Standard name
Human Ortholog
Description Putative protein of unknown function; proposed to be involved in iron or copper homeostasis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0.05 0 – 0.07 0 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.05 0 0 0 – 0 0 0 0 0 0 0 0.12 0.1 0 0 0 0 0 0 0
Cytoplasm 0 0.18 0.21 0.22 0.21 0.15 0.16 – 0.14 0.19 0.2 0.19 0 0 0.05 0.08 0.06 0.1 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0.05 0 0 0.05 0 0 0 0 0 0 0 0
Endosome 0.26 0 0.16 0.15 0.24 0 0.19 – 0 0.06 0.05 0 0.06 0.07 0.12 0.19 0.33 0.1 0.15 0.12 0.07 0.1 0.09 0.06
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0.14 0.17 0.17 0.3 0.15 0.43 0 0 0 0 0 0
Mitochondria 0.63 0.83 0.41 0.59 0.42 0.79 0.57 – 0.78 0.76 0.8 0.74 0.8 0.79 0.67 0.12 0.16 0.14 0.59 0.63 0.75 0.71 0.69 0.69
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.09 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Peroxisomes 0.12 0 0.09 0.19 0.13 0 0.06 – 0 0 0 0 0 0 0.12 0.1 0.15 0.14 0 0 0.05 0 0 0
SpindlePole 0.08 0 0.21 0.09 0.11 0.06 0.14 – 0.12 0.09 0.07 0.1 0 0 0 0.06 0.12 0.12 0 0 0 0 0 0
Vac/Vac Membrane 0.06 0 0 0.06 0.19 0.06 0.1 – 0.05 0 0 0 0.11 0.09 0.08 0.16 0.24 0.12 0 0.08 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 3 0 1 2 0 – 0 0 0 0 2 3 2 3 0 1 1 0 2 4 5 9
Bud 0 3 1 1 4 10 9 – 14 2 11 20 1 4 5 1 1 1 0 0 0 0 5 1
Bud Neck 0 0 2 1 1 4 0 – 7 2 2 5 0 0 0 0 0 0 0 0 1 1 3 6
Bud Site 2 0 0 0 0 1 0 – 1 2 3 5 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 2 7 2 0 1 – 0 1 2 6 2 10 6 10 7 1 0 0 0 0 0 0
Cytoplasm 2 16 20 31 52 31 55 – 30 48 48 64 4 12 11 7 4 4 1 4 1 1 3 4
Endoplasmic Reticulum 0 4 2 0 1 3 1 – 0 1 0 1 6 4 4 4 3 1 0 1 2 1 0 1
Endosome 28 0 15 21 59 3 66 – 3 16 11 9 7 20 28 16 22 4 22 12 12 17 23 15
Golgi 1 0 0 0 1 0 0 – 0 0 0 0 16 49 40 25 10 18 6 2 2 2 5 4
Mitochondria 67 75 39 84 102 162 199 – 163 194 191 249 93 228 161 10 11 6 86 64 130 117 175 167
Nucleus 3 2 1 1 3 8 14 – 3 4 6 8 0 1 0 3 1 0 0 1 0 0 0 1
Nuclear Periphery 3 0 0 0 0 0 0 – 0 0 1 2 0 1 1 3 0 1 4 0 1 2 0 1
Nucleolus 10 0 0 0 0 3 3 – 0 0 0 1 0 1 0 1 2 2 1 0 1 0 1 1
Peroxisomes 13 0 9 27 32 1 21 – 2 8 4 8 2 10 29 8 10 6 5 1 9 5 11 6
SpindlePole 8 0 20 13 27 12 49 – 25 22 16 33 4 4 5 5 8 5 5 3 2 2 6 10
Vac/Vac Membrane 6 1 3 8 47 13 36 – 10 7 6 8 13 26 20 13 16 5 6 8 3 4 7 6
Unique Cell Count 106 90 95 142 244 205 347 208 256 240 335 116 287 241 83 67 42 147 102 173 165 253 242
Labelled Cell Count 143 104 117 194 332 253 454 258 307 301 419 150 373 312 109 95 55 147 102 173 165 253 242


