Standard name
Human Ortholog
Description Protein required for ubiquinone biosynthesis and respiratory growth; localizes to matrix face of mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; ubiquinone is also known as coenzyme Q; human homolog COQ9 can complement yeast coq9 null mutant
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0.05 0 0.06 0 0 0 – 0.07 0.06 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.06 0 0 0 0 0 – 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.09 0 0.2 0.1 0.21 0.17 0.18 – 0 0.07 0 0.06 0.17 0.22 0.27 0.18 0.21 0.24 0.22 0.26 0.15 0.22 0.21 0.12
Golgi 0 0 0.1 0.05 0.07 0 0 – 0 0 0 0 0.05 0 0 0 0 0 0.06 0 0.05 0.07 0.07 0
Mitochondria 0.73 0.86 0.45 0.73 0.33 0.52 0.55 – 0.78 0.79 0.81 0.73 0.46 0.28 0.19 0 0.12 0.07 0.38 0.39 0.5 0.41 0.29 0.29
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0.05 – 0 0.05 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.14 0 0 0 0 0.07 0.07 – 0.09 0.05 0.05 0.05 0 0 0 0 0 0.05 0 0 0 0 0 0
Peroxisomes 0.17 0.09 0.19 0.22 0.28 0.29 0.27 – 0.2 0.17 0.15 0.27 0.31 0.41 0.52 0.84 0.7 0.75 0.22 0.14 0.21 0.16 0.22 0.36
SpindlePole 0.13 0.06 0.25 0.14 0.34 0.21 0.2 – 0.11 0.09 0.09 0.12 0.25 0.39 0.44 0.21 0.31 0.37 0.06 0.05 0 0 0.09 0.09
Vac/Vac Membrane 0 0.08 0.07 0 0.09 0.06 0.06 – 0 0 0 0 0.07 0 0 0 0 0 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 8 4 2 2 0 – 1 6 5 4 0 3 1 0 2 1 0 0 3 6 6 11
Bud 2 7 8 11 10 12 17 – 24 26 16 20 7 6 9 8 6 5 1 2 1 0 1 2
Bud Neck 0 1 1 0 0 0 0 – 1 0 0 0 0 2 1 0 1 0 0 1 0 0 1 2
Bud Site 2 1 0 0 2 2 2 – 5 6 6 7 0 2 0 1 2 3 – – – – – –
Cell Periphery 1 3 6 7 3 3 1 – 0 0 5 2 3 1 1 0 0 6 0 0 0 0 0 0
Cytoplasm 2 9 12 4 12 10 11 – 6 9 2 4 9 17 14 7 6 10 0 1 0 0 1 2
Endoplasmic Reticulum 0 1 0 3 0 1 0 – 0 0 0 1 0 2 0 3 3 1 0 0 2 0 0 0
Endosome 9 3 58 19 69 52 75 – 14 29 16 24 32 78 96 36 32 77 28 39 51 40 41 37
Golgi 0 0 28 10 23 0 1 – 0 0 0 2 9 6 3 1 0 1 7 6 17 12 12 14
Mitochondria 75 120 127 138 109 158 232 – 270 335 300 312 88 97 69 9 19 21 48 60 178 74 56 93
Nucleus 1 0 0 1 4 4 5 – 0 5 1 3 1 0 0 0 2 4 0 1 0 0 1 0
Nuclear Periphery 2 3 3 0 3 4 20 – 9 22 27 10 1 0 1 1 2 2 0 0 0 0 0 1
Nucleolus 14 1 3 1 10 21 31 – 30 21 19 23 3 10 3 3 4 17 0 0 0 1 0 1
Peroxisomes 17 12 53 41 90 89 116 – 68 74 56 114 59 144 184 171 109 241 27 22 75 29 43 114
SpindlePole 13 9 72 27 112 65 83 – 38 40 35 51 48 137 156 42 49 119 7 7 12 6 18 29
Vac/Vac Membrane 3 11 19 7 29 17 24 – 8 4 6 6 14 12 15 3 1 5 1 7 2 4 4 7
Unique Cell Count 103 139 283 188 326 306 424 345 425 369 425 190 350 356 204 156 323 127 155 353 181 194 322
Labelled Cell Count 141 182 398 273 478 440 618 474 577 494 583 274 517 553 285 238 513 127 155 353 181 194 322


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 4.5 6.8 6.5 7.6 6.5 6.9 – 6.6 6.2 6.7 6.9 6.8 6.7 6.3 5.3 6.6 7.1 7.4 8.1 7.4
Std Deviation (1e-4) 1.1 0.9 1.3 1.3 1.7 1.5 1.6 – 1.8 1.9 1.8 1.9 1.6 1.5 1.5 1.0 1.4 1.6 2.0 3.2 2.0
Intensity Change (Log2) – – – -0.05 0.18 -0.05 0.02 – -0.04 -0.13 -0.01 0.02 0.02 -0.01 -0.1 -0.36 -0.03 0.07 0.12 0.25 0.14


