Standard name
Human Ortholog
Description Protein of unknown function; may be involved in responding to conditions of stress; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.16 0 0 0 0 0 0 0
Bud 0 0 0.08 0 0 0 0 0.07 0.05 0.06 0 0 0 0 0 0.07 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.08 0.09 0 0 0 0 0 0
Cytoplasm 0.91 0.15 0.21 0.13 0.11 0.06 0 0 0 0 0 0.85 0.79 0.66 0.22 0.23 0.3 0.71 0 0 0.36 0.34 0.38
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.09 0 0 0 0 0 0
Endosome 0 0.19 0 0 0.22 0.05 0 0 0 0 0 0 0.09 0.15 0.17 0.17 0.2 0 0.11 0.08 0.05 0.05 0.05
Golgi 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.16 0.1 0.05 0 0.05 0 0 0 0
Mitochondria 0.05 0.48 0.76 0.87 0.61 0.83 0.84 0.89 0.9 0.92 0.94 0.09 0.08 0.13 0.12 0.16 0.12 0.13 0.67 0.67 0.42 0.4 0.35
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.07 0.14 0.17 0.11 0.16 0.14 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0.06 0 0 0.07 0 0 0 0 0 0 0 0 0.08 0.11 0.08 0.15 0 0 0 0 0 0
SpindlePole 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0.1 0.09 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0 0.19 0 0 0.15 0.09 0.06 0 0.07 0 0 0 0.05 0.07 0.14 0.11 0.15 0 0 0 0.05 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 6 7 2 1 0 0 0 0 3 5 1 4 3 0 7 21 4 13 17 12 5 12 11
Bud 2 6 26 11 7 17 23 22 22 17 17 4 2 2 3 9 4 6 4 2 4 9 9
Bud Neck 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 1 6 3 3 2 7 11
Bud Site 0 0 4 1 0 1 5 2 3 6 5 0 0 0 0 1 0
Cell Periphery 2 21 5 7 11 4 2 2 5 0 5 4 3 8 20 11 15 3 3 1 0 3 3
Cytoplasm 454 50 68 37 38 22 21 5 5 4 5 280 229 240 43 30 49 395 7 13 96 126 160
Endoplasmic Reticulum 6 11 2 4 4 2 0 0 0 1 0 6 3 0 11 5 15 2 4 3 2 2 3
Endosome 3 62 4 5 73 20 21 0 8 0 1 7 25 53 32 23 32 20 46 27 12 17 21
Golgi 2 18 1 6 2 0 0 0 1 0 0 2 3 12 30 13 8 2 21 6 6 5 6
Mitochondria 27 158 247 253 205 331 442 282 409 282 454 31 23 47 23 21 19 72 296 239 110 148 145
Nucleus 0 1 2 0 3 5 4 3 2 1 1 1 0 0 4 5 5 0 0 0 1 1 1
Nuclear Periphery 2 2 3 0 4 28 8 10 6 6 14 0 0 0 0 1 0 0 1 2 0 0 1
Nucleolus 0 1 2 1 6 29 72 53 50 48 70 1 2 0 0 1 0 0 1 1 0 1 1
Peroxisomes 0 21 4 5 23 6 18 3 15 9 12 1 4 30 22 10 25 2 6 15 1 3 2
SpindlePole 3 3 16 2 12 7 15 5 13 6 6 2 2 4 20 12 13 13 4 10 2 8 10
Vac/Vac Membrane 5 61 8 3 51 34 31 14 30 12 16 5 14 27 26 15 24 11 16 7 13 16 20
Unique Cell Count 497 328 325 292 338 400 528 318 454 308 483 329 291 365 192 132 163 559 440 358 266 369 423
Labelled Cell Count 515 422 395 336 439 506 662 401 572 397 607 348 313 423 241 180 214 559 440 358 266 369 423


