Standard name
Human Ortholog
Description Component of the U5 snRNP complex; required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.89 0.94 0.91 0.85 0.89 0.87 0.76 0.77 0.71 0.63 0.64 0.67 0.89 0.96 0.89 0.82 0.76 0.86 0.72 0.73 0.67 0.77 0.75 0.74
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.06 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.1 0 0 0.05 0 0.14 0.3 0.25 0.38 0.4 0.45 0.31 0 0 0 0 0 0 0.07 0.06 0.1 0.05 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0.05 0 0.06 0.05 0 0 0 0 0 0.08 0.07 0.06 0.06 0.05 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.09 0.07 0.11 0.11 0.08 0.06 0.07 0.08 0 0.08 0 0.07 0.1 0.09 0.13 0.23 0.31 0.19 0 0.05 0.06 0 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 2 3 0 1 1
Bud 1 1 0 0 1 1 5 4 2 9 5 6 0 0 0 0 0 1 3 5 1 1 6 9
Bud Neck 0 0 12 3 8 3 5 6 3 5 9 5 2 1 3 2 2 3 0 3 1 0 2 5
Bud Site 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 0 0 0 2 1 0 1 2 1 1 0 8 5 12 0 1 3 0 0 2
Cytoplasm 154 303 238 117 218 236 261 197 157 151 175 190 163 175 211 393 325 387 135 244 174 95 180 163
Endoplasmic Reticulum 1 0 0 0 3 0 1 0 0 0 0 0 0 1 0 33 24 28 2 2 2 2 1 1
Endosome 0 0 1 1 0 1 0 1 0 0 0 0 1 0 1 1 1 0 0 5 2 0 1 3
Golgi 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 1 0
Mitochondria 17 5 0 7 6 38 104 65 84 96 122 89 0 0 0 4 4 10 12 20 24 6 8 5
Nucleus 2 3 11 5 3 1 15 7 5 11 6 17 10 2 3 14 11 20 15 23 16 7 12 9
Nuclear Periphery 0 0 1 0 0 2 0 0 1 2 1 0 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0
SpindlePole 0 0 0 1 0 0 2 8 2 3 2 6 0 0 0 0 1 1 1 4 4 1 7 4
Vac/Vac Membrane 16 24 30 15 19 17 24 20 5 20 6 21 19 17 32 111 135 85 6 16 16 4 11 9
Unique Cell Count 173 324 262 138 245 272 344 255 220 239 273 284 183 182 238 479 429 452 188 335 259 125 240 220
Labelled Cell Count 191 337 295 149 258 300 418 310 262 297 327 336 196 197 251 568 509 548 188 335 259 125 240 220


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 4.9 5.5 4.7 5.1 4.2 4.0 4.3 3.2 3.9 3.4 3.9 5.7 6.3 6.2 8.0 7.7 7.2 5.9 6.2 6.5
Std Deviation (1e-4) 1.5 1.9 1.6 1.4 2.0 1.7 1.3 1.5 1.0 1.2 1.0 1.0 1.6 1.9 1.9 3.1 3.2 3.3 2.2 2.2 2.2
Intensity Change (Log2) – – – -0.23 -0.12 -0.39 -0.45 -0.34 -0.77 -0.48 -0.69 -0.5 0.05 0.19 0.16 0.54 0.49 0.39 0.1 0.17 0.23

