Standard name
Human Ortholog
Description Endoplasmic reticulum membrane protein; required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.4 0.44 0.23 0.59 0.44 0.38 0.48 0.47 0.58 0.62 0.7 0.69 0.31 0.33 0.48 0.16 0.15 0.16 0 0 0 0 0 0
Endoplasmic Reticulum 0.06 0.14 0 0 0 0 0 0 0 0 0 0 0.53 0.5 0.4 0 0 0 0.2 0.25 0.18 0.22 0.23 0.25
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0 0 0 0.22 0.17 0.15 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.51 0.53 0.73 0.57 0.66 0.69 0.6 0.63 0.52 0.48 0.46 0.42 0.24 0.19 0.14 0.71 0.71 0.72 0.67 0.66 0.68 0.68 0.64 0.63
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 3 1 1 1 0 1 2 1 1 0 2 8 12 20 4 0 3 4 0 1 1 1 1
Bud 0 0 1 0 0 1 2 5 4 7 1 7 1 4 4 0 0 0 4 9 2 4 5 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 0 1 0 0 1 0 0 0 1 1 3 5 1 7 3 0 0 0 0 0 0 0 0
Cytoplasm 155 447 78 143 178 247 321 452 346 429 377 430 155 205 280 82 52 51 10 28 7 8 7 5
Endoplasmic Reticulum 24 142 13 9 8 15 15 12 10 14 13 11 263 307 233 16 9 11 101 281 65 122 121 135
Endosome 2 5 10 1 5 7 5 5 9 1 1 7 13 33 39 6 6 9 12 27 15 11 19 20
Golgi 10 29 13 3 1 0 2 7 1 5 3 0 16 6 6 21 15 11 6 8 9 11 14 14
Mitochondria 3 0 3 0 4 7 13 13 7 8 9 17 0 0 0 6 3 3 5 2 2 2 1 2
Nucleus 8 3 14 4 8 32 42 35 21 20 10 9 1 3 0 117 56 50 3 1 2 4 1 1
Nuclear Periphery 1 0 1 0 0 1 0 0 0 1 0 1 1 0 0 0 0 0 15 10 5 7 7 5
Nucleolus 37 2 0 0 2 4 1 4 1 1 1 2 0 0 0 1 0 6 1 0 0 0 1 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 1 0 1 0 1 0 0
Vac/Vac Membrane 198 536 253 137 266 452 403 608 309 334 249 263 117 116 84 370 242 236 342 757 248 374 330 339
Unique Cell Count 388 1011 345 241 404 651 675 966 597 689 542 625 496 614 587 521 339 327 514 1139 367 554 518 540
Labelled Cell Count 442 1167 388 298 473 767 805 1144 709 822 665 752 580 687 673 626 384 381 514 1139 367 554 518 540


Endoplasmic Reticulum, Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 19.7 18.4 13.3 13.9 14.0 12.7 11.3 12.2 12.3 12.0 11.3 11.7 16.1 13.9 12.2 17.5 15.8 14.1 20.0 19.6 20.8
Std Deviation (1e-4) 6.4 3.7 4.0 3.3 3.8 3.9 4.2 3.9 4.2 3.8 3.7 4.1 3.2 2.7 2.4 5.8 5.6 5.4 4.7 5.0 4.7
Intensity Change (Log2) – – – 0.07 0.08 -0.06 -0.23 -0.12 -0.11 -0.15 -0.23 -0.18 0.28 0.07 -0.12 0.4 0.26 0.09 0.59 0.56 0.65


