Standard name
Human Ortholog
Description Hexaprenyl pyrophosphate synthetase; catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0.09 0.09 0.12 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.25 0.19 0.17 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.07 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0.05 0 0 0 – 0 0 0 0 0 0 0 0.07 0.06 0.06 0.07 0.05 0 0.05 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0.28 0.4 0.48 0.1 0.17 0.14 0 0.06 0.05 0 0.05 0.07
Mitochondria 0.89 0.93 0.89 0.96 0.85 0.92 0.91 0.89 – 0.93 0.94 0.95 0.8 0.66 0.53 0.1 0.06 0.05 0.78 0.73 0.76 0.71 0.71 0.7
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0.08 0 0.06 0.09 0.07 0.12 – 0.12 0.1 0.14 0.07 0 0 0.07 0.09 0.11 0 0 0 0 0 0
Nucleolus 0.21 0 0.05 0 0 0.1 0.11 0.12 – 0.13 0.1 0.09 0 0 0 0 0 0.05 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0.06 0 0 0 – 0 0 0 0 0 0 0.06 0.11 0.08 0 0 0.09 0.14 0.12 0.1
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 0 0
Vac/Vac Membrane 0.06 0.07 0.06 0 0.07 0 0.06 0 – 0 0 0 0.15 0.22 0.26 0.16 0.21 0.21 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 3 0 1 0 0 1 0 – 0 0 0 1 3 5 2 7 3 0 5 1 3 14 13
Bud 2 5 3 3 1 5 8 9 – 4 8 1 0 2 3 5 9 8 1 1 0 1 0 1
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1
Bud Site 0 0 0 0 0 0 2 2 – 5 2 3 0 0 0 1 5 1 – – – – – –
Cell Periphery 0 7 6 2 2 1 3 3 – 0 4 1 8 9 13 11 19 21 0 0 0 0 0 1
Cytoplasm 0 4 6 3 6 4 5 4 – 0 1 2 0 3 7 31 42 29 0 1 0 0 0 0
Endoplasmic Reticulum 0 5 2 0 0 1 0 0 – 0 0 0 2 2 4 9 9 8 0 0 0 0 2 1
Endosome 5 0 3 3 8 2 3 9 – 3 0 0 9 10 9 4 16 10 9 22 9 8 20 20
Golgi 0 2 4 1 5 0 1 0 – 0 0 0 59 94 136 12 39 24 4 17 11 11 22 34
Mitochondria 112 260 190 134 133 196 242 355 – 321 234 262 172 156 152 12 13 9 127 219 164 194 303 329
Nucleus 3 6 0 1 0 1 1 4 – 2 0 1 0 4 0 3 8 2 0 0 0 0 0 0
Nuclear Periphery 2 7 18 3 10 19 18 46 – 40 26 39 15 5 9 9 19 20 4 3 1 4 2 5
Nucleolus 26 7 10 1 7 22 29 49 – 45 25 26 7 4 4 1 8 8 2 0 0 2 1 1
Peroxisomes 1 8 1 4 9 1 7 8 – 5 5 4 9 7 7 7 25 14 6 12 18 38 50 47
SpindlePole 2 3 1 2 2 3 4 7 – 3 7 3 5 3 7 6 7 9 1 2 0 2 1 1
Vac/Vac Membrane 8 20 12 6 11 8 16 12 – 6 8 5 33 51 73 20 46 37 2 11 2 1 6 8
Unique Cell Count 126 279 213 140 156 213 266 399 345 248 275 214 237 285 122 223 174 164 302 215 272 429 471
Labelled Cell Count 162 337 256 164 194 263 340 508 434 320 347 320 353 429 133 272 203 164 302 215 272 429 471


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.5 7.1 7.3 7.3 8.6 7.5 7.3 7.2 – 6.3 6.3 6.3 10.0 9.9 9.8 6.5 7.7 8.7 9.4 9.5 10.3
