Standard name
Human Ortholog
Description Alpha-1,2-mannosyltransferase; responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.09 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0.05 0.05 0.06 0.08 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.17 0.37 0.12 0.12 0.14 0.16 0.19 0.14 0.15 0.23 0.21 0.19 0.16 0.45 0.54 0.37 0.19 0.19 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.1 0 0 0 0 0 0 0 0 0 0 0.14 0.14 0 0.05 0 0 0 0 0 0 0 0
Endosome 0.22 0 0.38 0.43 0.45 0.32 0.27 0.35 0.2 0.23 0.12 0.27 0.3 0.17 0.22 0.11 0.16 0.11 0.29 0.3 0.38 0.36 0.25 0.18
Golgi 0.06 0.12 0.09 0.16 0.09 0 0 0 0 0 0 0 0.06 0 0 0 0 0.09 0.32 0.31 0.43 0.3 0.23 0.16
Mitochondria 0.29 0.33 0.28 0.32 0.23 0.4 0.39 0.37 0.5 0.41 0.5 0.4 0 0 0 0.07 0 0.05 0.06 0.07 0 0.11 0.13 0.1
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0.05 0 0 0 0.05 0.05 0.06 0.09 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.45 0.26 0.33 0.15 0.24 0.19 0.2 0.18 0.18 0.21 0.19 0.19 0.33 0.17 0.14 0.71 0.68 0.72 0.29 0.27 0.1 0.17 0.34 0.52
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 4 5 2 2 4 3 0 9 5 3 2 0 58 55 25 1 2 0 2 1 3 0 8 3
Bud 1 1 2 5 7 9 10 27 15 20 26 20 11 14 13 1 0 1 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 4 5 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 0 2 1 0 4 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 0 1 1 1 0 2 0 2 1 2 1 2 4 3 0 0 0 0 0 0 0 0 0
Cytoplasm 24 53 29 27 35 44 60 68 43 80 63 66 91 270 378 93 15 18 0 1 0 2 2 5
Endoplasmic Reticulum 5 15 0 5 5 4 8 6 5 4 3 2 80 85 30 12 1 4 0 0 2 2 7 3
Endosome 31 6 89 93 110 87 86 174 59 79 36 95 172 103 153 28 12 10 46 60 104 86 135 86
Golgi 8 18 21 35 21 12 14 22 10 3 4 3 33 2 2 5 2 8 51 61 119 70 126 75
Mitochondria 40 48 65 70 58 110 121 183 144 141 154 142 23 2 4 17 2 5 8 14 8 26 71 48
Nucleus 0 0 1 0 0 2 0 6 1 3 0 5 0 1 2 12 4 2 0 0 0 0 0 0
Nuclear Periphery 1 0 0 1 3 2 2 1 0 1 1 0 1 0 0 1 1 0 0 1 0 0 0 1
Nucleolus 1 0 1 6 7 7 12 18 5 12 11 7 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 1 3 8 6 10 4 15 3 10 10 12 0 1 3 1 0 0 0 1 6 7 3 1
SpindlePole 2 1 5 9 11 12 6 27 12 9 8 17 30 38 61 2 2 1 1 0 1 0 0 0
Vac/Vac Membrane 62 37 77 33 59 52 62 88 52 71 59 68 191 99 100 181 52 68 45 53 29 41 184 248
Unique Cell Count 139 144 235 217 247 272 313 501 289 345 307 353 580 596 697 254 77 94 159 199 278 239 547 479
Labelled Cell Count 182 185 296 295 327 355 387 646 357 437 383 440 692 678 779 354 93 117 159 199 278 239 547 479


Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 6.7 6.8 7.5 7.5 7.0 6.8 6.8 6.7 6.3 6.5 6.4 7.0 6.2 6.0 6.4 6.8 9.0 7.6 7.5 7.5
Std Deviation (1e-4) 0.9 1.1 1.4 1.5 2.0 1.5 1.4 1.4 1.3 1.2 1.2 1.0 0.7 0.6 0.7 1.4 1.5 2.3 1.3 1.5 1.3
Intensity Change (Log2) – – – 0.14 0.14 0.03 0.0 -0.01 -0.03 -0.12 -0.07 -0.1 0.03 -0.14 -0.18 -0.09 0.0 0.4 0.16 0.14 0.14


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 4.5 4.3 2.2 0 0 0
Bud 0 0 1.9 1.9 3.0 2.8 3.1 4.0 3.0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.6 1.2 2.1 0.5 0.8 3.3 2.5 2.1 1.2 8.9 11.2 6.2 1.6 1.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 6.0 6.1 3.2 3.4 0 0
Endosome 1.1 1.5 -1.4 -2.6 -0.8 -4.4 -3.9 -7.2 -2.8 -2.3 -6.3 -4.8 -7.0 -3.6 -4.9
Golgi 2.3 -0.2 -2.1 -2.1 -2.5 -2.6 -4.8 -4.2 -4.9 -1.7 -6.8 -7.4 -3.4 -1.8 -0.1
Mitochondria 1.1 -1.1 3.0 2.7 2.4 5.2 3.3 5.3 3.1 -9.9 -13.0 -13.7 -6.2 -4.6 -4.5
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 3.0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 2.6 2.5 0 2.4 2.5 0 0 0 0 0 0 0
Peroxisomes 1.7 0 1.7 0 1.4 0 1.3 1.5 1.6 0 0 0 0 0 0
SpindlePole 1.2 1.4 1.4 0 2.0 1.3 0.4 0.4 1.7 1.9 2.5 3.4 0 0 0
Vacuole -4.3 -2.2 -3.5 -3.5 -4.6 -3.9 -3.3 -3.6 -3.7 0 -5.1 -6.2 8.5 5.4 6.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.754 4.4869 3.7545 3.3893 3.5147 4.2534 4.925 7.2072 7.1294 5.5307 6.8158 7.2505 5.4644 7.3352 6.3459 6.4333 7.0561 6.6537
Actin 0.0187 0.0001 0.0003 0 0 0.0002 0.0086 0.0014 0.0006 0.0001 0 0.0005 0.0006 0.0003 0.0023 0.0001 0 0.0004
Bud 0.0006 0.0002 0.0002 0.0017 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0001
Bud Neck 0.002 0.0007 0.0002 0.0007 0.0002 0.0005 0.0002 0.0005 0.0002 0.0004 0.0001 0.0002 0.0001 0.0004 0.0002 0.0001 0.0001 0.0003
Bud Periphery 0.0009 0.0003 0.0002 0.0013 0.0001 0.0003 0.0006 0.0004 0.0001 0.0001 0 0.0002 0.0001 0.0002 0.0002 0.0001 0.0001 0.0002
Bud Site 0.0042 0.0005 0.0003 0.0113 0.0003 0.0003 0.0002 0.0005 0.0001 0.0007 0.0001 0.0001 0.0002 0.0003 0.0001 0.0001 0.0002 0.0002
Cell Periphery 0.0004 0.0004 0.0001 0.0022 0.0001 0.0007 0.0003 0.0009 0.0001 0.0001 0.0001 0.0001 0.0002 0.0002 0.0002 0.0002 0.0002 0.0002
Cytoplasm 0.0102 0.0168 0.0042 0.0043 0.0024 0.0093 0.0075 0.0045 0.0019 0.0031 0.0013 0.0046 0.0049 0.003 0.003 0.0024 0.0027 0.0025
Cytoplasmic Foci 0.0273 0.0316 0.0332 0.019 0.0209 0.0298 0.0429 0.0467 0.0367 0.0514 0.0321 0.0218 0.0405 0.0501 0.0343 0.01 0.0246 0.0251
