Standard name
Human Ortholog
Description Amino acid transporter for valine, leucine, isoleucine, and tyrosine; low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.14 0.2 0.16 0.11 0.09 0 0 0 0 0 0 0 0 0 0.06 0.27 0.3 0.21 0.1 0.1 0.13 0.08 0.07 0.07
Bud 0.07 0.08 0 0.06 0.06 0 0.05 0.05 0 0.05 0.06 0.05 0 0 0 0.09 0.12 0.08 0.06 0.06 0 0.06 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.08 0.07 0.06 0.05 0.06
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.33 0.34 0.26 0.31 0.17 0.11 0.07 0 0 0 0.05 0 0.26 0.26 0.26 0.75 0.63 0.77 0.36 0.45 0.48 0.47 0.46 0.46
Cytoplasm 0.64 0.55 0.7 0.75 0.79 0.84 0.82 0.83 0.78 0.72 0.69 0.68 0.81 0.81 0.83 0.17 0.23 0.17 0.19 0.13 0.12 0.19 0.21 0.22
Endoplasmic Reticulum 0.05 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.14 0.11 0.06 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.05 0.16 0.2 0.23 0.39 0.44 0.49 0.45 0 0 0 0.07 0.11 0.07 0 0 0 0.06 0.06 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 53 76 64 24 25 14 12 8 4 6 0 4 40 45 72 153 151 81 43 44 59 32 34 34
Bud 26 31 17 13 17 24 33 37 17 25 23 22 14 14 4 53 60 31 25 28 16 21 22 18
Bud Neck 2 0 6 0 0 2 1 7 0 0 1 3 15 10 15 1 0 0 29 34 32 25 26 26
Bud Site 4 2 3 0 0 2 2 1 0 3 0 3 1 0 0 2 3 0 – – – – – –
Cell Periphery 125 133 105 70 45 58 48 22 13 22 19 13 289 289 303 432 316 296 157 199 218 184 233 222
Cytoplasm 243 211 284 170 211 451 538 613 304 365 289 329 883 883 973 97 115 65 83 57 55 72 108 107
Endoplasmic Reticulum 20 27 11 7 1 0 1 1 1 2 1 1 13 15 25 30 16 10 58 50 26 14 21 19
Endosome 0 0 3 0 1 1 0 1 0 1 0 0 1 1 0 3 3 3 4 3 3 1 5 1
Golgi 1 0 1 0 0 0 0 0 0 0 0 0 1 1 0 0 0 3 2 1 0 1 2 1
Mitochondria 4 7 14 9 14 84 134 168 154 223 204 218 1 1 0 42 55 26 8 3 19 21 29 24
Nucleus 1 1 0 1 0 1 0 3 1 1 1 0 1 1 3 5 5 5 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 0 1 1 1 2 0 1 0 1 1 0 1 0 1 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 2 6 2 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0
SpindlePole 7 4 8 1 4 6 8 5 4 8 8 13 20 20 10 6 8 4 1 1 1 1 2 3
Vac/Vac Membrane 0 1 4 1 2 2 4 5 0 4 0 2 11 12 2 2 3 2 13 11 3 10 11 14
Unique Cell Count 377 387 405 228 268 538 655 738 392 504 418 486 1096 1093 1177 573 504 386 435 439 450 391 507 484
Labelled Cell Count 486 493 520 296 322 654 784 872 500 660 549 608 1291 1293 1407 828 735 527 435 439 450 391 507 484


Bud, Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 7.6 5.3 5.3 4.5 3.7 3.3 3.2 2.9 2.9 2.9 2.8 6.7 6.7 6.8 11.6 13.6 15.9 6.5 6.6 6.4
Std Deviation (1e-4) 2.1 2.4 1.6 2.2 1.6 1.7 1.3 1.0 1.0 1.0 1.2 0.8 1.6 1.6 1.6 3.1 4.0 4.4 1.9 2.1 1.7
Intensity Change (Log2) – – – 0.0 -0.23 -0.51 -0.66 -0.7 -0.83 -0.87 -0.84 -0.92 0.35 0.35 0.36 1.14 1.37 1.6 0.31 0.33 0.27

