Standard name
Human Ortholog
Description Mannosyltransferase; involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability; human homolog ALG1 complements yeast null mutant
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.06 0.11 0 0 0 0 – 0 0.05 0 0 0.05 0 0.06 0.08 0.09 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.06 0.07 0.09 0.09 0.05 0.05 – 0.06 0.06 0.07 0.12 0.12 0.15 0.23 0.16 0.26 0 0 0 0 0 0
Cytoplasm 0.38 0.23 0.07 0.2 0.25 0.19 0.17 0.18 – 0.25 0.22 0.17 0.17 0.17 0.23 0.6 0.58 0.51 0 0.07 0 0 0 0
Endoplasmic Reticulum 0.46 0.75 0.88 0.67 0.51 0.55 0.5 0.5 – 0.39 0.39 0.42 0.77 0.77 0.71 0 0 0 0.8 0.83 0.9 0.85 0.84 0.79
Endosome 0 0 0 0 0.08 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.14 0 0.06 0.15 0.08 0.23 0.22 0.2 – 0.32 0.42 0.41 0 0 0 0.12 0.13 0.07 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0.06 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0 0 0 0.18 0.14 0.23 0.22 – 0.17 0.1 0.13 0 0 0.07 0.09 0.06 0.09 0.05 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 3 24 28 13 12 10 30 – 7 25 18 14 19 13 6 11 11 1 1 10 10 12 15
Bud 1 4 2 2 1 2 7 9 – 11 15 8 0 0 0 2 2 3 0 0 1 1 3 2
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 0 1 0 3 5
Bud Site 0 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 7 25 18 35 29 27 36 – 34 29 40 46 46 68 24 22 30 0 0 9 9 17 25
Cytoplasm 14 50 26 51 94 64 86 124 – 138 108 101 68 68 104 62 80 59 4 15 2 5 19 23
Endoplasmic Reticulum 17 160 340 173 195 188 254 346 – 216 190 246 305 304 326 1 1 2 78 186 387 320 522 539
Endosome 1 1 0 6 31 9 8 10 – 8 1 6 1 1 0 1 3 0 0 1 1 1 1 2
Golgi 0 0 1 1 1 1 1 1 – 0 0 0 0 0 2 0 1 2 0 0 0 1 2 5
Mitochondria 5 5 25 39 30 77 112 137 – 178 205 237 1 1 1 12 18 8 3 4 7 10 22 23
Nucleus 0 0 1 0 0 2 1 2 – 4 2 2 0 0 0 1 5 1 0 0 0 0 0 0
Nuclear Periphery 1 0 7 2 1 4 17 18 – 31 19 29 0 0 0 0 2 1 1 2 1 0 1 1
Nucleolus 0 0 0 0 0 0 1 0 – 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
Peroxisomes 0 0 0 0 2 0 1 0 – 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 0 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Vac/Vac Membrane 2 3 6 6 69 49 119 150 – 93 50 74 11 11 30 9 9 10 4 8 3 7 16 27
Unique Cell Count 37 213 388 257 382 340 513 693 554 492 584 394 393 461 104 139 116 98 223 430 376 625 681
Labelled Cell Count 43 233 458 326 472 437 644 864 720 645 762 446 450 544 118 154 127 98 223 430 376 625 681


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.4 8.6 8.0 7.8 8.2 7.3 7.2 7.6 – 6.9 6.8 6.7 9.5 9.5 11.6 6.7 7.7 9.5 9.5 9.6 9.8
Std Deviation (1e-4) 0.9 1.4 1.1 1.2 1.2 1.4 1.3 1.2 – 1.3 1.1 1.2 1.1 1.1 1.5 1.1 1.4 1.6 1.4 1.6 1.4
Intensity Change (Log2) – – – -0.02 0.03 -0.13 -0.14 -0.06 – -0.21 -0.23 -0.25 0.26 0.26 0.54 -0.24 -0.05 0.25 0.26 0.28 0.3

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 2.2 -1.8 -1.6 -3.3 -1.3 – -4.2 -0.7 -2.3 -1.7 -0.8 -2.4 -0.2 0.7 1.2