Eisosomes 0.0004 0 0 0 0 0 0.0016 0.0004 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0115 0.0051 0.002 0.0017 0.0012 0.0023 0.0055 0.0019 0.0035 0.0008 0.0007 0.0017 0.008 0.0019 0.0033 0.0023 0.0015 0.0038
Endosome 0.5134 0.5547 0.6251 0.6308 0.5778 0.5412 0.5124 0.5353 0.4711 0.582 0.593 0.3957 0.5474 0.5069 0.5705 0.4584 0.574 0.5073
Golgi 0.0919 0.0801 0.1504 0.0687 0.0746 0.147 0.333 0.2672 0.3871 0.2384 0.1787 0.3609 0.2263 0.2802 0.1954 0.1017 0.2198 0.2349
Lipid Particles 0.0198 0.0065 0.0057 0.0027 0.0032 0.0098 0.0101 0.0103 0.0075 0.0116 0.0053 0.0241 0.0087 0.0141 0.0053 0.0037 0.0312 0.0089
Mitochondria 0.0296 0.0088 0.0313 0.0031 0.0032 0.0165 0.0227 0.0441 0.0572 0.0157 0.0031 0.0207 0.0169 0.0084 0.0453 0.0127 0.0032 0.0346
None 0.0092 0.0002 0.0003 0.0001 0.0001 0.0004 0.0155 0.0086 0.0001 0.0002 0 0.0033 0.012 0.0001 0.0001 0.0001 0.0006 0.0001
Nuclear Periphery 0.0309 0.0076 0.0029 0.0026 0.0016 0.0029 0.0045 0.0007 0.0024 0.001 0.0006 0.0031 0.0035 0.0015 0.0016 0.0024 0.0014 0.0045
Nucleolus 0.0023 0.0003 0.0001 0.0027 0.0002 0.0008 0.0001 0.0002 0 0.0003 0.0001 0.0002 0.0002 0.0001 0.0001 0.0001 0.0003 0.0002
Nucleus 0.0131 0.0014 0.0005 0.0016 0.0005 0.0015 0.0006 0.0003 0.0001 0.0002 0.0002 0.0003 0.0005 0.0005 0.0002 0.0004 0.0003 0.0004
Peroxisomes 0.0042 0.0008 0.001 0.0003 0.0004 0.0009 0.004 0.0035 0.0011 0.0015 0.0006 0.002 0.0016 0.0026 0.0121 0.0003 0.0004 0.0013
Punctate Nuclear 0.0067 0.0001 0.0001 0.0001 0 0.0005 0.0011 0.0001 0 0.0002 0 0.0001 0.0002 0.0001 0.0001 0 0.0002 0.0001
Vacuole 0.1263 0.2091 0.093 0.169 0.2305 0.1618 0.0151 0.0457 0.0145 0.046 0.1179 0.0883 0.0808 0.0755 0.0814 0.1891 0.0948 0.0944
Vacuole Periphery 0.0764 0.0746 0.0487 0.076 0.0824 0.0731 0.0133 0.0267 0.0156 0.0462 0.0658 0.0718 0.047 0.0536 0.0444 0.2158 0.0446 0.0806

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 127.931 88.5209 44.8789 60.9485 84.5289 65.1595 81.7205 61.9096 60.7155 95.58
Translational Efficiency 0.909 0.9289 1.1287 0.8656 0.9716 1.4623 0.8163 0.7935 0.8 0.7752

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
180 1094 84 79 1368 1841 256 1698 1548 2935 340 1777

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 955.70 887.09 1052.93 940.24 814.99 895.51 1073.88 925.69 831.35 892.37 1068.70 926.34
Standard Deviation 118.74 127.51 102.39 111.18 525.97 120.12 117.66 120.92 498.15 122.99 114.43 120.54
Intensity Change Log 2 — -0.107477 0.139780 -0.023529 — 0.135927 0.397979 0.183747 — 0.009671 0.264379 0.075583