Std Deviation (1e-4) 1.2 1.7 1.4 1.4 3.3 1.8 1.9 1.6 – 1.7 1.7 1.8 1.6 2.1 1.5 1.3 1.7 2.0 1.8 1.8 2.3
Intensity Change (Log2) – – – -0.01 0.23 0.04 0.0 -0.03 – -0.21 -0.21 -0.22 0.45 0.44 0.43 -0.17 0.08 0.24 0.36 0.38 0.49

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 – 0 1.3 0 0 0 0 0 1.7 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0.5 0.6 1.0 2.5 2.6 3.6
Cytoplasm 0 0.6 -0.6 0 0 – 0 0 0 0 0 -0.2 6.3 5.3 4.7
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 2.1 0
Endosome 0 0 0 0 0 – 0 0 0 1.7 1.8 1.3 0 2.9 2.4
Golgi 0 0 0 0 0 – 0 0 0 7.5 9.7 11.3 3.3 5.5 4.5
Mitochondria 2.2 -1.1 1.0 0.6 -0.1 – 1.6 2.0 2.5 -2.5 -5.9 -8.5 -14.3 -17.4 -16.5
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery -2.5 -0.7 0.2 -0.7 1.2 – 1.2 0.7 2.0 -0.6 -3.0 -2.6 -0.3 0 1.0
Nucleolus 0 -0.1 2.2 2.5 3.0 – 3.2 2.2 2.0 -0.8 -1.8 -2.2 0 -0.6 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 4.7 3.8
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole -0.6 0.6 -0.9 0.2 -1.6 – -2.5 -1.3 -2.3 3.3 4.8 5.9 3.2 4.6 4.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.0368 7.2155 7.6928 6.782 6.6648 7.2032 8.0915 7.7032 8.0219 7.8046 8.1927 8.6719 7.3819 8.7811 8.4833 7.9883 8.6726 8.2322
Actin 0.0281 0.0056 0.0165 0.0129 0.0035 0.0007 0.0212 0.0019 0.0127 0.0013 0.049 0.0012 0.0127 0.0097 0.0088 0.0051 0.003 0.021
Bud 0.0018 0.0006 0.0002 0.0007 0.0002 0 0.0004 0.0003 0.0005 0.0002 0.0004 0 0.0016 0.0027 0.0008 0.0061 0.0011 0.0003
Bud Neck 0.0009 0.0006 0.0006 0.0001 0.0001 0 0.0006 0.0002 0.0003 0.0001 0.0007 0 0.0006 0.0004 0.0002 0.0002 0.0001 0.0003
Bud Periphery 0.0036 0.0015 0.0004 0.0024 0.0003 0.0001 0.0006 0.0003 0.0008 0.0003 0.0005 0.0001 0.0034 0.0049 0.0015 0.0084 0.0047 0.0006
Bud Site 0.0023 0.008 0.0012 0.0015 0.0006 0 0.0027 0.0017 0.0026 0.0001 0.003 0 0.0028 0.0229 0.0024 0.0033 0.0004 0.0006
Cell Periphery 0.0015 0.0014 0.0003 0.0018 0.0001 0.0001 0.0002 0.0003 0.0002 0.0001 0.0003 0.0001 0.0003 0.0009 0.001 0.0004 0.0006 0.0002
Cytoplasm 0.002 0.0002 0.0003 0.0055 0.0053 0 0.0026 0.0006 0.0009 0.0001 0.0012 0 0.0026 0.0002 0.0001 0.0001 0.0001 0.0001
Cytoplasmic Foci 0.0201 0.003 0.0024 0.0039 0.0148 0.0003 0.0209 0.0106 0.008 0.0177 0.0248 0.005 0.0269 0.0083 0.003 0.009 0.002 0.0056
Eisosomes 0.0014 0.0004 0.0002 0.0012 0.0002 0.0001 0.0006 0.0001 0.0002 0.0001 0.0005 0.0001 0.0004 0.0005 0.0004 0.0002 0.0003 0.0003
