Standard name
Human Ortholog
Description Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.05 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0
Bud 0.06 0 0 0 0 0 0 – 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.05 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0.05 0 0 0.09 0.12 0.15 0 0 0 0 0 0
Cytoplasm 0.9 0.92 0.97 0.97 0.96 0.94 0.91 – 0.82 0.82 0.8 0.85 0.96 0.96 0.96 0.96 0.95 0.94 0.88 0.83 0.85 0.62 0.65 0.76
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.07 0.09 – 0.25 0.23 0.23 0.17 0 0 0 0 0 0 0 0 0 0.08 0.06 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 6 4 8 6 11 3 7 – 3 5 4 2 7 10 4 1 2 2 2 5 7 16 31 21
Bud 7 8 5 6 10 6 15 – 14 26 17 16 12 9 16 5 2 4 2 10 8 11 18 20
Bud Neck 0 1 7 2 3 6 3 – 4 0 3 1 0 0 1 0 0 0 3 5 7 23 22 18
Bud Site 1 1 1 0 0 0 1 – 3 0 4 1 0 2 1 0 0 0 – – – – – –
Cell Periphery 1 1 13 9 17 16 9 – 12 15 13 16 17 6 19 28 25 34 0 0 3 4 11 10
Cytoplasm 108 197 354 324 472 455 615 – 424 549 284 505 343 492 640 296 198 207 108 196 316 187 313 465
Endoplasmic Reticulum 1 5 0 0 1 2 5 – 1 3 4 3 1 2 2 15 4 13 0 1 3 4 14 8
Endosome 0 0 0 1 0 0 1 – 0 3 0 0 2 0 1 0 0 0 0 1 2 3 3 4
Golgi 0 1 0 0 0 0 0 – 0 0 0 0 0 0 0 0 1 1 0 0 0 0 1 0
Mitochondria 4 7 1 1 3 33 60 – 127 156 82 100 4 2 7 3 3 1 0 7 11 22 30 18
Nucleus 0 0 1 3 2 1 2 – 4 4 3 4 0 0 1 3 4 0 0 0 1 0 0 0
Nuclear Periphery 0 1 0 1 0 0 0 – 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 1 0 0 0 0 0 – 1 1 0 0 0 4 3 0 0 0 0 0 0 1 0 0
SpindlePole 0 0 1 4 1 4 6 – 1 6 1 7 1 5 1 0 1 1 0 0 1 0 1 5
Vac/Vac Membrane 0 0 3 0 2 2 4 – 3 9 1 5 1 0 1 3 2 3 0 2 5 21 25 25
Unique Cell Count 120 213 365 334 492 486 679 514 667 354 594 358 510 665 308 209 221 123 237 373 300 481 610
Labelled Cell Count 128 227 394 357 522 528 728 597 779 416 661 388 533 697 354 242 266 123 237 373 300 481 610


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.9 5.0 5.9 5.5 6.2 4.9 4.9 – 4.2 4.3 4.2 4.7 5.2 5.0 5.2 7.5 7.8 7.7 4.8 4.7 5.4
Std Deviation (1e-4) 0.6 0.7 1.1 1.6 1.5 1.0 0.8 – 0.6 0.8 0.8 0.8 0.8 0.7 1.0 1.0 1.0 1.1 1.1 0.9 1.2
Intensity Change (Log2) – – – -0.09 0.08 -0.25 -0.27 – -0.48 -0.46 -0.47 -0.33 -0.18 -0.23 -0.17 0.36 0.4 0.39 -0.29 -0.32 -0.13