Bud 0 0 0 0 0 – 1.9 2.7 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0.3 1.4 1.1 -0.8 -0.9 – -0.2 -0.3 0.2 2.5 2.6 3.9 5.0 3.3 5.9
Cytoplasm 5.0 6.8 5.0 4.5 5.1 – 7.3 6.3 4.8 4.5 4.6 6.4 12.5 12.8 11.1
Endoplasmic Reticulum -6.3 -11.0 -9.8 -12.0 -12.3 – -14.9 -14.7 -14.2 -3.8 -3.8 -6.0 -17.0 -18.4 -17.4
Endosome 0 5.7 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 3.6 0.8 6.3 6.4 5.9 – 9.4 11.8 11.7 -4.8 -4.8 -5.2 1.7 2.4 0.2
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 -0.7 1.4 0.8 – 2.9 1.8 2.6 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 0 7.7 6.6 9.3 9.0 – 7.5 5.2 6.2 1.2 1.2 3.6 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.4374 5.4711 5.6031 5.1472 4.5353 5.3338 5.3601 6.1863 5.7858 5.6712 5.6224 5.8881 5.9537 6.8256 6.5064 6.1089 6.2329 6.3435
Actin 0.0041 0.0013 0.0173 0.0004 0.0181 0.0012 0.0314 0.0036 0.0028 0.0083 0.0003 0.0086 0.0021 0.0049 0.0035 0.0069 0.0079 0.0012
Bud 0.0006 0.0001 0.0007 0.0001 0.0016 0 0.0005 0.0004 0.0001 0.0003 0 0 0 0.0002 0.0001 0.0001 0.0001 0
Bud Neck 0.0007 0.0005 0.0018 0.0042 0.0058 0.0006 0.0016 0.0007 0.0006 0.0093 0.0007 0.0049 0.0001 0.001 0.0005 0.0028 0.0029 0.0049
Bud Periphery 0.0006 0.0002 0.0019 0.0003 0.0027 0.0001 0.0012 0.0004 0.0002 0.0013 0.0001 0.0001 0 0.0003 0.0003 0.0002 0.0001 0.0001
Bud Site 0.0005 0.0054 0.0039 0.0006 0.0048 0 0.0027 0.0126 0.0008 0.0013 0.0001 0.0001 0.0001 0.0028 0.0011 0.0003 0.0001 0.0001
Cell Periphery 0.0012 0.0044 0.0052 0.0056 0.0033 0.001 0.0028 0.004 0.0039 0.0051 0.0006 0.0046 0.0012 0.0039 0.0032 0.003 0.0016 0.0007
Cytoplasm 0.2057 0.2503 0.1774 0.2517 0.1764 0.1455 0.1313 0.2799 0.2155 0.1248 0.0939 0.1628 0.0846 0.2032 0.1448 0.1769 0.1902 0.1121
Cytoplasmic Foci 0.0091 0.0054 0.0078 0.0013 0.0512 0.0016 0.0128 0.014 0.0067 0.0367 0.0022 0.0036 0.0033 0.0033 0.0051 0.0039 0.0061 0.0054
Eisosomes 0 0.0001 0.0001 0 0.0001 0 0.0003 0.0004 0.0004 0.0004 0 0.0008 0.0001 0.0001 0 0.0001 0 0
Endoplasmic Reticulum 0.6853 0.6691 0.7294 0.6967 0.5427 0.8149 0.6762 0.5786 0.7236 0.6979 0.868 0.7638 0.8695 0.7424 0.7936 0.7506 0.7568 0.8469
Endosome 0.0349 0.0123 0.0166 0.0019 0.0466 0.0091 0.0385 0.0405 0.0121 0.032 0.0141 0.0099 0.007 0.0055 0.0101 0.0228 0.0146 0.0081
Golgi 0.0011 0.0017 0.0065 0.0002 0.0179 0.001 0.0078 0.0036 0.0021 0.0154 0.0004 0.0023 0.0013 0.0028 0.0025 0.0058 0.004 0.001
Lipid Particles 0.0056 0.0119 0.0114 0.0018 0.0112 0.0029 0.0185 0.0101 0.005 0.015 0.0012 0.0088 0.0114 0.0119 0.0189 0.008 0.0049 0.0069
Mitochondria 0.0003 0.0002 0.0009 0.0001 0.0248 0.0004 0.0031 0.0006 0.0004 0.0018 0.0002 0.0007 0.0001 0.0002 0.0001 0.0012 0.0003 0.0001
None 0.0109 0.0093 0.0034 0.0225 0.009 0.0033 0.0324 0.019 0.0122 0.0134 0.0006 0.0107 0.0044 0.0012 0.0057 0.001 0.001 0.0011