Endoplasmic Reticulum 0.0021 0.0002 0.0003 0.0043 0.0016 0 0.0013 0.0002 0.001 0 0.0005 0.0001 0.0048 0.0002 0.0001 0 0.0052 0.0002
Endosome 0.034 0.0181 0.0351 0.009 0.0832 0.0013 0.0202 0.026 0.0109 0.0066 0.0418 0.0043 0.1096 0.01 0.005 0.0107 0.0148 0.0095
Golgi 0.0426 0.0284 0.0341 0.0322 0.0243 0.0039 0.0195 0.039 0.0189 0.0131 0.0396 0.0043 0.0325 0.0131 0.0051 0.0358 0.0244 0.0207
Lipid Particles 0.0381 0.0104 0.0073 0.0057 0.0432 0.0031 0.026 0.0201 0.0069 0.0259 0.0111 0.0065 0.0614 0.022 0.0091 0.0195 0.0268 0.0438
Mitochondria 0.7748 0.8978 0.8616 0.909 0.7807 0.9864 0.7494 0.8474 0.8987 0.9181 0.8033 0.9558 0.6665 0.8075 0.9083 0.8633 0.886 0.8617
None 0.0015 0.0001 0.0001 0.0016 0.0005 0 0.0279 0.0001 0.0036 0.0001 0.0003 0.0001 0.0017 0.0002 0.0001 0.0001 0.0002 0.0001
Nuclear Periphery 0.0033 0.0001 0.0002 0.0004 0.0005 0.0001 0.0075 0.0002 0.0038 0 0.0008 0.0002 0.0242 0.0017 0.0001 0 0.0019 0.0006
Nucleolus 0.0005 0.0094 0.0057 0.0001 0.0002 0.0001 0.0096 0.0003 0.0074 0.0001 0.0023 0.0001 0.0012 0.0009 0.0026 0.0008 0.0005 0.0003
Nucleus 0.0006 0.0007 0.0006 0.0002 0.0002 0.0001 0.0268 0.0002 0.0008 0 0.0018 0 0.0025 0.0007 0.0003 0.0002 0.0002 0.0001
Peroxisomes 0.015 0.0036 0.0128 0.0009 0.0325 0.0017 0.0205 0.0292 0.0159 0.0143 0.0086 0.0152 0.0183 0.0246 0.0279 0.0261 0.0048 0.0245
Punctate Nuclear 0.0087 0 0.0001 0.0002 0.0004 0 0.0362 0.0001 0.0009 0.0002 0.0036 0.0012 0.0046 0.0001 0 0.0002 0 0.0002
Vacuole 0.0095 0.0038 0.011 0.0026 0.0028 0.0003 0.0029 0.0101 0.002 0.0004 0.0041 0.0006 0.0108 0.026 0.0163 0.004 0.0078 0.0014
Vacuole Periphery 0.0077 0.0062 0.0091 0.004 0.0048 0.0018 0.0024 0.0112 0.0029 0.001 0.0016 0.005 0.0107 0.0428 0.0071 0.0063 0.0151 0.0079

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.1146 17.3414 15.4416 24.3994 19.1151 23.2657 24.0213 24.1417 29.8983 25.6597
Translational Efficiency 0.7773 0.8742 0.9241 0.7357 0.8538 0.6476 0.6741 0.7752 0.6691 0.699

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
132 1307 2493 1219 1711 834 2422 1628 1843 2141 4915 2847

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1186.74 948.37 1247.07 1149.46 865.99 929.11 1108.84 1101.95 888.96 940.87 1178.95 1122.29
Standard Deviation 177.11 166.74 201.25 176.69 135.53 140.81 176.15 165.92 161.68 157.43 201.52 172.23
Intensity Change Log 2 — -0.323482 0.071539 -0.046048 — 0.101499 0.356629 0.347636 — -0.128746 0.198741 0.133285

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.010123 0.005317 0.001112 0.005473 0.001067 0.002225 0.003597 0.007085 0.001716 0.004112 0.002337 0.006395
