Standard name
Human Ortholog
Description Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0.07 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0
Cytoplasm 0.91 0.94 0.94 0.94 0.8 0.63 0.66 0.46 0.42 0.43 0.32 0.28 0.99 0.98 0.98 0.24 0.15 0.11 0.56 0.67 0.54 0.76 0.73 0.74
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.21 0.22 0.2 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Mitochondria 0.16 0 0.06 0.13 0.2 0.44 0.42 0.57 0.66 0.62 0.73 0.74 0 0 0 0.16 0.17 0.13 0.19 0.19 0.26 0.13 0.11 0.09
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.16 0.14 0.2 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0.05 0.09 0.05 0 0.06 0 0 0 0 0.24 0.29 0.26 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.14 0.19 0.06 0 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 3 4 8 2 4 2
Bud 3 3 6 4 5 11 11 20 14 9 4 3 0 0 0 18 6 10 2 2 2 0 10 8
Bud Neck 2 1 8 1 10 6 5 7 0 3 3 0 0 0 0 4 1 1 0 2 1 0 2 5
Bud Site 0 0 1 0 1 1 4 8 4 2 1 2 0 0 0 4 10 5 – – – – – –
Cell Periphery 2 2 0 0 0 1 2 0 2 6 1 4 0 1 0 26 12 22 0 2 4 0 4 2
Cytoplasm 152 277 226 172 207 159 237 123 86 107 49 39 266 362 421 152 63 35 119 212 122 135 227 199
Endoplasmic Reticulum 0 2 3 0 1 1 0 0 0 1 4 0 1 2 1 33 22 14 6 0 1 1 0 1
Endosome 2 1 0 0 1 0 0 0 0 0 0 0 1 2 3 133 91 62 7 5 4 2 1 3
Golgi 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 14 9 14 1 0 0 0 1 1
Mitochondria 26 12 15 24 51 112 152 154 134 153 112 102 0 4 2 100 70 41 41 58 59 22 34 25
Nucleus 0 1 0 3 1 0 2 1 0 1 0 2 1 2 1 15 17 6 0 0 1 0 0 0
Nuclear Periphery 1 0 0 1 0 1 0 1 0 2 3 1 0 1 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 2 1 0 3 2 1 0 0 0 0 0 3 1 3 0 0 0 0 0 0
Peroxisomes 0 1 0 0 1 0 0 2 1 0 0 0 0 0 0 102 59 62 0 0 0 0 0 0
SpindlePole 0 0 1 1 10 7 18 24 10 8 9 4 0 1 1 150 119 79 6 5 4 3 12 1
Vac/Vac Membrane 0 4 0 0 0 1 1 3 3 2 0 6 1 0 2 76 59 58 13 10 5 2 4 13
Unique Cell Count 167 295 240 183 258 252 359 268 204 248 154 137 268 370 429 622 407 307 212 315 226 178 313 271
Labelled Cell Count 188 306 261 206 290 301 432 346 256 295 186 163 270 375 432 831 540 412 212 315 226 178 313 271


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.1 3.6 2.8 2.7 3.1 2.6 2.4 2.8 2.8 2.5 2.6 2.9 4.0 3.8 3.8 5.3 6.2 6.2 3.5 3.8 4.2
Std Deviation (1e-4) 0.7 0.7 0.5 1.0 1.2 0.7 1.1 1.1 1.2 0.9 0.9 1.4 1.6 1.3 1.2 1.4 1.4 1.5 1.0 1.4 1.2
Intensity Change (Log2) – – – -0.07 0.15 -0.15 -0.25 -0.02 -0.03 -0.19 -0.13 0.04 0.5 0.42 0.43 0.89 1.13 1.13 0.31 0.41 0.58

