Standard name
Human Ortholog
Description U2B component of U2 snRNP; involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0.06
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0.05 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.5 0.34 0.39 0.33 0.38 0.25 0.22 0.21 0.21 0.56 0.66 0.65 0.11 0.18 0.13 0.36 0.08 0.25 0.23 0.31 0.28
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.05 0 0 0 0 0 0 0
Endosome 0 0 0.16 0 0.08 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.41 0.51 0.12 0.49 0.37 0.75 0.57 0.69 0.79 0 0 0 0.09 0.09 0.07 0 0 0.08 0.07 0.09 0.05
Nucleus 0.19 0.2 0.27 0.31 0.26 0.15 0.33 0.17 0.17 0.32 0.18 0.22 0.69 0.67 0.73 0.33 0.4 0.23 0.32 0.2 0.24
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0 0.08 0 0.05
Vac/Vac Membrane 0.09 0.07 0.14 0.09 0 0.11 0 0.07 0.06 0.12 0.13 0.09 0.14 0.12 0.09 0.13 0.15 0.19 0.17 0.24 0.22
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1
Bud 0 0 0 0 1 0 1 1 0 0 0 1 1 0 0 2 1 2 1 2 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 1
Bud Site 0 2 0 0 1 1 3 0 1 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Cytoplasm 16 14 19 15 28 14 13 12 18 19 55 83 18 37 20 23 2 19 13 26 26
Endoplasmic Reticulum 0 0 0 0 1 1 0 0 0 0 1 0 11 10 5 0 0 1 0 0 0
Endosome 0 0 8 0 6 0 1 0 2 0 2 3 5 1 2 0 1 3 0 2 2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 1 0 0 2 0
Mitochondria 13 21 6 22 27 41 33 40 66 1 3 3 15 18 11 2 1 6 4 7 5
Nucleus 6 8 13 14 19 8 19 10 14 11 15 28 111 138 115 21 12 17 19 16 23
Nuclear Periphery 0 0 0 0 1 1 0 1 0 0 0 0 2 1 0 0 0 0 0 0 0
Nucleolus 0 2 1 0 1 1 0 1 0 0 1 1 1 3 1 1 0 0 0 0 1
Peroxisomes 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 0 0 0 0 1 1 0 0 2 0 2 1 2 3 2 4 1 4
Vac/Vac Membrane 3 3 7 4 3 6 1 4 5 4 11 11 23 24 14 8 4 14 10 20 20
Unique Cell Count 32 41 49 45 73 55 58 58 84 34 83 128 161 205 157 66 31 76 60 85 95
Labelled Cell Count 38 50 55 55 89 73 72 70 107 35 89 132 189 235 170 66 31 76 60 85 95


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.5 3.8 5.0 3.3 4.5 3.4 4.5 3.9 3.4 4.4 4.5 4.6 6.9 6.7 6.9 4.3 4.3 4.3
Std Deviation (1e-4) 1.2 2.6 2.8 0.7 3.3 1.7 3.3 2.1 1.5 1.2 1.6 1.4 1.6 3.0 2.4 1.7 1.1 1.1
Intensity Change (Log2) 0.13 0.51 -0.06 0.37 -0.04 0.36 0.15 -0.04 0.32 0.38 0.39 0.99 0.94 0.98 0.31 0.3 0.3