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – -2.7 -2.9 -3.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.7458 2.6236 2.444 2.611 2.072 2.7388 5.6727 5.5167 5.4081 5.1102 4.15 5.5652 2.004 2.473 2.2556 2.3646 1.7156 1.8305
Actin 0.0549 0.0173 0.0241 0.015 0.0096 0.0175 0.0465 0.0271 0.0533 0.0078 0.0037 0.0092 0.0528 0.0038 0.0182 0.0037 0.0044 0.0215
Bud 0.0013 0.001 0.0005 0.002 0.0001 0.0001 0.0033 0.0009 0.0018 0.0008 0.0002 0.0003 0.0006 0.0023 0.0029 0.0002 0.0001 0.0019
Bud Neck 0.0073 0.0032 0.0005 0.0046 0.0001 0.0004 0.005 0.0008 0.001 0.0017 0.0002 0.009 0.0035 0.0019 0.0008 0.0004 0.0002 0.0008
Bud Periphery 0.002 0.0013 0.0009 0.004 0.0002 0.0003 0.0071 0.0014 0.0026 0.0016 0.0003 0.0007 0.0008 0.0025 0.0039 0.0002 0.0002 0.0026
Bud Site 0.0082 0.0151 0.0012 0.0071 0.0002 0.0003 0.0118 0.015 0.0106 0.0032 0.0017 0.0016 0.0033 0.0226 0.0081 0.0008 0.0003 0.0014
Cell Periphery 0.0007 0.0006 0.0002 0.0018 0.0001 0.0001 0.0011 0.0005 0.0004 0.0082 0.0001 0.0002 0.0007 0.0007 0.0004 0.0001 0 0.0002
Cytoplasm 0.0076 0.0017 0.0003 0.0004 0.0019 0.0001 0.0155 0.0018 0.0017 0.0006 0.0009 0.0003 0.002 0.0023 0.0005 0.0001 0 0.0005
Cytoplasmic Foci 0.0292 0.0768 0.0276 0.021 0.0875 0.0225 0.0904 0.1242 0.0897 0.0697 0.1714 0.0807 0.1866 0.1721 0.2004 0.0891 0.0822 0.1217
Eisosomes 0.0005 0.0002 0.0007 0.0004 0.0001 0.0002 0.0013 0.0002 0.0004 0.0016 0.0001 0.0001 0.0009 0.0001 0.0002 0.0001 0.0001 0.0002
Endoplasmic Reticulum 0.0151 0.0004 0.0002 0.0001 0.008 0.0002 0.0036 0.0006 0.0009 0.0002 0.0003 0.0002 0.003 0.0007 0.0002 0 0 0.0003
Endosome 0.0776 0.079 0.0491 0.0265 0.0676 0.0198 0.0392 0.0547 0.0251 0.0413 0.0498 0.0186 0.0368 0.0514 0.0364 0.0111 0.0095 0.0277
Golgi 0.083 0.0879 0.0543 0.0549 0.0293 0.0789 0.0277 0.0741 0.0405 0.0509 0.0448 0.0301 0.0319 0.0392 0.0597 0.0196 0.0252 0.0392
Lipid Particles 0.0756 0.053 0.0352 0.0388 0.0232 0.0464 0.1877 0.1433 0.1432 0.1595 0.1889 0.1647 0.2043 0.1595 0.1207 0.1156 0.205 0.1589
Mitochondria 0.4674 0.503 0.6393 0.6625 0.6071 0.593 0.171 0.2069 0.1361 0.1821 0.1197 0.1749 0.2058 0.222 0.2686 0.2746 0.2276 0.2804
None 0.0069 0.0002 0.0002 0.0003 0.0009 0.0001 0.0129 0.0002 0.0038 0.0003 0.0002 0.0002 0.0021 0.0004 0.0002 0.0001 0 0.0003
Nuclear Periphery 0.0093 0.0003 0.0001 0.0001 0.0086 0.0003 0.0119 0.0002 0.0014 0.0001 0.0002 0.0002 0.0045 0.0005 0.004 0.0001 0 0.0004
Nucleolus 0.002 0.0014 0.0128 0.0033 0.0001 0.0001 0.0029 0.0004 0.0021 0.0021 0.0002 0.001 0.0115 0.0057 0.0085 0.0008 0.0002 0.004
Nucleus 0.0067 0.0004 0.0022 0.0005 0.0006 0.0001 0.0072 0.0002 0.0004 0.0002 0.0001 0.0002 0.0065 0.0011 0.004 0.0001 0 0.0017
Peroxisomes 0.1298 0.1464 0.1432 0.1471 0.1497 0.2137 0.3233 0.3383 0.4791 0.4645 0.4121 0.4939 0.2263 0.2748 0.2481 0.4659 0.3929 0.3044
Punctate Nuclear 0.0028 0.0008 0.0006 0.0002 0.001 0.0003 0.0219 0.0008 0.0023 0.0009 0.0015 0.0104 0.0079 0.0124 0.0089 0.0154 0.0511 0.0257
Vacuole 0.0062 0.0055 0.0032 0.0063 0.0011 0.0006 0.0047 0.0052 0.0022 0.0016 0.0025 0.0019 0.0055 0.0135 0.0032 0.0009 0.0004 0.0022
Vacuole Periphery 0.0059 0.0044 0.0037 0.0031 0.0028 0.0048 0.004 0.003 0.0013 0.0013 0.0011 0.0016 0.0024 0.0104 0.0021 0.0011 0.0004 0.0041

