Standard name
Human Ortholog
Description Succinate semialdehyde dehydrogenase; involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0.05 0 0.05 0.05 0.08 0.08 0.07 0.07 0 0 0 0 0 0.06 0 0 0 0 0 0
Cytoplasm 0.97 0.98 0.98 0.99 0.93 0.89 0.78 0.7 0.7 0.69 0.69 0.69 1.0 0.99 0.99 0.97 0.94 0.96 0.94 0.89 0.93 0.87 0.92 0.87
Endoplasmic Reticulum 0 0 0 0 0 0 0.09 0.09 0.08 0.05 0.06 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.06 0 0 0 0.05 0.07 0.08 0.06 0.16 0.13 0.15 0.18 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.08 0.15 0.08 0.13 0.14 0.11 0 0 0 0 0.08 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 1 8 8 6 3 4 0 0 0 0 0 1 0 2 2 1 2 3
Bud 0 2 0 0 3 2 2 2 2 5 2 4 0 0 0 0 0 0 1 4 2 2 2 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 6 4 3 13 15 14 19 27 27 20 25 0 3 4 5 6 12 0 0 0 0 0 0
Cytoplasm 201 360 299 160 241 314 230 284 241 243 211 238 419 365 395 187 161 186 191 334 277 132 229 180
Endoplasmic Reticulum 1 1 2 0 3 7 26 37 27 18 19 22 1 0 2 4 6 4 0 0 3 1 1 2
Endosome 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 3 1 1 0 1
Golgi 1 0 0 0 1 0 2 2 3 0 2 0 0 1 0 1 4 1 1 0 2 1 0 1
Mitochondria 12 5 4 3 12 26 23 25 56 44 47 61 0 0 0 1 0 2 3 9 3 2 4 3
Nucleus 0 2 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 2 0 2 0 1 0 0
Nuclear Periphery 0 0 0 0 0 0 1 1 2 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 1 1 1
Vac/Vac Membrane 1 6 3 1 6 7 23 60 29 46 42 38 0 2 3 5 13 1 0 4 2 1 0 1
Unique Cell Count 207 367 305 162 260 351 294 407 344 350 305 344 420 368 399 192 172 194 205 375 300 152 251 209
Labelled Cell Count 216 382 313 167 279 371 322 439 395 398 351 392 420 371 404 203 191 209 205 375 300 152 251 209


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.4 5.7 6.6 6.5 10.4 13.9 15.6 16.6 19.1 18.2 19.1 19.2 5.3 5.9 6.0 23.7 28.4 27.7 5.3 5.3 6.3
Std Deviation (1e-4) 1.0 1.7 2.8 2.2 7.5 4.8 6.2 7.0 9.6 8.9 9.7 10.2 1.1 1.5 1.5 7.8 9.2 7.8 2.1 1.4 2.0
Intensity Change (Log2) – – – -0.02 0.66 1.08 1.25 1.34 1.54 1.47 1.54 1.55 -0.32 -0.16 -0.13 1.85 2.11 2.07 -0.32 -0.32 -0.06

