| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 1 | 0 | 2 | 3 |
| Bud | – | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | – | 0 | 0 | 2 | 4 | 5 |
| Bud Neck | – | 0 | 2 | 0 | 0 | 2 | 1 | 5 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | – | 0 | 0 | 0 | 3 | 2 |
| Bud Site | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
| Cell Periphery | – | 0 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | – | 0 | 0 | 0 | 1 | 0 |
| Cytoplasm | – | 13 | 66 | 33 | 37 | 87 | 115 | 147 | 47 | 47 | 27 | 18 | 70 | 113 | 146 | 14 | 30 | 25 | – | 50 | 36 | 47 | 76 | 71 |
| Endoplasmic Reticulum | – | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 3 | 2 | 5 | 3 | – | 0 | 0 | 0 | 0 | 3 |
| Endosome | – | 0 | 2 | 0 | 1 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 2 | 11 | 13 | – | 3 | 2 | 0 | 1 | 2 |
| Golgi | – | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | – | 0 | 1 | 0 | 0 | 2 |
| Mitochondria | – | 10 | 0 | 0 | 0 | 11 | 10 | 25 | 35 | 22 | 36 | 42 | 0 | 0 | 0 | 4 | 20 | 7 | – | 5 | 15 | 2 | 2 | 12 |
| Nucleus | – | 0 | 3 | 4 | 3 | 1 | 3 | 7 | 1 | 4 | 0 | 2 | 4 | 2 | 1 | 30 | 50 | 38 | – | 2 | 6 | 5 | 7 | 6 |
| Nuclear Periphery | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | – | 0 | 0 | 0 | 0 | 1 |
| Nucleolus | – | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4 | 1 | – | 0 | 1 | 1 | 1 | 2 |
| Peroxisomes | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 |
| SpindlePole | – | 0 | 3 | 0 | 0 | 0 | 1 | 5 | 2 | 3 | 1 | 0 | 0 | 1 | 0 | 1 | 2 | 3 | – | 1 | 6 | 4 | 3 | 14 |
| Vac/Vac Membrane | – | 3 | 5 | 3 | 6 | 11 | 3 | 12 | 4 | 3 | 2 | 1 | 6 | 6 | 10 | 3 | 18 | 17 | – | 3 | 3 | 4 | 9 | 15 |
| Unique Cell Count | 21 | 79 | 40 | 46 | 106 | 125 | 179 | 74 | 74 | 57 | 51 | 83 | 126 | 157 | 51 | 114 | 90 | 70 | 82 | 75 | 120 | 153 | ||
| Labelled Cell Count | 26 | 83 | 43 | 49 | 116 | 135 | 203 | 92 | 81 | 69 | 66 | 83 | 127 | 169 | 58 | 141 | 108 | 70 | 82 | 75 | 120 | 153 | ||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | – | 3.4 | 5.0 | 4.7 | 5.8 | 4.2 | 4.1 | 4.7 | 3.6 | 4.1 | 4.0 | 3.7 | 5.3 | 5.4 | 5.1 | 4.9 | 5.9 | 5.6 | 6.4 | 5.4 | 6.4 |
| Std Deviation (1e-4) | – | 1.1 | 1.5 | 1.0 | 2.2 | 1.2 | 1.4 | 2.0 | 2.0 | 1.6 | 1.9 | 1.3 | 1.9 | 1.7 | 1.8 | 2.0 | 2.6 | 1.8 | 2.8 | 2.1 | 3.1 |
| Intensity Change (Log2) | – | – | – | -0.11 | 0.21 | -0.25 | -0.29 | -0.1 | -0.47 | -0.31 | -0.34 | -0.45 | 0.07 | 0.09 | 0.02 | -0.04 | 0.24 | 0.15 | 0.34 | 0.09 | 0.35 |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | 2.0 | 2.4 |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | 0.2766 | 0.0327 | 0.0026 | 0.1921 | 0.3616 | 0.0008 | – | – | – | – | – | – | 0.0428 | 0.0002 | 0.013 | 0.0008 | 0.0004 | 0.0222 |
