Standard name
Human Ortholog
Description Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.06 0 0.17 0.17 0.3 0.15 0.13 0.13 0.08 0.11 0.08 0.08 0.27 0.34 0.42 0.1 0.08 0.08 0 0 0.05 0.13 0.15 0.18
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.09 0 0.05 0.05 0.08 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.21 0.3 0.08 0.23 0.14 0.52 0.63 0.59 0.67 0.74 0.81 0.8 0 0 0 0 0.06 0.07 0 0 0.05 0 0 0
Nucleus 0.66 0.66 0.65 0.59 0.48 0.48 0.47 0.51 0.48 0.43 0.42 0.44 0.62 0.52 0.48 0.81 0.83 0.83 0.52 0.67 0.45 0.49 0.39 0.32
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.2 0.23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.09 0.11 0.07 0.07 0.07
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.06 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0.08 0.09 0.1 0.13
Vac/Vac Membrane 0 0.09 0.07 0 0.07 0.06 0.06 0.05 0 0.07 0.09 0 0.05 0.1 0.09 0.07 0 0.05 0.14 0.11 0.14 0.11 0.14 0.14
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 2
Bud 1 0 0 0 1 1 2 1 3 10 2 4 0 0 0 0 0 0 4 0 2 2 6 13
Bud Neck 0 0 0 0 1 0 0 0 0 0 0 0 1 4 0 1 0 0 0 0 0 2 5 8
Bud Site 0 0 0 0 0 3 9 7 4 6 6 6 0 0 0 1 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 9 0 18 19 31 25 30 34 19 36 16 18 59 138 176 18 16 9 6 0 7 28 55 66
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 1 0 2 2 3 3 2 1 0 1 0 2 3
Endosome 15 1 5 5 8 2 0 3 0 0 0 0 11 21 10 1 2 1 6 1 5 3 7 6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 2 0 1 1 1 0 1 0
Mitochondria 35 13 8 25 15 86 146 159 155 240 161 180 0 2 2 7 11 8 6 2 6 5 15 16
Nucleus 108 29 68 65 50 80 108 138 110 139 83 99 134 210 200 145 156 98 113 55 61 111 145 118
Nuclear Periphery 3 0 0 0 0 0 1 1 2 0 0 4 0 0 0 0 0 0 0 0 0 2 1 2
Nucleolus 33 10 2 0 1 5 9 5 8 7 5 9 1 0 1 4 4 4 23 7 14 15 27 25
Peroxisomes 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 10 0 5 3 0 3 2 2 2 2 2 0 9 12 9 1 3 0 16 2 11 20 37 49
Vac/Vac Membrane 4 4 7 3 7 10 15 13 10 24 17 8 11 40 37 13 8 6 31 9 19 23 53 51
Unique Cell Count 163 44 104 110 104 166 231 271 231 326 198 225 216 404 415 179 189 118 220 83 135 225 372 376
Labelled Cell Count 219 57 113 120 114 215 322 363 313 464 292 329 227 429 439 194 205 128 220 83 135 225 372 376


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 5.3 4.8 4.4 4.8 3.9 3.7 3.6 3.5 3.4 3.2 3.2 6.1 6.1 5.8 8.8 8.4 8.8 6.1 6.5 6.4
Std Deviation (1e-4) 0.8 1.2 1.4 1.8 2.0 1.7 1.2 1.2 1.0 0.9 1.0 1.0 1.1 1.2 1.3 1.6 1.7 1.6 1.4 1.6 1.5
Intensity Change (Log2) – – – -0.12 -0.03 -0.33 -0.38 -0.41 -0.48 -0.52 -0.61 -0.58 0.32 0.32 0.26 0.85 0.79 0.86 0.32 0.41 0.39