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.4 0 0 -1.5 – 0 0 0 0 -0.2 -0.2 0 0 0 0
Bud 0.5 0.7 0 0.9 – 0 0 0 0 1.8 0.5 1.1 0 0 0
Bud Neck 0 0 -0.8 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.7 -0.1 -0.2 -2.4 – 0 0 0 0 0.8 -2.4 -0.6 3.0 3.9 5.1
Cytoplasm 0 -0.8 -2.2 -3.8 – -6.6 -6.8 -7.1 -5.9 -0.8 -0.4 -0.6 -0.6 -1.4 -1.9
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 4.3 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.8 5.6 – 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.4691 0.6975 0.5535 0.731 0.1471 0.4358 -0.1114 -0.0812 0.3884 0.6774 0.2542 0.3555 0.2097 0.3632 0.397 0.5981 0.7109 0.3316
Actin 0.1129 0.0017 0.0074 0.0206 0.017 0.0046 0.0098 0.0019 0.0166 0.0018 0.0029 0.0204 0.0135 0.0078 0.0453 0.0231 0.009 0.0048
Bud 0.0079 0.0096 0.0127 0.0021 0.0006 0.003 0.0012 0.0055 0.0039 0.0046 0.0019 0.001 0.0118 0.0021 0.0553 0.0003 0.0019 0.0001
Bud Neck 0.0026 0.0009 0.0319 0.0006 0.0005 0.0303 0.0014 0.0015 0.0022 0.0009 0.0007 0.0464 0.0009 0.0012 0.0042 0.0008 0.0246 0.0308
Bud Periphery 0.0183 0.0148 0.0219 0.0084 0.0007 0.0047 0.0019 0.0095 0.0048 0.0079 0.0027 0.0014 0.0124 0.0019 0.0606 0.0002 0.0031 0.0001
Bud Site 0.0154 0.0219 0.028 0.0013 0.0012 0.0014 0.0097 0.0294 0.0128 0.002 0.0019 0.0009 0.0203 0.0331 0.03 0.0007 0.0121 0.0001
Cell Periphery 0.0022 0.0011 0.0011 0.0004 0.0002 0.0006 0.0006 0.001 0.0005 0.0004 0.0001 0.0003 0.0005 0.001 0.001 0.0001 0.0008 0.0002
Cytoplasm 0.2705 0.4012 0.3838 0.5402 0.4893 0.461 0.59 0.4977 0.649 0.6209 0.6165 0.7128 0.5049 0.5869 0.532 0.6523 0.6595 0.7805
Cytoplasmic Foci 0.0253 0.0184 0.0147 0.0173 0.0177 0.017 0.048 0.0307 0.0236 0.0307 0.0372 0.0144 0.0179 0.0147 0.0175 0.032 0.0225 0.0053
Eisosomes 0.0007 0.0002 0.0007 0.0006 0.0001 0.0001 0.0004 0.0003 0.0002 0.0001 0 0.0001 0.0004 0.0005 0.0005 0.0002 0.0002 0.0001
Endoplasmic Reticulum 0.0058 0.002 0.0076 0.005 0.0025 0.0033 0.0034 0.0013 0.0026 0.0026 0.0018 0.0023 0.0144 0.0034 0.0045 0.0023 0.0028 0.0045
Endosome 0.0403 0.0053 0.0074 0.0128 0.0106 0.0112 0.0213 0.0024 0.0249 0.0264 0.0909 0.0094 0.0373 0.0045 0.0189 0.0439 0.0546 0.0044
Golgi 0.0147 0.0006 0.0011 0.0027 0.0027 0.005 0.007 0.001 0.0071 0.0114 0.0265 0.0029 0.0043 0.0016 0.005 0.0132 0.0168 0.0005
Lipid Particles 0.0115 0.001 0.004 0.0036 0.002 0.0019 0.0131 0.001 0.0014 0.0089 0.0012 0.0007 0.0085 0.001 0.0037 0.0206 0.021 0.0005
Mitochondria 0.0052 0.0006 0.0035 0.0033 0.0012 0.0026 0.0139 0.0008 0.0074 0.0186 0.0129 0.0123 0.016 0.001 0.0127 0.0025 0.0096 0.0005
None 0.4301 0.5131 0.4487 0.3561 0.4266 0.44 0.235 0.4073 0.2329 0.2445 0.1878 0.1604 0.2557 0.3323 0.1902 0.1781 0.1071 0.1598
Nuclear Periphery 0.0038 0.0006 0.0046 0.0058 0.0049 0.0021 0.0026 0.0004 0.0007 0.0011 0.0009 0.006 0.0371 0.0007 0.0012 0.0023 0.005 0.0035
Nucleolus 0.0004 0.0007 0.002 0.0007 0.0002 0.0003 0.0009 0.0004 0.0003 0.0003 0.0001 0.0001 0.0023 0.0003 0.0003 0.0004 0.0022 0.0002
Nucleus 0.0017 0.0012 0.0056 0.0022 0.0016 0.0022 0.0034 0.0012 0.0012 0.002 0.0013 0.0018 0.0185 0.0014 0.0012 0.001 0.0046 0.0018
Peroxisomes 0.0116 0.0005 0.0033 0.0082 0.0032 0.0007 0.0249 0.0032 0.0024 0.005 0.0021 0.0037 0.0075 0.0015 0.0042 0.0075 0.0121 0.0001
Punctate Nuclear 0.0096 0.0013 0.0023 0.0058 0.015 0.0044 0.0057 0.0018 0.0008 0.0011 0.0005 0.0007 0.0049 0.0009 0.0012 0.0069 0.0014 0.0009
Vacuole 0.0083 0.0029 0.0062 0.0019 0.002 0.003 0.0045 0.0016 0.0042 0.0069 0.0075 0.0015 0.0075 0.002 0.0087 0.0078 0.0231 0.0009
Vacuole Periphery 0.0011 0.0003 0.0013 0.0005 0.0004 0.0007 0.0012 0.0001 0.0008 0.0019 0.0026 0.0007 0.0034 0.0002 0.0019 0.0035 0.0058 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 15.9697 5.3535 6.6208 8.6084 13.9114 14.4645 9.6981 8.9811 9.0583 15.6539
Translational Efficiency 0.8096 1.8738 0.7804 0.7266 0.781 0.8974 0.9876 0.8753 0.8303 0.8526