| Bud | 0.0023 | 0.001 | 0.0033 | 0.0012 | 0.0004 | 0.0001 | – | – | – | – | – | – | 0.0006 | 0.0001 | 0.0006 | 0.0005 | 0.0002 | 0.0007 |
| Bud Neck | 0.0502 | 0.0015 | 0.0009 | 0.0024 | 0.0029 | 0.0096 | – | – | – | – | – | – | 0.0077 | 0.0005 | 0.0009 | 0.0019 | 0.0033 | 0.0292 |
| Bud Periphery | 0.004 | 0.0016 | 0.0025 | 0.0012 | 0.0005 | 0.0001 | – | – | – | – | – | – | 0.0008 | 0.0001 | 0.0009 | 0.0008 | 0.0002 | 0.0014 |
| Bud Site | 0.0128 | 0.0049 | 0.0044 | 0.007 | 0.001 | 0.0001 | – | – | – | – | – | – | 0.0145 | 0.001 | 0.0008 | 0.0014 | 0.0005 | 0.0011 |
| Cell Periphery | 0.0024 | 0.0002 | 0.0001 | 0.0001 | 0.0002 | 0 | – | – | – | – | – | – | 0.0006 | 0.0001 | 0.0002 | 0.0003 | 0 | 0.0002 |
| Cytoplasm | 0.0151 | 0.0663 | 0.0607 | 0.0417 | 0.0124 | 0.1095 | – | – | – | – | – | – | 0.0718 | 0.1056 | 0.0759 | 0.1376 | 0.1218 | 0.1307 |
| Cytoplasmic Foci | 0.0441 | 0.0082 | 0.0096 | 0.023 | 0.0133 | 0.0037 | – | – | – | – | – | – | 0.0201 | 0.0069 | 0.0243 | 0.0152 | 0.0014 | 0.0449 |
| Eisosomes | 0.003 | 0.0003 | 0.0001 | 0.0005 | 0.0011 | 0.0002 | – | – | – | – | – | – | 0.0005 | 0.0002 | 0.0001 | 0.0001 | 0 | 0.0002 |
| Endoplasmic Reticulum | 0.0101 | 0.001 | 0.0033 | 0.0002 | 0.0084 | 0.0014 | – | – | – | – | – | – | 0.003 | 0.0026 | 0.003 | 0.0031 | 0.0025 | 0.0039 |
| Endosome | 0.097 | 0.0014 | 0.0105 | 0.0024 | 0.0296 | 0.0016 | – | – | – | – | – | – | 0.0149 | 0.0026 | 0.0034 | 0.0644 | 0.0018 | 0.0128 |
| Golgi | 0.0332 | 0.0025 | 0.0016 | 0.0159 | 0.0214 | 0.0001 | – | – | – | – | – | – | 0.0047 | 0.0002 | 0.0009 | 0.0077 | 0.0001 | 0.0099 |
| Lipid Particles | 0.06 | 0.0011 | 0.0012 | 0.0207 | 0.0134 | 0.0004 | – | – | – | – | – | – | 0.0161 | 0.0032 | 0.0006 | 0.0061 | 0.0001 | 0.0068 |
| Mitochondria | 0.021 | 0.0143 | 0.0058 | 0.009 | 0.0018 | 0.0004 | – | – | – | – | – | – | 0.0046 | 0.0008 | 0.0013 | 0.0059 | 0.0007 | 0.0323 |
| None | 0.22 | 0.7185 | 0.5676 | 0.2785 | 0.4975 | 0.4463 | – | – | – | – | – | – | 0.2648 | 0.4672 | 0.3608 | 0.4054 | 0.3764 | 0.3563 |
| Nuclear Periphery | 0.0228 | 0.0037 | 0.0344 | 0.0011 | 0.0123 | 0.011 | – | – | – | – | – | – | 0.0223 | 0.012 | 0.009 | 0.0107 | 0.0254 | 0.0132 |
| Nucleolus | 0.0095 | 0.0031 | 0.0038 | 0.0005 | 0.0004 | 0.0049 | – | – | – | – | – | – | 0.0088 | 0.0079 | 0.0076 | 0.0052 | 0.0094 | 0.0073 |