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 3.1 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 9.0 6.2 4.9 7.7 7.9 10.5 12.0 13.6 13.8 2.8 3.5 7.6 -2.6 -2.4 -2.3
Endoplasmic Reticulum 0 -1.5 -1.3 -1.4 -2.9 -2.0 -1.7 -1.2 -1.9 15.0 14.6 12.0 -0.6 -0.8 -0.3
Endosome 0 -1.6 -2.1 -2.7 0 -1.5 0 0 -2.0 -0.2 1.8 2.5 -1.9 -1.0 -0.1
Golgi -1.8 -3.5 0 -4.4 -4.0 -4.4 -3.5 -3.5 0 -0.4 -3.0 -2.9 0.2 0.4 -0.3
Mitochondria 0 0 0 1.3 0 0 0 0 1.9 0 0 0 0 0 0
Nucleus -1.7 -1.7 0.6 1.4 -0.4 -0.4 -1.0 -2.0 -2.6 -4.2 -4.0 -4.9 7.4 5.4 5.0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -4.2 -2.2 -1.3 -4.3 -3.5 -6.5 -7.6 -8.0 -9.3 -14.3 -16.6 -18.1 -0.7 -0.6 -0.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.2969 11.3953 9.7719 10.2031 8.454 10.3499 13.6974 17.7025 15.0178 13.9321 13.9888 15.3495 13.3784 16.2725 14.7703 14.2465 14.9613 15.5727
Actin 0.001 0.0001 0.0015 0.0001 0.0005 0.0006 0.0004 0 0.0003 0.0001 0.0001 0.0001 0.0092 0.0002 0.0002 0 0.0011 0.0001
Bud 0.0012 0.0027 0.0044 0.0004 0.0007 0.001 0.0001 0.0002 0.0005 0.0004 0.0004 0.0004 0.0004 0.0004 0.0004 0.0004 0.0003 0.0004
Bud Neck 0.0012 0.0015 0.0015 0.0014 0.0016 0.0021 0.0004 0.0016 0.0028 0.0012 0.0029 0.0013 0.0007 0.0027 0.001 0.0011 0.0025 0.0018
Bud Periphery 0.0013 0.0013 0.0023 0.0016 0.0015 0.0033 0.0009 0.0009 0.0023 0.0022 0.003 0.002 0.001 0.0011 0.001 0.0013 0.0014 0.0016
Bud Site 0.0045 0.0049 0.0059 0.0012 0.0032 0.0019 0.0004 0.0004 0.0018 0.0009 0.0005 0.001 0.0006 0.0013 0.0008 0.0013 0.0006 0.0004
Cell Periphery 0.009 0.0117 0.0099 0.0176 0.0045 0.008 0.0256 0.0314 0.0212 0.0267 0.0357 0.0158 0.0065 0.0222 0.0187 0.021 0.0251 0.0095
Cytoplasm 0.0413 0.07 0.0355 0.0374 0.03 0.0287 0.0188 0.0068 0.0219 0.0107 0.0084 0.0144 0.0316 0.0848 0.0436 0.0294 0.0626 0.0346
Cytoplasmic Foci 0.0234 0.0047 0.0183 0.0051 0.0243 0.0097 0.0021 0.0003 0.0024 0.0006 0.0005 0.0013 0.0081 0.0027 0.0032 0.0104 0.0023 0.0032
Eisosomes 0.0001 0 0 0 0 0 0 0 0 0 0 0 0.0002 0 0 0 0 0
Endoplasmic Reticulum 0.2702 0.2453 0.2367 0.1462 0.2275 0.2392 0.4411 0.4229 0.3762 0.3441 0.2885 0.3737 0.4544 0.3063 0.3367 0.1187 0.2494 0.3252
Endosome 0.1451 0.0584 0.1339 0.1164 0.1238 0.0781 0.0516 0.0155 0.0513 0.0213 0.0182 0.0335 0.061 0.0311 0.0596 0.0653 0.0246 0.0418
Golgi 0.0095 0.0014 0.0071 0.0028 0.0065 0.0063 0.0023 0.0007 0.0066 0.0006 0.0008 0.0009 0.004 0.001 0.0019 0.0013 0.0008 0.0013
Lipid Particles 0.0287 0.0115 0.0125 0.0061 0.0484 0.0071 0.0125 0.0043 0.0161 0.0078 0.0121 0.0087 0.0136 0.0104 0.0087 0.0051 0.0081 0.0059
Mitochondria 0.0154 0.0022 0.0053 0.0027 0.0109 0.0058 0.0022 0.0002 0.0023 0.0003 0.0017 0.0009 0.003 0.001 0.0016 0.0008 0.0007 0.0012
None 0.0036 0.0005 0.002 0.0002 0.0007 0.0015 0.0004 0 0.0002 0.0001 0.0001 0.0002 0.003 0.0007 0.0007 0.0002 0.0015 0.0003
Nuclear Periphery 0.064 0.0332 0.0383 0.0209 0.0338 0.0514 0.044 0.0229 0.0319 0.0339 0.0379 0.0379 0.0764 0.0475 0.053 0.02 0.0351 0.0749
Nucleolus 0.0068 0.0044 0.0052 0.0015 0.0123 0.002 0.0005 0.0017 0.0006 0.0003 0.0006 0.0005 0.0032 0.0031 0.0013 0.001 0.0009 0.0008
Nucleus 0.0129 0.0119 0.0099 0.0045 0.007 0.0113 0.005 0.0025 0.0026 0.0029 0.0054 0.0039 0.0209 0.0176 0.0085 0.0054 0.008 0.0255
Peroxisomes 0.0036 0.0002 0.0025 0.0001 0.0105 0.0013 0.0001 0 0.0001 0 0 0 0.0031 0 0.0001 0.0001 0.0002 0
Punctate Nuclear 0.0086 0.0026 0.0039 0.0002 0.001 0.0015 0.0007 0 0.0001 0.0001 0.0001 0.0001 0.0061 0.0017 0.0006 0.0003 0.0054 0.0008
Vacuole 0.3186 0.5111 0.433 0.6015 0.4215 0.5087 0.3673 0.4699 0.4321 0.5304 0.5532 0.4738 0.271 0.4425 0.4241 0.6651 0.5538 0.4297
Vacuole Periphery 0.0301 0.0205 0.0303 0.032 0.0299 0.0304 0.0235 0.0176 0.0269 0.0154 0.03 0.0297 0.0219 0.0218 0.0344 0.0516 0.0158 0.0408

