Standard name
Human Ortholog
Description Cytoplasmic protein that regulates protein phosphatase 1 Glc7p; protein overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.05 0.07 0.11 0.13 0.14
Bud 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0.05
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.17 0.2 0.18 0.09 0.12 0.06 0.06 0.06 0.09 0.07 0.08 0.12 0.12 0.21 0.21 0.25 0.31 0.31 0.15 0.06 0.13 0.34 0.36 0.2
Cytoplasm 0.96 0.95 0.99 0.97 0.96 0.93 0.92 0.94 0.85 0.79 0.78 0.7 0.99 0.99 0.97 0.86 0.87 0.88 0.57 0.73 0.61 0.36 0.28 0.41
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.05 0.08 0 0 0.06 0.07 0.07
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0.08 0.08 0.27 0.27 0.42 0.35 0 0 0 0 0 0 0 0 0.1 0.05 0.07 0.07
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 4 5 1 1 3 2 3 6 3 4 3 6 0 1 4 5 5 1 12 13 15 11 30 29
Bud 1 2 5 0 1 3 3 4 15 5 5 5 6 1 5 0 0 0 0 0 0 0 1 0
Bud Neck 0 0 1 1 3 2 1 1 3 0 0 0 0 0 0 0 0 0 9 10 7 4 7 10
Bud Site 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 26 52 38 16 30 15 15 19 18 13 14 19 28 59 75 66 60 53 24 17 30 35 80 41
Cytoplasm 147 243 204 177 237 230 243 303 173 154 134 112 237 275 346 225 171 150 95 197 138 37 63 88
Endoplasmic Reticulum 2 4 0 1 1 5 1 1 3 0 1 2 1 2 2 16 6 9 14 7 3 6 15 14
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 1 0 2 1 0 2 2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 4 0 1 0 0 0 2
Mitochondria 1 1 0 1 3 11 22 26 54 52 71 57 0 0 1 6 3 1 6 7 22 5 16 13
Nucleus 0 1 0 0 1 1 2 2 1 2 3 2 0 0 0 3 2 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 2 1 0 0 0 1 1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 1 0 0 0 2 0 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 1 0 1 2 0 0 1 0 0 1 1 11 4 8 0 12 3 2 4 2
Unique Cell Count 153 256 206 182 248 248 265 321 203 195 171 161 239 277 357 261 196 171 167 272 227 104 227 214
Labelled Cell Count 182 308 249 197 282 270 292 365 270 233 234 205 272 339 436 338 252 227 167 272 227 104 227 214


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 6.1 5.4 5.2 6.0 4.5 4.9 5.0 4.1 4.0 3.9 4.3 5.3 5.5 5.8 8.9 8.8 9.0 5.3 5.5 6.0
Std Deviation (1e-4) 0.6 0.8 0.8 1.2 1.7 0.9 1.3 1.1 1.0 0.9 1.3 0.9 0.9 1.0 1.0 1.5 1.4 1.5 1.2 1.5 1.6
Intensity Change (Log2) – – – -0.04 0.17 -0.26 -0.13 -0.11 -0.38 -0.43 -0.44 -0.31 -0.01 0.04 0.12 0.74 0.71 0.74 -0.0 0.04 0.17