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 2.6 2.3 2.5 2.5 3.9 3.8 3.3 3.7 0 0 0 0 0 3.0
Cytoplasm 0.6 -3.1 -4.4 -7.5 -9.7 -9.5 -9.7 -9.6 -9.7 2.4 1.3 1.1 -0.5 -2.5 -1.4
Endoplasmic Reticulum 0 0 0 4.7 4.9 4.4 3.3 3.8 3.9 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 2.4 3.7 3.8 3.2 6.6 5.5 6.3 7.0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 4.1 6.4 4.4 5.9 6.0 5.3 0 0 0 0 3.8 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.81 2.6051 2.1516 1.9291 1.891 2.0575 3.5184 3.5088 3.671 3.2946 3.1474 3.6289 4.9156 5.8077 4.793 4.5711 4.59 4.6673
Actin 0.0395 0.0057 0.0124 0.0112 0.037 0.0267 0.0337 0.0059 0.0347 0.0612 0.0045 0.0233 0.0269 0.0021 0.0337 0.0002 0.0124 0.006
Bud 0.0013 0.006 0.0009 0.001 0.004 0.0018 0.0062 0.0003 0.0054 0.0039 0.0071 0.0017 0.0027 0.0063 0.0006 0.0005 0.0012 0.0002
Bud Neck 0.0098 0.0003 0.0014 0.0007 0.0071 0.0028 0.0024 0.0002 0.0009 0.0109 0.0003 0.006 0.0087 0.0002 0.0003 0.0001 0.0022 0.0003
Bud Periphery 0.002 0.0034 0.0017 0.001 0.02 0.0051 0.0055 0.0003 0.0067 0.0056 0.0065 0.0036 0.003 0.0033 0.0009 0.0006 0.0026 0.0004
Bud Site 0.011 0.0045 0.0038 0.0014 0.0014 0.0013 0.0173 0.0026 0.0079 0.0155 0.0008 0.0007 0.0081 0.0026 0.0008 0.0001 0.0064 0.0001
Cell Periphery 0.0006 0.0005 0.0006 0.0002 0.0003 0.0002 0.0007 0.0003 0.0004 0.0004 0.0001 0.0001 0.0004 0.0006 0.0002 0 0.0003 0.0001
Cytoplasm 0.4684 0.7051 0.5761 0.5875 0.567 0.6435 0.399 0.4943 0.4076 0.4547 0.4883 0.4592 0.4948 0.5526 0.5329 0.7374 0.4763 0.6092
Cytoplasmic Foci 0.0188 0.009 0.0158 0.0269 0.0172 0.0289 0.0429 0.0196 0.0307 0.0146 0.0072 0.0215 0.0633 0.0058 0.0207 0.0064 0.0149 0.0061
Eisosomes 0.0009 0.0001 0.0003 0.0003 0.0003 0.0003 0.0003 0.0004 0.0002 0.0003 0.0001 0.0002 0.0002 0.0001 0.0002 0 0.0001 0.0001
Endoplasmic Reticulum 0.0073 0.004 0.0053 0.0061 0.0045 0.0039 0.0155 0.0027 0.0049 0.0038 0.0011 0.0016 0.0055 0.0025 0.0092 0.0008 0.0108 0.0083
Endosome 0.0241 0.004 0.0201 0.0322 0.0199 0.0167 0.0314 0.0132 0.018 0.006 0.0053 0.0077 0.039 0.0006 0.0124 0.0012 0.062 0.0118
Golgi 0.0124 0.0003 0.0093 0.0116 0.0077 0.0198 0.014 0.0015 0.0123 0.0096 0.0057 0.0041 0.0229 0.0003 0.0062 0.0001 0.0099 0.0024
Lipid Particles 0.0139 0.0003 0.0093 0.0077 0.0191 0.0143 0.0134 0.0018 0.0092 0.0007 0.0053 0.0032 0.0318 0.0001 0.0121 0 0.0078 0.001
Mitochondria 0.0184 0.0004 0.0086 0.0165 0.0031 0.0215 0.0051 0.0004 0.0071 0.0242 0.0109 0.0047 0.0226 0.0003 0.0061 0.0002 0.0127 0.0032
None 0.3328 0.2466 0.3101 0.2737 0.2699 0.186 0.3589 0.4495 0.4096 0.3775 0.446 0.4469 0.19 0.4179 0.3444 0.2496 0.3166 0.345
Nuclear Periphery 0.0078 0.0016 0.0049 0.0032 0.0033 0.0017 0.0136 0.0007 0.0066 0.0018 0.0005 0.0008 0.0079 0.0006 0.0016 0.0003 0.0255 0.003
Nucleolus 0.0023 0.0001 0.0004 0.0003 0.0004 0.0001 0.0011 0.0002 0.0005 0.0001 0.0001 0.0001 0.0009 0.0001 0.0001 0 0.0009 0
Nucleus 0.006 0.003 0.0041 0.0023 0.0022 0.0051 0.0041 0.0009 0.003 0.0023 0.001 0.0017 0.0028 0.0011 0.0014 0.0011 0.0061 0.001
Peroxisomes 0.012 0.0008 0.009 0.0087 0.0073 0.0166 0.0198 0.0019 0.0239 0.0043 0.0073 0.0098 0.023 0.0016 0.0094 0.0001 0.0032 0.0001
Punctate Nuclear 0.0054 0.001 0.0012 0.0033 0.006 0.0016 0.0059 0.0021 0.0078 0.0014 0.0005 0.0025 0.04 0.0003 0.0051 0.0003 0.0089 0.0004
Vacuole 0.0039 0.0028 0.0038 0.0034 0.0016 0.0016 0.0062 0.0012 0.0019 0.0008 0.0011 0.0005 0.0032 0.0009 0.0011 0.0007 0.0098 0.0008
Vacuole Periphery 0.0015 0.0004 0.0009 0.0009 0.0006 0.0005 0.0031 0.0002 0.0008 0.0003 0.0003 0.0002 0.0021 0.0001 0.0004 0.0001 0.0093 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.9705 5.2818 6.8588 8.3605 6.703 8.1196 8.0106 10.1374 12.112 10.4446
Translational Efficiency 1.2545 1.0137 1.2949 1.4444 1.198 2.1047 1.1533 0.9404 1.1666 1.0309