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1029 1465 2003 1115 1017 1154 2659 631 2046 2619 4662 1746

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 562.34 672.52 743.61 875.60 555.16 692.43 843.68 627.09 558.77 681.29 800.69 785.79
Standard Deviation 93.51 124.21 175.17 104.19 92.54 139.53 93.24 219.30 93.10 131.56 143.51 196.38
Intensity Change Log 2 — 0.258135 0.403104 0.638829 — 0.318765 0.603792 0.175769 — 0.288573 0.506291 0.427273

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000217 0.000505 0.000514 0.002134 0.000339 0.000802 0.000802 0.000337 0.000278 0.000636 0.000678 0.001484
Bud Neck 0.033913 0.020994 0.016738 0.008882 0.051300 0.040808 0.017579 0.041409 0.042556 0.029724 0.017218 0.020638
Bud Site 0.027146 0.030618 0.044322 0.069110 0.027372 0.041674 0.056559 0.040313 0.027259 0.035490 0.051301 0.058703
Cell Periphery 0.000537 0.000195 0.000170 0.000270 0.000361 0.000362 0.000116 0.004352 0.000450 0.000269 0.000139 0.001745
Cytoplasm 0.521066 0.579460 0.696469 0.559286 0.478958 0.520915 0.693592 0.598840 0.500136 0.553664 0.694828 0.573581
Cytoplasmic Foci 0.179040 0.156979 0.032009 0.033524 0.226015 0.171652 0.024213 0.069065 0.202390 0.163445 0.027562 0.046368
Eisosomes 0.000656 0.000172 0.000043 0.000089 0.000621 0.000355 0.000045 0.004520 0.000639 0.000252 0.000044 0.001691
Endoplasmic Reticulum 0.002209 0.000888 0.000771 0.001982 0.001171 0.000566 0.000426 0.000454 0.001693 0.000746 0.000575 0.001430
Endosome 0.016532 0.016822 0.002655 0.003197 0.027497 0.025020 0.001607 0.005088 0.021982 0.020434 0.002057 0.003881
Golgi 0.003645 0.002253 0.000342 0.001079 0.004945 0.004737 0.000163 0.003679 0.004291 0.003347 0.000240 0.002019
Lipid Particles 0.011280 0.005090 0.001142 0.001048 0.013259 0.008299 0.000411 0.004880 0.012263 0.006504 0.000725 0.002433
Mitochondria 0.002594 0.002033 0.000830 0.004063 0.004272 0.004853 0.000484 0.000489 0.003428 0.003275 0.000633 0.002771
Mitotic Spindle 0.000288 0.000580 0.006340 0.013313 0.000862 0.004276 0.009668 0.001202 0.000573 0.002208 0.008238 0.008936
None 0.019201 0.007043 0.010767 0.004407 0.013594 0.017789 0.001314 0.056428 0.016414 0.011778 0.005376 0.023207
Nuclear Periphery 0.000840 0.000458 0.000380 0.000483 0.000332 0.000242 0.000200 0.000194 0.000587 0.000363 0.000277 0.000379
Nuclear Periphery Foci 0.001238 0.000699 0.001029 0.001728 0.000518 0.000397 0.000379 0.003695 0.000880 0.000566 0.000658 0.002439
Nucleolus 0.001794 0.001645 0.000863 0.000126 0.001572 0.001912 0.000111 0.001224 0.001684 0.001763 0.000434 0.000523
Nucleus 0.090947 0.070105 0.115474 0.088455 0.058390 0.058724 0.070772 0.063987 0.074764 0.065090 0.089978 0.079612
Peroxisomes 0.003078 0.004426 0.001418 0.001410 0.005236 0.009840 0.001526 0.003331 0.004151 0.006811 0.001480 0.002104
Vacuole 0.082599 0.097512 0.066875 0.203261 0.081972 0.085373 0.119872 0.096259 0.082288 0.092163 0.097102 0.164591
Vacuole Periphery 0.001179 0.001522 0.000849 0.002154 0.001414 0.001404 0.000160 0.000252 0.001296 0.001470 0.000456 0.001467

