Standard name
Human Ortholog
Description Putative mitochondrial inner membrane transporter; proposed role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; YMC2 has a paralog, YMC1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Bud 0 0 0.09 0.05 0.05 0.05 0.05 0.06 – 0.05 0.07 0.06 0 0 0 0.07 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0.08 0.08 0.12 – 0.12 0.15 0.09 0 0 0 0.12 0.14 0.17 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.07 0 0 0 0 0 0 0 – 0 0 0 0 0.06 0.15 0.07 0.19 0.09 0.09 0.05 0.07 0 0.08 0.06
Golgi 0 0.1 0 0 0 0 0 0 – 0 0 0 0.17 0.28 0.31 0.37 0.21 0.23 0.07 0.08 0 0.05 0.12 0.11
Mitochondria 0.89 0.82 0.96 0.94 0.93 0.89 0.91 0.81 – 0.84 0.85 0.92 0.86 0.61 0.52 0.09 0.07 0.11 0.69 0.74 0.78 0.73 0.58 0.6
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleolus 0.07 0 0.05 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0.06 0.11 0.07 0.12 0.06 0 0 0 0.06 0.07 0.07
SpindlePole 0 0 0 0 0 0.07 0.08 0.12 – 0.13 0.07 0.07 0 0 0 0.08 0.08 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0.11 0.19 0 0.06 0.09 0.05 0 0 – 0 0 0 0.14 0.25 0.12 0.09 0.14 0.25 0 0 0 0.05 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 1 1 0 0 – 0 0 0 1 2 1 3 1 5 1 1 1 2 5 12
Bud 3 1 12 14 23 24 31 40 – 34 24 36 1 2 4 7 4 2 0 0 0 0 2 1
Bud Neck 0 0 0 0 0 0 1 3 – 2 1 2 0 0 0 0 0 0 0 0 0 0 0 2
Bud Site 0 1 0 0 2 16 16 9 – 14 7 16 0 0 0 2 2 1 – – – – – –
Cell Periphery 0 4 1 11 2 5 0 1 – 3 0 4 1 6 6 3 6 10 0 0 0 0 0 0
Cytoplasm 2 4 5 11 23 43 52 84 – 76 51 52 0 4 7 13 23 22 0 0 0 0 3 0
Endoplasmic Reticulum 0 1 1 1 4 4 1 1 – 1 0 1 2 1 3 2 5 4 0 0 1 1 2 1
Endosome 9 2 1 5 9 2 0 7 – 5 0 0 0 11 30 8 31 11 12 5 9 5 16 14
Golgi 1 11 0 2 1 0 0 0 – 1 0 0 11 48 64 40 34 29 10 9 1 6 25 28
Mitochondria 111 90 133 292 420 468 567 558 – 542 289 515 55 105 106 10 11 14 99 89 108 103 126 155
Nucleus 0 0 1 0 6 21 14 24 – 11 8 6 1 0 2 5 4 1 0 0 0 0 1 0
Nuclear Periphery 2 4 0 2 13 3 2 2 – 1 2 2 0 1 1 5 6 2 2 0 5 1 0 2
Nucleolus 9 4 7 6 10 11 2 7 – 4 2 6 2 3 4 3 7 3 2 1 0 1 1 1
Peroxisomes 1 1 1 12 6 9 8 11 – 19 0 2 0 11 23 7 19 7 4 1 5 8 16 18
SpindlePole 2 0 2 4 12 35 47 82 – 82 23 37 1 1 9 9 12 10 3 0 0 0 2 0
Vac/Vac Membrane 14 21 3 18 39 24 24 12 – 23 7 3 9 42 24 10 23 31 2 4 1 6 8 15
Unique Cell Count 125 110 139 309 453 528 626 693 645 340 557 64 171 205 107 159 126 143 120 138 141 219 259
Labelled Cell Count 154 145 167 378 571 666 765 841 818 414 682 84 237 284 127 188 152 143 120 138 141 219 259


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.6 7.7 4.6 5.3 4.7 3.9 3.1 3.4 – 3.0 2.9 2.9 7.9 8.2 7.8 7.7 7.8 8.1 8.3 8.7 8.5
Std Deviation (1e-4) 1.3 1.7 1.1 1.4 1.2 1.5 1.3 1.5 – 1.3 1.3 1.0 1.1 1.5 1.5 1.5 1.5 1.5 1.3 3.4 1.4
Intensity Change (Log2) – – – 0.2 0.03 -0.22 -0.55 -0.45 – -0.59 -0.64 -0.67 0.78 0.83 0.77 0.74 0.76 0.82 0.85 0.93 0.9