| Nucleus | 0.0093 | 0.117 | 0.2127 | 0.3438 | 0.0013 | 0.3622 | – | – | – | – | – | – | 0.4101 | 0.3394 | 0.4121 | 0.1949 | 0.3453 | 0.279 |
| Peroxisomes | 0.0394 | 0.0016 | 0.0011 | 0.0566 | 0.0059 | 0.0001 | – | – | – | – | – | – | 0.005 | 0.0003 | 0.0002 | 0.0014 | 0.0001 | 0.0039 |
| Punctate Nuclear | 0.0236 | 0.0181 | 0.0682 | 0.0019 | 0.0136 | 0.0468 | – | – | – | – | – | – | 0.08 | 0.0467 | 0.0816 | 0.1117 | 0.1078 | 0.04 |
| Vacuole | 0.0365 | 0.0009 | 0.0035 | 0.0002 | 0.0004 | 0.0007 | – | – | – | – | – | – | 0.0051 | 0.0019 | 0.0024 | 0.0195 | 0.0023 | 0.0029 |
| Vacuole Periphery | 0.0072 | 0.0002 | 0.0022 | 0.0001 | 0.0008 | 0.0002 | – | – | – | – | – | – | 0.0013 | 0.0004 | 0.0006 | 0.0054 | 0.0004 | 0.0011 |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 44.4499 | 51.4225 | 54.3458 | 32.9654 | 38.4209 | 64.4603 | 43.7215 | 43.599 | 58.006 | 43.0006 |
| Translational Efficiency | 0.4862 | 0.4028 | 0.3769 | 0.7953 | 0.7189 | 0.3363 | 0.4389 | 0.6168 | 0.4112 | 0.5059 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | ✘ |
| Gene Expression | ✘ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 31 | 214 | 1749 | 14 | 46 | 199 | 110 | 36 | 77 | 413 | 1859 | 50 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 681.56 | 802.06 | 831.25 | 774.14 | 710.98 | 857.74 | 830.10 | 900.24 | 699.14 | 828.89 | 831.18 | 864.93 |
| Standard Deviation | 109.86 | 144.70 | 110.74 | 89.97 | 119.30 | 146.73 | 115.73 | 304.20 | 116.49 | 148.32 | 111.04 | 268.51 |
| Intensity Change Log 2 | — | 0.234869 | 0.286442 | 0.183754 | — | 0.270731 | 0.223476 | 0.340501 | — | 0.253291 | 0.254637 | 0.265908 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000323 | 0.002257 | 0.000953 | 0.000232 | 0.000636 | 0.002112 | 0.001164 | 0.001530 | 0.000510 | 0.002187 | 0.000966 | 0.001167 |
| Bud Neck | 0.004140 | 0.015872 | 0.030451 | 0.008090 | 0.008065 | 0.011461 | 0.009607 | 0.005792 | 0.006485 | 0.013747 | 0.029217 | 0.006435 |
| Bud Site | 0.009383 | 0.030216 | 0.019525 | 0.004688 | 0.005731 | 0.020130 | 0.016091 | 0.091010 | 0.007201 | 0.025356 | 0.019322 | 0.066840 |
| Cell Periphery | 0.000300 | 0.000366 | 0.000217 | 0.000249 | 0.000259 | 0.000211 | 0.000255 | 0.000266 | 0.000276 | 0.000291 | 0.000220 | 0.000261 |
| Cytoplasm | 0.263779* | 0.171947* | 0.078893 | 0.522783* | 0.155001* | 0.115988* | 0.238291* | 0.235885* | 0.198795* | 0.144984* | 0.088325 | 0.316217* |
| Cytoplasmic Foci | 0.041304 | 0.028467 | 0.001597 | 0.126783 | 0.014569 | 0.052957 | 0.009928 | 0.012324 | 0.025333 | 0.040267 | 0.002090 | 0.044372 |