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.3656 10.0779 18.6956 27.1566 21.9251 15.4926 26.4297 28.3693 25.5784 24.7237
Translational Efficiency 0.9705 2.622 1.4829 0.9871 1.0459 1.6528 1.3894 1.232 1.5888 1.3102

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
55 1197 157 1624 2093 1832 2054 1667 2148 3029 2211 3291

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 951.76 820.18 1131.13 973.56 752.39 816.20 877.77 997.73 757.49 817.77 895.76 985.80
Standard Deviation 175.55 144.88 156.45 174.15 115.62 132.50 145.89 190.62 121.68 137.54 160.45 183.08
Intensity Change Log 2 — -0.214657 0.249095 0.032672 — 0.117442 0.222362 0.407169 — -0.058545 0.237353 0.210088

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.015528 0.005020 0.018203 0.006897 0.003150 0.004042 0.005089 0.013066 0.003467 0.004429 0.006020 0.010022
Bud Neck 0.003790 0.005787 0.020026 0.017135 0.009414 0.005816 0.023310 0.011740 0.009270 0.005804 0.023077 0.014402
Bud Site 0.023215 0.010627 0.037044 0.111303* 0.036283 0.013034 0.100316* 0.072249 0.035948 0.012083 0.095823 0.091521
Cell Periphery 0.000295 0.000300 0.000551 0.000544 0.000698 0.000759 0.000487 0.000718 0.000688 0.000578 0.000492 0.000632
Cytoplasm 0.014055 0.005320 0.007047 0.024975 0.013422 0.005474 0.027335 0.016298 0.013439 0.005413 0.025894 0.020580
Cytoplasmic Foci 0.093873 0.095918 0.236993* 0.156372 0.176167 0.080249 0.197520* 0.150305 0.174060 0.086441 0.200323* 0.153299
Eisosomes 0.000301 0.000145 0.000308 0.000132 0.000226 0.000141 0.000127 0.000207 0.000228 0.000142 0.000140 0.000170
Endoplasmic Reticulum 0.009701 0.000298 0.001895 0.001196 0.000526 0.000303 0.000683 0.000483 0.000760 0.000301 0.000769 0.000834
Endosome 0.030660 0.097770 0.111556 0.068658 0.069172 0.083241 0.086989 0.034859 0.068185 0.088983 0.088733 0.051538
Golgi 0.076705 0.083077 0.072341 0.066985 0.062559 0.073892 0.038970 0.044663 0.062921 0.077522 0.041339 0.055678
Lipid Particles 0.022619 0.035701 0.076097 0.004719 0.020830 0.030091 0.006419 0.003817 0.020875 0.032308 0.011367 0.004263
Mitochondria 0.377118* 0.256044* 0.103810* 0.290039* 0.287676* 0.227227* 0.183139* 0.470514* 0.289966* 0.238615* 0.177506* 0.381455*
Mitotic Spindle 0.037028 0.013453 0.106235* 0.106877* 0.016351 0.009481 0.102529* 0.034173 0.016881 0.011051 0.102792* 0.070050
None 0.001456 0.000655 0.000391 0.000509 0.001232 0.000697 0.000553 0.001210 0.001238 0.000680 0.000542 0.000864
Nuclear Periphery 0.002664 0.000114 0.002138 0.000598 0.000099 0.000061 0.000417 0.000144 0.000165 0.000082 0.000539 0.000368
Nuclear Periphery Foci 0.027768 0.001580 0.010636 0.001768 0.004260 0.001185 0.002070 0.000578 0.004862 0.001341 0.002678 0.001165
Nucleolus 0.006457 0.000463 0.000878 0.001145 0.001629 0.001342 0.002391 0.001970 0.001753 0.000994 0.002284 0.001563
Nucleus 0.072722 0.000814 0.005619 0.003284 0.001026 0.000980 0.002615 0.001980 0.002862 0.000914 0.002828 0.002623
Peroxisomes 0.130345* 0.379386* 0.161463* 0.087481 0.286355* 0.457589* 0.184553* 0.125688* 0.282360* 0.426685* 0.182913* 0.106834*
Vacuole 0.034858 0.004259 0.020655 0.030942 0.005248 0.002820 0.025884 0.010673 0.006006 0.003389 0.025513 0.020675
Vacuole Periphery 0.018842 0.003271 0.006114 0.018441 0.003676 0.001576 0.008605 0.004665 0.004064 0.002245 0.008428 0.011463