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 2.1 -0.5 -1.0 -1.2 -2.5 -1.7 -2.4 -2.5 2.0 3.3 4.7 -1.8 -2.3 -2.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0.1 0.2 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 -1.4 -0.6 -0.3
Nucleus -0.9 -2.5 -2.8 -3.2 -2.5 -3.0 -4.0 -3.9 -3.6 -0.6 -2.4 -3.1 2.9 3.3 3.0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 -0.2 -0.1 -0.7 -0.9 0.2 0.6 0 -0.6 1.0 0.7 0.2 -0.9 -0.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.5427 0.9029 1.1816 0.5768 0.8882 0.9922 1.1727 0.7486 0.6966 1.4467 0.7671 0.918 0.1604 0.3707 0.4241 0.392 0.0828 0.1006
Actin 0.0499 0.0002 0.0039 0.0002 0.0927 0.0002 0.0698 0.002 0.0023 0.0003 0.0041 0.0236 0.0131 0.0002 0.0066 0.0262 0.0052 0.0035
Bud 0.0002 0.0001 0.0009 0.0001 0.0003 0.0003 0.0011 0.0006 0.0006 0.0002 0.0003 0.001 0.0004 0.0002 0.0002 0.0003 0.0002 0.0002
Bud Neck 0.0031 0.0005 0.0045 0.0006 0.0043 0.0042 0.0061 0.0046 0.0008 0.0006 0.0016 0.0032 0.0021 0.0007 0.0006 0.0007 0.0032 0.003
Bud Periphery 0.0003 0.0001 0.0009 0.0001 0.0005 0.0003 0.0014 0.0005 0.0007 0.0001 0.0005 0.0021 0.0006 0.0001 0.0003 0.0008 0.0004 0.0002
Bud Site 0.0022 0.0014 0.0205 0.0002 0.0013 0.0003 0.0054 0.0061 0.0022 0.0011 0.0026 0.0012 0.0012 0.0007 0.0007 0.0004 0.0006 0.0002
Cell Periphery 0.0002 0.0001 0.0004 0 0.0001 0 0.0005 0.0001 0.0001 0 0.0003 0.0001 0.0001 0 0.0001 0.0001 0.0001 0
Cytoplasm 0.0249 0.021 0.035 0.0265 0.0013 0.0382 0.0876 0.0672 0.0363 0.07 0.1334 0.1107 0.0134 0.0144 0.0152 0.0014 0.0332 0.0087
Cytoplasmic Foci 0.0109 0.0008 0.0081 0.0048 0.0017 0.0037 0.0439 0.0022 0.01 0.0288 0.0205 0.0196 0.0056 0.0006 0.0034 0.0004 0.0018 0.0022
Eisosomes 0.0008 0 0.0001 0 0.0001 0 0.0004 0 0.0001 0 0.0002 0.0001 0.0001 0 0.0002 0.0003 0 0
Endoplasmic Reticulum 0.0018 0.0007 0.0021 0.0005 0.0002 0.0007 0.0092 0.0014 0.001 0.0014 0.0027 0.0022 0.0024 0.0003 0.0013 0.0011 0.0053 0.0005
Endosome 0.0061 0.0008 0.011 0.0004 0.0009 0.0029 0.0603 0.002 0.0108 0.0066 0.0167 0.0164 0.0142 0.0004 0.0064 0.0033 0.0104 0.0018
Golgi 0.0048 0 0.0067 0 0.0019 0.0001 0.0272 0.0005 0.0062 0.0014 0.0103 0.0144 0.0035 0 0.0022 0.003 0.001 0.0006
Lipid Particles 0.0112 0.0002 0.0039 0.0002 0.0007 0.0002 0.0306 0.0003 0.0023 0.0085 0.1057 0.0313 0.0092 0 0.0036 0.0021 0.0006 0.0024
Mitochondria 0.0028 0.0002 0.0032 0.0003 0.0012 0.0003 0.03 0.0008 0.0039 0.0445 0.0154 0.0137 0.003 0.0002 0.008 0.0026 0.0008 0.0008
None 0.097 0.0362 0.0621 0.0796 0.0007 0.0534 0.0301 0.0305 0.0527 0.026 0.1473 0.0216 0.0227 0.0153 0.0515 0.0012 0.0514 0.0132
Nuclear Periphery 0.0124 0.0061 0.0115 0.0058 0.0069 0.0028 0.0441 0.0146 0.0077 0.0074 0.0112 0.0149 0.0235 0.0041 0.0167 0.0076 0.0285 0.0165
Nucleolus 0.0167 0.0179 0.0168 0.009 0.0366 0.0481 0.0109 0.0169 0.0155 0.0058 0.0089 0.0219 0.0213 0.0171 0.0181 0.0089 0.0616 0.0364
Nucleus 0.6762 0.896 0.7152 0.8342 0.7278 0.8046 0.4729 0.8084 0.7852 0.7042 0.4538 0.6557 0.8224 0.916 0.8205 0.9252 0.6857 0.8501
Peroxisomes 0.0103 0 0.0012 0 0.0016 0.0001 0.0232 0.0002 0.0089 0.0047 0.0267 0.0107 0.0036 0 0.0036 0.0003 0.0002 0.005
Punctate Nuclear 0.0669 0.0167 0.0877 0.0374 0.1177 0.0382 0.0344 0.039 0.0503 0.0873 0.0282 0.0325 0.0337 0.0291 0.0392 0.013 0.108 0.0533
Vacuole 0.001 0.001 0.0036 0.0002 0.0012 0.0013 0.0075 0.0016 0.0015 0.0006 0.0077 0.0018 0.0027 0.0004 0.0011 0.0003 0.0013 0.0006
Vacuole Periphery 0.0004 0.0001 0.0005 0.0001 0.0003 0.0001 0.0034 0.0004 0.0007 0.0003 0.0017 0.0012 0.0014 0.0001 0.0006 0.0008 0.0006 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 19.8113 9.2401 13.1417 15.4772 9.4927 26.6874 13.0407 12.3485 17.1432 20.6074
Translational Efficiency 0.8023 1.0656 0.5712 0.8538 1.2942 0.724 0.8198 0.6109 0.605 0.6561

