Standard name
Human Ortholog
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 – 0 0 0 0.05 0.1 0.11 0.18 0.11 0 0.05 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.06 0 0 0 0.21 0 – 0.13 0.07 0.09 0.08 0 0.05 0 0 0 0 0 0 0 0 0 0
Nucleus 0.82 0.9 0.94 0.91 0.87 0.81 0.87 – 0.82 0.77 0.8 0.74 0.86 0.78 0.71 0.81 0.89 0.78 0.75 0.87 0.79 0.64 0.63 0.56
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.32 0.13 0.13 0.12 0.1 0.27 0.16 – 0.39 0.3 0.31 0.36 0.13 0.18 0.12 0.14 0.15 0.08 0.17 0.06 0.15 0.27 0.24 0.3
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0.06 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 1 0 0 0 1 2 0
Bud 0 1 0 0 0 1 1 – 0 2 0 0 0 1 0 1 0 2 3 2 0 2 6 3
Bud Neck 0 0 0 1 0 1 0 – 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 1 0 0 2 2 1 0 – 1 8 6 5 1 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 8 12 3 5 10 7 9 – 1 7 4 14 21 48 68 12 3 6 0 1 1 1 1 2
Endoplasmic Reticulum 0 0 0 1 0 0 0 – 0 0 0 0 0 0 0 1 0 1 0 0 0 1 2 0
Endosome 1 4 0 1 0 0 2 – 0 0 0 0 0 1 6 0 1 3 7 5 1 1 4 5
Golgi 0 0 0 0 1 0 0 – 0 0 0 0 0 0 0 0 1 1 5 0 1 1 0 2
Mitochondria 6 31 0 1 1 56 7 – 34 20 22 24 0 20 0 2 1 4 2 4 2 1 3 4
Nucleus 373 501 239 164 250 219 271 – 219 212 195 223 182 333 271 91 84 90 370 537 219 189 273 252
Nuclear Periphery 2 2 0 1 2 2 1 – 3 4 1 0 2 2 3 1 0 0 0 0 0 0 2 1
Nucleolus 144 71 33 22 28 74 51 – 104 83 76 108 28 76 46 16 14 9 84 38 42 81 104 138
Peroxisomes 1 2 0 0 0 0 0 – 0 0 0 0 0 1 7 0 0 1 0 0 0 0 0 0
SpindlePole 1 4 6 0 0 0 4 – 1 0 1 2 2 4 8 1 0 0 3 4 1 1 5 10
Vac/Vac Membrane 5 5 1 1 3 2 2 – 0 1 2 0 1 2 3 2 1 7 10 18 6 11 23 28
Unique Cell Count 455 558 255 181 286 271 311 266 274 243 301 211 426 382 112 94 115 492 617 279 297 433 454
Labelled Cell Count 542 633 282 199 297 363 348 364 337 307 377 237 489 412 128 105 125 492 617 279 297 433 454


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.3 7.5 8.1 7.8 8.4 5.6 7.2 – 6.4 6.7 6.7 6.7 9.1 7.7 9.3 11.0 11.6 11.8 7.8 8.7 9.0
Std Deviation (1e-4) 2.2 1.6 1.5 1.5 1.7 1.5 1.5 – 1.4 1.5 1.5 1.6 2.5 2.6 2.8 2.8 2.6 2.4 1.9 1.7 1.8
Intensity Change (Log2) – – – -0.04 0.05 -0.53 -0.17 – -0.35 -0.27 -0.26 -0.27 0.17 -0.08 0.2 0.44 0.51 0.54 -0.05 0.1 0.15