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.81 -0.35 1.50 -1.73 2.70 -1.53 -2.27 -6.60 -5.80 -4.82 -1.88 -2.94 -7.10 -5.91 -3.47
Bud Neck -1.36 -3.79 -9.67 -8.69 0.56 3.92 -10.77 -2.23 -5.92 8.36 3.97 -11.03 -5.76 -10.87 6.93
Bud Site 1.18 -1.12 -7.88 -20.90 -8.24 8.92 -15.17 -8.45 -14.90 5.21 9.97 -14.85 -15.34 -25.33 0.73
Cell Periphery -0.06 -1.25 -5.05 -5.76 -0.10 -0.22 1.65 -0.20 0.12 -2.07 0.56 1.57 0.28 -0.45 -2.15
Cytoplasm 1.51 0.94 -2.47 -10.84 -6.47 6.52 -8.11 -2.50 -8.02 5.34 7.29 -7.70 -6.30 -13.42 2.02
Cytoplasmic Foci -0.11 -5.12 -3.09 -9.30 3.95 15.49 -3.24 2.38 -10.97 5.33 14.93 -3.94 2.17 -14.79 6.45
Eisosomes 2.56 -0.06 2.76 0.84 4.14 2.97 3.29 0.72 -4.49 -4.55 3.09 3.02 2.09 -2.80 -2.18
Endoplasmic Reticulum 2.89 2.22 2.60 -4.72 0.85 3.41 -1.18 0.51 -1.82 1.40 4.33 -0.16 -0.52 -5.02 -0.28
Endosome -8.21 -6.06 -4.76 6.08 3.81 -3.30 -3.83 9.94 13.14 13.67 -5.49 -4.61 5.36 12.51 10.48
Golgi -0.37 0.28 0.63 4.02 0.73 -3.44 8.87 5.61 8.59 -1.96 -4.97 8.18 2.94 8.20 -5.07
Lipid Particles -1.33 -3.71 2.05 9.87 6.59 -3.18 7.63 9.23 11.18 2.66 -4.51 4.79 9.37 14.86 5.85
Mitochondria 2.17 4.88 1.78 -1.58 -9.50 5.15 9.99 -12.91 -17.75 -22.51* 4.83 11.01 -7.44 -13.93 -20.57
Mitotic Spindle 1.54 -2.99 -4.19 -18.02 -0.14 4.27 -19.13 -6.36 -9.24 13.52 3.82 -19.63 -16.98 -20.00 6.11
None 1.70 2.42 2.16 0.32 -0.98 1.66 2.35 0.05 -0.84 -1.11 1.87 2.49 0.90 -0.64 -1.11
Nuclear Periphery 2.15 0.43 1.72 -4.06 2.43 2.11 -4.68 -2.47 -6.37 4.04 2.23 -4.52 -3.11 -4.87 1.69
Nuclear Periphery Foci 1.56 0.97 1.53 -0.84 1.94 3.92 2.63 4.89 2.60 4.40 4.06 2.28 4.15 0.25 2.98
Nucleolus 2.50 2.29 2.18 -4.36 -0.88 0.36 -1.53 -0.62 -0.89 0.66 1.55 -1.13 0.26 -1.55 1.57
Nucleus 2.56 2.36 2.42 -3.77 0.38 0.09 -4.39 -2.93 -2.74 1.02 2.40 -0.49 -0.74 -4.60 -0.36
Peroxisomes -7.44 -0.85 1.37 26.86* 4.42 -15.81 11.74 18.12 33.13* 7.09 -15.38 11.80 22.98 43.58* 11.49
Vacuole 2.09 0.83 0.23 -13.92 -1.95 3.74 -12.27 -4.55 -6.74 7.85 3.66 -11.95 -11.93 -15.40 2.66
Vacuole Periphery 2.67 2.18 0.18 -10.42 -7.18 4.73 -5.99 -1.42 -5.06 4.27 3.78 -5.49 -8.77 -11.89 -2.94
Standard name
Human Ortholog
Description Protein required for ubiquinone biosynthesis and respiratory growth; localizes to matrix face of mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; ubiquinone is also known as coenzyme Q; human homolog COQ9 can complement yeast coq9 null mutant
Localization
Cell Percentages mitochondrion (48%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Coq9

Coq9


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Coq9-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available