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0.1 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -2.7 -1.9 0 -4.4 -4.5 0 0 0 0 -2.0 0.8 0.7 1.8 2.8 2.8
Cytoplasm -1.3 -2.2 -3.3 -3.6 -2.7 -5.2 -6.5 -6.6 -8.1 0.1 0.3 -1.6 -5.0 -4.7 -4.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 3.6 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 4.2 4.2 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.308 1.1629 0.8148 0.6397 0.9649 1.0273 0.7627 1.2838 1.0232 0.7847 1.0012 0.8079 0.8191 1.1538 0.6648 0.5795 0.3675 0.7512
Actin 0.0465 0.0218 0.0258 0.0204 0.0233 0.0332 0.0632 0.0365 0.0229 0.0743 0.0378 0.0441 0.0561 0.025 0.0208 0.0014 0.0834 0.0182
Bud 0.0005 0.0004 0.0012 0.0014 0.0124 0.0004 0.0015 0.0006 0.001 0.0009 0.0006 0.0011 0.0009 0.0007 0.0012 0.001 0.0014 0.0011
Bud Neck 0.0021 0.0035 0.0029 0.0087 0.008 0.0137 0.0072 0.0023 0.0033 0.0013 0.0023 0.0111 0.0043 0.002 0.0029 0.002 0.008 0.0071
Bud Periphery 0.0014 0.0011 0.0065 0.0047 0.043 0.003 0.0035 0.0013 0.002 0.0029 0.002 0.005 0.0037 0.0015 0.0035 0.0016 0.0043 0.0069
Bud Site 0.0041 0.0373 0.0148 0.0036 0.0094 0.001 0.0142 0.052 0.0197 0.0018 0.0009 0.0011 0.008 0.0431 0.0113 0.0049 0.011 0.0011
Cell Periphery 0.0313 0.0257 0.0196 0.0149 0.0041 0.0209 0.0309 0.019 0.0098 0.0031 0.0022 0.0239 0.0232 0.022 0.0151 0.0017 0.013 0.0207
Cytoplasm 0.5263 0.6275 0.6568 0.6917 0.6686 0.6992 0.6174 0.747 0.7994 0.805 0.7814 0.7993 0.6649 0.6804 0.7146 0.746 0.8017 0.8071
Cytoplasmic Foci 0.0197 0.0059 0.0102 0.008 0.0093 0.0092 0.0428 0.0053 0.0144 0.0081 0.0536 0.0103 0.0198 0.0052 0.0053 0.0118 0.0215 0.0066
Eisosomes 0.002 0.002 0.0015 0.0006 0.0006 0.0013 0.0036 0.001 0.0003 0.0006 0.0005 0.0007 0.0017 0.0009 0.0009 0.0006 0.0011 0.0006
Endoplasmic Reticulum 0.0144 0.0053 0.0051 0.011 0.003 0.0069 0.0076 0.0019 0.0025 0.0058 0.0029 0.0048 0.0046 0.0021 0.004 0.0034 0.0024 0.0034
Endosome 0.023 0.0025 0.0144 0.0177 0.0273 0.0027 0.0289 0.0008 0.0072 0.0104 0.0378 0.0024 0.0153 0.0004 0.0012 0.0033 0.0026 0.0021
Golgi 0.006 0.0049 0.0058 0.0147 0.0311 0.0021 0.0144 0.002 0.0051 0.0152 0.0097 0.0042 0.0057 0.0011 0.0021 0.0006 0.0052 0.0021
Lipid Particles 0.0167 0.0008 0.0036 0.0031 0.0036 0.002 0.0289 0.0004 0.0045 0.0132 0.0073 0.0018 0.0078 0.0006 0.0046 0.0004 0.0007 0.0027
Mitochondria 0.0058 0.0005 0.0063 0.1008 0.0159 0.0088 0.0042 0.0001 0.0008 0.002 0.0009 0.0065 0.0029 0.0002 0.0007 0.0002 0.0003 0.0023
None 0.2586 0.2586 0.2133 0.0894 0.1286 0.1897 0.0959 0.1282 0.0968 0.0505 0.0258 0.0801 0.1557 0.2133 0.2 0.2159 0.0409 0.1149
Nuclear Periphery 0.0089 0.0002 0.0016 0.0011 0.001 0.0025 0.0091 0.0001 0.0006 0.0015 0.0117 0.0002 0.0023 0.0001 0.0003 0.0004 0.0001 0.0006
Nucleolus 0.0008 0.0002 0.0004 0.0003 0.0007 0.0002 0.0006 0.0001 0.0002 0.0001 0.0008 0.0001 0.0009 0.0001 0.0002 0.0002 0.0001 0.0001
Nucleus 0.0168 0.0004 0.0008 0.0009 0.0014 0.0007 0.003 0.0003 0.0008 0.0005 0.0044 0.0003 0.002 0.0003 0.0005 0.001 0.0002 0.0004
Peroxisomes 0.0081 0.0002 0.002 0.0015 0.0015 0.0005 0.0168 0.0002 0.006 0.001 0.0069 0.002 0.0108 0.0002 0.0088 0.0001 0.0014 0.0004
Punctate Nuclear 0.0027 0.0002 0.0039 0.0004 0.0008 0.0004 0.0025 0.0001 0.0008 0.0006 0.0079 0.0002 0.0068 0.0001 0.0007 0.0005 0.0002 0.0003
Vacuole 0.0035 0.001 0.0029 0.0037 0.005 0.001 0.0028 0.0006 0.0019 0.001 0.0019 0.0008 0.0019 0.0007 0.0011 0.0028 0.0007 0.0012
Vacuole Periphery 0.0008 0.0001 0.0005 0.0015 0.0014 0.0005 0.001 0 0.0002 0.0004 0.0008 0.0001 0.0006 0 0.0001 0.0002 0.0001 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.5581 11.6654 7.0532 11.2896 7.833 6.7626 12.2317 13.7102 12.3894 13.0275
Translational Efficiency 0.8702 0.4785 0.6818 0.5965 0.7599 0.7284 0.6653 0.5164 0.4824 0.4704

