347 0.001910 0.006198 0.000915 0.003294 0.002952 0.006850 0.001790 0.003313 0.002454 0.006476
Cell Periphery 0.000136 0.000100 0.000067 0.000057 0.000046 0.000055 0.000074 0.000067 0.000086 0.000070 0.000070 0.000061
Cytoplasm 0.003191 0.002386 0.000913 0.003385 0.001491 0.002316 0.001820 0.003640 0.002246 0.002340 0.001386 0.003493
Cytoplasmic Foci 0.152093 0.211022* 0.323888* 0.268693* 0.208287* 0.203375* 0.250238* 0.303514* 0.183358* 0.206017* 0.285451* 0.283518*
Eisosomes 0.000134 0.000121 0.000089 0.000043 0.000091 0.000077 0.000121 0.000041 0.000110 0.000092 0.000106 0.000042
Endoplasmic Reticulum 0.000284 0.000664 0.001106 0.000273 0.000173 0.000276 0.000439 0.000271 0.000222 0.000410 0.000758 0.000272
Endosome 0.126956 0.157363 0.168418 0.298994* 0.128890 0.194495 0.218424* 0.279202* 0.128032 0.181666 0.194515 0.290568*
Golgi 0.527768* 0.538900* 0.414569* 0.287759* 0.556446* 0.485221* 0.431869* 0.276368* 0.543724* 0.503766* 0.423598* 0.282909*
Lipid Particles 0.018191 0.008652 0.021663 0.010530 0.010193 0.010880 0.005218 0.012104 0.013741 0.010110 0.013081 0.011200
Mitochondria 0.115666* 0.038315 0.020787 0.023372 0.050815 0.052896 0.032683 0.015511 0.079584 0.047859 0.026995 0.020025
Mitotic Spindle 0.004906 0.005753 0.010768 0.043700 0.005705 0.008632 0.007677 0.046273 0.005351 0.007637 0.009155 0.044795
None 0.000480 0.000051 0.000030 0.000049 0.000099 0.000234 0.000025 0.000204 0.000268 0.000171 0.000027 0.000115
Nuclear Periphery 0.000026 0.000022 0.000173 0.000262 0.000031 0.000056 0.000056 0.000096 0.000029 0.000044 0.000112 0.000192
Nuclear Periphery Foci 0.000326 0.000125 0.001115 0.001572 0.000163 0.000179 0.000226 0.001062 0.000236 0.000160 0.000651 0.001355
Nucleolus 0.000805 0.000013 0.000012 0.000117 0.000041 0.000093 0.000005 0.000180 0.000380 0.000066 0.000008 0.000144
Nucleus 0.000558 0.000067 0.000023 0.000091 0.000054 0.000085 0.000016 0.000112 0.000278 0.000079 0.000020 0.000100
Peroxisomes 0.034388 0.016246 0.006895 0.016284 0.029889 0.022967 0.013469 0.028299 0.031885 0.020645 0.010325 0.021399
Vacuole 0.002288 0.004166 0.007379 0.021114 0.001598 0.005219 0.005861 0.015244 0.001904 0.004855 0.006587 0.018615
Vacuole Periphery 0.003601 0.004154 0.004739 0.007932 0.002033 0.004690 0.003724 0.004288 0.002729 0.004505 0.004209 0.006381

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.11 -7.24 -2.95 -0.20 3.41 -1.94 -11.11 -3.00 -1.25 8.89 -3.26 -13.31 -4.23 -1.61 8.60
Bud Neck 3.18 3.40 0.55 -4.19 -4.63 -3.46 1.28 -5.83 -2.25 -6.13 1.00 3.52 -2.16 -3.77 -7.17
Bud Site -0.80 2.23 -4.15 -3.53 -5.70 -5.23 -8.26 -7.21 -4.02 -4.72 -4.09 -2.87 -8.30 -5.24 -7.23
Cell Periphery 1.42 3.56 3.91 2.23 1.23 -1.45 -5.68 -2.93 -1.77 0.62 1.45 1.74 2.37 0.88 1.50
Cytoplasm 1.06 3.27 -0.42 -1.86 -4.81 -2.03 -0.93 -3.82 -2.42 -3.16 -0.17 2.32 -2.78 -2.98 -5.38
Cytoplasmic Foci -12.36 -35.50 -22.05 -9.75 9.36 1.20 -9.05 -15.43 -16.47 -8.36 -7.07 -29.75 -24.58 -18.61 0.56
Eisosomes 0.92 5.72 11.84 5.81 10.32 1.84 -3.98 8.22 6.53 14.76 2.52 0.88 13.99 8.47 17.65
Endoplasmic Reticulum -1.24 -5.86 0.28 1.29 6.06 -1.42 -4.31 -2.92 -0.01 2.61 -1.62 -7.18 -1.98 1.17 6.60
Endosome -5.88 -9.33 -27.61* -21.68 -21.89 -13.88 -20.56 -23.75 -12.54 -9.32 -15.03 -21.28 -36.67* -22.89 -21.65
Golgi -1.28 14.31 28.44 29.70* 17.65* 9.90 18.50 36.02* 27.05 21.33* 6.99 23.39 45.79* 38.92 27.46*
Lipid Particles 4.27 -1.35 3.64 -1.10 5.47 -0.47 4.62 -1.08 -0.64 -4.24 2.83 0.56 1.95 -0.88 1.45
Mitochondria 13.22 17.67 16.84 4.30 -0.97 -0.55 5.17 10.75 12.21 6.53 9.24 16.87 19.10 11.72 3.69
Mitotic Spindle -0.61 -3.94 -12.16 -11.55 -9.79 -2.47 -1.69 -10.74 -9.90 -10.19 -2.58 -4.07 -16.18 -14.99 -14.29
None 2.48 2.60 2.46 -0.09 -1.40 -0.54 1.70 -0.64 0.10 -1.74 0.92 3.05 1.79 0.40 -1.99
Nuclear Periphery 0.84 -9.96 -4.30 -4.38 -1.60 -1.12 -2.67 -6.19 -1.94 -4.48 -1.06 -9.48 -5.12 -4.31 -2.49
Nuclear Periphery Foci 1.92 -2.19 -5.01 -6.75 -1.19 -0.30 -0.88 -4.17 -4.12 -3.84 1.48 -2.38 -6.84 -7.73 -3.33
Nucleolus 2.22 2.22 1.93 -4.24 -4.21 -1.45 2.94 -2.16 -1.42 -2.82 2.00 2.36 1.45 -2.35 -4.44
Nucleus 1.26 1.37 1.15 -1.05 -2.53 -0.79 1.34 -1.31 -0.77 -2.36 1.15 1.49 0.93 -1.17 -3.49
Peroxisomes 6.57 11.22 6.78 -0.07 -6.25 2.64 6.92 0.47 -2.02 -6.04 5.79 12.65 5.25 -0.54 -8.05
Vacuole -3.74 -8.70 -15.71 -13.39 -10.61 -8.10 -11.60 -12.08 -8.47 -8.10 -8.63 -13.83 -19.91 -15.54 -13.63
Vacuole Periphery -1.06 -2.94 -5.69 -4.54 -4.23 -5.76 -6.35 -5.59 0.72 -1.29 -4.99 -6.48 -7.89 -3.45 -4.63
Standard name
Human Ortholog
Description Cyclic nucleotide phosphodiesterase; hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Cpd1

Cpd1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cpd1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available