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -1.8 0 0 0 0 0 0 0 0 -8.2 -7.7 -6.0 4.0 5.0 1.9
Bud 0.9 0 0 0 0 0 0 0 0 -3.5 -3.5 -5.9 3.0 4.1 2.3
Bud Neck 0 0 0 0 0 0 0 0 0 -0.2 0 -0.3 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 1.3 0 0 0 0 0 0 0 0 0.2 0.2 -0.1 15.3 11.1 14.3
Cytoplasm 1.2 2.5 5.0 4.6 5.1 2.4 0.8 -0.3 -0.8 4.3 4.4 5.4 -16.8 -14.3 -15.1
Endoplasmic Reticulum 0.3 0 0 0 0 0 0 0 0 -2.1 -1.8 -0.7 1.9 0.4 -0.1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.3 0 0 0 0 0 0 0 0 0 0 0 2.6 4.2 2.1
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 -0.2 -0.2 0 -1.2 -0.4 -1.1
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.6757 7.6528 6.6058 7.3038 5.184 6.1283 7.6375 10.0756 8.477 8.8258 7.8913 8.6486 11.1609 12.7502 12.3781 12.9296 12.4284 11.9265
Actin 0.0636 0.0028 0.0027 0.0019 0.0674 0.0133 0.0101 0.0014 0.0086 0.0011 0.0026 0.002 0.0002 0.0044 0.0014 0.0002 0.0005 0.0014
Bud 0.0029 0.0013 0.002 0.0008 0.0053 0.0026 0.0011 0.0055 0.0037 0.0014 0.0007 0.0004 0.0002 0.0024 0.0009 0.0003 0.0004 0.0007
Bud Neck 0.0258 0.002 0.0084 0.007 0.0046 0.0054 0.0092 0.0012 0.0078 0.0279 0.0021 0.0048 0.0004 0.0007 0.0031 0.0011 0.0014 0.0019
Bud Periphery 0.035 0.0092 0.013 0.0148 0.026 0.025 0.012 0.0246 0.0292 0.0169 0.012 0.0107 0.0034 0.0191 0.0078 0.0081 0.0104 0.0188
Bud Site 0.0226 0.0915 0.08 0.0031 0.0209 0.0052 0.0113 0.0481 0.0241 0.0167 0.005 0.0007 0.0091 0.0468 0.0302 0.0005 0.0007 0.0012
Cell Periphery 0.5299 0.6144 0.6648 0.7738 0.5478 0.6045 0.6811 0.7566 0.7278 0.8546 0.8355 0.7523 0.901 0.8031 0.8739 0.9165 0.9254 0.9061
Cytoplasm 0.1518 0.2268 0.1457 0.1432 0.0922 0.2443 0.0809 0.1291 0.1436 0.0597 0.1161 0.1841 0.0391 0.0847 0.0567 0.0153 0.0297 0.0406
Cytoplasmic Foci 0.0092 0.0006 0.0051 0.0058 0.0093 0.0019 0.0154 0.0002 0.0036 0.0001 0.0004 0.0002 0 0.0001 0.0001 0 0.0001 0.0002
Eisosomes 0.005 0.0021 0.0031 0.0006 0.0124 0.0006 0.0034 0.0011 0.0012 0.0009 0.0042 0.0006 0.0033 0.0073 0.0014 0.0004 0.0008 0.0008
Endoplasmic Reticulum 0.0154 0.0161 0.0128 0.0162 0.0347 0.0124 0.022 0.0093 0.0106 0.0059 0.0071 0.0095 0.0317 0.0233 0.0154 0.0485 0.0184 0.0169
Endosome 0.0183 0.0002 0.0066 0.0146 0.0432 0.0044 0.0278 0.0001 0.0029 0 0.0004 0.0001 0 0 0 0 0.0001 0
Golgi 0.0069 0.0004 0.0014 0.003 0.055 0.0012 0.0074 0.0001 0.0019 0.0001 0.0006 0.0002 0.0001 0.0001 0.0001 0 0.0001 0.0001
Lipid Particles 0.0069 0.0014 0.0018 0.0015 0.006 0.0018 0.0108 0.0007 0.0029 0.0011 0.0022 0.0005 0.0005 0.0005 0.0004 0.0003 0.0005 0.0004
Mitochondria 0.003 0.0001 0.0024 0.0003 0.0457 0.0014 0.0243 0.0001 0.0059 0 0.0005 0.0131 0.0001 0.0002 0.0001 0 0.0002 0.0001
None 0.0451 0.0256 0.0352 0.0004 0.0056 0.0668 0.0517 0.0173 0.0146 0.0003 0.0016 0.0157 0.0009 0.0016 0.0019 0.0001 0.005 0.0045
Nuclear Periphery 0.0088 0.0008 0.0009 0.001 0.0071 0.0011 0.0054 0.0006 0.0007 0.0002 0.0004 0.0003 0.0018 0.0013 0.0009 0.0018 0.0007 0.0005
Nucleolus 0.0016 0.0001 0.0007 0.0001 0.0006 0.0004 0.0011 0.0001 0.0002 0.0002 0.0004 0 0 0.0001 0.0001 0 0.0001 0
Nucleus 0.0231 0.0004 0.0009 0.0004 0.0028 0.0015 0.0019 0.0002 0.0004 0.0004 0.0004 0.0001 0.0001 0.0002 0.0002 0.0001 0.0002 0.0001
Peroxisomes 0.002 0 0.0011 0.0001 0.0027 0.0002 0.0061 0 0.0066 0 0.0001 0.0001 0 0 0 0 0 0
Punctate Nuclear 0.0137 0.0001 0.0012 0.0001 0.0015 0.0009 0.0019 0 0.0002 0 0.0001 0 0 0 0 0 0 0
Vacuole 0.0085 0.0042 0.0095 0.0108 0.007 0.0049 0.0137 0.0036 0.0036 0.0121 0.0074 0.0046 0.0081 0.004 0.0055 0.0067 0.0051 0.0054
Vacuole Periphery 0.0009 0.0001 0.0008 0.0002 0.0021 0.0003 0.0015 0 0.0001 0 0.0001 0 0 0 0 0.0001 0.0001 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 63.772 95.9861 126.7111 166.471 83.8369 59.29 105.0943 107.845 122.1282 122.2766
Translational Efficiency 0.7557 0.8351 0.9735 0.63 0.8816 0.8183 0.7689 0.8102 0.7969 0.6864

