Standard name
Human Ortholog
Description Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin; relocalizes from nucleus to plasma membrane upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.97 0.92 0.98 0.97 0.96 0.88 0.85 0.86 – 0.76 0.67 0.69 1.0 1.0 0.99 – – – 0.84 0.72 0.67 0.75 0.79 0.72
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0.1 0 0 0 0.25 0.22 0.25 – 0.46 0.53 0.46 0 0 0 – – – 0.07 0.1 0.16 0.14 0.1 0.1
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 1 6 6 3 4 7
Bud 0 1 1 1 0 1 4 7 – 8 11 17 0 2 0 – – – 0 1 4 3 5 14
Bud Neck 2 1 1 2 3 4 5 11 – 6 1 4 0 1 0 – – – 0 1 4 2 4 6
Bud Site 0 0 0 0 0 0 0 0 – 2 2 2 0 0 0 – – – – – – – – –
Cell Periphery 1 2 3 3 3 0 2 0 – 2 3 1 7 10 0 – – – 1 0 5 4 7 8
Cytoplasm 192 141 299 240 287 290 387 453 – 349 267 296 152 296 347 – – – 172 117 195 248 406 378
Endoplasmic Reticulum 4 2 1 0 0 0 0 0 – 0 0 1 0 0 2 – – – 0 0 5 3 3 3
Endosome 0 0 1 0 2 0 2 1 – 1 0 2 0 0 1 – – – 3 3 2 2 2 5
Golgi 1 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 1 2 1 3
Mitochondria 1 15 7 8 10 84 99 132 – 213 209 199 0 0 0 – – – 14 16 46 45 52 54
Nucleus 0 0 0 1 2 1 2 2 – 3 1 2 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 1 1 0 0 0 1 0 0 – 1 0 0 0 0 0 – – – 0 1 1 0 0 1
Nucleolus 0 0 0 0 1 0 0 0 – 1 2 1 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 1 0 0 0 – 0 0 0 0 0 0 – – – 1 0 0 0 0 0
SpindlePole 0 0 0 2 1 2 9 9 – 13 8 19 0 0 0 – – – 2 2 5 3 7 13
Vac/Vac Membrane 0 0 1 0 2 0 4 0 – 5 2 0 0 0 2 – – – 1 4 2 5 8 12
Unique Cell Count 197 154 306 247 299 331 455 525 459 396 428 152 297 351 204 163 292 333 514 524
Labelled Cell Count 202 163 314 257 312 383 514 615 604 506 544 159 309 352 204 163 292 333 514 524


Cell Periphery, Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.5 3.6 3.1 3.0 3.2 2.5 2.5 2.8 – 2.2 2.3 2.3 4.6 4.8 5.1 3.2 3.7 4.4 4.8 4.8 5.1
Std Deviation (1e-4) 0.5 1.0 0.7 0.9 1.5 0.9 1.1 1.3 – 0.8 0.7 0.9 0.7 0.8 1.6 0.7 0.9 2.0 1.4 1.0 1.6
Intensity Change (Log2) – – – -0.04 0.08 -0.27 -0.27 -0.13 – -0.46 -0.41 -0.39 0.6 0.64 0.75 0.06 0.26 0.54 0.64 0.64 0.74

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.0043 0.317 0.3176 0.1043 0.287 0.1805 -0.7618 -0.3437 -0.5884 -0.4018 -0.4121 -0.4913 -1.3191 -0.6785 -1.1222 -0.8551 -1.4852 -0.986
Actin 0.032 0.0003 0.0256 0.0228 0.0182 0.0081 0.0202 0 0.0011 0.0009 0.0051 0.0029 0.0158 0.0002 0.0002 0.0003 0 0.0003
Bud 0.0021 0.0011 0.0051 0.0228 0.0005 0.0017 0.0023 0 0.0041 0.0002 0.0058 0.0015 0.0002 0.0003 0.0005 0.0018 0 0.0001
Bud Neck 0.0048 0.0002 0.0026 0.009 0.0035 0.0023 0.0009 0 0.0001 0.0004 0.0004 0.0003 0.0075 0.0002 0.0001 0.0004 0 0.0007