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1913 1480 1905 1146 1999 1750 528 25 3912 3230 2433 1171

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 705.67 779.17 848.56 855.85 723.20 788.58 940.61 1012.63 714.63 784.27 868.54 859.20
Standard Deviation 78.09 120.02 109.61 142.32 83.37 98.13 127.82 151.62 81.30 108.81 119.97 144.31
Intensity Change Log 2 — 0.142944 0.266023 0.278364 — 0.124862 0.379202 0.485641 — 0.133821 0.324416 0.386990

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000109 0.000523 0.000587 0.001476 0.000489 0.000825 0.000946 0.000633 0.000303 0.000687 0.000665 0.001458
Bud Neck 0.005524 0.009813 0.014122 0.019895 0.003582 0.008338 0.010204 0.003610 0.004532 0.009014 0.013272 0.019547
Bud Site 0.001702 0.004680 0.003610 0.021048 0.001417 0.004188 0.004380 0.016589 0.001556 0.004413 0.003777 0.020953
Cell Periphery 0.000110 0.000183 0.000232 0.000702 0.000117 0.000155 0.000122 0.000347 0.000114 0.000168 0.000208 0.000694
Cytoplasm 0.162441 0.154902 0.053787 0.138265 0.154872 0.130384 0.019364 0.073631 0.158573 0.141618 0.046317 0.136885
Cytoplasmic Foci 0.022314 0.027318 0.002622 0.010867 0.017375 0.021897 0.001917 0.006688 0.019790 0.024381 0.002469 0.010777
Eisosomes 0.000030 0.000047 0.000037 0.000111 0.000028 0.000044 0.000041 0.000040 0.000029 0.000046 0.000038 0.000110
Endoplasmic Reticulum 0.000974 0.003081 0.003369 0.004872 0.000921 0.002620 0.006741 0.006209 0.000947 0.002831 0.004101 0.004901
Endosome 0.000855 0.003140 0.001035 0.019130 0.000810 0.002707 0.003170 0.026894 0.000832 0.002905 0.001498 0.019296
Golgi 0.000462 0.001115 0.000132 0.010109 0.000358 0.001795 0.001715 0.057651 0.000409 0.001483 0.000475 0.011124
Lipid Particles 0.002259 0.003843 0.000466 0.003002 0.002275 0.003174 0.000587 0.000390 0.002268 0.003481 0.000492 0.002946
Mitochondria 0.003709 0.004270 0.002148 0.022130 0.002958 0.005607 0.001834 0.060756 0.003326 0.004995 0.002080 0.022954
Mitotic Spindle 0.003835 0.009840 0.009268 0.099388 0.002865 0.010348 0.005795 0.032747 0.003339 0.010115 0.008514 0.097965
None 0.011286 0.018430 0.011111 0.020557 0.008395 0.010274 0.011611 0.007579 0.009809 0.014011 0.011219 0.020280
Nuclear Periphery 0.001177 0.001829 0.001117 0.006307 0.001352 0.001359 0.000878 0.001138 0.001266 0.001574 0.001065 0.006196
Nuclear Periphery Foci 0.000396 0.001529 0.000344 0.006497 0.000545 0.000752 0.000524 0.000745 0.000472 0.001108 0.000383 0.006374
Nucleolus 0.011809 0.017897 0.013526 0.004567 0.007637 0.015093 0.008690 0.001347 0.009677 0.016378 0.012476 0.004498
Nucleus 0.766812 0.724865 0.876944 0.543546 0.789788 0.769008 0.913637 0.593475 0.778553 0.748781 0.884907 0.544612
Peroxisomes 0.001264 0.002612 0.000375 0.004094 0.000906 0.002943 0.000528 0.000392 0.001081 0.002792 0.000408 0.004015
Vacuole 0.002667 0.008880 0.004860 0.047546 0.002964 0.007702 0.006519 0.036482 0.002819 0.008242 0.005220 0.047310
Vacuole Periphery 0.000263 0.001202 0.000309 0.015894 0.000345 0.000788 0.000797 0.072655 0.000305 0.000977 0.000415 0.017106