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.38 -5.83 -5.47 -3.76 -3.66 -2.93 -4.45 0.48 3.06 4.42 -3.67 -7.00 -5.14 -2.34 -2.34
Bud Neck 3.81 6.21 9.09 8.16 4.96 2.13 8.77 3.67 2.11 -4.77 4.33 10.74 9.44 7.02 -0.77
Bud Site -0.77 -1.99 -1.85 -1.33 -0.03 -2.96 -3.28 -0.94 1.76 1.77 -2.59 -3.82 -2.10 0.27 1.26
Cell Periphery 5.66 7.28 6.17 -0.17 -2.21 0.05 10.59 -5.32 -5.30 -5.84 4.29 11.21 -4.18 -5.12 -5.95
Cytoplasm -5.37 -12.29 4.93 10.22 16.98 -3.54 -17.07 -8.39 -5.37 3.90 -6.65 -20.79 -1.33 4.54 16.39
Cytoplasmic Foci 3.45 28.50 29.14 28.92 1.55 6.94 33.76 23.60 17.54 -8.50 7.69 44.02 38.40 33.68 -6.52
Eisosomes 5.81 8.43 7.90 1.99 -8.63 3.29 7.88 -4.05 -4.49 -4.97 6.60 11.54 -2.45 -4.12 -5.01
Endoplasmic Reticulum 3.60 3.02 0.58 -5.07 -4.82 1.91 2.14 2.59 1.53 2.23 3.87 3.90 1.14 -4.69 -5.57
Endosome -0.12 14.79 15.26 15.07 2.02 1.01 15.48 13.61 10.67 -6.69 1.19 20.73 19.63 17.27 -3.80
Golgi 3.22 8.60 7.80 7.33 -0.82 0.27 9.98 1.46 1.24 -1.70 2.12 13.20 4.90 3.29 -1.87
Lipid Particles 5.67 10.79 10.63 6.41 -1.55 2.73 9.44 6.74 3.51 -5.97 5.57 13.97 12.00 6.48 -6.93
Mitochondria 1.08 3.77 1.26 0.68 -0.87 -0.44 4.60 4.62 4.43 0.36 0.25 5.95 3.40 3.19 -0.98
Mitotic Spindle -1.72 -6.65 -4.64 -4.44 -0.27 -2.15 -5.81 -1.12 1.62 5.47 -2.26 -8.39 -4.54 -2.62 2.33
None 4.07 3.88 5.81 2.76 4.11 -0.89 5.12 -4.23 -3.41 -6.61 1.98 6.56 0.01 -1.72 -5.26
Nuclear Periphery 0.80 0.53 0.18 -2.65 -2.81 1.47 -0.39 0.85 -0.88 1.97 0.93 0.56 0.00 -3.26 -3.54
Nuclear Periphery Foci 3.72 0.81 -3.06 -8.13 -4.52 1.01 1.20 -3.16 -3.34 -3.35 3.36 1.90 -4.55 -5.90 -5.37
Nucleolus 0.53 5.00 9.99 5.97 3.05 -0.61 4.91 2.08 2.09 -5.57 -0.25 7.31 7.06 5.23 -0.84
Nucleus 4.05 -9.01 -3.79 -8.24 5.28 -0.04 -7.06 -1.55 -1.59 4.45 2.90 -10.39 -5.34 -8.35 3.96
Peroxisomes -2.50 5.19 7.16 8.10 2.41 -3.48 7.88 1.83 3.92 -0.97 -4.01 9.44 4.75 6.94 -0.29
Vacuole -3.71 -5.85 -27.40 -25.44 -23.85 -1.13 -17.33 -7.74 -7.11 2.86 -3.68 -17.33 -26.67 -24.79 -16.72
Vacuole Periphery -2.16 1.56 1.59 2.63 -0.27 0.10 13.17 11.50 6.62 -1.34 -1.32 5.74 4.09 4.57 -0.87
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress
Localization
Cell Percentages cytoplasm (81%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Dsf2

Dsf2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dsf2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available