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
180 770 871 15 1905 2076 115 197 2085 2846 986 212

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1211.75 823.65 2120.89 2351.49 678.88 871.30 2596.16 2339.78 724.88 858.41 2176.32 2340.61
Standard Deviation 259.59 163.85 397.24 559.09 104.40 165.92 460.91 499.63 195.38 166.71 432.95 504.08
Intensity Change Log 2 — -0.556989 0.807578 0.956483 — 0.360013 1.935151 1.785144 — -0.157624 1.319018 1.311111

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.015757 0.021356 0.002639 0.004582 0.004947 0.010967 0.001775 0.000328 0.005880 0.013778 0.002538 0.000629
Bud Neck 0.016550 0.068668 0.002703 0.005144 0.074908 0.085405 0.001278 0.000582 0.069870 0.080877 0.002537 0.000905
Bud Site 0.126001 0.202535 0.019510 0.088195 0.074712 0.116731 0.007724 0.008084 0.079140 0.139946 0.018135 0.013753
Cell Periphery 0.256911 0.152971 0.915465 0.760910 0.040224 0.237038 0.966726 0.975190 0.058931 0.214294 0.921444 0.960029
Cytoplasm 0.219104 0.338409 0.010136 0.025587 0.438095 0.400512 0.000465 0.001030 0.419189 0.383710 0.009008 0.002768
Cytoplasmic Foci 0.022187 0.077661 0.000262 0.022403 0.120996 0.029677 0.000292 0.000037 0.112465 0.042659 0.000266 0.001619
Eisosomes 0.003767 0.008171 0.001487 0.000652 0.009546 0.018106 0.001492 0.000737 0.009047 0.015418 0.001487 0.000731
Endoplasmic Reticulum 0.007728 0.011422 0.005161 0.000576 0.007055 0.010537 0.000359 0.000130 0.007113 0.010777 0.004601 0.000162
Endosome 0.019188 0.009267 0.000671 0.005851 0.007338 0.003516 0.000409 0.000045 0.008361 0.005072 0.000640 0.000456
Golgi 0.017012 0.007797 0.001718 0.008912 0.006584 0.005104 0.001089 0.000199 0.007485 0.005832 0.001645 0.000815
Lipid Particles 0.009618 0.005660 0.006043 0.013282 0.011951 0.004726 0.000151 0.000015 0.011750 0.004979 0.005355 0.000953
Mitochondria 0.002057 0.007648 0.000391 0.000171 0.008018 0.006362 0.000161 0.000099 0.007503 0.006710 0.000364 0.000104
Mitotic Spindle 0.000469 0.000558 0.000775 0.024205 0.000172 0.000347 0.000364 0.000212 0.000198 0.000404 0.000727 0.001910
None 0.000063 0.000607 0.000042 0.000012 0.001731 0.000576 0.000010 0.000006 0.001587 0.000585 0.000038 0.000006
Nuclear Periphery 0.000282 0.000097 0.001706 0.000419 0.000201 0.000129 0.000537 0.000247 0.000208 0.000121 0.001570 0.000259
Nuclear Periphery Foci 0.001855 0.000507 0.000512 0.001067 0.000268 0.000344 0.000078 0.000069 0.000405 0.000388 0.000461 0.000140
Nucleolus 0.000044 0.000203 0.000065 0.000047 0.000424 0.000134 0.000029 0.000018 0.000392 0.000152 0.000061 0.000020
Nucleus 0.003520 0.033686 0.000572 0.000196 0.141503 0.040631 0.000118 0.000044 0.129591 0.038752 0.000519 0.000055
Peroxisomes 0.002234 0.008748 0.000157 0.001354 0.007313 0.004945 0.000210 0.000003 0.006875 0.005974 0.000163 0.000098
Vacuole 0.268859 0.043099 0.026788 0.034590 0.043053 0.023402 0.015219 0.012108 0.062547 0.028731 0.025438 0.013698
Vacuole Periphery 0.006793 0.000928 0.003200 0.001845 0.000960 0.000810 0.001516 0.000819 0.001463 0.000842 0.003003 0.000891