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 5.7 6.2 7.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.1495 0.0066 0.0012 0.0026 0.0006 0.0435 0.0427 0.0142 0.011 0.0094 0.0076 0.0061 0 0.0057 0.0002 0.0094 0.0005 0.0002
Bud 0.0012 0.0004 0.0004 0.0159 0.0071 0.0006 0.0005 0.0005 0.0011 0.0143 0.0005 0.0019 0 0.0007 0 0.0009 0.0001 0
Bud Neck 0.008 0.0002 0.0001 0.0003 0.0001 0.0027 0.0006 0.0005 0.0038 0.0022 0.0002 0.0005 0 0.0004 0.0002 0.0009 0 0.0001
Bud Periphery 0.0038 0.0008 0.0035 0.0559 0.0252 0.0024 0.0015 0.0006 0.0017 0.0054 0.0026 0.0023 0 0.0013 0 0.0022 0.0002 0
Bud Site 0.0133 0.0006 0.0007 0.0078 0.0003 0.0003 0.0018 0.0106 0.0092 0.0332 0.0004 0.0013 0 0.0125 0.0003 0.0007 0 0
Cell Periphery 0.014 0.0014 0.0025 0.0021 0.0006 0.0005 0.0006 0.0006 0.0007 0.0008 0.0001 0.0001 0 0.0013 0.0002 0.0008 0.0001 0.0001
Cytoplasm 0.1795 0.1943 0.1561 0.3252 0.1168 0.1363 0.0209 0.0631 0.0602 0.0498 0.0408 0.0769 0.0121 0.1361 0.0424 0.0536 0.042 0.0786
Cytoplasmic Foci 0.0836 0.0115 0.007 0.0179 0.0182 0.0439 0.0687 0.0192 0.0427 0.0407 0.06 0.0368 0.0008 0.0111 0.0077 0.0182 0.0061 0.0324
Eisosomes 0.0119 0.0012 0.0014 0.0002 0.0005 0.0005 0.0005 0.0006 0.0005 0.0005 0.0006 0.0001 0.0001 0.0004 0.0003 0.0002 0.0002 0.0001
Endoplasmic Reticulum 0.0773 0.0033 0.0026 0.0056 0.0102 0.0117 0.0018 0.0017 0.0015 0.0023 0.0011 0.001 0.0001 0.0012 0.0012 0.0012 0.0014 0.0018
Endosome 0.0498 0.007 0.0019 0.0182 0.015 0.0155 0.0484 0.0044 0.0362 0.0126 0.0124 0.0097 0 0.0034 0.0024 0.0387 0.0193 0.0154
Golgi 0.0346 0.0075 0.0006 0.0051 0.0038 0.0051 0.0153 0.005 0.0226 0.0073 0.0039 0.0045 0 0.0079 0.0004 0.0353 0.0073 0.0008
Lipid Particles 0.0665 0.0016 0.001 0.0005 0.0028 0.0041 0.0276 0.0019 0.0065 0.0152 0.018 0.0036 0 0.0003 0.0011 0.014 0.0035 0.008
Mitochondria 0.0057 0.0037 0.002 0.123 0.0917 0.0536 0.0119 0.003 0.0092 0.0068 0.0028 0.002 0 0.003 0.0002 0.0835 0.1571 0.0004
None 0.2698 0.7574 0.8157 0.4013 0.6951 0.648 0.6696 0.8645 0.7756 0.7596 0.7832 0.8423 0.9865 0.8132 0.9416 0.7196 0.7575 0.8589
Nuclear Periphery 0.0064 0.0003 0.0003 0.0018 0.0006 0.0012 0.005 0.0004 0.0006 0.0027 0.0007 0.0003 0 0.0002 0.0002 0.0004 0.0004 0.0004
Nucleolus 0.0017 0.0002 0.0005 0.0005 0.0002 0.0002 0.0013 0.0005 0.0004 0.004 0.0003 0.0001 0 0.0001 0.0001 0.0006 0.0001 0.0001
Nucleus 0.0026 0.0003 0.0005 0.0043 0.0006 0.0005 0.0019 0.0005 0.0007 0.0063 0.0003 0.0008 0 0.0002 0.0002 0.0009 0.0001 0.0001
Peroxisomes 0.0067 0.0005 0.0005 0.0013 0.0014 0.0239 0.0432 0.0047 0.0105 0.0164 0.0616 0.0075 0 0.0003 0.0001 0.0045 0.0007 0.0007
Punctate Nuclear 0.0062 0.0002 0.0003 0.0005 0.0002 0.0027 0.0192 0.0018 0.001 0.0071 0.0019 0.0014 0 0.0001 0.0002 0.0002 0.0001 0.001
Vacuole 0.0065 0.0008 0.0009 0.0067 0.005 0.0014 0.0124 0.0015 0.0036 0.0026 0.0006 0.0006 0 0.0004 0.0006 0.011 0.0013 0.0006
Vacuole Periphery 0.0014 0.0002 0.0001 0.0033 0.0039 0.0012 0.0045 0.0002 0.0008 0.0009 0.0003 0.0001 0 0.0001 0.0001 0.0032 0.002 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 4.7502 6.0663 10.8034 7.9561 9.2383 8.1387 10.7338 12.0053 10.8046 10.9316
Translational Efficiency 1.0373 0.8096 0.3896 0.5288 0.3655 0.7603 0.6316 0.5896 0.5608 0.4814