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.4 -1.0 -1.5 -1.1 -2.3 -2.7 -2.9 -3.0 0.5 1.6 1.5 -5.3 -4.0 -4.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 -2.9 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.1 0.8 1.2 0.8 -0.5 1.4 -0.2 -0.3 1.3 -0.1 0.4 5.3 5.2 5.9
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration
Actin 0.0433 0.0198 0.0043 0.0684 0.0024 0.0038 0.1033 0.0005 0.0512 0.009 0.0102 0.0188
Bud 0.001 0.0003 0.0002 0.0014 0.0001 0.0005 0.001 0.0038 0.0008 0.0003 0.0007 0.0001
Bud Neck 0.002 0.0025 0.0004 0.0093 0.0008 0.0023 0.0022 0.0006 0.0104 0.0008 0.0011 0.0053
Bud Periphery 0.0008 0.0003 0.0001 0.002 0.0001 0.0025 0.0015 0.003 0.0009 0.0004 0.0021 0.0001
Bud Site 0.0064 0.0164 0.001 0.0045 0.0002 0.0001 0.0063 0.0064 0.0108 0.0019 0.0017 0.0003
Cell Periphery 0.0003 0.0003 0 0.0004 0.0001 0 0.001 0.0001 0.0004 0.0001 0.0004 0.0001
Cytoplasm 0.1201 0.1604 0.0817 0.1299 0.0781 0.0972 0.0277 0.0822 0.1227 0.0841 0.0868 0.0748
Cytoplasmic Foci 0.0724 0.0032 0.0172 0.0074 0.0023 0.0082 0.0877 0.0173 0.0416 0.0105 0.0195 0.0021
Eisosomes 0.0017 0.0002 0.0001 0.0004 0.0001 0.0001 0.0016 0.0001 0.0003 0.0002 0.0006 0.0003
Endoplasmic Reticulum 0.0236 0.0038 0.0054 0.0046 0.0111 0.0022 0.0164 0.0041 0.008 0.0027 0.0119 0.0093
Endosome 0.0625 0.0021 0.0103 0.0219 0.0172 0.0036 0.1039 0.0041 0.0423 0.0285 0.1279 0.0032
Golgi 0.035 0.0006 0.0058 0.0194 0.0005 0.0018 0.0476 0.001 0.0105 0.0094 0.0142 0.0005
Lipid Particles 0.0657 0.0007 0.016 0.0285 0.001 0.0007 0.0597 0.0008 0.0108 0.0099 0.1348 0.0005
Mitochondria 0.0076 0.0006 0.0021 0.0062 0.0014 0.0279 0.0492 0.001 0.0073 0.0178 0.1297 0.0005
None 0.16 0.4413 0.3209 0.1876 0.4232 0.0629 0.0414 0.2789 0.2545 0.16 0.0333 0.0944
Nuclear Periphery 0.0786 0.0085 0.0259 0.0103 0.0681 0.0124 0.086 0.0367 0.0578 0.0093 0.0874 0.0199
Nucleolus 0.0032 0.0031 0.0041 0.0022 0.0037 0.0047 0.0067 0.0066 0.002 0.0026 0.0112 0.0073
Nucleus 0.2503 0.3072 0.4289 0.4805 0.3659 0.6957 0.2691 0.5228 0.3124 0.6254 0.2154 0.7308
Peroxisomes 0.0301 0.0004 0.0186 0.0025 0.0001 0.0007 0.0282 0.0018 0.0242 0.0034 0.0131 0.0003
Punctate Nuclear 0.03 0.0264 0.0552 0.0093 0.019 0.0713 0.0497 0.0241 0.0166 0.0174 0.0667 0.0295
Vacuole 0.0033 0.0017 0.0015 0.0022 0.0029 0.0007 0.0049 0.0031 0.0113 0.0049 0.0142 0.0015
Vacuole Periphery 0.0024 0.0002 0.0005 0.0012 0.002 0.0005 0.0048 0.0007 0.0033 0.0014 0.0173 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 14.7777 14.6782 6.5351 13.5715 6.3867 9.8464 14.0991 11.0184 18.8232 15.1894
Translational Efficiency 2.4595 1.3041 2.6007 1.8317 4.0732 4.9322 1.8461 2.0893 1.307 1.9556

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
37 91 1593 115 75 693 2350 82 112 784 3943 197

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 697.81 823.42 854.37 860.56 597.88 755.68 867.97 952.23 630.89 763.54 862.48 898.72
Standard Deviation 89.79 146.83 112.84 121.83 118.34 102.08 132.76 149.56 119.37 110.38 125.27 141.48
Intensity Change Log 2 0.238794 0.292027 0.302442 0.337919 0.537789 0.671454 0.285382 0.410649 0.484491