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 6.3 4.3 4.9 6.3 6.8 12.4 16.0 19.0 23.1 26.1 4.9 5.8 6.1 7.0 6.9 6.7 6.4 6.5 6.5
Std Deviation (1e-4) 0.5 1.3 1.4 2.5 2.5 3.7 11.0 16.7 19.7 22.6 24.9 1.0 2.6 3.3 1.8 1.7 2.1 8.3 10.0 12.6
Intensity Change (Log2) 0.21 0.56 0.67 1.53 1.9 2.16 2.43 2.61 0.2 0.44 0.52 0.71 0.7 0.65 0.58 0.6 0.6


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 6.8 0
Bud -2.2 -3.5 -2.1 -2.2 -0.5 -1.8 -1.2 -2.8 -4.1 -4.4 -5.0 -3.1 -0.4 -2.4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.8 1.4 0 0 0 0 0 0 0 0 0.6 4.5 0 4.0
Cytoplasm -2.7 -3.4 -6.3 -7.9 -7.7 -9.4 -7.8 -9.7 16.4 14.3 11.8 0.4 0.4 2.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 4.9
Endosome 0 8.2 2.8 2.3 0 0.6 0 0 0.9 4.3 6.3 6.7 6.7 7.3
Golgi 0 0 0 0 0 0 0 0 0 0 2.9 7.1 0 0
Mitochondria 3.4 -4.2 2.2 2.8 4.2 5.3 5.3 7.4 -17.2 -17.0 -16.7 -14.1 -11.8 -13.5
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 4.0 0 2.0 0 0 1.9 0 0 0 0 0 0
Nucleolus 0 0 4.4 6.6 7.3 5.7 7.0 6.8 0 0 0 0 0 0
Peroxisomes 0 3.6 0 1.9 0 1.8 1.5 1.3 0 0 4.2 5.1 0 6.2
SpindlePole -3.1 -0.9 -2.4 -1.6 -2.4 -1.5 -2.0 -3.2 -3.4 -3.1 -3.0 2.4 1.7 1.3
Vacuole -1.3 5.7 3.5 2.3 1.4 2.6 1.0 0.7 -0.9 1.6 2.9 4.9 3.9 5.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.0308 8.3909 6.881 5.8423 5.2328 6.5428 6.7215 7.8066 7.7396 7.2044 6.9348 7.1617 8.8091 9.2606 8.1696 8.7014 7.6472 9.2586
Actin 0.0493 0.009 0.0171 0.0027 0.0042 0.0127 0.0164 0.0187 0.0149 0.0515 0.0201 0.0033 0.0224 0.008 0.0096 0.0172 0.0283 0.0052
Bud 0.0011 0.0022 0.0004 0.0002 0.0012 0.0004 0.0018 0.0005 0.0033 0.0002 0.0007 0.0002 0.0003 0.0008 0.0004 0.0007 0.0008 0.0001
Bud Neck 0.0005 0.0003 0.0005 0.0001 0.0004 0.0004 0.0019 0.0002 0.0003 0.0002 0.0001 0.0003 0.0004 0.0002 0.0028 0.0003 0.0014 0.0002
Bud Periphery 0.0025 0.0017 0.0009 0.0003 0.0057 0.0009 0.0038 0.0007 0.0037 0.0003 0.0014 0.0004 0.0006 0.0012 0.0006 0.0018 0.0022 0.0003
Bud Site 0.0018 0.0059 0.0027 0.0003 0.0007 0.0006 0.0115 0.0015 0.0054 0.0003 0.0006 0.0006 0.0011 0.0064 0.0033 0.0013 0.0011 0.0002
Cell Periphery 0.0006 0.0006 0.0004 0.0001 0.0002 0.0003 0.0013 0.0003 0.0003 0.0001 0.0002 0.0001 0.0002 0.0002 0.0002 0.0003 0.0003 0.0001
Cytoplasm 0.0055 0.0012 0.0006 0.0002 0.0008 0.0006 0.0014 0.0001 0.0003 0.0001 0.0001 0.0002 0.001 0.0022 0.002 0.0001 0.0006 0.0002
Cytoplasmic Foci 0.0204 0.0098 0.0083 0.0125 0.0194 0.0079 0.0148 0.0029 0.0086 0.0049 0.0029 0.0059 0.014 0.0083 0.0078 0.0017 0.0065 0.0038