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 3.9 6.0 2.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.8611 2.4758 2.4791 2.2258 1.8906 2.5298 1.6101 2.6137 2.0803 1.8372 1.8102 2.0871 4.8786 3.1236 1.9034 2.0311 2.0784 2.268
Actin 0.0127 0.0015 0.0015 0.0004 0.0037 0.0039 0.0009 0.0005 0.001 0.0003 0.0211 0.0015 0.0247 0.0025 0.0029 0.0539 0.0081 0.003
Bud 0.0014 0.0028 0.0006 0.0003 0.0006 0.0005 0.0002 0.0004 0.0003 0.0001 0.0001 0.0008 0.0013 0.0004 0.0005 0.0023 0.0501 0.0018
Bud Neck 0.0028 0.0013 0.0019 0.0012 0.0037 0.0046 0.0016 0.0015 0.001 0.0009 0.001 0.0042 0.0042 0.0006 0.0032 0.0029 0.0014 0.003
Bud Periphery 0.0024 0.003 0.001 0.0002 0.0006 0.0007 0.0001 0.0002 0.0002 0 0.0001 0.0003 0.0027 0.0006 0.0005 0.0022 0.022 0.0016
Bud Site 0.0053 0.01 0.0013 0.0004 0.0077 0.0004 0.0013 0.0038 0.0014 0.0002 0.0002 0.0003 0.0098 0.0042 0.0049 0.0038 0.0056 0.0003
Cell Periphery 0.0003 0.0002 0.0001 0 0.0002 0 0 0 0 0 0 0 0.0087 0.0076 0.0002 0.0001 0.0014 0.0017
Cytoplasm 0.2883 0.4113 0.3358 0.3346 0.2762 0.319 0.3098 0.393 0.3618 0.4802 0.3591 0.2671 0.4043 0.6412 0.5387 0.4745 0.4982 0.4405
Cytoplasmic Foci 0.0128 0.0071 0.0115 0.0083 0.0251 0.0097 0.0062 0.0027 0.0062 0.0041 0.0068 0.0048 0.011 0.0032 0.006 0.0218 0.0236 0.0052
Eisosomes 0.0002 0 0.0001 0 0.0001 0 0 0 0 0 0.0009 0 0.0003 0 0 0.0001 0 0
Endoplasmic Reticulum 0.0045 0.0036 0.0024 0.0021 0.0038 0.0022 0.0035 0.0033 0.0022 0.003 0.0016 0.0019 0.0141 0.0034 0.0037 0.0062 0.007 0.003
Endosome 0.012 0.0044 0.0058 0.0042 0.0243 0.0055 0.0048 0.0034 0.0026 0.0044 0.0052 0.0038 0.0286 0.002 0.0089 0.0446 0.0574 0.0054
Golgi 0.0026 0.0003 0.001 0.0001 0.0034 0.0006 0.0002 0.0001 0.0001 0.0001 0.0013 0.0003 0.0094 0.0003 0.0066 0.0555 0.0105 0.0035
Lipid Particles 0.0054 0.0002 0.0031 0.0002 0.0024 0.0009 0.0006 0.0002 0.0003 0 0.0037 0.0017 0.0111 0.0002 0.0013 0.0061 0.0282 0.0003
Mitochondria 0.0042 0.001 0.0048 0.001 0.0024 0.0021 0.0006 0.0005 0.0006 0.0006 0.0041 0.0005 0.0113 0.0003 0.01 0.0099 0.0135 0.0019
None 0.3676 0.2646 0.2972 0.1771 0.3756 0.2297 0.07 0.0525 0.06 0.0174 0.1385 0.0525 0.0622 0.0468 0.0696 0.0034 0.0067 0.0501
Nuclear Periphery 0.0164 0.0098 0.0082 0.0092 0.0139 0.0099 0.012 0.0144 0.0114 0.0134 0.0088 0.0107 0.0237 0.0097 0.0128 0.0099 0.0196 0.0129
Nucleolus 0.0016 0.0018 0.0029 0.0018 0.0013 0.0021 0.0016 0.0019 0.0017 0.0006 0.0011 0.0019 0.0009 0.001 0.0006 0.0006 0.0008 0.001
Nucleus 0.2325 0.2565 0.2946 0.4034 0.2171 0.3672 0.5654 0.4914 0.5165 0.4582 0.4114 0.5927 0.3399 0.2603 0.3178 0.2029 0.1979 0.4304
Peroxisomes 0.009 0.0015 0.0025 0.0004 0.002 0.0033 0.0003 0.0002 0.0008 0.0001 0.0085 0.0033 0.008 0.0004 0.001 0.0203 0.0173 0.0001
Punctate Nuclear 0.0136 0.0161 0.0209 0.0534 0.0324 0.0358 0.0186 0.0281 0.0306 0.015 0.0244 0.0504 0.0065 0.0077 0.0035 0.0738 0.0072 0.0256
Vacuole 0.0035 0.0027 0.0021 0.0012 0.0029 0.0014 0.002 0.0018 0.0011 0.0011 0.0014 0.001 0.0152 0.0072 0.0048 0.0035 0.0158 0.0071
Vacuole Periphery 0.001 0.0004 0.0004 0.0003 0.0007 0.0004 0.0004 0.0003 0.0002 0.0003 0.0004 0.0002 0.0019 0.0003 0.0023 0.0017 0.0076 0.0016