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1347 1501 1437 1959 1598 246 222 2514 2945 1747 1659 4473

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1541.78 1682.63 1951.52 2692.55 1750.66 1976.19 2492.81 2763.29 1655.12 1723.97 2023.95 2732.31
Standard Deviation 321.78 500.70 541.23 574.82 416.42 559.83 426.68 612.14 390.23 519.57 558.62 597.11
Intensity Change Log 2 — 0.126121 0.340001 0.804376 — 0.174823 0.509874 0.658488 — 0.152221 0.432809 0.728644

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000502 0.000504 0.000589 0.000630 0.000490 0.000607 0.000748 0.000509 0.000495 0.000518 0.000610 0.000562
Bud Neck 0.006385 0.004518 0.009988 0.018601 0.003505 0.004373 0.011318 0.019010 0.004822 0.004497 0.010166 0.018831
Bud Site 0.000550 0.000502 0.000853 0.001541 0.000393 0.000772 0.001095 0.002451 0.000465 0.000540 0.000885 0.002053
Cell Periphery 0.000061 0.000138 0.000039 0.000112 0.000037 0.000033 0.000043 0.000238 0.000048 0.000123 0.000040 0.000183
Cytoplasm 0.000218 0.001100 0.000804 0.000560 0.000178 0.000304 0.000055 0.000914 0.000196 0.000988 0.000704 0.000759
Cytoplasmic Foci 0.000080 0.000153 0.000259 0.000802 0.000457 0.001424 0.000303 0.001249 0.000284 0.000332 0.000265 0.001053
Eisosomes 0.000091 0.000110 0.000092 0.000051 0.000163 0.000097 0.000133 0.000062 0.000130 0.000108 0.000097 0.000057
Endoplasmic Reticulum 0.000756 0.000426 0.000231 0.000402 0.000364 0.000392 0.000294 0.000545 0.000543 0.000421 0.000239 0.000482
Endosome 0.000088 0.000028 0.000011 0.000573 0.000040 0.000176 0.000009 0.000492 0.000062 0.000049 0.000011 0.000528
Golgi 0.000066 0.000037 0.000052 0.000744 0.000083 0.000139 0.000059 0.000643 0.000075 0.000051 0.000053 0.000688
Lipid Particles 0.000019 0.000005 0.000005 0.000041 0.000053 0.000059 0.000006 0.000066 0.000037 0.000013 0.000005 0.000055
Mitochondria 0.001028 0.000963 0.001454 0.002496 0.000822 0.001180 0.001923 0.001722 0.000916 0.000994 0.001517 0.002061
Mitotic Spindle 0.001067 0.000077 0.000085 0.003702 0.000410 0.008692 0.000031 0.008529 0.000710 0.001290 0.000078 0.006415
None 0.001389 0.003055 0.000850 0.001003 0.000819 0.002212 0.000738 0.001256 0.001080 0.002936 0.000835 0.001145
Nuclear Periphery 0.000047 0.000050 0.000045 0.000341 0.000020 0.000142 0.000040 0.000276 0.000033 0.000063 0.000045 0.000305
Nuclear Periphery Foci 0.000055 0.000045 0.000012 0.000080 0.000063 0.000330 0.000002 0.000072 0.000060 0.000085 0.000010 0.000076
Nucleolus 0.058002 0.050637 0.048664 0.016444 0.062376 0.069899 0.033426 0.015801 0.060375 0.053349 0.046625 0.016083
Nucleus 0.927376 0.934823 0.932281 0.950057 0.926138 0.901931 0.945366 0.944127 0.926704 0.930191 0.934032 0.946724
Peroxisomes 0.001391 0.001871 0.003303 0.000782 0.002764 0.006414 0.003960 0.000456 0.002136 0.002511 0.003391 0.000599
Vacuole 0.000450 0.000514 0.000192 0.000574 0.000455 0.000534 0.000303 0.001053 0.000453 0.000517 0.000207 0.000843
Vacuole Periphery 0.000378 0.000444 0.000192 0.000465 0.000371 0.000290 0.000146 0.000530 0.000374 0.000422 0.000186 0.000501