Bud Periphery 0.0078 0.0005 0.0075 0.0154 0.001 0.0033 0.0101 0 0.0123 0.0004 0.0097 0.0113 0.0003 0.0006 0.0015 0.0017 0 0.0001
Bud Site 0.004 0.011 0.0083 0.038 0.0034 0.0005 0.0054 0 0.0029 0.0005 0.002 0.0001 0.0017 0.0024 0.0001 0.0006 0 0.0009
Cell Periphery 0.0016 0.0002 0.0004 0.0008 0.0003 0.0001 0.0005 0.0001 0.0003 0 0.0002 0.0002 0.0001 0.0002 0.0001 0.0001 0.0001 0
Cytoplasm 0.0349 0.0146 0.0112 0.0189 0.0048 0.0253 0.038 0.0109 0.0137 0.0047 0.0299 0.0325 0.0184 0.0343 0.0242 0.0211 0.0494 0.0422
Cytoplasmic Foci 0.0262 0.003 0.0065 0.0199 0.0036 0.0051 0.049 0.0012 0.0044 0.0323 0.0053 0.0034 0.0117 0.0074 0.0026 0.0021 0.0037 0.0069
Eisosomes 0.0008 0.0001 0.0005 0.0003 0.0005 0.0001 0.0003 0.0001 0.0007 0.0001 0.0001 0.0001 0.0006 0.0004 0.0004 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0078 0.0002 0.0013 0.0037 0.0016 0.0008 0.002 0.0004 0.0005 0.0001 0.0026 0.0019 0.0004 0.0003 0.0005 0.0003 0.0005 0.0002
Endosome 0.018 0.0005 0.0031 0.0152 0.0055 0.0021 0.0208 0.0001 0.0123 0.0056 0.0287 0.0009 0.0035 0.001 0.0005 0.0007 0.0008 0.0003
Golgi 0.0022 0.0001 0.0027 0.003 0.0023 0.0012 0.0151 0 0.0055 0.0054 0.0022 0.0005 0.002 0.0007 0.0001 0.0001 0 0.0001
Lipid Particles 0.0057 0.0001 0.0037 0.019 0.0019 0.0011 0.0079 0.0001 0.0007 0.0033 0.0033 0.0009 0.0042 0.0019 0.0004 0.0002 0.0003 0.0003
Mitochondria 0.0023 0.0002 0.0043 0.003 0.0012 0.0009 0.0133 0.0001 0.0018 0.008 0.0438 0.0057 0.0015 0.0008 0.0003 0.0004 0.0001 0.0002
None 0.761 0.9582 0.8951 0.7568 0.9412 0.9346 0.7562 0.9864 0.9347 0.8863 0.8022 0.9236 0.9088 0.9306 0.9676 0.9646 0.9444 0.9465
Nuclear Periphery 0.0228 0.0002 0.0036 0.0078 0.0035 0.0022 0.003 0.0001 0.0005 0.0001 0.0114 0.0011 0.0002 0.0001 0.0001 0.0004 0.0001 0.0001
Nucleolus 0.0033 0.0006 0.0012 0.0038 0.0007 0.0004 0.0176 0 0.0003 0.0004 0.0005 0.0001 0.0002 0.0002 0.0001 0.0004 0 0.0001
Nucleus 0.0206 0.0031 0.0053 0.0168 0.0017 0.004 0.0074 0.0001 0.0025 0.0002 0.0135 0.0005 0.0002 0.0002 0.0002 0.0014 0.0001 0.0001
Peroxisomes 0.0055 0.0001 0.0036 0.0088 0.0009 0.0007 0.0042 0 0.0004 0.0471 0.0151 0.0107 0.0214 0.0174 0.0001 0.0001 0 0.0003
Punctate Nuclear 0.0256 0.0055 0.0072 0.0108 0.0027 0.0032 0.0228 0.0001 0.0006 0.0037 0.0016 0.0011 0.0009 0.0003 0.0002 0.0024 0.0002 0.0004
Vacuole 0.0093 0.0002 0.0008 0.0025 0.0007 0.0015 0.0022 0.0001 0.0004 0.0002 0.0131 0.0004 0.0003 0.0004 0.0002 0.0007 0.0003 0.0001
Vacuole Periphery 0.0016 0 0.0004 0.0008 0.0004 0.0006 0.0008 0 0.0001 0.0001 0.0034 0.0001 0.0001 0 0 0.0001 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.7339 11.379 7.9993 6.8314 12.5949 8.0349 13.9274 10.4218 9.2802 12.5018
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