| Eisosomes | 0.000116 | 0.000083 | 0.000039 | 0.000131 | 0.000082 | 0.000091 | 0.000068 | 0.000064 | 0.000096 | 0.000087 | 0.000041 | 0.000083 |
| Endoplasmic Reticulum | 0.004253 | 0.010488 | 0.005699 | 0.002150 | 0.004854 | 0.005721 | 0.011566 | 0.006015 | 0.004612 | 0.008191 | 0.006046 | 0.004933 |
| Endosome | 0.005430 | 0.013433 | 0.001523 | 0.015803 | 0.002810 | 0.019303 | 0.005524 | 0.002180 | 0.003865 | 0.016261 | 0.001760 | 0.005995 |
| Golgi | 0.000982 | 0.007850 | 0.000401 | 0.000349 | 0.000287 | 0.011629 | 0.000690 | 0.001031 | 0.000567 | 0.009671 | 0.000418 | 0.000840 |
| Lipid Particles | 0.007464 | 0.006633 | 0.000773 | 0.007791 | 0.003457 | 0.005588 | 0.002339 | 0.002046 | 0.005070 | 0.006130 | 0.000866 | 0.003655 |
| Mitochondria | 0.004192 | 0.010407 | 0.005778 | 0.000518 | 0.001312 | 0.020167 | 0.001093 | 0.000841 | 0.002471 | 0.015110 | 0.005501 | 0.000750 |
| Mitotic Spindle | 0.003069 | 0.047751 | 0.033187 | 0.003255 | 0.058889 | 0.110457* | 0.023054 | 0.016188 | 0.036416 | 0.077965 | 0.032587 | 0.012567 |
| None | 0.040499 | 0.035785 | 0.008871 | 0.021706 | 0.016406 | 0.020853 | 0.017071 | 0.004772 | 0.026106 | 0.028590 | 0.009356 | 0.009514 |
| Nuclear Periphery | 0.002104 | 0.002593 | 0.002767 | 0.001760 | 0.002162 | 0.002991 | 0.003403 | 0.005518 | 0.002139 | 0.002785 | 0.002805 | 0.004466 |
| Nuclear Periphery Foci | 0.001701 | 0.004782 | 0.000607 | 0.003255 | 0.001504 | 0.005816 | 0.005929 | 0.007725 | 0.001583 | 0.005280 | 0.000922 | 0.006473 |
| Nucleolus | 0.009954 | 0.010076 | 0.006312 | 0.004631 | 0.015560 | 0.010327 | 0.001565 | 0.000863 | 0.013303 | 0.010197 | 0.006032 | 0.001918 |
| Nucleus | 0.499630* | 0.551229* | 0.786755* | 0.139744* | 0.685983* | 0.491856* | 0.554851* | 0.455956* | 0.610957* | 0.522621* | 0.773033* | 0.367417* |
| Peroxisomes | 0.001463 | 0.004724 | 0.000351 | 0.001568 | 0.001341 | 0.025240 | 0.000391 | 0.000379 | 0.001390 | 0.014610 | 0.000353 | 0.000712 |
| Vacuole | 0.069212 | 0.039823 | 0.013523 | 0.134018 | 0.020576 | 0.063973 | 0.096405 | 0.073091 | 0.040157 | 0.051460 | 0.018427 | 0.090151 |
| Vacuole Periphery | 0.030702 | 0.005217 | 0.001778 | 0.000496 | 0.000516 | 0.003130 | 0.000716 | 0.076523 | 0.012669 | 0.004211 | 0.001715 | 0.055235 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | NaN | NaN | NaN | NaN | NaN | -0.16 | 0.13 | -0.94 | -0.94 | -1.32 | -1.63 | -0.42 | -1.13 | 0.06 | -1.06 |
| Bud Neck | NaN | NaN | NaN | NaN | NaN | 0.23 | 0.48 | 0.61 | 0.41 | 0.22 | -2.30 | -7.22 | -0.01 | 2.09 | 6.60 |
| Bud Site | NaN | NaN | NaN | NaN | NaN | -1.00 | 0.07 | -1.80 | -1.63 | -1.81 | -2.07 | -1.54 | -1.76 | -1.36 | -1.57 |