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.18 -5.74 -7.41 -6.97 -3.48 -3.07 -7.43 -4.53 -0.38 4.58 -1.29 -8.02 -8.20 -6.56 -0.87
Bud Neck 4.49 -8.76 -18.11 -20.22 -13.24 -1.59 -9.88 -22.22 -15.74 -6.67 0.66 -15.80 -28.53 -27.73 -17.02
Bud Site 0.41 -6.13 -5.99 -6.05 -4.57 -1.02 -5.70 -7.39 -2.30 -3.78 -1.06 -8.27 -9.44 -8.10 -7.06
Cell Periphery -1.38 1.65 -2.58 0.44 -4.38 0.21 -1.02 -3.50 -3.51 -3.28 -1.59 1.00 -4.10 -0.83 -4.42
Cytoplasm -1.79 -0.95 -2.44 0.51 -0.05 -1.01 1.55 -5.63 -3.80 -7.38 -1.89 -0.96 -5.35 0.13 -0.44
Cytoplasmic Foci -1.99 -5.65 -3.05 -2.76 -2.17 -1.01 0.20 -1.41 0.67 -1.87 -0.53 -0.17 -2.67 -1.66 -3.01
Eisosomes -1.28 -1.12 6.42 3.69 8.21 5.03 0.84 8.75 4.84 8.55 1.59 3.70 10.47 3.90 11.63
Endoplasmic Reticulum 3.41 9.29 5.04 -0.53 -13.09 -0.53 0.10 -4.06 -2.57 -4.08 1.63 9.72 0.05 -1.58 -9.06
Endosome 1.33 1.72 -1.69 -2.04 -2.13 -1.25 1.45 -2.45 -0.79 -2.72 0.24 2.24 -2.89 -2.97 -3.41
Golgi 1.49 0.36 -1.81 -1.92 -1.84 -0.71 0.12 -1.43 -1.21 -1.47 0.84 0.54 -2.23 -2.36 -2.31
Lipid Particles 1.49 1.50 -1.30 -2.54 -2.54 -0.34 1.13 -0.16 0.21 -1.71 1.06 1.48 -0.52 -2.01 -2.56
Mitochondria 0.59 -4.47 -6.43 -7.14 -4.83 -2.75 -8.78 -8.69 -4.71 0.76 -1.22 -10.07 -10.09 -9.90 -5.21
Mitotic Spindle 1.31 1.22 -2.84 -4.18 -4.13 -1.59 1.62 -5.75 -0.23 -6.02 -0.70 1.58 -6.33 -5.05 -7.23
None -1.97 1.57 0.53 2.37 -4.22 -1.36 0.31 -3.46 0.71 -5.93 -2.63 1.29 -1.52 2.29 -6.41
Nuclear Periphery -0.16 -0.14 -4.52 -4.48 -4.51 -1.13 -4.69 -9.37 -2.24 -8.23 -1.65 -3.30 -8.41 -7.30 -8.03
Nuclear Periphery Foci 0.38 2.36 -1.15 -1.44 -2.99 -1.79 2.08 -0.39 1.73 -5.55 -0.73 2.66 -1.00 0.01 -5.30
Nucleolus 1.90 1.48 10.67 9.56 9.71 -1.03 5.10 13.09 6.85 3.47 2.17 3.33 16.93 12.66 11.43
Nucleus -1.66 0.14 -1.51 0.12 -1.74 2.42 -1.87 -1.14 -2.90 1.08 -0.77 -0.45 -1.82 -0.81 -1.23
Peroxisomes -2.39 -7.01 2.12 3.69 7.67 -3.89 -2.53 8.60 6.38 5.89 -1.56 -5.38 8.54 8.03 10.08
Vacuole -0.29 2.17 -1.56 -1.17 -3.28 -0.48 0.11 -1.26 -0.50 -1.52 -0.24 1.75 -1.74 -1.54 -3.23
Vacuole Periphery -0.53 2.66 -0.11 0.24 -1.20 0.45 1.78 -0.37 -0.75 -1.77 -0.40 2.53 -0.37 -0.02 -2.00
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog
Localization
Cell Percentages nucleus (99%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Pet112

Pet112


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pet112-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available