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 84.5675 73.5982 83.7004 80.5189 75.4175 81.3903 91.4011 88.44 105.7234 81.8325
Translational Efficiency 0.9994 1.0575 0.9147 1.0595 0.8565 1.1239 0.9512 0.9807 0.8614 0.8473

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2191 1419 271 978 1635 1730 1947 1387 3826 3149 2218 2365

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1160.63 1379.14 1525.50 1303.44 1210.69 1353.42 1586.26 1636.22 1182.02 1365.01 1578.84 1498.61
Standard Deviation 182.20 261.67 209.78 316.47 259.47 412.95 243.64 318.94 219.98 353.13 240.58 357.68
Intensity Change Log 2 — 0.248861 0.394374 0.167416 — 0.160780 0.389800 0.434537 — 0.204563 0.392040 0.309959

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000013 0.000079 0.000145 0.000845 0.000043 0.000058 0.000406 0.000601 0.000026 0.000067 0.000374 0.000702
Bud Neck 0.000463 0.000798 0.003602 0.005819 0.000845 0.000696 0.000841 0.002686 0.000626 0.000742 0.001179 0.003982
Bud Site 0.000526 0.002440 0.002266 0.021120 0.002662 0.001478 0.002880 0.011661 0.001438 0.001912 0.002805 0.015573
Cell Periphery 0.005571 0.008454 0.001217 0.001017 0.004219 0.003838 0.003389 0.007725 0.004993 0.005918 0.003124 0.004951
Cytoplasm 0.001046 0.007210 0.008172 0.048776 0.005703 0.002123 0.017997 0.021860 0.003036 0.004415 0.016797 0.032991
Cytoplasmic Foci 0.000635 0.001759 0.006240 0.024188 0.003832 0.001779 0.003807 0.011364 0.002002 0.001770 0.004105 0.016667
Eisosomes 0.000031 0.000010 0.000014 0.000020 0.000006 0.000007 0.000036 0.000036 0.000020 0.000008 0.000034 0.000029
Endoplasmic Reticulum 0.154519* 0.409383* 0.492773* 0.045309 0.142465* 0.258684* 0.806792* 0.348950* 0.149368* 0.326592* 0.768424* 0.223385*
Endosome 0.006668 0.014997 0.048961 0.079866 0.020485 0.011077 0.031123 0.061786 0.012573 0.012844 0.033302 0.069263
Golgi 0.000377 0.001480 0.003484 0.016252 0.002595 0.001879 0.005884 0.017837 0.001325 0.001699 0.005591 0.017181
Lipid Particles 0.000487 0.001035 0.016848 0.016039 0.000942 0.000727 0.021576 0.032744 0.000681 0.000866 0.020998 0.025836
Mitochondria 0.000219 0.000728 0.000078 0.004486 0.000216 0.000488 0.000550 0.002127 0.000218 0.000596 0.000492 0.003102
Mitotic Spindle 0.000011 0.000729 0.000949 0.014702 0.000027 0.000580 0.000654 0.002237 0.000018 0.000647 0.000690 0.007392
None 0.000013 0.000243 0.000007 0.002244 0.000717 0.001780 0.000946 0.000822 0.000314 0.001087 0.000831 0.001410
Nuclear Periphery 0.001836 0.001260 0.024778 0.004949 0.002819 0.003398 0.001535 0.000932 0.002256 0.002435 0.004375 0.002593
Nuclear Periphery Foci 0.000999 0.006542 0.087080 0.033082 0.007730 0.002419 0.014816 0.019959 0.003876 0.004277 0.023645 0.025386
Nucleolus 0.000244 0.000164 0.000049 0.002117 0.000624 0.000442 0.000049 0.000153 0.000406 0.000317 0.000049 0.000965
Nucleus 0.000241 0.000542 0.000731 0.005138 0.000737 0.001989 0.000690 0.000893 0.000453 0.001337 0.000695 0.002648
Peroxisomes 0.000039 0.000047 0.000067 0.001103 0.000060 0.000104 0.000220 0.000254 0.000048 0.000079 0.000201 0.000605
Vacuole 0.782889* 0.518956* 0.294360* 0.625809* 0.691264* 0.679175* 0.082008 0.425965* 0.743734* 0.606977* 0.107953 0.508607*
Vacuole Periphery 0.043174 0.023144 0.008181 0.047121 0.112007* 0.027278 0.003801 0.029407 0.072589 0.025415 0.004336 0.036732