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.4 3.9 5.1 5.3 5.8 3.9 4.6 – 3.9 4.4 4.0 4.0 6.2 6.1 6.5 7.6 8.2 8.2 4.6 4.8 4.7
Std Deviation (1e-4) 0.8 0.6 1.2 1.8 1.4 1.4 1.3 – 1.3 1.6 1.3 1.1 1.4 1.2 1.4 1.3 1.8 2.0 1.1 1.5 0.9
Intensity Change (Log2) – – – 0.07 0.17 -0.38 -0.15 – -0.38 -0.22 -0.34 -0.34 0.27 0.27 0.35 0.58 0.68 0.69 -0.13 -0.09 -0.12

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 –
Bud Neck – – – – – – – – – – – – 0 0 –
Bud Site – – – – – – – – – – – – 0 0 –
Cell Periphery – – – – – – – – – – – – 0 0 –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 –
Endosome – – – – – – – – – – – – 0 0 –
Golgi – – – – – – – – – – – – 0 0 –
Mitochondria – – – – – – – – – – – – 0 0 –
Nuclear Periphery – – – – – – – – – – – – 0 0 –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 –
Peroxisomes – – – – – – – – – – – – 0 0 –
SpindlePole – – – – – – – – – – – – 0 0 –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 –
Cytoplasm – – – – – – – – – – – – 0 0 –
Nucleus – – – – – – – – – – – – 0 0 –
Vacuole – – – – – – – – – – – – 2.9 4.0 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.1036 0.5231 0.259 0.0484 0.1301 0.2605 0.623 1.6938 1.3502 1.3008 0.8633 1.2987 2.583 3.4214 2.9679 3.071 2.4847 3.0662
Actin 0.0104 0.0081 0.0058 0.0014 0.0072 0.0027 0.0186 0.0031 0.008 0.0019 0.0022 0.0032 0.0141 0.0056 0.0212 0.0269 0.0475 0.0111
Bud 0.0008 0.0017 0.0018 0.0008 0.0005 0.0013 0.0012 0.0011 0.0022 0.001 0.0006 0.0004 0.0009 0.0057 0.002 0.0014 0.0014 0.0006
Bud Neck 0.0043 0.0012 0.0011 0.0011 0.0005 0.0021 0.0008 0.0034 0.0009 0.0004 0.0005 0.0014 0.005 0.0011 0.0012 0.0037 0.0005 0.0018
Bud Periphery 0.0022 0.0055 0.0054 0.0019 0.0008 0.0056 0.0014 0.0014 0.0065 0.0026 0.0017 0.0009 0.0018 0.0091 0.0064 0.0045 0.0037 0.0013
Bud Site 0.0059 0.0166 0.0107 0.0008 0.0009 0.0011 0.0033 0.0154 0.009 0.0007 0.0006 0.0007 0.0111 0.0307 0.0075 0.0044 0.0014 0.0012
Cell Periphery 0.0012 0.0006 0.0036 0.0003 0.0001 0.0015 0.0004 0.0004 0.0007 0.0003 0.0007 0.0003 0.0015 0.0008 0.0009 0.0005 0.0003 0.0003
Cytoplasm 0.0132 0.0097 0.0084 0.0073 0.0012 0.0166 0.0148 0.0139 0.0044 0.0031 0.0023 0.004 0.0207 0.0218 0.0233 0.0118 0.0036 0.0139
Cytoplasmic Foci 0.0612 0.0918 0.0741 0.058 0.0247 0.0812 0.0672 0.0581 0.0394 0.0435 0.0443 0.0324 0.0597 0.0698 0.0551 0.0568 0.054 0.0624
Eisosomes 0.0021 0.0003 0.001 0.0001 0.0001 0.0002 0.0004 0.0001 0.0002 0.0002 0.0003 0.0002 0.001 0.0004 0.0007 0.0008 0.0007 0.0003