| Cell Periphery | NaN | NaN | NaN | NaN | NaN | 1.28 | 1.04 | 0.11 | -1.67 | -1.31 | 0.76 | 1.83 | 0.32 | -0.47 | -1.81 |
| Cytoplasm | NaN | NaN | NaN | NaN | NaN | -0.41 | -0.46 | -0.70 | -0.49 | -0.38 | 0.97 | 3.39 | -1.00 | -2.10 | -4.22 |
| Cytoplasmic Foci | NaN | NaN | NaN | NaN | NaN | -2.20 | 1.01 | 0.39 | 2.77 | -0.64 | -0.17 | 3.70 | -0.67 | -0.62 | -2.78 |
| Eisosomes | NaN | NaN | NaN | NaN | NaN | -0.06 | 0.75 | -0.12 | -0.09 | -0.84 | 1.18 | 4.15 | -0.48 | -1.50 | -3.76 |
| Endoplasmic Reticulum | NaN | NaN | NaN | NaN | NaN | -0.61 | -3.19 | -1.45 | -1.24 | 0.47 | -2.11 | -0.56 | -1.21 | -0.15 | -1.06 |
| Endosome | NaN | NaN | NaN | NaN | NaN | -3.72 | -1.54 | -0.83 | 2.85 | 0.38 | -3.43 | 3.90 | -1.43 | 0.95 | -2.80 |
| Golgi | NaN | NaN | NaN | NaN | NaN | -1.82 | 0.62 | -0.50 | 1.75 | -0.86 | -2.47 | 1.52 | 0.15 | 2.49 | -1.15 |
| Lipid Particles | NaN | NaN | NaN | NaN | NaN | -1.43 | 1.12 | -0.22 | 1.21 | -1.41 | -0.36 | 3.47 | -0.21 | 0.11 | -3.39 |
| Mitochondria | NaN | NaN | NaN | NaN | NaN | -2.18 | 0.40 | 0.87 | 2.26 | 0.68 | -2.53 | -2.69 | 1.74 | 3.21 | 6.88 |
| Mitotic Spindle | NaN | NaN | NaN | NaN | NaN | -0.51 | 0.99 | 0.21 | 0.80 | -0.73 | -1.26 | 0.43 | -0.07 | 1.03 | -0.47 |
| None | NaN | NaN | NaN | NaN | NaN | -0.23 | 0.73 | 2.34 | 1.82 | 1.93 | 0.42 | 1.38 | 1.43 | 2.45 | 0.37 |
| Nuclear Periphery | NaN | NaN | NaN | NaN | NaN | -1.91 | -1.82 | -1.56 | -0.36 | -0.74 | -2.24 | -1.78 | -1.28 | 0.05 | -0.51 |
| Nuclear Periphery Foci | NaN | NaN | NaN | NaN | NaN | -0.12 | 0.49 | -0.74 | -0.79 | -1.32 | -0.69 | 1.09 | -0.96 | -0.63 | -1.86 |
| Nucleolus | NaN | NaN | NaN | NaN | NaN | 1.07 | 2.68 | 2.57 | 2.76 | -0.72 | 0.71 | 1.91 | 2.88 | 4.03 | 4.17 |
| Nucleus | NaN | NaN | NaN | NaN | NaN | 2.26 | 0.78 | 2.66 | 1.21 | 2.38 | 0.72 | -5.10 | 3.58 | 3.73 | 8.83 |
| Peroxisomes | NaN | NaN | NaN | NaN | NaN | -2.55 | 3.03 | 1.98 | 2.81 | -1.92 | -2.96 | 3.88 | 1.02 | 3.19 | -2.19 |
| Vacuole | NaN | NaN | NaN | NaN | NaN | -1.43 | -2.53 | -2.48 | -1.80 | -0.81 | -0.11 | 2.88 | -3.25 | -3.48 | -5.09 |
| Vacuole Periphery | NaN | NaN | NaN | NaN | NaN | -1.40 | 1.17 | -0.99 | -0.94 | -1.00 | 0.81 | 1.01 | -0.40 | -0.88 | -0.98 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance |
| Localization | |
| Cell Percentages | nucleus (63%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | nucleus-3 |
Srb2
Srb2
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Srb2-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