Bud Neck 0.005947 0.001568 0.000516 0.001560 0.000796 0.001033 0.000767 0.001085 0.001165 0.001359 0.000639 0.001288
Bud Site 0.020972 0.002766 0.000668 0.008726 0.001989 0.002142 0.002676 0.004796 0.003349 0.002523 0.001657 0.006479
Cell Periphery 0.003310 0.000199 0.000071 0.000431 0.000303 0.000149 0.000153 0.000450 0.000518 0.000179 0.000112 0.000442
Cytoplasm 0.001713 0.001134 0.000279 0.001033 0.000461 0.000283 0.000759 0.000696 0.000551 0.000802 0.000516 0.000840
Cytoplasmic Foci 0.049702 0.020506 0.017869 0.015881 0.009427 0.013106 0.010794 0.012696 0.012312 0.017623 0.014382 0.014059
Eisosomes 0.000205 0.000119 0.000045 0.000148 0.000038 0.000062 0.000075 0.000110 0.000050 0.000097 0.000060 0.000126
Endoplasmic Reticulum 0.005408 0.000162 0.000156 0.000483 0.000185 0.000110 0.000109 0.000395 0.000559 0.000142 0.000133 0.000433
Endosome 0.097473 0.024160 0.008414 0.019265 0.016802 0.017274 0.009015 0.019112 0.022580 0.021477 0.008710 0.019178
Golgi 0.186826 0.033681 0.041358 0.055717 0.011719 0.021806 0.021547 0.050077 0.024260 0.029055 0.031595 0.052492
Lipid Particles 0.000958 0.007745 0.003616 0.001137 0.004515 0.003005 0.001615 0.001364 0.004260 0.005898 0.002630 0.001267
Mitochondria 0.423629 0.858726 0.885610 0.852144 0.928539 0.908737 0.926295 0.871116 0.892376 0.878207 0.905659 0.862993
Mitotic Spindle 0.009616 0.002004 0.004297 0.006551 0.001073 0.001188 0.004013 0.003423 0.001685 0.001686 0.004157 0.004763
None 0.000346 0.000345 0.000783 0.000425 0.000196 0.000183 0.000262 0.000328 0.000207 0.000282 0.000526 0.000370
Nuclear Periphery 0.000916 0.000207 0.001089 0.000331 0.000109 0.000051 0.000120 0.000310 0.000167 0.000146 0.000611 0.000319
Nuclear Periphery Foci 0.002687 0.000496 0.000577 0.000188 0.000106 0.000121 0.000116 0.000254 0.000290 0.000350 0.000350 0.000226
Nucleolus 0.000215 0.000361 0.000118 0.000092 0.000036 0.000236 0.000060 0.000062 0.000049 0.000312 0.000089 0.000075
Nucleus 0.000244 0.000123 0.000040 0.000039 0.000026 0.000375 0.000036 0.000071 0.000041 0.000221 0.000038 0.000058
Peroxisomes 0.010866 0.035252 0.004197 0.010589 0.017505 0.022479 0.012993 0.011442 0.017030 0.030276 0.008532 0.011076
Vacuole 0.100246 0.002370 0.008160 0.009379 0.001912 0.002328 0.002157 0.006006 0.008955 0.002354 0.005202 0.007450
Vacuole Periphery 0.068598 0.002763 0.021027 0.010410 0.003196 0.003110 0.002839 0.009120 0.007880 0.002898 0.012064 0.009672