Nuclear Periphery 0.0223 0.0129 0.0074 0.0043 0.0057 0.0119 0.0187 0.0138 0.0071 0.0068 0.0086 0.0099 0.0103 0.0063 0.0049 0.0099 0.0056 0.0055
Nucleolus 0.0004 0.0002 0.0001 0 0.0004 0 0.0005 0.0004 0 0.0003 0 0.0001 0 0.0001 0 0.0001 0 0
Nucleus 0.0046 0.003 0.0014 0.0027 0.0036 0.002 0.004 0.0065 0.0011 0.002 0.0026 0.0018 0.0013 0.0041 0.0007 0.0013 0.0009 0.0026
Peroxisomes 0.0002 0.0001 0.0005 0 0.0473 0 0.0023 0.0003 0.0013 0.02 0 0.0006 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001
Punctate Nuclear 0.003 0.0007 0.0008 0.0001 0.0148 0.0002 0.0026 0.0019 0.0003 0.0034 0.0003 0.001 0.0003 0.0005 0.0003 0.0007 0.0004 0.0004
Vacuole 0.0081 0.0106 0.0049 0.0053 0.01 0.0039 0.009 0.008 0.0036 0.0041 0.0055 0.0042 0.0025 0.0053 0.0041 0.0035 0.0022 0.0025
Vacuole Periphery 0.0009 0.0004 0.0004 0.0002 0.002 0.0004 0.0019 0.0008 0.0003 0.0005 0.0005 0.0005 0.0003 0.0002 0.0002 0.0007 0.0003 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 23.7028 24.8421 24.94 33.264 18.0151 22.8728 33.6135 40.8862 33.3148 38.6303
Translational Efficiency 1.0269 0.6987 0.7175 0.5439 0.9193 1.1059 0.7519 0.5073 0.7307 0.6453

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
108 924 288 1536 1636 1079 2160 1758 1744 2003 2448 3294

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1100.49 1001.00 1353.24 1132.25 931.89 959.84 1078.43 1127.37 942.33 978.83 1110.76 1129.65
Standard Deviation 158.22 175.19 159.26 144.56 153.93 128.22 146.04 153.56 159.46 153.09 172.17 149.45
Intensity Change Log 2 — -0.136704 0.298272 0.041047 — 0.042634 0.210701 0.274730 — -0.051698 0.258777 0.152910

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002907 0.002738 0.005691 0.010397 0.001125 0.000398 0.004932 0.011062 0.001235 0.001477 0.005021 0.010752
Bud Neck 0.003529 0.001547 0.003233 0.011328 0.000780 0.000793 0.004261 0.009958 0.000950 0.001141 0.004140 0.010597
Bud Site 0.018427 0.010355 0.011637 0.044759 0.007435 0.002222 0.011628 0.038512 0.008116 0.005974 0.011629 0.041425
Cell Periphery 0.003766 0.004708 0.004279 0.010211 0.007704 0.003539 0.007424 0.007388 0.007460 0.004078 0.007054 0.008704
Cytoplasm 0.086041 0.073891 0.029696 0.135976 0.041968 0.094177 0.134269 0.149761 0.044697 0.084819 0.121966 0.143333
Cytoplasmic Foci 0.043364 0.021707 0.005262 0.033226 0.012615 0.015924 0.009718 0.034567 0.014519 0.018592 0.009194 0.033941
Eisosomes 0.000781 0.000623 0.000174 0.002001 0.000570 0.000763 0.001916 0.002175 0.000583 0.000699 0.001711 0.002094
Endoplasmic Reticulum 0.539077 0.805234 0.830292 0.512067 0.878851 0.809561 0.746638 0.517072 0.857810 0.807565 0.756480 0.514738
Endosome 0.016406 0.012057 0.011643 0.022753 0.004470 0.005987 0.005511 0.024434 0.005209 0.008787 0.006232 0.023650
Golgi 0.008044 0.011014 0.001488 0.015865 0.008521 0.014302 0.007105 0.013823 0.008492 0.012785 0.006444 0.014775