21 1527 161 1597 116 901 2712 1493 137 2428 2873 3090

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 845.59 678.27 832.01 791.16 641.20 679.65 760.69 789.45 672.53 678.78 764.69 790.33
Standard Deviation 91.41 94.88 111.56 109.42 74.38 83.51 93.87 105.07 106.71 90.83 96.36 107.35
Intensity Change Log 2 — -0.318099 -0.023357 -0.095989 — 0.084018 0.246534 0.300073 — -0.130802 0.099274 0.088281

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001051 0.000243 0.000997 0.000617 0.000090 0.000180 0.000095 0.000450 0.000237 0.000220 0.000146 0.000536
Bud Neck 0.013281 0.028155 0.001394 0.008404 0.026390 0.042208 0.010790 0.013311 0.024381 0.033370 0.010263 0.010775
Bud Site 0.024827 0.011296 0.003083 0.034488 0.001579 0.016365 0.019789 0.030596 0.005143 0.013177 0.018853 0.032608
Cell Periphery 0.000444 0.000146 0.000261 0.000245 0.000211 0.000807 0.000132 0.000208 0.000247 0.000391 0.000139 0.000227
Cytoplasm 0.218678 0.453042 0.400472 0.440419 0.367968 0.345119 0.526099 0.461722 0.345084 0.412993 0.519059 0.450712
Cytoplasmic Foci 0.182118 0.242889 0.027862 0.021696 0.316426 0.265083 0.009794 0.030806 0.295839 0.251125 0.010807 0.026098
Eisosomes 0.000276 0.000157 0.000090 0.000051 0.000304 0.000284 0.000022 0.000060 0.000299 0.000204 0.000026 0.000055
Endoplasmic Reticulum 0.001073 0.000516 0.006748 0.002056 0.000367 0.001377 0.000595 0.001973 0.000475 0.000836 0.000939 0.002016
Endosome 0.051438 0.016853 0.004888 0.004242 0.013302 0.028639 0.002234 0.007045 0.019148 0.021226 0.002382 0.005596
Golgi 0.006640 0.002924 0.000205 0.001120 0.001316 0.005783 0.000300 0.004685 0.002132 0.003985 0.000295 0.002842
Lipid Particles 0.007759 0.007318 0.003593 0.001504 0.012764 0.022506 0.000476 0.002215 0.011997 0.012954 0.000651 0.001848
Mitochondria 0.000880 0.010210 0.000288 0.004186 0.005723 0.015383 0.001739 0.005690 0.004980 0.012130 0.001658 0.004913
Mitotic Spindle 0.000895 0.004142 0.001549 0.039794 0.000135 0.002927 0.011047 0.025526 0.000252 0.003691 0.010515 0.032900
None 0.000415 0.002775 0.003838 0.004378 0.001361 0.003178 0.003650 0.003974 0.001216 0.002924 0.003661 0.004183
Nuclear Periphery 0.000622 0.000399 0.001154 0.001881 0.000386 0.000858 0.001062 0.001584 0.000422 0.000569 0.001067 0.001738
Nuclear Periphery Foci 0.000491 0.000328 0.004644 0.000947 0.000282 0.001068 0.000207 0.000826 0.000314 0.000602 0.000456 0.000889
Nucleolus 0.000726 0.001452 0.000924 0.000607 0.000988 0.001919 0.000454 0.000654 0.000948 0.001625 0.000480 0.000630
Nucleus 0.149064 0.131481 0.460181 0.324243 0.202024 0.162604 0.376835 0.294516 0.193906 0.143030 0.381505 0.309880
Peroxisomes 0.013375 0.012016 0.001399 0.000598 0.018611 0.016378 0.000324 0.001524 0.017809 0.013634 0.000385 0.001046