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 1.8 0 1.4 – 0 0 0 2.4 4.3 4.8 6.5 0 0 0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 7.7 0 – 5.9 4.4 4.9 4.6 0 3.5 0 0 0 0
Nucleus -1.2 -2.5 -4.4 -2.6 – -4.0 -5.3 -4.5 -6.2 -2.7 -5.4 -7.1 -3.7 -1.4 -4.4
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus -0.2 -1.2 4.1 1.2 – 6.8 4.8 4.9 6.2 0.1 1.7 -0.3 0.3 0.5 -1.4
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 -0.2 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.1513 2.2593 1.7698 1.4441 1.3277 2.0219 3.935 3.9355 3.908 3.3634 3.9954 3.8006 7.4738 8.2516 7.3008 6.9649 6.8536 6.9288
Actin 0.0062 0 0.0017 0.0013 0.0001 0 0.0293 0 0.0123 0.0041 0.0217 0.0004 0.001 0 0 0 0.0002 0
Bud 0.001 0.0002 0.0001 0.0002 0.0001 0 0.0005 0 0.0002 0.0004 0.0016 0.0002 0 0 0 0 0.0001 0
Bud Neck 0.0019 0.0001 0.0003 0.0001 0.0005 0.0011 0.0017 0.0001 0.0006 0.0004 0.0025 0.0009 0.0001 0.0001 0.0001 0 0.0009 0.0003
Bud Periphery 0.0034 0.0002 0.0007 0.0003 0.0002 0.0001 0.0014 0 0.0002 0.0011 0.0049 0.0012 0 0 0 0 0.0001 0
Bud Site 0.0041 0.0002 0.0001 0.0011 0.0002 0.0001 0.0018 0 0.0034 0.0008 0.0027 0.0002 0.0001 0 0 0 0.0001 0
Cell Periphery 0.0004 0 0.0004 0 0.0001 0 0.0003 0 0.0001 0.0003 0.0005 0.0001 0 0 0 0 0 0
Cytoplasm 0.0015 0 0.0002 0.0003 0.0001 0 0.0067 0.0001 0.0006 0.0007 0.0015 0.0001 0.0019 0.0001 0 0 0.0001 0
Cytoplasmic Foci 0.0035 0 0.0001 0.0087 0 0 0.01 0 0.0027 0.0008 0.0026 0.0004 0.0004 0 0 0 0 0
Eisosomes 0.0002 0 0.0002 0 0 0 0.0002 0 0.0001 0.0001 0.0004 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0008 0 0.0003 0.0002 0 0 0.0073 0 0.0007 0.0039 0.0033 0.0001 0.0016 0 0 0 0 0
Endosome 0.0104 0 0.0009 0.0153 0.0001 0.0001 0.02 0 0.0032 0.0087 0.0102 0.0018 0.006 0 0 0 0.0001 0
Golgi 0.0039 0 0.0003 0.005 0 0 0.0033 0 0.0021 0.0024 0.0108 0.0009 0.0002 0 0 0 0 0
Lipid Particles 0.0089 0 0.0007 0.0224 0 0 0.0119 0 0.0056 0.0037 0.032 0.0097 0.0002 0 0 0 0 0
Mitochondria 0.0168 0.0002 0.0079 0.0076 0.0006 0.0004 0.0023 0.0001 0.0048 0.03 0.0495 0.007 0.0005 0.0001 0.0001 0.0001 0.0006 0.0001
None 0.0032 0 0.003 0.0008 0.0001 0 0.0026 0 0.0008 0.0004 0.0007 0.0001 0.0011 0 0 0 0.0001 0
Nuclear Periphery 0.015 0.0004 0.0052 0.0019 0.0012 0.001 0.0138 0.0007 0.0027 0.0129 0.0251 0.001 0.0131 0.0007 0.0003 0.0003 0.0023 0.0001
Nucleolus 0.0412 0.0272 0.03 0.0143 0.1756 0.108 0.05 0.0189 0.0199 0.0127 0.2249 0.0688 0.0246 0.0186 0.0199 0.0136 0.1266 0.0602
Nucleus 0.8544 0.9668 0.9452 0.902 0.8186 0.8883 0.8244 0.9793 0.9317 0.9065 0.5659 0.9048 0.9469 0.9799 0.9793 0.9858 0.8607 0.9376
Peroxisomes 0.0036 0 0.0002 0.0117 0 0 0.001 0 0.0049 0.0004 0.0033 0.0005 0 0 0 0 0 0
Punctate Nuclear 0.0118 0.0042 0.0009 0.0057 0.0023 0.0005 0.0085 0.0008 0.0029 0.0055 0.0303 0.0007 0.001 0.0003 0.0003 0.0002 0.0078 0.0015
Vacuole 0.0045 0.0003 0.0009 0.0005 0.0002 0.0001 0.0019 0 0.0004 0.0023 0.003 0.0006 0.0005 0 0 0 0.0001 0
Vacuole Periphery 0.003 0.0001 0.0009 0.0006 0.0001 0.0001 0.0009 0 0.0002 0.0018 0.0026 0.0005 0.0006 0 0 0 0.0001 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 43.2708 38.6814 36.4311 40.2206 33.4457 28.2768 42.8714 37.5651 38.9524 42.1167
Translational Efficiency 1.698 1.773 1.5849 1.2335 1.7238 2.496 1.329 1.934 1.6134 1.6313