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.012908 0.001199 0.002439 0.016783 0.002129 0.001271 0.003219 0.010811 0.003382 0.001244 0.003026 0.011077
Bud Neck 0.005878 0.000278 0.001470 0.003518 0.000525 0.000688 0.000738 0.003842 0.001147 0.000535 0.000919 0.003828
Bud Site 0.031246 0.003383 0.012669 0.047745 0.005250 0.001245 0.008674 0.021120 0.008273 0.002042 0.009661 0.022303
Cell Periphery 0.000196 0.000038 0.000072 0.000146 0.000103 0.000057 0.000042 0.000059 0.000114 0.000050 0.000049 0.000062
Cytoplasm 0.098030 0.002770 0.006896 0.030043 0.005189 0.001644 0.002628 0.031262 0.015984 0.002064 0.003683 0.031208
Cytoplasmic Foci 0.207290* 0.241719* 0.430510* 0.280759* 0.182458* 0.159188 0.387630* 0.277879* 0.185345* 0.189950* 0.398224* 0.278007*
Eisosomes 0.000062 0.000032 0.000038 0.000094 0.000044 0.000053 0.000035 0.000064 0.000046 0.000045 0.000036 0.000065
Endoplasmic Reticulum 0.000893 0.000175 0.005348 0.004699 0.000321 0.000231 0.000554 0.001271 0.000388 0.000210 0.001738 0.001423
Endosome 0.164599 0.250374* 0.288782* 0.265107* 0.301267* 0.320165* 0.265806* 0.303465* 0.285376* 0.294151* 0.271482* 0.301760*
Golgi 0.038599 0.442394* 0.096399 0.087069 0.440653* 0.457850* 0.232034* 0.189888* 0.393902* 0.452089* 0.198524* 0.185317*
Lipid Particles 0.002477 0.003812 0.010899 0.015424 0.006939 0.007327 0.010713 0.009106 0.006420 0.006017 0.010759 0.009387
Mitochondria 0.008449 0.013226 0.000282 0.006909 0.016658 0.017288 0.001090 0.005871 0.015703 0.015774 0.000890 0.005917
Mitotic Spindle 0.010309 0.005636 0.064754 0.022933 0.000674 0.000700 0.032768 0.016650 0.001794 0.002540 0.040670 0.016929
None 0.000060 0.000056 0.000009 0.000085 0.000526 0.000167 0.000005 0.000031 0.000472 0.000125 0.000006 0.000033
Nuclear Periphery 0.000262 0.000026 0.000136 0.000261 0.000053 0.000097 0.000236 0.000150 0.000077 0.000071 0.000211 0.000155
Nuclear Periphery Foci 0.000960 0.000187 0.002398 0.004759 0.000255 0.000425 0.002585 0.000918 0.000337 0.000336 0.002539 0.001088
Nucleolus 0.000182 0.000072 0.000061 0.000183 0.000250 0.000264 0.000059 0.000223 0.000242 0.000193 0.000060 0.000222
Nucleus 0.007682 0.000079 0.000456 0.006622 0.003816 0.000106 0.000262 0.000879 0.004265 0.000096 0.000310 0.001134
Peroxisomes 0.062684 0.007981 0.019140 0.065799 0.012051 0.006815 0.022457 0.039781 0.017939 0.007250 0.021637 0.040937
Vacuole 0.341278* 0.016177 0.049735 0.136024 0.011726 0.015358 0.025695 0.079591 0.050046 0.015663 0.031634 0.082100
Vacuole Periphery 0.005955 0.010387 0.007507 0.005038 0.009115 0.009062 0.002771 0.007141 0.008747 0.009556 0.003941 0.007047