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.1989 7.3886 8.224 10.9063 13.3952 13.4235 9.8052 13.5508 11.0213 11.9742
Translational Efficiency 0.9603 0.8087 0.8631 0.6644 0.3919 0.486 0.7087 0.5103 0.6473 0.5832

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2155 1165 1925 103 2003 2162 761 1217 4158 3327 2686 1320

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 822.44 852.25 984.69 1136.28 752.18 860.82 1014.40 1080.95 788.59 857.82 993.11 1085.27
Standard Deviation 102.75 125.80 134.44 156.82 106.45 102.77 133.96 158.03 110.29 111.45 134.97 158.63
Intensity Change Log 2 — 0.051366 0.259759 0.466336 — 0.194634 0.431477 0.523150 — 0.121580 0.344340 0.493755

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000171 0.000333 0.000522 0.001394 0.000090 0.000360 0.000635 0.001588 0.000132 0.000350 0.000554 0.001573
Bud Neck 0.003775 0.003589 0.009000 0.004862 0.002479 0.006629 0.006238 0.025195 0.003151 0.005565 0.008217 0.023608
Bud Site 0.002517 0.003505 0.003729 0.003393 0.001346 0.005895 0.006425 0.029820 0.001953 0.005058 0.004493 0.027758
Cell Periphery 0.000088 0.000117 0.000118 0.000214 0.000135 0.000084 0.000205 0.000140 0.000111 0.000096 0.000142 0.000146
Cytoplasm 0.490814 0.467758 0.070534 0.074182 0.496987 0.461880 0.142511 0.115106 0.493788 0.463938 0.090926 0.111913
Cytoplasmic Foci 0.060462 0.035748 0.000298 0.000650 0.044592 0.029938 0.002550 0.006755 0.052817 0.031972 0.000936 0.006279
Eisosomes 0.000036 0.000031 0.000016 0.000045 0.000027 0.000024 0.000039 0.000025 0.000032 0.000026 0.000022 0.000026
Endoplasmic Reticulum 0.001339 0.003163 0.005629 0.011312 0.001298 0.001797 0.006668 0.005418 0.001319 0.002275 0.005923 0.005878
Endosome 0.002383 0.002883 0.000527 0.001180 0.001480 0.003164 0.001803 0.010395 0.001948 0.003066 0.000888 0.009676
Golgi 0.001018 0.000810 0.000091 0.000129 0.000429 0.001521 0.000631 0.004451 0.000734 0.001272 0.000244 0.004113
Lipid Particles 0.002359 0.002470 0.000213 0.000967 0.001941 0.000953 0.000839 0.000654 0.002157 0.001484 0.000391 0.000678
Mitochondria 0.002581 0.001488 0.001298 0.001012 0.002752 0.002723 0.001605 0.008079 0.002663 0.002291 0.001385 0.007528
Mitotic Spindle 0.002830 0.005594 0.003113 0.035102 0.002724 0.007387 0.011728 0.092570 0.002779 0.006759 0.005554 0.088086
None 0.004639 0.006331 0.003284 0.004613 0.006750 0.005013 0.009692 0.008624 0.005656 0.005474 0.005100 0.008311
Nuclear Periphery 0.000909 0.000976 0.001855 0.001618 0.000804 0.000985 0.001870 0.003310 0.000858 0.000982 0.001859 0.003178
Nuclear Periphery Foci 0.000642 0.001871 0.000266 0.001895 0.000755 0.000679 0.001013 0.001335 0.000697 0.001096 0.000477 0.001378
Nucleolus 0.000943 0.001116 0.000545 0.000359 0.000649 0.000908 0.000797 0.001036 0.000801 0.000981 0.000617 0.000984
Nucleus 0.396639 0.430381 0.888713 0.794067 0.415748 0.444261 0.774640 0.647867 0.405844 0.439401 0.856394 0.659275
Peroxisomes 0.001132 0.001367 0.000101 0.000118 0.000862 0.001470 0.000171 0.000833 0.001002 0.001434 0.000121 0.000777
Vacuole 0.024394 0.030031 0.009979 0.062767 0.017725 0.023825 0.028989 0.034135 0.021182 0.025999 0.015365 0.036369
Vacuole Periphery 0.000329 0.000439 0.000168 0.000120 0.000426 0.000504 0.000952 0.002664 0.000376 0.000481 0.000390 0.002465