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
238 121 2506 1 1893 45 230 1555 2131 166 2736 1556

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 804.23 964.36 1038.83 298.07 830.85 951.06 1057.00 1139.72 827.88 960.75 1040.36 1139.18
Standard Deviation 132.50 161.88 170.39 — 134.75 132.70 130.28 174.03 134.76 154.63 167.47 175.28
Intensity Change Log 2 — 0.261964 0.369280 -1.431957 — 0.194948 0.347315 0.456019 — 0.228300 0.358160 -0.185508

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000533 0.001566 0.000501 0.000017 0.000525 0.001135 0.001484 0.000803 0.000526 0.001449 0.000583 0.000802
Bud Neck 0.003037 0.014104 0.022641 0.000001 0.006092 0.007062 0.009701 0.029280 0.005751 0.012195 0.021554 0.029262
Bud Site 0.002066 0.001112 0.000857 0.000006 0.001429 0.002124 0.001633 0.004561 0.001500 0.001387 0.000922 0.004558
Cell Periphery 0.000078 0.000046 0.000035 0.000124 0.000183 0.000069 0.000059 0.000129 0.000171 0.000052 0.000037 0.000129
Cytoplasm 0.000616 0.000179 0.000309 0.000005 0.000881 0.021823 0.000926 0.004613 0.000851 0.006047 0.000361 0.004610
Cytoplasmic Foci 0.000367 0.002378 0.000006 0.000002 0.000264 0.000906 0.000066 0.001689 0.000276 0.001979 0.000011 0.001688
Eisosomes 0.000037 0.000042 0.000045 0.000174 0.000059 0.000048 0.000060 0.000034 0.000057 0.000043 0.000046 0.000034
Endoplasmic Reticulum 0.002239 0.003430 0.001429 0.000000 0.002198 0.005167 0.008054 0.003863 0.002202 0.003901 0.001986 0.003860
Endosome 0.000430 0.000229 0.000044 0.000000 0.000255 0.000593 0.000277 0.002185 0.000274 0.000327 0.000063 0.002183
Golgi 0.000119 0.001140 0.000059 0.000001 0.000190 0.000301 0.000116 0.001652 0.000182 0.000912 0.000064 0.001651
Lipid Particles 0.000365 0.000725 0.000011 0.000002 0.000258 0.001623 0.000318 0.000304 0.000270 0.000968 0.000037 0.000304
Mitochondria 0.000923 0.001699 0.001037 0.000006 0.000952 0.002556 0.001229 0.002182 0.000948 0.001931 0.001053 0.002180
Mitotic Spindle 0.000090 0.003771 0.000470 0.000043 0.002022 0.014843 0.000432 0.015775 0.001807 0.006772 0.000467 0.015765
None 0.003060 0.001147 0.000971 0.999530 0.004333 0.003861 0.001327 0.003023 0.004190 0.001882 0.001001 0.003663
Nuclear Periphery 0.000095 0.000154 0.000140 0.000000 0.000161 0.004903 0.000443 0.001327 0.000153 0.001441 0.000165 0.001327
Nuclear Periphery Foci 0.000483 0.000090 0.000022 0.000000 0.000363 0.006597 0.000177 0.001115 0.000376 0.001854 0.000035 0.001115
Nucleolus 0.086172 0.106515 0.031405 0.000000 0.100560 0.052436 0.027344 0.008264 0.098953 0.091855 0.031064 0.008258
Nucleus 0.895803 0.859292 0.939409 0.000001 0.877782 0.864349 0.941780 0.911944 0.879795 0.860663 0.939609 0.911358
Peroxisomes 0.001369 0.001829 0.000284 0.000089 0.000896 0.001656 0.000979 0.000270 0.000949 0.001782 0.000342 0.000270
Vacuole 0.001398 0.000310 0.000203 0.000000 0.000338 0.004901 0.003447 0.004486 0.000456 0.001554 0.000475 0.004484
Vacuole Periphery 0.000721 0.000244 0.000122 0.000000 0.000261 0.003048 0.000149 0.002500 0.000312 0.001004 0.000124 0.002498