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.58 1.33 -0.61 -2.08 -1.87 1.57 -1.63 -5.71 -6.41 -4.75 2.29 -0.13 -4.98 -6.79 -5.25
Bud Neck 5.19 3.88 1.81 -6.00 -3.37 -0.65 -1.93 -6.52 -5.93 -5.85 2.90 0.53 -5.56 -6.64 -5.80
Bud Site 4.08 2.19 -0.86 -2.49 -1.83 3.07 -1.19 -7.55 -11.68 -2.96 4.18 -0.90 -6.57 -11.23 -3.58
Cell Periphery 1.33 0.92 0.12 -3.11 -1.86 2.53 3.48 2.73 -0.14 -1.73 3.24 3.18 2.65 -1.46 -1.33
Cytoplasm 8.15 7.64 3.80 -3.83 -3.32 3.32 1.20 -11.87 -14.17 -12.70 7.73 5.91 -6.23 -14.54 -12.61
Cytoplasmic Foci -4.71 -9.50 -3.01 -0.33 5.74 4.93 -14.83 -14.98 -20.56 8.14 -1.82 -17.83 -15.32 -15.45 10.20
Eisosomes 4.02 2.24 -2.36 -4.24 -3.54 -1.15 1.49 -4.07 -1.36 -5.19 0.09 1.93 -4.28 -3.57 -5.94
Endoplasmic Reticulum 4.62 -1.49 -1.92 -2.33 0.15 0.95 -1.78 -3.14 -3.58 -1.28 2.21 -2.00 -3.43 -4.20 0.61
Endosome -7.96 -6.64 -3.38 1.00 1.96 -2.49 3.06 1.33 3.85 -2.26 -2.01 1.14 -0.91 0.98 -1.75
Golgi -42.48* -4.82 -2.51 21.30 1.20 -2.08 15.98 31.63 35.36* 3.71 -7.53 16.72 26.13 40.59 1.83
Lipid Particles -1.77 -5.03 -3.93 -3.47 -1.04 -0.23 -1.22 -1.55 -1.34 0.54 0.33 -1.76 -2.26 -3.14 0.60
Mitochondria -1.36 1.16 0.06 1.40 -1.05 -0.29 8.26 5.71 7.96 -5.34 -0.18 8.33 5.33 8.16 -6.11
Mitotic Spindle 1.31 -2.94 -1.45 -2.36 2.20 -0.12 -4.09 -9.32 -9.31 1.97 -0.88 -5.23 -8.82 -8.39 3.02
None 1.51 3.04 -0.77 -1.22 -1.59 1.57 2.75 2.59 0.91 -6.89 1.90 2.82 2.59 0.90 -5.27
Nuclear Periphery 3.24 2.41 0.54 -5.00 -3.29 -0.65 -2.25 -3.87 -1.47 1.00 0.70 -1.88 -2.70 -2.74 0.72
Nuclear Periphery Foci 5.67 -1.48 -2.22 -2.76 -1.72 -0.75 -2.26 -2.25 -1.57 1.66 0.50 -2.64 -2.59 -2.72 1.72
Nucleolus 2.78 3.71 -0.04 -2.35 -2.93 -0.02 1.37 0.04 0.04 -2.41 0.35 1.52 0.00 -0.42 -2.59
Nucleus 3.46 3.34 0.39 -3.14 -3.02 3.01 2.51 2.01 -5.15 -1.68 3.99 3.49 2.56 -6.05 -2.98
Peroxisomes 4.00 2.72 -0.43 -3.41 -2.53 3.50 -1.98 -9.52 -12.37 -2.99 5.09 -1.24 -7.88 -12.80 -3.97
Vacuole 15.12 12.95 4.71 -6.06 -4.82 -1.86 -3.19 -18.81 -17.92 -8.53 8.99 3.05 -6.99 -18.92 -9.50
Vacuole Periphery -1.83 -0.70 0.05 2.51 0.85 0.04 5.20 1.98 2.34 -4.08 -0.89 3.48 1.68 3.20 -2.41
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Alpha-1,2-mannosyltransferase; responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
Localization
Cell Percentages Golgi (51%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mnn2

Mnn2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mnn2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available