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2203 1458 1449 1404 860 2049 802 818 3063 3507 2251 2222

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 671.03 716.77 883.94 907.77 740.37 675.00 1142.12 881.45 690.50 692.37 975.93 898.08
Standard Deviation 86.73 98.05 127.18 209.02 169.09 103.02 212.69 194.60 120.04 103.06 204.49 204.22
Intensity Change Log 2 — 0.095133 0.397571 0.435950 — -0.133359 0.625396 0.251632 — -0.020206 0.521550 0.342204

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000205 0.000336 0.000167 0.001190 0.000090 0.000538 0.000210 0.000876 0.000173 0.000454 0.000182 0.001074
Bud Neck 0.015004 0.033776 0.002145 0.006734 0.002068 0.041512 0.001049 0.003976 0.011372 0.038296 0.001755 0.005719
Bud Site 0.008243 0.018029 0.010060 0.029891 0.003770 0.023640 0.009618 0.034897 0.006987 0.021307 0.009903 0.031734
Cell Periphery 0.000191 0.000124 0.000101 0.000125 0.000115 0.000110 0.000084 0.000235 0.000169 0.000116 0.000095 0.000165
Cytoplasm 0.605712 0.429424 0.646352 0.593419 0.704645 0.434406 0.752665 0.597765 0.633489 0.432335 0.684230 0.595019
Cytoplasmic Foci 0.174591 0.254136 0.014683 0.026815 0.093526 0.254707 0.022764 0.023730 0.151831 0.254470 0.017562 0.025680
Eisosomes 0.000140 0.000110 0.000022 0.000029 0.000041 0.000113 0.000019 0.000053 0.000112 0.000112 0.000021 0.000038
Endoplasmic Reticulum 0.001059 0.001119 0.001530 0.001216 0.000539 0.000521 0.000957 0.000935 0.000913 0.000770 0.001326 0.001112
Endosome 0.006644 0.030004 0.002182 0.007233 0.002813 0.033266 0.003093 0.003703 0.005568 0.031910 0.002507 0.005933
Golgi 0.002645 0.006090 0.000141 0.006106 0.000390 0.006859 0.000637 0.000490 0.002012 0.006539 0.000318 0.004039
Lipid Particles 0.004436 0.006199 0.000918 0.000872 0.001706 0.006063 0.000977 0.001036 0.003669 0.006120 0.000939 0.000932
Mitochondria 0.003054 0.009585 0.000336 0.001610 0.000294 0.014216 0.000100 0.000884 0.002279 0.012290 0.000252 0.001343
Mitotic Spindle 0.000597 0.004519 0.003117 0.052604 0.000410 0.006870 0.004957 0.025266 0.000544 0.005893 0.003773 0.042540
None 0.007411 0.003325 0.004875 0.005321 0.007843 0.003512 0.003752 0.005824 0.007532 0.003435 0.004475 0.005506
Nuclear Periphery 0.000209 0.000425 0.000735 0.000836 0.000241 0.000284 0.001544 0.000603 0.000218 0.000343 0.001023 0.000750
Nuclear Periphery Foci 0.000275 0.000570 0.002191 0.001465 0.000844 0.000290 0.004240 0.000987 0.000435 0.000406 0.002921 0.001289
Nucleolus 0.001228 0.002187 0.000348 0.000261 0.000432 0.001532 0.000122 0.000396 0.001004 0.001804 0.000267 0.000311
Nucleus 0.126425 0.085291 0.259546 0.150654 0.155948 0.061549 0.079326 0.172580 0.134714 0.071419 0.195336 0.158726
Peroxisomes 0.001941 0.013112 0.000188 0.005538 0.000637 0.014092 0.000219 0.001678 0.001575 0.013684 0.000199 0.004117
Vacuole 0.038795 0.097862 0.050116 0.106122 0.023347 0.093185 0.113456 0.123440 0.034457 0.095129 0.072683 0.112497
Vacuole Periphery 0.001197 0.003777 0.000246 0.001960 0.000299 0.002734 0.000211 0.000644 0.000945 0.003168 0.000233 0.001475