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.74 -12.05 -14.96 -8.95 -7.08 -0.68 -2.59 -2.47 -1.63 -0.35 -1.56 -3.51 -6.55 -4.19 -6.18
Bud Neck -4.31 -11.77 -10.78 -7.00 -1.01 -6.29 -8.25 -3.00 -1.89 -0.45 -7.17 -15.60 -12.61 -8.53 -1.67
Bud Site -3.56 -4.42 -8.89 -5.43 -6.56 -3.87 -3.58 -3.07 -1.83 -1.59 -5.25 -5.87 -9.33 -6.35 -6.64
Cell Periphery -5.08 -4.05 -3.54 -2.08 -1.95 -3.04 -0.29 -2.01 -1.17 -1.90 -5.78 -3.97 -3.52 -2.44 -2.27
Cytoplasm 1.16 20.91 11.11 9.07 -7.20 3.50 25.21 2.60 1.91 -1.35 3.39 29.52 12.52 9.29 -8.54
Cytoplasmic Foci -2.12 13.77 12.69 11.72 -2.54 -1.75 12.43 10.44 10.71 -0.52 -2.65 18.28 16.12 15.64 -3.08
Eisosomes -7.61 -4.56 -5.68 -3.33 -4.63 -5.92 -7.04 -3.80 -2.82 -2.00 -9.45 -7.78 -5.94 -3.86 -4.32
Endoplasmic Reticulum -13.73 -13.80 -20.22 -13.86 -10.57 -8.31 -12.02 -5.12 -4.49 -2.12 -14.45 -18.17 -20.93 -15.21 -8.39
Endosome -6.75 -0.62 -5.09 -2.59 -4.92 -5.82 -1.47 -1.32 -0.78 -0.99 -8.86 -1.55 -5.19 -2.99 -4.76
Golgi -1.54 1.88 -3.31 -2.21 -3.85 -2.26 -0.91 -0.98 -0.81 -0.93 -2.72 0.64 -3.56 -1.96 -3.74
Lipid Particles -4.57 7.94 2.27 5.94 -2.94 -1.54 6.73 4.66 5.22 -1.26 -3.91 10.55 2.69 5.37 -2.88
Mitochondria -0.66 1.62 -2.64 -2.44 -3.98 -2.48 1.60 -0.91 -0.58 -1.07 -2.33 1.93 -3.17 -2.06 -4.20
Mitotic Spindle -3.09 -3.92 -11.47 -9.91 -9.99 -3.88 -1.89 -2.24 -1.81 -2.06 -4.92 -4.65 -11.77 -10.32 -10.39
None -4.16 1.75 0.49 4.17 -1.02 -1.68 0.45 -0.60 -0.10 -0.74 -4.19 1.08 -0.63 2.27 -1.31
Nuclear Periphery -3.90 -2.57 -6.26 -4.97 -5.65 -0.58 -0.55 -1.76 -1.72 -1.72 -3.23 -2.13 -6.28 -5.63 -5.84
Nuclear Periphery Foci -5.22 -0.76 -3.36 -1.10 -2.92 -1.04 -0.79 -1.29 -0.82 -0.74 -4.54 -0.85 -3.34 -2.07 -2.95
Nucleolus -4.38 -3.27 3.84 7.84 6.88 -5.91 -1.07 1.90 5.36 2.37 -7.07 -5.03 2.70 8.19 6.48
Nucleus 4.58 -14.31 7.21 2.94 17.94 2.54 -13.16 1.13 0.71 3.30 4.88 -18.40 8.92 5.54 19.18
Peroxisomes -3.54 3.01 0.15 2.56 -1.48 -4.19 2.84 3.80 6.54 2.07 -5.42 4.10 -0.03 2.92 -1.47
Vacuole -7.65 -5.01 -14.95 -12.89 -13.75 -5.76 -5.16 -2.80 -2.54 -2.29 -9.35 -6.74 -15.10 -13.36 -13.55
Vacuole Periphery -2.57 -0.25 -3.87 -2.88 -3.85 -2.25 -0.35 -0.99 -0.94 -0.98 -3.41 -0.09 -3.95 -3.30 -3.94
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7
Localization
Cell Percentages nucleus (86%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Swd1

Swd1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Swd1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available