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
535 1123 1592 1227 1302 1448 114 1800 1837 2571 1706 3027

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 668.40 777.49 948.64 971.05 729.44 823.13 1046.54 944.31 711.66 803.19 955.18 955.15
Standard Deviation 74.94 132.35 109.37 115.94 84.04 104.72 108.77 128.80 86.08 119.75 112.03 124.44
Intensity Change Log 2 — 0.218112 0.505149 0.538834 — 0.174331 0.520766 0.372471 — 0.195432 0.513320 0.454416

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002721 0.012948 0.016254 0.164679 0.004126 0.011738 0.018360 0.039272 0.003717 0.012266 0.016395 0.090106
Bud Neck 0.028896 0.044959 0.008586 0.011952 0.035428 0.056508 0.005322 0.011493 0.033525 0.051463 0.008368 0.011679
Bud Site 0.008616 0.043498 0.048395 0.114575 0.013328 0.042884 0.024476 0.055638 0.011956 0.043152 0.046797 0.079528
Cell Periphery 0.001845 0.005555 0.002211 0.015150 0.003999 0.005062 0.004885 0.002974 0.003372 0.005277 0.002389 0.007909
Cytoplasm 0.419783 0.440386 0.577937 0.376478 0.531008 0.544000 0.306367 0.503331 0.498615 0.498742 0.559790 0.451911
Cytoplasmic Foci 0.299240 0.226283 0.088134 0.041219 0.223133 0.164045 0.187815 0.084732 0.245298 0.191230 0.094795 0.067094
Eisosomes 0.009284 0.014173 0.001110 0.019775 0.013954 0.016911 0.003069 0.006273 0.012594 0.015715 0.001241 0.011746
Endoplasmic Reticulum 0.002397 0.003964 0.011351 0.006230 0.003007 0.001914 0.008195 0.002900 0.002829 0.002809 0.011140 0.004250
Endosome 0.035516 0.033828 0.004144 0.003018 0.017261 0.016010 0.024152 0.010667 0.022577 0.023793 0.005481 0.007567
Golgi 0.017990 0.036256 0.001348 0.002526 0.026610 0.023649 0.001534 0.003318 0.024099 0.029155 0.001361 0.002997
Lipid Particles 0.041973 0.026409 0.004514 0.003664 0.020718 0.009006 0.016392 0.009408 0.026908 0.016607 0.005308 0.007080
Mitochondria 0.004790 0.007640 0.000248 0.000531 0.006205 0.006004 0.000141 0.000716 0.005793 0.006718 0.000241 0.000641
Mitotic Spindle 0.000070 0.001353 0.002140 0.004271 0.000188 0.003489 0.000196 0.010344 0.000153 0.002556 0.002010 0.007882
None 0.002059 0.001532 0.001086 0.000974 0.001489 0.000930 0.000193 0.000717 0.001655 0.001193 0.001026 0.000821
Nuclear Periphery 0.000622 0.000324 0.000266 0.000090 0.000101 0.000054 0.000433 0.000221 0.000253 0.000172 0.000277 0.000168
Nuclear Periphery Foci 0.000523 0.001022 0.004297 0.001359 0.000351 0.000409 0.009588 0.001775 0.000401 0.000677 0.004651 0.001606
Nucleolus 0.000480 0.000407 0.000087 0.000039 0.000250 0.000502 0.000308 0.000299 0.000317 0.000460 0.000102 0.000194
Nucleus 0.034587 0.020592 0.115729 0.030795 0.040450 0.023072 0.056929 0.038817 0.038742 0.021989 0.111800 0.035565
Peroxisomes 0.016394 0.018492 0.001680 0.005462 0.011884 0.014032 0.006681 0.006795 0.013198 0.015980 0.002014 0.006255
Vacuole 0.071080 0.058284 0.110351 0.196036 0.045348 0.058026 0.324703 0.209669 0.052842 0.058139 0.124674 0.204143
Vacuole Periphery 0.001136 0.002096 0.000133 0.001176 0.001163 0.001757 0.000260 0.000641 0.001155 0.001905 0.000141 0.000858