Eisosomes 0.0011 0.0004 0.0005 0.0002 0.0002 0.0006 0.0004 0.0009 0.0005 0.0003 0.0002 0.0002 0.0003 0.0003 0.0004 0.0006 0.0006 0.0002
Endoplasmic Reticulum 0.0037 0.0003 0.0023 0.0002 0.0006 0.0031 0.0005 0.0001 0.0002 0.0001 0.0001 0.0002 0.0013 0.0004 0.0007 0 0.0018 0.0002
Endosome 0.047 0.032 0.0339 0.0149 0.0606 0.0309 0.0265 0.0065 0.0098 0.0103 0.0122 0.0106 0.0326 0.0254 0.0265 0.0027 0.044 0.0188
Golgi 0.061 0.0528 0.047 0.0394 0.0537 0.0772 0.0262 0.03 0.0397 0.0515 0.014 0.0422 0.0459 0.0514 0.0298 0.0047 0.0618 0.0445
Lipid Particles 0.0494 0.0062 0.0105 0.0101 0.0191 0.009 0.027 0.001 0.0046 0.0042 0.0018 0.0104 0.016 0.0065 0.005 0.0003 0.0265 0.0032
Mitochondria 0.6998 0.8592 0.8465 0.9111 0.8163 0.8303 0.836 0.9253 0.8922 0.8693 0.916 0.9139 0.834 0.8647 0.8879 0.9625 0.7963 0.9087
None 0.0034 0.0004 0.0004 0.0001 0.0004 0.0004 0.0018 0 0.0001 0.0001 0.0001 0.0001 0.0011 0.0045 0.001 0.0001 0.0008 0.0001
Nuclear Periphery 0.0065 0.0001 0.0019 0.0001 0.0008 0.0032 0.0011 0 0.0002 0.0001 0 0.0001 0.0037 0.0005 0.0044 0 0.0074 0.0012
Nucleolus 0.0016 0.0004 0.0001 0.0001 0.0003 0.0005 0.0015 0.0001 0.0007 0 0.0002 0.0008 0.0004 0.0002 0.0003 0.0001 0.0012 0.0001
Nucleus 0.0035 0.0002 0.0003 0.0001 0.0002 0.0015 0.0008 0.0001 0.0003 0 0.0001 0.0002 0.0007 0.0002 0.0005 0.0001 0.0021 0.0002
Peroxisomes 0.0215 0.0079 0.0163 0.0052 0.0072 0.014 0.0115 0.0087 0.0119 0.0052 0.02 0.0062 0.0147 0.0112 0.0116 0.0046 0.0047 0.008
Punctate Nuclear 0.0043 0.0001 0.0004 0.0003 0.0022 0.0005 0.0024 0 0.0002 0.0001 0 0.002 0.0026 0.0001 0.0018 0 0.0019 0.0004
Vacuole 0.0067 0.0043 0.0039 0.0007 0.0025 0.0019 0.0079 0.0012 0.0009 0.0003 0.0054 0.0009 0.0027 0.0027 0.0016 0.0005 0.0036 0.0012
Vacuole Periphery 0.009 0.0048 0.0051 0.0012 0.0034 0.0034 0.0035 0.0013 0.0023 0.001 0.0039 0.0012 0.0041 0.0045 0.0019 0.0004 0.0061 0.0033

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression
Translational Efficiency

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
124 1744 168 783 1677 1635 124 798 1801 3379 292 1581

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 631.31 793.56 945.36 889.45 741.64 777.20 1830.41 895.19 734.04 785.64 1321.20 892.35
Standard Deviation 63.83 137.93 116.89 161.40 136.70 178.39 820.74 215.34 135.87 159.01 696.63 190.57
Intensity Change Log 2 0.329991 0.582515 0.494565 0.067567 1.303376 0.271475 0.194184 1.015609 0.378354