Vacuole 0.322960 0.072319 0.076205 0.105941 0.029312 0.064288 0.033682 0.109572 0.074324 0.069339 0.036065 0.107695
Vacuole Periphery 0.002987 0.001340 0.000228 0.002582 0.000458 0.003046 0.000673 0.003062 0.000846 0.001973 0.000648 0.002814

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.11 -0.25 0.77 -2.99 1.64 -2.04 0.01 -4.33 -2.86 -4.77 0.05 0.70 -1.69 -3.94 -5.21
Bud Neck -3.67 2.06 0.75 10.53 -8.44 -1.64 1.73 1.74 9.32 0.11 -1.18 1.79 1.91 13.71 0.88
Bud Site 1.10 1.67 0.30 -4.03 -7.44 -5.48 -8.76 -8.20 -0.89 -1.02 -3.23 -4.09 -5.81 -3.70 -2.02
Cell Periphery 2.25 0.74 1.95 -0.88 3.32 -1.59 4.04 2.72 1.78 -1.79 -1.06 4.23 2.82 1.67 -1.67
Cytoplasm -4.33 -2.26 -2.55 9.15 -0.26 0.81 -5.23 -0.87 -3.67 11.24 -3.13 -6.23 -1.31 5.33 14.66
Cytoplasmic Foci -2.25 3.87 4.16 39.77 2.23 2.52 15.76 14.95 32.17 -9.94 2.34 15.74 15.14 50.84 -9.97
Eisosomes 1.68 2.46 3.60 14.80 4.63 0.58 7.11 6.08 9.88 -17.30 2.67 7.74 6.81 15.28 -17.68
Endoplasmic Reticulum 2.07 -6.66 -6.52 -18.02 5.10 -1.80 -4.93 -9.44 -1.77 -7.81 -1.57 -6.78 -15.70 -8.03 -10.33
Endosome 1.10 1.59 1.72 13.23 3.11 -3.89 3.39 2.65 11.57 -4.05 -0.78 3.46 3.10 16.96 -4.09
Golgi 0.54 1.15 1.08 6.59 -1.53 -4.58 3.12 -0.94 3.07 -2.47 -2.43 2.34 0.78 4.87 -2.71
Lipid Particles -0.30 0.81 1.91 9.61 3.41 -2.97 5.21 4.61 9.88 -7.10 -0.39 5.44 4.93 12.81 -8.86
Mitochondria -6.17 0.88 -2.35 4.93 -3.92 -2.34 1.10 0.70 6.75 -2.08 -2.08 1.08 0.68 7.90 -2.36
Mitotic Spindle -2.32 -0.25 -8.55 -7.36 -8.22 -2.49 -7.82 -7.41 -5.58 -2.45 -4.21 -7.73 -11.62 -9.15 -5.36
None -4.69 -6.76 -5.85 -1.45 -0.73 -2.39 -4.83 -4.87 -0.76 -0.97 -3.35 -5.97 -5.50 -1.71 -1.05
Nuclear Periphery 0.76 -3.82 -10.63 -18.76 -10.05 -2.92 -16.10 -17.55 -8.76 -9.69 -1.99 -15.33 -23.36 -20.71 -15.03
Nuclear Periphery Foci 0.82 -5.58 -2.93 -6.02 4.89 -1.38 0.43 -4.11 0.31 -7.44 -1.17 -1.82 -5.38 -2.17 -4.53
Nucleolus -3.27 -1.18 -0.02 5.27 1.74 -2.32 2.47 2.00 5.09 -1.67 -2.55 2.42 1.88 7.40 -2.02
Nucleus 0.90 -4.94 -3.27 -26.82 4.70 2.36 -12.20 -7.47 -18.42 8.74 3.48 -12.84 -8.76 -33.00 9.49
Peroxisomes -0.08 1.70 1.88 12.44 1.27 0.51 3.42 3.31 10.21 -3.77 0.93 3.70 3.64 15.93 -2.72
Vacuole 3.99 3.26 2.09 -17.40 -5.49 -6.36 -4.01 -21.27 -17.22 -21.72 0.18 1.67 -8.27 -24.27 -29.42
Vacuole Periphery 1.10 2.24 1.07 0.15 -2.15 -6.21 -0.56 -2.14 2.55 -1.92 -4.90 1.08 -1.62 1.63 -2.36
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin; relocalizes from nucleus to plasma membrane upon DNA replication stress
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Flr1

Flr1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Flr1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available