Endoplasmic Reticulum 0.003 0.0014 0.0009 0.0004 0.0014 0.0011 0.0028 0.0003 0.0006 0.0005 0.0005 0.001 0.0077 0.0025 0.0038 0.0038 0.0026 0.0009
Endosome 0.1447 0.11 0.0965 0.1197 0.048 0.1172 0.1617 0.082 0.0739 0.1357 0.0827 0.074 0.1372 0.1149 0.0761 0.0848 0.0946 0.0874
Golgi 0.0599 0.098 0.0625 0.0694 0.0358 0.0676 0.0681 0.0752 0.0669 0.0665 0.1156 0.0625 0.0619 0.0954 0.0489 0.0836 0.1073 0.0731
Lipid Particles 0.058 0.0157 0.0377 0.0118 0.0087 0.0332 0.0458 0.0238 0.0151 0.0062 0.0087 0.0179 0.0705 0.0148 0.023 0.0271 0.0149 0.0303
Mitochondria 0.4751 0.5333 0.5439 0.6694 0.772 0.5331 0.5318 0.6477 0.7055 0.6506 0.6276 0.7282 0.4786 0.5179 0.6188 0.5311 0.5667 0.5635
None 0.052 0.0317 0.0438 0.0009 0.048 0.0315 0.0093 0.003 0.0025 0.0014 0.0003 0.0124 0.029 0.029 0.0258 0.0576 0.0054 0.0368
Nuclear Periphery 0.0033 0.0005 0.0004 0.0002 0.0049 0.0006 0.0016 0.0001 0.0004 0.0003 0.0006 0.0004 0.004 0.0004 0.0021 0.0005 0.0081 0.0011
Nucleolus 0.0079 0.0051 0.002 0.0002 0.0003 0.0005 0.0008 0.0005 0.0022 0.0002 0.0001 0.0004 0.0052 0.0007 0.0018 0.0004 0.0003 0.0006
Nucleus 0.0023 0.0014 0.0009 0.0003 0.0009 0.0006 0.0021 0.0004 0.001 0.0004 0.0001 0.0005 0.0032 0.0006 0.0013 0.0003 0.0007 0.0005
Peroxisomes 0.0636 0.0586 0.0848 0.0487 0.037 0.0902 0.0475 0.0628 0.0483 0.0735 0.0984 0.0497 0.0667 0.0708 0.0688 0.0904 0.0778 0.1041
Punctate Nuclear 0.0041 0.0013 0.0012 0.0002 0.0006 0.0011 0.0019 0.0009 0.0003 0.0003 0.0001 0.0004 0.0077 0.0004 0.0016 0.0009 0.002 0.0008
Vacuole 0.017 0.0051 0.0103 0.0041 0.0024 0.0071 0.0121 0.0039 0.0081 0.006 0.0041 0.0046 0.0083 0.0052 0.0063 0.0049 0.0029 0.0043
Vacuole Periphery 0.0078 0.0023 0.0033 0.0029 0.0039 0.0037 0.0062 0.0023 0.0038 0.0048 0.0079 0.0043 0.0043 0.0024 0.0033 0.0037 0.0037 0.0036

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 14.6285 9.3407 19.4073 13.2363 4.0642 25.0635 41.0829 37.6084 26.9514 27.6647
Translational Efficiency 2.6061 3.8702 1.1958 1.4377 3.0253 2.758 1.7776 1.6252 2.0794 1.8039

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1508 255 111 43 1525 2411 239 1418 3033 2666 350 1461

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 752.27 923.61 972.53 846.33 743.09 835.27 885.96 822.29 747.65 843.72 913.42 823.00
Standard Deviation 96.41 148.04 97.87 105.37 102.91 115.35 90.44 98.04 99.84 121.68 101.23 98.35
Intensity Change Log 2 — 0.296033 0.370492 0.169970 — 0.168706 0.253705 0.146110 — 0.234164 0.313638 0.158163