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud -1.7 0 0 0 0 – 0 0 0 0 -3.1 -2.9 -0.6 -2.3 -2.6
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 2.9
Cytoplasm 0 0.7 1.8 1.9 3.0 – 2.9 3.5 2.2 0 0 0 2.6 3.2 3.7
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 – 0 0 0 0 2.6 4.4 0 5.2 3.1
Golgi 0 0 0 0 0 – 0 0 0 0 6.8 7.3 7.9 5.8 6.0
Mitochondria -0.5 0 0 0 0 – 0 0 0 -2.5 -7.1 -8.7 -13.6 -15.3 -13.8
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 -0.3 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 2.6 3.8 0 3.9 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 2.5 2.5
Vacuole 1.7 2.6 1.3 0 0 – 0 0 0 0 5.6 3.2 2.5 3.8 5.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.4118 9.6874 8.6209 7.9333 7.8033 9.3509 8.8543 9.7925 9.0932 8.8315 7.7684 9.1059 9.6551 9.8454 9.4239 9.8735 8.492 9.0853
Actin 0.0204 0.0082 0.0231 0.0025 0.0017 0.0016 0.0023 0.0024 0.0045 0.0019 0.0007 0.0007 0.0076 0.0029 0.0016 0.001 0.0057 0.0028
Bud 0.0004 0.0068 0.003 0.0008 0.0233 0.0018 0.0001 0.0008 0.0006 0.0001 0.0001 0.0001 0.0001 0.0002 0.0006 0.0001 0.0034 0.0001
Bud Neck 0.0007 0.0021 0.0005 0.0138 0.0003 0.001 0.0003 0.0004 0.0002 0.001 0 0.0001 0.0001 0.0002 0.0001 0.0001 0 0.0001
Bud Periphery 0.0008 0.0078 0.0055 0.0014 0.0457 0.0007 0.0002 0.0013 0.0022 0.0002 0.0002 0.0007 0.0002 0.0004 0.0006 0.0002 0.0101 0.0002
Bud Site 0.0024 0.0234 0.0048 0.0037 0.0047 0.0003 0.0042 0.0027 0.0019 0.0002 0.0003 0.0001 0.0007 0.0012 0.0012 0.0003 0.0004 0.0001
Cell Periphery 0.0006 0.0023 0.0012 0.0006 0.001 0.0003 0.0002 0.0005 0.0005 0.0002 0.0001 0.0003 0.0002 0.0004 0.0003 0.0003 0.0001 0.0001
Cytoplasm 0.0026 0.0004 0.0011 0.0065 0.0031 0.0021 0.0009 0.0002 0.001 0.0001 0 0 0.0001 0.0001 0.0008 0 0.0003 0
Cytoplasmic Foci 0.0197 0.0037 0.0125 0.0215 0.0078 0.0024 0.0078 0.0121 0.0052 0.0044 0.0051 0.0013 0.0053 0.0074 0.0025 0.0035 0.0012 0.001
Eisosomes 0.0003 0.0003 0.0003 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0005 0.0001
Endoplasmic Reticulum 0.0033 0.0002 0.0007 0.001 0.0016 0.0001 0.0007 0.0001 0.0007 0 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0009 0
Endosome 0.0479 0.0249 0.0319 0.0184 0.0322 0.01 0.0101 0.0257 0.0107 0.0101 0.0069 0.0043 0.0106 0.0168 0.0107 0.0054 0.0073 0.004
Golgi 0.0273 0.0231 0.0291 0.0085 0.0195 0.0105 0.0128 0.0566 0.0152 0.0476 0.0099 0.0178 0.0151 0.0488 0.0132 0.0118 0.0126 0.0149
Lipid Particles 0.0453 0.0082 0.0234 0.0089 0.0148 0.0093 0.0362 0.0152 0.0154 0.0072 0.0087 0.0085 0.034 0.0274 0.009 0.0142 0.0127 0.0127
Mitochondria 0.7604 0.795 0.7842 0.8888 0.7997 0.9361 0.8792 0.8176 0.902 0.9152 0.9287 0.9496 0.8845 0.8461 0.926 0.9221 0.9195 0.9542
None 0.0049 0.0001 0.0026 0.0002 0.0006 0.0002 0.0059 0.0001 0.0006 0 0.0001 0 0.0003 0 0 0 0.0038 0
Nuclear Periphery 0.0109 0.0003 0.0018 0.0004 0.0004 0.0001 0.0044 0.0001 0.0032 0 0.0007 0.0001 0.0004 0.0001 0.0002 0.0004 0.0084 0.0001
Nucleolus 0.002 0.0091 0.0039 0.0003 0.0033 0.0012 0.0019 0.003 0.0005 0.0001 0.0002 0.0002 0.0009 0.0071 0.0003 0.0012 0.0003 0.0001
Nucleus 0.0043 0.0024 0.0023 0.0003 0.001 0.0043 0.0014 0.0004 0.0006 0.0001 0.0001 0.0001 0.0002 0.0006 0.0002 0.0002 0.0005 0
Peroxisomes 0.0179 0.0101 0.0305 0.0155 0.0145 0.0036 0.0162 0.0442 0.0168 0.009 0.0297 0.0049 0.018 0.0174 0.0118 0.0119 0.0084 0.0041
Punctate Nuclear 0.0029 0.0001 0.0016 0.0007 0.0001 0.0001 0.003 0.0001 0.0017 0 0.0001 0 0.0006 0.0001 0 0.0009 0.0013 0
Vacuole 0.0125 0.0391 0.0191 0.0025 0.0137 0.0072 0.0031 0.0105 0.0062 0.0009 0.0015 0.0048 0.007 0.0116 0.0083 0.015 0.0006 0.0011
Vacuole Periphery 0.0127 0.0324 0.0168 0.0035 0.011 0.007 0.0089 0.0062 0.0102 0.0014 0.0066 0.0062 0.0138 0.0109 0.0123 0.011 0.0019 0.0045