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.29 -6.87 -19.10 -17.36 -16.85 -6.90 -2.09 -10.77 -7.48 -2.21 -9.81 -6.83 -21.07 -18.06 -15.87
Bud Neck -4.61 8.45 7.62 13.17 -2.31 -6.81 15.89 13.20 17.89 -5.74 -7.73 16.43 15.31 22.15 -3.04
Bud Site -15.07 -14.51 -19.98 -11.34 -10.64 -12.73 -2.86 -13.65 -2.07 -6.18 -18.79 -13.77 -23.40 -9.40 -7.82
Cell Periphery -5.37 -0.59 -8.00 -4.70 -8.03 -1.97 -0.35 3.43 5.09 1.68 -4.33 3.72 -5.05 -1.68 -7.41
Cytoplasm -1.67 -11.39 3.45 6.00 17.58 -1.51 11.28 4.49 5.92 -9.35 -0.00 -4.60 7.36 7.73 11.22
Cytoplasmic Foci 7.33 24.58 30.12 31.12 13.20 9.64 3.39 26.71 17.00 7.65 10.12 31.29 39.84 32.63 8.22
Eisosomes -2.22 4.80 -2.75 -0.68 -9.56 -1.74 7.47 6.70 8.27 -2.04 -2.34 12.02 2.68 5.32 -11.10
Endoplasmic Reticulum -2.19 -9.98 -4.37 -1.93 6.28 2.13 -2.57 0.76 -1.29 2.78 0.04 -10.37 -2.09 -2.11 9.16
Endosome 0.45 11.24 11.68 13.28 3.24 1.03 -1.89 6.09 5.73 4.34 -0.80 15.41 13.22 13.84 -2.02
Golgi -7.75 10.75 9.70 18.42 -1.36 1.80 20.41 18.04 16.73 -2.19 -3.61 23.41 20.68 24.67 -2.91
Lipid Particles 3.50 10.23 10.57 9.37 3.30 8.68 1.58 8.03 0.64 2.77 5.72 15.34 13.76 8.04 -1.41
Mitochondria -1.95 4.39 4.17 6.87 -1.23 0.13 5.11 4.66 4.83 -2.39 -0.78 6.22 5.83 7.94 -2.34
Mitotic Spindle -1.60 -2.72 -3.33 -1.70 -0.91 -2.86 -0.03 -5.38 -2.76 -5.38 -3.25 -2.62 -6.24 -3.29 -3.48
None 0.54 1.28 1.36 1.02 0.45 1.53 4.64 2.55 0.92 -3.26 1.11 2.12 2.50 1.36 0.94
Nuclear Periphery 1.09 1.24 2.05 2.15 9.43 4.73 -5.94 -4.63 -6.51 3.64 0.92 -0.90 0.99 -0.11 6.31
Nuclear Periphery Foci -1.92 -16.16 -8.62 -1.54 11.78 -0.82 -8.31 -7.18 -6.08 6.98 -2.29 -18.46 -9.93 -5.38 12.03
Nucleolus 0.82 6.19 6.92 6.43 7.14 -1.23 -0.66 -0.22 0.93 0.13 -1.22 6.86 1.35 1.82 -0.90
Nucleus 6.63 -22.50 1.10 -6.52 24.28 9.35 -1.78 0.71 -8.53 1.96 11.79 -22.62 1.62 -10.79 23.67
Peroxisomes -1.00 8.87 6.75 9.86 -7.18 -1.72 2.05 5.52 6.66 0.12 -2.57 14.53 8.78 11.36 -6.88
Vacuole 2.67 -10.94 -22.05 -25.08 -14.36 -4.52 -13.68 -33.98 -31.13 4.87 -2.24 -20.41 -41.01 -39.93 -16.14
Vacuole Periphery -4.02 9.07 0.50 2.45 -1.81 -1.12 7.11 2.42 2.15 -1.26 -2.35 11.05 1.93 3.21 -2.49
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cytoplasmic protein that regulates protein phosphatase 1 Glc7p; protein overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate
Localization
Cell Percentages cytoplasm (32%), ER (3%), mixed (50%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Gip4

Gip4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gip4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available