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000105 0.001627 0.000384 0.000845 0.000064 0.000641 0.000603 0.001295 0.000077 0.000755 0.000514 0.001033
Bud Neck 0.001880 0.012613 0.010551 0.009804 0.003434 0.013422 0.033689 0.010042 0.002921 0.013328 0.024341 0.009903
Bud Site 0.000393 0.009169 0.008168 0.007392 0.001085 0.006597 0.015919 0.031016 0.000856 0.006895 0.012788 0.017225
Cell Periphery 0.000157 0.000321 0.000171 0.000230 0.000352 0.000227 0.000228 0.000731 0.000288 0.000238 0.000205 0.000438
Cytoplasm 0.170781 0.193236 0.090057 0.214406 0.237920 0.227978 0.107406 0.197955 0.215741 0.223946 0.100397 0.207559
Cytoplasmic Foci 0.123169 0.122972 0.001667 0.014288 0.128604 0.078277 0.000924 0.012732 0.126808 0.083465 0.001224 0.013640
Eisosomes 0.000095 0.000197 0.000025 0.000055 0.000481 0.000079 0.000023 0.000055 0.000354 0.000092 0.000024 0.000055
Endoplasmic Reticulum 0.001250 0.004801 0.004553 0.007164 0.001773 0.001215 0.005257 0.007634 0.001600 0.001632 0.004973 0.007360
Endosome 0.001027 0.010192 0.001138 0.007862 0.002910 0.010511 0.001938 0.022835 0.002288 0.010474 0.001615 0.014094
Golgi 0.000146 0.000624 0.000087 0.006155 0.001274 0.004014 0.000802 0.027503 0.000901 0.003621 0.000513 0.015041
Lipid Particles 0.006150 0.011642 0.000590 0.001886 0.015990 0.005218 0.000414 0.001323 0.012739 0.005963 0.000485 0.001652
Mitochondria 0.000710 0.001839 0.001263 0.011037 0.001008 0.012722 0.007972 0.015547 0.000910 0.011459 0.005261 0.012914
Mitotic Spindle 0.000062 0.002975 0.008522 0.110306 0.000469 0.004905 0.030741 0.142914 0.000335 0.004681 0.021764 0.123879
None 0.002486 0.003951 0.007615 0.007730 0.015589 0.003983 0.007733 0.013044 0.011260 0.003979 0.007685 0.009942
Nuclear Periphery 0.000861 0.001678 0.002327 0.003358 0.001514 0.001770 0.004051 0.001787 0.001298 0.001759 0.003355 0.002704
Nuclear Periphery Foci 0.000336 0.002044 0.000316 0.001541 0.000437 0.000723 0.000545 0.001535 0.000404 0.000876 0.000453 0.001539
Nucleolus 0.002022 0.002992 0.001385 0.001600 0.002274 0.003642 0.002190 0.001236 0.002191 0.003566 0.001865 0.001448
Nucleus 0.675944 0.510066 0.848033 0.546431 0.559481 0.586159 0.754897 0.393979 0.597956 0.577326 0.792525 0.482974
Peroxisomes 0.002057 0.031533 0.000777 0.000734 0.008978 0.007367 0.000284 0.001331 0.006692 0.010172 0.000483 0.000983
Vacuole 0.010247 0.074908 0.012128 0.045201 0.016205 0.029331 0.022851 0.093980 0.014237 0.034621 0.018519 0.065505
Vacuole Periphery 0.000121 0.000620 0.000242 0.001974 0.000157 0.001219 0.001533 0.021526 0.000145 0.001150 0.001012 0.010112