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000288 0.002712 0.002896 0.005296 0.002850 0.001292 0.075244 0.014347 0.002674 0.002025 0.033619 0.009864
Bud Neck 0.045080 0.007510 0.012725 0.025107 0.006682 0.021022 0.004547 0.022549 0.009326 0.014048 0.009252 0.023816
Bud Site 0.016604 0.030386 0.024301 0.106216* 0.027000 0.026696 0.036073 0.129970* 0.026284 0.028600 0.029300 0.118206*
Cell Periphery 0.000277 0.000483 0.000402 0.000288 0.001144 0.000369 0.000723 0.000330 0.001084 0.000428 0.000539 0.000309
Cytoplasm 0.164928* 0.024061 0.123454* 0.189054* 0.014102 0.047825 0.007916 0.184868* 0.024487 0.035560 0.074390 0.186941*
Cytoplasmic Foci 0.356015* 0.068918 0.194909* 0.113370 0.053734 0.175159 0.061883 0.124323 0.074546 0.120325 0.138419 0.118898
Eisosomes 0.000296 0.000096 0.000255 0.000094 0.000150 0.000171 0.001781 0.000132 0.000161 0.000132 0.000903 0.000113
Endoplasmic Reticulum 0.001678 0.000541 0.011430 0.002571 0.000747 0.000816 0.001630 0.001865 0.000811 0.000674 0.007269 0.002215
Endosome 0.045722 0.081282 0.089591 0.059878 0.070271 0.112210 0.040773 0.050893 0.068581 0.096247 0.068860 0.055343
Golgi 0.026854 0.126738* 0.022391 0.032606 0.088648 0.129450* 0.230374* 0.041468 0.084394 0.128050* 0.110713* 0.037079
Lipid Particles 0.048136 0.003520 0.024546 0.002405 0.004702 0.007664 0.004784 0.002696 0.007692 0.005525 0.016154 0.002552
Mitochondria 0.124409* 0.548250* 0.019716 0.031114 0.639947* 0.342020* 0.462999* 0.052724 0.604452* 0.448461* 0.207959* 0.042022
Mitotic Spindle 0.001736 0.021363 0.052397 0.116463* 0.009112 0.020701 0.021310 0.096400 0.008605 0.021042 0.039196 0.106336*
None 0.001836 0.000703 0.001429 0.002117 0.000583 0.001238 0.001393 0.002885 0.000670 0.000962 0.001414 0.002505
Nuclear Periphery 0.002416 0.000078 0.002860 0.001835 0.000136 0.000203 0.000364 0.002011 0.000293 0.000139 0.001800 0.001924
Nuclear Periphery Foci 0.000535 0.000429 0.006765 0.002610 0.000460 0.000311 0.000289 0.002299 0.000465 0.000372 0.004015 0.002453
Nucleolus 0.004324 0.000502 0.006517 0.001598 0.000421 0.001494 0.000185 0.001436 0.000690 0.000982 0.003828 0.001517
Nucleus 0.059869 0.001838 0.184751* 0.039810 0.000903 0.005773 0.000275 0.030978 0.004963 0.003742 0.106412 0.035352
Peroxisomes 0.059398 0.055139 0.050629 0.044325 0.053503 0.059869 0.017751 0.067840 0.053909 0.057428 0.036667 0.056194
Vacuole 0.026957 0.015230 0.157802 0.207518* 0.010747 0.031150 0.017409 0.154464 0.011863 0.022933 0.098183 0.180739
Vacuole Periphery 0.012641 0.010221 0.010234 0.015723 0.014155 0.014567 0.012296 0.015523 0.014051 0.012324 0.011110 0.015622