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000593 0.008056 0.007144 0.006398 0.000695 0.000887 0.000287 0.000442 0.000644 0.001573 0.002462 0.000618
Bud Neck 0.007079 0.006237 0.011754 0.007078 0.005845 0.006977 0.002655 0.007964 0.006458 0.006906 0.005541 0.007938
Bud Site 0.011114 0.025203 0.038224 0.029267 0.008717 0.012699 0.002894 0.024805 0.009908 0.013895 0.014099 0.024936
Cell Periphery 0.000535 0.000605 0.000477 0.000317 0.000449 0.000275 0.000190 0.000153 0.000492 0.000307 0.000281 0.000158
Cytoplasm 0.005718 0.011436 0.239272 0.301922 0.004569 0.005190 0.340903 0.544917 0.005140 0.005788 0.308672 0.537765
Cytoplasmic Foci 0.030561 0.049348 0.127068 0.135820 0.038119 0.047048 0.055753 0.058089 0.034361 0.047268 0.078370 0.060377
Eisosomes 0.000088 0.000114 0.000235 0.000155 0.000064 0.000078 0.000098 0.000063 0.000076 0.000081 0.000141 0.000065
Endoplasmic Reticulum 0.000377 0.000675 0.014673 0.003459 0.000524 0.000209 0.002689 0.001265 0.000451 0.000253 0.006490 0.001330
Endosome 0.070646 0.079597 0.061574 0.020058 0.080553 0.100296 0.007814 0.008623 0.075627 0.098316 0.024863 0.008960
Golgi 0.081571 0.093581 0.002835 0.002525 0.092333 0.133618 0.000124 0.001777 0.086983 0.129789 0.000984 0.001799
Lipid Particles 0.002550 0.002603 0.016163 0.011919 0.005313 0.002612 0.004066 0.001779 0.003939 0.002611 0.007902 0.002077
Mitochondria 0.728260 0.595926 0.001453 0.001567 0.692104 0.608854 0.000446 0.001508 0.710081 0.607617 0.000766 0.001509
Mitotic Spindle 0.006332 0.015790 0.022271 0.027193 0.009837 0.012557 0.001541 0.014266 0.008094 0.012866 0.008115 0.014646
None 0.000417 0.000241 0.001265 0.001658 0.000486 0.000362 0.005766 0.003676 0.000452 0.000350 0.004339 0.003617
Nuclear Periphery 0.000116 0.000118 0.002321 0.000813 0.000197 0.000124 0.001721 0.001040 0.000157 0.000124 0.001911 0.001033
Nuclear Periphery Foci 0.000141 0.000456 0.011556 0.002402 0.000288 0.000254 0.002129 0.000939 0.000215 0.000274 0.005119 0.000982
Nucleolus 0.000298 0.000163 0.004426 0.000899 0.000480 0.000725 0.001430 0.000770 0.000390 0.000672 0.002380 0.000774
Nucleus 0.000943 0.003390 0.200980 0.161075 0.001434 0.000803 0.475719 0.206282 0.001190 0.001051 0.388588 0.204951
Peroxisomes 0.021051 0.091643 0.033967 0.080267 0.028834 0.042258 0.001494 0.004584 0.024964 0.046982 0.011792 0.006811
Vacuole 0.013731 0.008215 0.199564 0.203762 0.011658 0.013768 0.092011 0.115139 0.012689 0.013237 0.126121 0.117747
Vacuole Periphery 0.017881 0.006603 0.002779 0.001445 0.017502 0.010405 0.000269 0.001920 0.017690 0.010041 0.001065 0.001906