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 36.2229 28.8938 29.5731 21.2782 32.5139 28.9623 33.496 19.3779 20.0527 34.842
Translational Efficiency 2.297 1.8011 1.1526 1.3606 1.8048 2.3781 1.388 1.7219 1.3003 1.3106

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2220 1635 1163 1142 1720 1163 2831 2298 3940 2798 3994 3440

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 752.23 937.56 842.08 873.20 839.73 1015.43 942.95 876.82 790.43 969.93 913.58 875.62
Standard Deviation 101.15 163.09 117.33 124.51 140.68 166.89 130.80 125.94 127.62 169.10 135.04 125.48
Intensity Change Log 2 — 0.317737 0.162783 0.215138 — 0.274093 0.167256 0.062355 — 0.294880 0.165144 0.136567

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000575 0.002165 0.003586 0.023317 0.000632 0.001817 0.000996 0.000380 0.000600 0.002020 0.001750 0.007995
Bud Neck 0.003947 0.002858 0.006289 0.016104 0.004135 0.003765 0.003837 0.008194 0.004029 0.003235 0.004551 0.010820
Bud Site 0.011827 0.011196 0.038566 0.135703 0.009836 0.008389 0.024854 0.026084 0.010958 0.010029 0.028847 0.062475
Cell Periphery 0.000416 0.000405 0.000201 0.000528 0.000512 0.000287 0.000330 0.000778 0.000458 0.000356 0.000292 0.000695
Cytoplasm 0.005274 0.002217 0.023959 0.044356 0.001801 0.001915 0.005836 0.005171 0.003758 0.002092 0.011114 0.018180
Cytoplasmic Foci 0.036290 0.037679 0.167606 0.105841 0.020403 0.054633 0.016008 0.016452 0.029354 0.044726 0.060152 0.046127
Eisosomes 0.000059 0.000072 0.000084 0.000183 0.000051 0.000074 0.000044 0.000060 0.000055 0.000073 0.000056 0.000101
Endoplasmic Reticulum 0.000796 0.000761 0.002461 0.003153 0.000327 0.000510 0.000278 0.000416 0.000591 0.000656 0.000913 0.001325
Endosome 0.088999 0.068997 0.120642 0.075718 0.069701 0.082761 0.046631 0.083924 0.080574 0.074718 0.068182 0.081200
Golgi 0.097304 0.063329 0.169584 0.087281 0.043130 0.071665 0.044927 0.035946 0.073655 0.066794 0.081225 0.052988
Lipid Particles 0.004363 0.005217 0.004413 0.002441 0.003016 0.007217 0.000356 0.000729 0.003775 0.006048 0.001537 0.001297
Mitochondria 0.661080 0.724418 0.182352 0.220921 0.781292 0.687679 0.755543 0.715978 0.713558 0.709148 0.588637 0.551631
Mitotic Spindle 0.008060 0.012839 0.123911 0.091809 0.006729 0.013567 0.043152 0.017982 0.007479 0.013142 0.066668 0.042490
None 0.001125 0.000420 0.000569 0.001075 0.000422 0.000357 0.000396 0.000697 0.000819 0.000394 0.000447 0.000822
Nuclear Periphery 0.000434 0.000256 0.000767 0.000509 0.000138 0.000378 0.000208 0.000112 0.000305 0.000306 0.000371 0.000244
Nuclear Periphery Foci 0.000524 0.000643 0.001665 0.000811 0.000632 0.000933 0.000157 0.000261 0.000571 0.000764 0.000596 0.000444
Nucleolus 0.000766 0.001264 0.002213 0.001071 0.000559 0.000746 0.000324 0.001004 0.000676 0.001048 0.000874 0.001026
Nucleus 0.001173 0.001751 0.006484 0.005446 0.000790 0.001198 0.000580 0.000999 0.001006 0.001521 0.002299 0.002476
Peroxisomes 0.013619 0.023128 0.028953 0.104434 0.022838 0.027158 0.012214 0.020759 0.017644 0.024803 0.017088 0.048537
Vacuole 0.028301 0.020219 0.072521 0.067569 0.015769 0.019381 0.023561 0.037462 0.022830 0.019871 0.037817 0.047457
Vacuole Periphery 0.035067 0.020166 0.043173 0.011731 0.017285 0.015571 0.019768 0.026612 0.027304 0.018256 0.026584 0.021672