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.67 -6.46 -5.90 -1.73 -1.48 3.12 -4.48 -4.76 -5.77 3.92 1.36 -4.31 -4.90 -5.94 3.57
Bud Neck 4.81 4.16 3.08 -7.27 -3.76 -8.27 1.40 -8.17 -0.03 -8.12 -3.81 0.23 -8.20 -4.71 -7.54
Bud Site -2.55 -1.05 -8.56 -8.53 -8.77 0.12 -1.08 -12.80 -13.08 -6.86 -0.93 -0.52 -15.10 -15.39 -11.13
Cell Periphery -2.68 -3.09 1.25 3.21 3.59 2.93 1.37 3.33 1.81 3.25 2.65 2.13 3.46 3.67 4.47
Cytoplasm 7.74 1.84 -2.62 -21.29 -6.16 -10.50 0.54 -22.02 -17.44 -19.83 -4.21 -6.32 -29.02 -27.40 -13.57
Cytoplasmic Foci 13.47 6.70 12.35 -4.22 7.62 -23.77 -0.79 -10.27 9.91 -4.15 -10.81 -6.27 -5.47 4.91 3.72
Eisosomes 7.00 0.70 7.28 1.07 9.99 -0.72 -3.74 1.43 1.90 3.82 1.49 -3.95 3.30 2.04 4.26
Endoplasmic Reticulum 1.77 -4.84 -1.52 -8.22 4.53 -0.25 -2.42 -4.69 -3.82 -0.93 0.72 -5.51 -6.91 -8.22 4.27
Endosome -4.29 -3.39 0.96 10.27 5.25 -8.83 4.45 7.48 15.98 -0.03 -7.46 0.51 8.29 18.60 4.44
Golgi -12.48 0.88 0.99 22.41 0.08 -7.10 -5.88 12.12 18.35 8.36 -9.55 -1.91 14.92 28.59 6.94
Lipid Particles 4.96 2.39 5.07 1.44 7.96 -2.58 0.09 2.63 5.90 1.56 2.10 -4.24 5.21 5.55 7.60
Mitochondria -19.99* 5.26 5.24 56.72* -0.26 24.94* 5.06 61.56* 32.50* 11.98 14.46 18.56 62.47* 61.22* 8.87
Mitotic Spindle -10.66 -4.39 -11.88 -8.97 -3.04 -5.91 -1.90 -11.12 -9.15 -6.44 -8.25 -4.20 -15.49 -12.79 -5.69
None 2.85 0.72 -0.09 -2.24 -0.68 -1.99 -2.97 -2.37 -1.38 -1.32 -1.57 -3.63 -3.16 -2.40 -1.44
Nuclear Periphery 1.69 -0.32 0.45 -4.94 1.53 -1.06 -2.96 -2.08 -1.99 -1.78 1.37 -3.89 -3.31 -3.74 0.05
Nuclear Periphery Foci 0.38 -4.63 -3.30 -3.45 3.50 0.76 0.89 -2.34 -2.62 -2.65 0.47 -4.42 -3.75 -4.14 2.54
Nucleolus 2.51 -1.29 1.84 -2.98 3.74 -3.48 1.86 -4.29 0.26 -5.27 -1.31 -3.96 -3.14 -1.94 3.12
Nucleus 6.22 -6.12 0.12 -13.98 6.72 -6.83 0.41 -12.46 -10.79 -12.41 1.38 -8.50 -16.73 -17.62 4.68
Peroxisomes 0.31 0.84 2.29 5.07 2.03 -1.39 5.58 -0.29 0.86 -5.30 -0.88 3.32 2.37 3.86 -1.61
Vacuole 2.51 -10.26 -24.37 -28.36 -8.81 -11.33 -1.23 -23.52 -20.94 -17.31 -8.44 -10.35 -36.44 -34.71 -14.18
Vacuole Periphery 0.35 0.54 0.49 0.52 -0.14 -0.28 0.79 1.38 1.58 0.29 1.57 2.22 2.39 1.45 -0.02
Standard name
Human Ortholog
Description Protein of unknown function; may be involved in responding to conditions of stress; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages mitochondrion (90%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Fmp16

Fmp16


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fmp16-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available