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.94 -4.37 -2.94 -2.71 -2.46 -1.29 -1.99 -2.85 -2.77 -0.71 -5.13 -2.17 -4.13 -3.87 -1.40
Bud Neck -3.14 -6.32 -12.34 -11.41 -3.65 0.79 -0.38 -5.40 -5.61 -5.28 -1.21 -5.10 -12.43 -11.66 -9.80
Bud Site -4.98 -3.64 -9.90 -8.88 -8.87 1.76 -0.75 -7.24 -7.94 -6.86 -1.34 -3.60 -12.57 -11.87 -10.79
Cell Periphery -3.25 7.37 8.07 10.76 0.93 0.76 1.61 -4.79 -5.81 -6.38 -1.82 4.10 0.25 2.11 -3.90
Cytoplasm -5.59 -4.45 -12.48 -10.80 -10.22 3.79 -8.76 -8.09 -10.11 -1.79 -2.22 -12.00 -15.15 -14.27 -7.79
Cytoplasmic Foci -3.38 -3.40 -13.63 -12.92 -7.48 2.92 -0.13 -6.99 -8.87 -7.19 0.53 -4.74 -15.49 -15.48 -12.47
Eisosomes 0.93 0.76 0.51 -4.31 -2.27 -1.59 -8.99 -11.39 -10.38 0.29 0.91 -1.05 -0.67 -11.01 1.48
Endoplasmic Reticulum -25.05* -15.57 18.17 35.97* 20.75 -13.65 -75.77* -18.10 -7.12 38.50* -26.82 -79.70 -9.25 12.28 56.49*
Endosome -8.98 -9.25 -19.38 -16.74 -4.63 6.87 -5.80 -16.15 -20.36 -10.54 -0.41 -13.09 -26.50 -26.07 -13.36
Golgi -2.29 -2.17 -8.40 -7.51 -5.17 0.96 -3.97 -10.36 -10.22 -7.31 -0.86 -6.09 -13.76 -12.72 -8.44
Lipid Particles -3.15 -3.81 -7.91 -7.63 0.12 1.14 -11.56 -12.56 -12.62 -3.43 -1.49 -12.29 -14.81 -14.68 -1.93
Mitochondria -1.21 1.03 -4.27 -3.45 -4.48 -1.68 -5.39 -2.90 -2.40 -2.36 -1.77 -2.96 -5.05 -4.11 -4.56
Mitotic Spindle -1.18 -2.51 -7.01 -6.49 -6.47 -1.20 -2.80 -4.24 -2.38 -2.69 -1.68 -3.33 -7.91 -6.84 -7.02
None -2.05 1.41 -3.14 -2.74 -3.15 -1.25 -0.37 -0.20 1.13 0.21 -1.70 -1.11 -2.79 -0.44 -0.92
Nuclear Periphery 1.80 -6.39 -4.10 -4.97 5.36 -0.77 1.95 3.22 4.98 2.10 -0.45 -3.57 -1.00 -0.60 2.77
Nuclear Periphery Foci -5.62 -9.82 -10.03 -8.05 5.57 4.42 -4.37 -6.21 -9.82 -2.41 -0.64 -11.50 -12.47 -12.21 -1.02
Nucleolus 3.03 8.29 -2.46 -2.57 -2.72 1.18 6.11 4.90 2.49 -4.84 1.13 8.49 -1.76 -2.01 -2.90
Nucleus -2.23 -2.64 -7.64 -7.11 -6.73 -1.87 -0.02 -1.09 1.50 -0.73 -2.37 -1.25 -7.69 -3.25 -5.67
Peroxisomes -0.45 -1.19 -4.61 -4.58 -4.48 -0.93 -4.47 -5.91 -2.35 -0.66 -1.09 -4.72 -5.73 -5.16 -3.89
Vacuole 26.64* 26.58 15.14 -7.79 -16.09 1.36 83.91* 24.48 22.31 -34.81 20.40 108.33* 30.14 11.08 -48.29
Vacuole Periphery 8.83 16.95 -0.20 -6.95 -12.65 22.03* 29.81* 21.08 -0.86 -15.52* 21.83 34.61 15.54 -5.64 -20.75
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Endoplasmic reticulum membrane protein; required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages vacuole (31%), ER (12%), mixed (56%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Csg2

Csg2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Csg2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available