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.87 -4.85 -9.19 -8.49 -7.69 -3.91 -2.19 2.67 4.88 4.13 -6.25 -5.05 -8.72 -6.84 -7.14
Bud Neck 2.01 -3.56 -10.91 -12.32 -8.57 0.34 0.31 -3.51 -4.06 -4.77 1.44 -1.07 -8.78 -10.34 -8.75
Bud Site 0.37 -9.63 -20.64 -20.69 -14.91 0.89 -7.51 -7.58 -8.38 -0.47 0.79 -11.26 -19.87 -20.16 -11.70
Cell Periphery 0.17 3.30 -0.98 -1.19 -3.56 2.99 2.33 -2.47 -5.85 -5.17 2.05 3.31 -3.13 -5.15 -6.11
Cytoplasm 4.22 -8.29 -13.79 -15.03 -6.50 -0.17 -6.73 -4.50 -4.43 0.87 3.74 -8.81 -12.84 -14.75 -6.08
Cytoplasmic Foci -0.50 -27.89 -16.93 -15.87 10.57 -10.75 2.89 2.40 12.38 -0.40 -7.95 -14.96 -8.81 -0.53 5.87
Eisosomes -2.65 -3.13 -12.92 -11.98 -8.39 -5.42 2.38 -2.83 3.07 -5.54 -5.21 -0.22 -10.63 -6.61 -10.48
Endoplasmic Reticulum 0.26 -6.05 -4.97 -5.00 -1.43 -2.37 0.72 -1.61 1.31 -2.11 -0.80 -3.35 -4.47 -4.00 -2.35
Endosome 4.71 -6.32 3.61 -0.99 9.43 -2.55 6.14 -3.12 -0.23 -10.55 1.78 4.41 0.06 -1.70 -4.28
Golgi 7.92 -11.08 2.86 -4.03 12.66 -6.69 -0.60 2.54 9.02 3.54 2.22 -2.28 8.02 5.46 10.22
Lipid Particles -0.84 -0.20 2.29 2.78 2.28 -2.98 4.12 3.54 5.15 -2.71 -2.74 4.54 5.18 6.50 0.66
Mitochondria -6.02 47.86 41.57 43.79 -2.55 7.32 2.78 6.37 -2.26 4.27 0.53 15.59 19.46 17.24 4.32
Mitotic Spindle -3.43 -19.36 -16.10 -14.88 4.07 -3.63 -15.46 -7.03 -2.07 9.87 -5.00 -24.12 -16.75 -13.03 7.76
None 2.23 1.72 -0.09 -1.26 -1.00 0.92 0.40 -3.60 -6.97 -7.28 2.34 2.05 -0.13 -2.24 -1.98
Nuclear Periphery 1.22 -1.83 -0.65 -2.04 1.11 -3.71 -1.14 0.96 4.29 1.65 -0.02 -0.72 0.45 0.72 1.52
Nuclear Periphery Foci -0.80 -4.29 -2.27 -1.86 1.42 -1.03 2.24 1.76 3.54 -3.02 -1.27 -0.32 0.03 1.41 0.39
Nucleolus -1.31 -2.72 -0.76 0.29 1.76 -0.76 1.17 -1.19 -0.65 -1.97 -1.53 -1.06 -1.25 0.04 -0.44
Nucleus -0.85 -5.37 -5.51 -4.47 -0.04 -0.67 0.48 -0.47 0.35 -1.18 -1.10 -3.59 -4.54 -2.72 -1.05
Peroxisomes -4.51 -5.81 -15.90 -13.86 -12.28 -1.45 4.99 0.85 2.37 -4.99 -4.07 0.34 -12.47 -8.95 -13.02
Vacuole 4.32 -12.56 -11.00 -12.57 -1.57 -1.97 -5.17 -10.88 -8.11 -6.86 2.22 -9.89 -13.74 -14.75 -6.00
Vacuole Periphery 7.39 -2.65 13.89 5.55 11.82 0.96 -1.49 -5.26 -6.42 -4.27 6.51 0.55 4.33 -2.52 3.64
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative mitochondrial inner membrane transporter; proposed role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; YMC2 has a paralog, YMC1, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (95%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Ymc2

Ymc2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ymc2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available