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.79 3.50 1.74 -0.16 -5.76 -2.11 -4.38 -5.38 -4.11 -2.91 -3.99 -1.51 -6.11 -2.65 -5.46
Bud Neck 2.34 2.95 2.35 -0.01 -3.52 -0.60 0.12 -0.82 -0.12 -1.01 -0.58 2.24 -0.42 0.20 -2.97
Bud Site 3.73 4.19 2.41 -3.71 -5.47 -0.14 -0.91 -2.80 -2.08 -2.01 1.04 2.60 -3.17 -4.08 -5.62
Cell Periphery 3.19 3.33 2.95 -3.42 -5.99 1.73 1.66 -1.03 -2.62 -2.56 3.08 3.74 0.59 -3.60 -4.66
Cytoplasm 0.85 4.83 2.08 0.17 -5.50 1.30 -1.21 -1.41 -3.81 0.28 -0.65 0.19 -1.94 -0.10 -2.40
Cytoplasmic Foci 4.13 4.55 4.81 2.22 1.10 -1.90 -1.02 -2.30 0.21 -1.39 -3.40 -1.60 -1.29 2.52 0.30
Eisosomes 2.49 4.85 0.95 -0.55 -2.03 -3.34 -6.38 -8.32 -4.66 -3.59 -6.05 -2.13 -3.37 -1.26 -2.95
Endoplasmic Reticulum 2.71 2.71 2.54 -4.08 -4.15 0.95 0.98 -2.39 -5.99 -6.12 2.63 2.68 0.77 -6.73 -6.98
Endosome 6.61 8.15 7.09 1.90 -6.27 -0.20 4.49 -1.06 -0.78 -6.05 0.49 7.70 1.63 1.27 -8.69
Golgi 7.41 7.05 6.27 -4.71 -3.16 -3.49 -5.27 -10.99 -6.61 -7.78 -1.75 -3.00 -8.60 -7.46 -7.23
Lipid Particles -5.19 -4.83 -0.43 5.16 5.13 1.39 3.56 3.77 2.03 0.68 -1.49 2.12 3.98 5.47 4.39
Mitochondria -13.07 -14.09 -12.84 0.65 3.84 2.28 0.39 7.48 3.92 7.61 1.82 -2.05 3.96 2.15 7.61
Mitotic Spindle 2.43 1.68 0.95 -4.76 -2.11 -0.24 -4.48 -3.54 -2.92 0.67 -0.00 -4.79 -5.10 -5.21 -0.88
None 0.00 -8.14 -1.67 -1.06 9.27 0.53 -4.09 -6.16 -5.35 -3.38 -1.61 -14.81 -8.92 -1.87 7.15
Nuclear Periphery 1.27 -0.29 1.05 -0.88 3.12 2.35 -0.30 -2.91 -3.90 -2.63 0.27 -3.62 -2.15 -2.06 2.29
Nuclear Periphery Foci 1.08 1.05 1.25 1.04 3.50 -0.32 -0.31 -2.49 -1.87 -2.18 -0.26 -0.39 0.43 0.67 1.88
Nucleolus -0.74 1.40 1.83 1.43 0.81 -1.65 -1.64 -1.03 1.41 -0.09 -2.13 -2.42 -1.44 1.91 0.66
Nucleus 1.76 3.51 3.54 2.19 0.07 -1.19 -1.08 -1.31 1.03 -0.98 -1.54 0.39 -0.79 1.38 -0.94
Peroxisomes -6.08 2.60 0.09 7.17 -4.22 -1.32 1.96 2.45 3.02 0.74 -4.58 4.49 2.88 7.50 -1.92
Vacuole 5.74 5.39 5.31 -5.50 -0.95 -0.67 -0.70 -5.22 -3.94 -4.93 4.68 2.63 0.93 -6.85 -3.00
Vacuole Periphery 6.58 4.72 5.78 -6.56 6.26 0.07 0.63 -6.60 -4.70 -7.79 4.81 -3.65 -1.60 -8.61 2.55
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Hexaprenyl pyrophosphate synthetase; catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
Localization
Cell Percentages mitochondrion (95%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Coq1

Coq1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Coq1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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Images are not yet available