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.14 -5.25 -1.84 0.95 0.94 -1.04 2.44 2.18 3.43 -0.50 -3.36 -4.19 0.99 3.83 4.48
Bud Neck 0.37 -1.85 0.48 0.13 1.85 -0.86 2.48 -1.47 -0.70 -5.26 -0.41 0.83 -1.14 -0.76 -2.04
Bud Site -2.40 -4.48 -1.49 -0.12 0.91 -2.76 4.39 -4.13 -2.46 -6.65 -3.00 -1.87 -3.95 -2.07 -1.58
Cell Periphery -0.41 0.30 2.08 2.34 2.89 2.06 3.08 3.85 7.21 2.84 2.54 2.78 5.07 7.69 5.96
Cytoplasm -1.59 -9.61 -6.12 -5.92 -0.84 -0.56 -19.36 -64.69 -64.79 -10.13 -0.81 -21.16 -64.34 -64.15 -13.19
Cytoplasmic Foci -3.51 -7.62 -3.55 -2.53 0.64 -3.73 -1.92 -4.28 -1.47 -0.45 -6.65 -6.64 -6.61 -1.91 3.06
Eisosomes -1.79 -5.79 -3.45 -2.27 2.58 -2.85 -4.77 -0.12 2.34 4.47 -0.84 -6.40 1.29 2.52 7.43
Endoplasmic Reticulum -1.67 -8.42 -4.79 -4.23 5.88 3.04 -8.90 -8.14 -16.86 6.10 3.20 -10.23 -12.19 -16.47 8.48
Endosome -1.08 1.46 9.99 7.50 4.06 -4.20 19.42 20.07 29.77 0.85 -6.01 12.86 26.43 30.99 4.88
Golgi -1.16 22.00 22.06 9.82 0.99 -7.68 23.79 23.45 35.45 -3.08 -9.78 32.64 32.37 36.70 -0.76
Lipid Particles -0.11 -6.06 -1.69 -1.63 1.78 2.75 1.16 3.98 1.91 5.49 2.07 -4.32 3.75 1.48 7.19
Mitochondria 5.26 92.14 91.96 24.20 0.31 7.51 80.97 80.87 86.09 -3.08 11.48 121.78 121.66 89.17 -1.92
Mitotic Spindle -2.44 -2.06 -0.69 -0.11 0.16 -1.80 5.07 -1.81 -0.60 -5.86 -4.23 0.15 -2.99 -0.50 -2.09
None 1.97 -3.90 -2.50 -2.85 -0.86 0.68 -5.48 -7.06 -7.66 2.00 0.77 -5.88 -7.64 -7.83 0.93
Nuclear Periphery -0.26 -6.80 -5.38 -5.25 3.54 0.84 -10.67 -11.67 -11.74 3.73 0.46 -12.78 -13.42 -12.22 4.46
Nuclear Periphery Foci -1.88 -5.02 -3.90 -3.24 3.89 0.27 -6.37 -3.31 -3.25 2.76 -0.64 -6.45 -3.78 -3.42 4.88
Nucleolus 1.07 -2.14 -2.11 -3.27 1.98 -0.84 -3.17 -1.76 -0.15 2.12 -1.11 -2.87 -2.89 -0.35 2.35
Nucleus -1.42 -8.23 -5.28 -5.18 0.36 0.98 -25.56 -38.22 -38.50 12.57 0.20 -23.81 -38.71 -38.74 9.28
Peroxisomes -5.79 -1.60 -1.14 1.39 -0.70 -4.00 11.76 10.70 15.32 -2.06 -7.53 5.16 11.00 15.56 2.54
Vacuole 2.60 -10.71 -6.03 -6.14 -1.46 -1.74 -10.42 -28.68 -28.26 -2.54 -0.60 -14.44 -29.07 -28.84 -0.70
Vacuole Periphery 6.65 12.20 13.22 4.31 2.27 5.57 15.40 13.82 12.90 -2.71 7.71 20.18 18.51 13.23 -0.77
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative protein of unknown function; proposed to be involved in iron or copper homeostasis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Localization
Cell Percentages mitochondrion (97%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Fmp23

Fmp23


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fmp23-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available