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.34 -0.06 -2.41 -1.88 -3.09 -3.36 -4.04 -3.29 0.02 -2.25 -2.72 -0.64 -3.44 -0.79 -3.82
Bud Neck -8.00 12.73 9.22 13.13 -4.41 -18.54 1.41 -2.47 18.02 -5.21 -16.07 12.86 8.92 21.85 -5.77
Bud Site -6.48 -0.32 -3.86 1.67 -2.58 -12.01 -2.82 -5.03 1.85 -3.10 -12.34 -1.28 -5.98 3.17 -3.93
Cell Periphery 6.15 8.21 9.92 3.87 1.23 0.59 3.55 -1.06 -1.34 -2.70 5.79 9.24 5.97 0.55 -1.53
Cytoplasm 19.81 1.19 13.10 -5.54 10.60 26.71 3.41 13.97 -7.07 9.95 31.03 1.99 17.83 -8.66 14.35
Cytoplasmic Foci -11.53 41.73 40.48 40.16 -1.67 -24.75 15.70 16.99 46.15 2.40 -21.33 43.18 42.98 61.37 0.15
Eisosomes 4.08 17.10 16.06 20.84 -4.22 -15.54 6.88 -0.60 14.90 -7.38 0.19 17.89 15.18 25.13 -8.01
Endoplasmic Reticulum -0.26 -5.85 -2.25 -1.69 4.51 0.29 -3.69 -5.35 -6.08 -1.54 1.36 -6.20 -3.69 -5.87 3.40
Endosome -14.18 9.25 6.74 16.61 -0.69 -17.84 0.32 1.66 18.11 1.15 -21.43 8.71 7.31 24.06 -0.05
Golgi -5.37 10.34 1.76 5.33 -2.18 -13.78 0.06 1.64 14.05 0.64 -11.09 9.44 2.30 10.19 -2.02
Lipid Particles -3.06 10.62 10.59 10.08 -0.96 -8.28 2.88 3.16 9.73 -0.35 -5.81 10.93 10.98 13.80 -0.96
Mitochondria -5.51 7.52 6.02 7.79 -2.48 -10.98 5.90 -1.45 10.77 -3.07 -10.93 7.82 5.91 13.17 -3.45
Mitotic Spindle -4.13 -3.36 -9.05 -7.53 -7.94 -5.84 -3.62 -5.16 -2.58 -3.20 -7.04 -4.85 -10.36 -7.66 -8.52
None 4.59 4.15 2.38 -3.40 -2.84 4.28 5.88 2.23 -2.57 -4.29 5.75 6.30 3.05 -4.01 -4.93
Nuclear Periphery -4.79 -20.66 -21.57 -15.01 -8.62 -0.85 -1.54 -13.83 -11.08 0.12 -3.88 -3.98 -25.44 -19.17 -1.77
Nuclear Periphery Foci -4.40 -11.09 -11.00 -7.29 5.57 3.37 -9.43 -2.94 -8.29 8.20 0.42 -14.86 -10.76 -11.44 9.56
Nucleolus -2.24 4.85 5.20 4.74 0.46 -5.70 9.63 2.08 6.15 -5.09 -3.49 5.60 5.35 7.47 -1.33
Nucleus 9.76 -22.36 -9.08 -15.40 11.98 15.39 10.35 -1.03 -14.46 -10.30 20.15 -13.91 -8.17 -22.63 5.37
Peroxisomes -12.16 5.61 0.45 10.53 -2.10 -14.56 2.39 -0.37 14.32 -2.47 -17.83 6.00 0.59 16.07 -2.54
Vacuole -16.44 -10.84 -29.05 -18.81 -20.71 -21.33 -20.85 -22.75 -15.00 -3.31 -25.41 -21.62 -36.66 -24.53 -17.48
Vacuole Periphery -5.22 10.07 3.01 6.17 -1.44 -13.87 3.39 0.14 12.75 -1.47 -9.48 10.69 3.43 10.39 -1.74
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Succinate semialdehyde dehydrogenase; involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm
Localization
Cell Percentages cytoplasm (80%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Uga2

Uga2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Uga2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available