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.88 -4.37 -7.87 -7.03 -5.23 -2.94 -9.36 -8.56 -5.00 -2.41 -3.42 -7.43 -9.00 -6.31 -3.88
Bud Neck -0.31 -7.08 -4.30 -3.99 2.42 -5.11 -4.77 -10.55 -7.06 -6.53 -4.58 -8.60 -10.47 -8.14 -4.49
Bud Site -1.89 -2.80 -3.39 -1.79 -0.25 -5.79 -3.50 -7.10 -4.02 -3.71 -5.51 -4.63 -6.86 -4.60 -4.44
Cell Periphery -3.02 -4.16 -6.74 -5.31 -5.24 0.83 -0.79 -0.22 -7.71 2.10 0.47 -1.02 -1.57 -7.91 -1.81
Cytoplasm 3.65 68.50 38.45 30.42 -0.55 4.43 43.06 55.71 49.91 2.33 5.72 84.37 73.24 59.20 -3.92
Cytoplasmic Foci 7.10 26.47 26.14 14.46 -4.50 5.50 21.25 21.07 17.62 -0.02 9.86 34.16 32.53 22.18 -3.19
Eisosomes 0.90 7.35 -4.97 -5.24 -7.13 0.44 -4.94 -3.23 -6.31 3.13 1.48 0.96 -4.22 -6.93 -6.84
Endoplasmic Reticulum -6.73 -16.51 -8.66 -7.26 -4.96 -2.03 -17.32 -17.13 -12.53 3.64 -5.02 -23.94 -18.42 -13.91 -0.37
Endosome -1.20 9.25 2.41 2.81 -4.52 -3.87 -0.35 -2.05 0.72 -1.81 -3.47 8.05 -1.19 0.82 -3.40
Golgi 0.71 3.04 2.78 2.75 -2.59 -2.10 0.40 -1.30 0.90 -1.42 -1.31 3.18 -0.33 0.77 -2.12
Lipid Particles -0.01 7.34 2.48 1.30 -6.87 3.91 3.90 3.70 -0.72 -0.71 2.39 8.99 5.59 1.68 -9.54
Mitochondria 1.23 1.41 1.70 0.15 1.45 0.06 1.74 -0.78 -0.95 -3.06 0.64 2.21 -0.84 -1.52 -3.14
Mitotic Spindle -1.60 -1.14 -1.77 -1.60 -1.69 -3.07 -2.27 -8.49 -7.06 -6.37 -3.47 -2.44 -8.67 -7.48 -7.94
None -1.58 2.08 0.73 2.11 -0.72 1.77 0.02 -2.16 -5.08 -2.06 0.49 2.34 -3.72 -4.73 -6.74
Nuclear Periphery -1.08 -14.93 -7.04 -6.45 -1.52 -1.36 -12.33 -17.36 -14.15 -7.82 -1.49 -20.28 -17.90 -15.74 -9.47
Nuclear Periphery Foci -4.70 3.69 -3.85 -0.93 -4.56 0.35 -2.79 -3.06 -3.05 -1.21 -3.32 1.98 -4.06 -1.55 -4.84
Nucleolus -0.50 2.29 3.45 3.98 1.09 -1.72 -0.44 -2.56 -0.30 -2.60 -1.44 1.67 -1.56 -0.01 -3.09
Nucleus -3.88 -70.23 -11.70 -9.89 6.50 -3.24 -33.98 -28.95 -25.81 6.04 -5.45 -78.66 -34.70 -28.97 16.32
Peroxisomes -0.96 6.24 5.88 5.13 -2.06 -1.64 3.19 2.65 4.18 -2.57 -1.80 6.45 5.23 5.75 -3.57
Vacuole -4.15 4.16 -5.83 -5.22 -6.22 -4.11 -7.85 -13.72 -11.79 -5.65 -5.12 -2.67 -14.34 -12.30 -12.96
Vacuole Periphery -0.94 2.25 2.91 3.35 0.16 -0.42 -0.24 -0.84 -0.63 -0.42 -0.94 1.06 -1.18 -0.66 -1.88
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the U5 snRNP complex; required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron
Localization
Cell Percentages cytoplasm (70%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Aar2

Aar2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Aar2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available