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin NaN NaN NaN NaN NaN -2.17 -8.52 -5.76 1.18 5.53 -2.78 -2.69 -6.15 1.48 -5.16
Bud Neck NaN NaN NaN NaN NaN -0.55 -6.53 -17.06 -9.13 -10.98 -4.02 -21.65 -17.33 -8.95 -5.83
Bud Site NaN NaN NaN NaN NaN -1.17 -2.10 -4.97 -2.19 -3.47 -0.13 0.66 -4.87 -5.35 -6.70
Cell Periphery NaN NaN NaN NaN NaN 2.22 2.67 1.33 -1.99 -4.51 3.07 3.71 1.16 -4.94 -8.60
Cytoplasm NaN NaN NaN NaN NaN -1.23 -1.87 -5.94 0.95 -4.65 -1.11 1.80 -6.00 0.09 -6.58
Cytoplasmic Foci NaN NaN NaN NaN NaN -1.61 2.15 -2.30 -0.06 -3.11 -0.99 3.07 -2.28 0.56 -3.29
Eisosomes NaN NaN NaN NaN NaN 0.11 -1.15 5.91 1.99 6.25 2.13 2.73 5.69 1.94 5.62
Endoplasmic Reticulum NaN NaN NaN NaN NaN -3.18 -9.75 -10.40 1.25 6.25 -3.93 -0.31 -10.48 -0.97 -10.59
Endosome NaN NaN NaN NaN NaN -2.31 -1.95 -3.39 -1.52 -2.92 -0.78 2.99 -3.33 -2.91 -4.02
Golgi NaN NaN NaN NaN NaN -1.01 0.75 -1.48 -1.16 -1.61 -0.99 1.71 -1.50 -0.03 -1.74
Lipid Particles NaN NaN NaN NaN NaN -1.17 -0.50 0.15 1.19 1.02 -1.25 1.61 0.22 1.32 -2.09
Mitochondria NaN NaN NaN NaN NaN -1.39 -2.09 -5.96 -0.10 -5.22 -2.28 -1.27 -6.44 -1.64 -9.09
Mitotic Spindle NaN NaN NaN NaN NaN -1.43 0.83 -4.78 0.80 -5.32 -1.58 1.37 -4.94 -0.51 -5.68
None NaN NaN NaN NaN NaN 0.32 3.89 1.72 0.33 -4.13 2.86 5.02 0.53 -2.06 -3.66
Nuclear Periphery NaN NaN NaN NaN NaN -1.16 -7.13 -7.80 0.82 -4.08 -1.17 -2.91 -7.86 -0.09 -7.47
Nuclear Periphery Foci NaN NaN NaN NaN NaN -1.29 0.79 -1.20 1.22 -1.90 -1.10 2.62 -1.17 0.85 -2.89
Nucleolus NaN NaN NaN NaN NaN 6.01 16.96 31.06 4.95 3.71 0.84 21.19 32.80 8.86 16.87
Nucleus NaN NaN NaN NaN NaN 0.75 -10.11 -6.11 -1.75 4.10 1.63 -14.56 -5.74 -3.72 4.93
Peroxisomes NaN NaN NaN NaN NaN -0.95 0.52 3.98 1.47 4.37 -2.02 3.82 4.74 3.71 4.06
Vacuole NaN NaN NaN NaN NaN -2.86 -5.17 -7.44 0.17 0.33 -2.35 -1.57 -7.17 -4.19 -6.86
Vacuole Periphery NaN NaN NaN NaN NaN -1.33 1.36 -2.49 0.67 -2.72 -1.19 2.08 -2.37 -0.75 -2.80
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme
Localization
Cell Percentages nucleus (97%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Rox3

Rox3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rox3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available