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.76 -3.87 -3.80 0.68 -2.34 -1.66 -7.83 -6.50 -3.21 -4.51 -2.11 -8.91 -7.27 -2.32 -4.60
Bud Neck -3.00 -9.64 -4.54 0.72 0.68 -4.78 -15.07 -4.38 -0.55 5.62 -5.84 -16.90 -5.83 0.19 5.75
Bud Site -3.81 -5.72 -5.18 1.02 -0.53 -2.95 -9.00 -4.60 -2.45 -0.88 -3.80 -10.47 -6.50 -1.80 -0.50
Cell Periphery -1.63 -0.17 -0.95 1.01 -1.00 0.91 1.40 0.28 -0.83 -1.59 0.54 1.36 0.37 -0.29 -1.85
Cytoplasm 0.43 2.67 0.80 0.61 -3.35 0.09 5.27 3.33 4.74 -1.19 -0.15 5.84 2.91 4.71 -3.36
Cytoplasmic Foci 0.34 3.47 3.16 5.45 -2.93 2.33 6.22 5.96 13.34 -2.37 2.32 7.07 6.57 13.64 -3.72
Eisosomes -3.33 3.99 0.65 4.06 -5.00 1.48 1.68 1.34 -2.61 -6.84 1.43 1.80 1.40 -0.47 -8.44
Endoplasmic Reticulum -4.95 -12.96 -6.45 -2.02 -1.65 0.41 -5.95 -4.59 -4.88 -2.99 -0.60 -8.99 -6.73 -6.94 -3.40
Endosome -3.88 -0.82 -2.15 1.84 -2.02 -3.32 1.97 -1.68 1.07 -2.66 -4.24 1.79 -2.22 2.02 -3.28
Golgi -2.15 0.74 -1.19 -0.80 -1.21 -1.54 0.85 -1.12 -0.38 -1.38 -1.86 0.92 -1.42 -0.05 -1.80
Lipid Particles -1.35 2.15 1.49 2.97 -2.39 1.39 2.00 1.77 4.08 -4.11 1.28 2.29 1.98 5.08 -4.14
Mitochondria -1.86 -2.93 -1.15 -0.88 -0.88 -3.70 -6.00 -1.25 2.06 0.66 -3.77 -6.47 -1.56 1.85 -0.13
Mitotic Spindle -1.80 -6.39 -4.05 -3.36 -3.49 0.86 -0.23 -2.22 -3.28 -2.52 0.55 -0.53 -3.82 -4.85 -4.17
None -1.01 -4.45 -2.13 -1.61 -0.35 1.28 0.95 0.90 -1.11 -0.04 1.19 0.71 0.59 -1.86 -0.29
Nuclear Periphery -4.01 -11.09 -4.80 -3.09 -1.10 -1.03 -7.82 -3.72 -3.86 2.72 -2.01 -9.75 -5.23 -4.58 1.09
Nuclear Periphery Foci -2.47 -1.07 -3.28 0.38 -3.03 0.70 1.24 -1.37 -1.66 -1.84 -0.18 0.93 -2.31 -2.31 -3.00
Nucleolus -1.58 -0.10 -0.45 1.20 -0.43 -1.24 0.84 0.34 1.96 -0.63 -1.96 0.82 0.26 2.46 -0.63
Nucleus 2.87 -3.16 1.83 -1.44 8.67 -1.25 -6.44 0.29 1.61 6.69 0.18 -7.13 1.00 1.23 10.53
Peroxisomes -2.24 1.36 1.43 2.40 0.02 0.27 1.69 1.60 4.11 -2.54 -0.71 1.82 1.74 4.74 -1.39
Vacuole -5.73 -1.35 -5.32 0.71 -5.12 -0.16 0.01 -4.97 -5.59 -5.74 -1.89 -0.14 -6.31 -5.98 -7.45
Vacuole Periphery -3.14 -2.44 -1.25 -0.24 -1.05 -3.15 -3.43 -1.47 -1.09 -1.22 -3.41 -3.76 -1.76 -0.91 -1.37
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description U2B component of U2 snRNP; involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members
Localization
Cell Percentages nucleus (47%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Msl1

Msl1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Msl1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available