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.76 4.73 3.05 5.43 -0.81 -5.83 2.01 10.06 11.20 0.97 -8.02 5.24 10.14 14.60 4.15
Bud Neck -10.94 6.83 3.56 12.73 -1.02 -2.50 23.23 23.66 28.39 1.44 -2.95 23.18 23.74 32.10 4.76
Bud Site -4.55 7.35 0.61 1.95 -1.21 -7.46 10.42 11.37 17.89 -0.05 -11.15 13.57 9.39 17.79 0.70
Cell Periphery 3.71 -26.86 -5.44 -6.67 1.71 -25.94 -94.52 -138.75 -80.51 -0.77 -22.74 -153.93 -91.08 -68.95 -3.84
Cytoplasm -6.02 11.62 8.41 18.31 -1.06 4.37 75.05 74.95 64.72 -2.33 4.51 69.80 71.68 72.05 3.59
Cytoplasmic Foci -7.75 4.39 -0.01 2.45 -1.00 21.73 31.40 31.53 17.28 1.02 17.11 31.31 28.33 16.55 -0.86
Eisosomes -3.63 2.28 3.14 10.17 3.08 -7.52 9.95 11.68 19.58 2.15 -6.70 10.70 11.96 21.42 3.42
Endoplasmic Reticulum -1.39 1.32 4.02 5.39 6.30 -3.01 9.39 9.76 11.26 2.92 -3.38 2.71 10.44 12.28 7.10
Endosome 1.69 3.28 1.64 0.60 -0.93 6.20 10.61 12.75 15.07 1.15 4.16 10.80 9.66 8.95 0.46
Golgi 1.47 2.53 0.74 -0.14 -0.87 1.66 5.62 9.99 8.22 1.21 1.70 7.38 6.78 6.31 1.36
Lipid Particles 1.93 1.46 -0.33 -0.65 -0.62 8.90 15.34 15.55 17.55 2.42 8.86 4.46 9.84 4.66 2.94
Mitochondria -2.75 1.26 1.43 4.61 1.62 1.86 13.04 13.22 9.70 0.61 0.91 12.76 13.21 10.27 3.77
Mitotic Spindle -0.39 -2.32 -1.00 -0.99 -0.98 -2.46 -1.73 -1.20 1.95 1.39 -2.51 -12.22 -1.02 -0.89 -0.70
None -2.27 0.69 1.77 2.49 4.34 4.54 7.11 7.13 7.27 1.75 4.22 6.99 7.14 6.69 6.14
Nuclear Periphery 1.97 -10.99 -1.00 -3.21 9.58 5.44 -4.51 -1.04 -2.93 3.49 6.10 -16.46 -1.21 -3.63 14.61
Nuclear Periphery Foci 5.58 5.69 1.02 -0.70 -0.71 -3.01 8.12 9.82 15.68 0.50 0.62 -1.23 4.25 4.19 5.08
Nucleolus -4.02 -2.42 -0.10 3.86 1.34 6.23 8.47 8.72 19.47 4.04 5.35 7.75 8.71 11.07 13.48
Nucleus -9.65 4.45 4.95 11.27 3.86 22.36 34.40 34.42 21.78 2.07 21.81 33.54 33.66 24.48 6.33
Peroxisomes -5.47 3.77 0.59 4.41 -0.94 3.68 12.52 13.83 13.63 1.01 1.40 13.77 13.69 14.50 0.66
Vacuole 9.36 10.10 7.62 0.46 -0.39 10.28 7.93 7.43 2.85 0.63 10.81 11.61 10.21 3.81 2.87
Vacuole Periphery 2.04 1.22 1.69 -2.19 3.10 0.73 -2.85 0.90 -0.05 3.90 2.07 -5.20 1.96 -0.33 12.77
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Amino acid transporter for valine, leucine, isoleucine, and tyrosine; low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cell periphery (20%), cytoplasm (11%), mixed (22%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Tat1

Tat1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tat1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available