Lipid Particles 0.028039 0.019413 0.015415 0.067865 0.008521 0.022636 0.031019 0.087231 0.009730 0.021149 0.029184 0.078200
Mitochondria 0.001702 0.002596 0.000098 0.003361 0.007175 0.005399 0.003731 0.003499 0.006836 0.004106 0.003304 0.003435
Mitotic Spindle 0.003179 0.000359 0.000222 0.009530 0.000140 0.000616 0.000120 0.003657 0.000328 0.000498 0.000132 0.006396
None 0.000015 0.002568 0.000299 0.000910 0.004299 0.002235 0.007282 0.001852 0.004034 0.002388 0.006460 0.001412
Nuclear Periphery 0.001607 0.001587 0.003334 0.001044 0.000547 0.000653 0.000183 0.001828 0.000613 0.001084 0.000554 0.001463
Nuclear Periphery Foci 0.024419 0.011340 0.042968 0.018069 0.002171 0.004280 0.002715 0.016751 0.003549 0.007537 0.007451 0.017365
Nucleolus 0.000043 0.000114 0.000006 0.000155 0.000054 0.000088 0.000116 0.000200 0.000053 0.000100 0.000103 0.000179
Nucleus 0.007972 0.003571 0.001936 0.013870 0.001230 0.004401 0.007358 0.015494 0.001647 0.004018 0.006720 0.014737
Peroxisomes 0.001011 0.001884 0.000138 0.003530 0.007034 0.002432 0.004903 0.004460 0.006661 0.002179 0.004343 0.004026
Vacuole 0.195013 0.010113 0.031888 0.080051 0.002637 0.007711 0.008741 0.054454 0.014550 0.008819 0.011464 0.066390
Vacuole Periphery 0.014657 0.002581 0.000300 0.003033 0.002152 0.001882 0.000427 0.001824 0.002926 0.002204 0.000412 0.002387

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.15 -1.03 -5.81 -6.35 -1.68 3.70 -5.20 -10.27 -11.21 -5.12 -0.63 -5.27 -13.57 -12.25 -5.84
Bud Neck 2.78 0.26 -7.45 -10.69 -7.79 -0.06 -5.28 -11.30 -11.37 -5.81 -0.75 -5.41 -15.71 -15.59 -8.39
Bud Site 1.20 0.97 -2.80 -9.99 -7.70 4.65 -2.84 -10.96 -13.49 -9.36 1.64 -2.31 -14.67 -16.45 -13.27
Cell Periphery -0.73 -0.35 -4.54 -3.95 -3.50 3.79 0.26 0.47 -4.29 0.31 3.26 0.40 -0.86 -5.76 -1.85
Cytoplasm 0.84 3.75 -3.48 -9.65 -15.77 -10.59 -21.36 -21.33 -9.03 -2.84 -10.14 -18.93 -24.79 -13.14 -4.88
Cytoplasmic Foci 2.27 3.86 1.10 -4.41 -12.41 -1.63 1.85 -10.57 -7.83 -12.44 -2.15 3.48 -11.17 -8.71 -16.53
Eisosomes 0.55 2.94 -4.11 -4.81 -8.66 -0.84 -5.46 -6.52 -6.00 -0.86 -0.58 -5.02 -7.05 -7.63 -1.56
Endoplasmic Reticulum -6.61 -6.86 0.93 23.28 19.30 7.08 15.95 36.04 25.61 22.41 5.69 12.11 40.42 34.60 29.70
Endosome 1.73 1.85 -2.29 -6.21 -6.75 -1.94 -2.04 -14.88 -12.55 -13.95 -4.63 -2.05 -19.12 -13.29 -17.95
Golgi -0.91 1.96 -2.02 -2.07 -9.10 -3.17 1.17 -3.37 0.52 -6.12 -2.98 1.77 -4.16 -1.07 -8.20
Lipid Particles 1.41 1.90 -5.93 -12.16 -12.12 -6.98 -10.42 -19.96 -15.13 -12.95 -6.85 -9.82 -25.12 -19.39 -15.57
Mitochondria -0.79 1.41 -1.30 -0.94 -6.21 1.25 3.66 3.75 1.70 0.63 2.57 4.00 3.83 1.10 -0.08
Mitotic Spindle 1.63 1.71 -3.06 -5.93 -6.02 -1.40 0.20 -5.71 -4.53 -5.73 -0.70 1.53 -7.57 -7.30 -7.84
None -3.57 -1.74 -4.63 2.30 -2.34 1.83 -2.27 2.31 0.56 5.37 1.62 -2.02 2.83 1.90 6.10
Nuclear Periphery 0.07 -1.24 0.88 0.42 1.62 -0.66 2.51 -2.65 -2.52 -3.52 -1.18 0.29 -3.22 -1.08 -3.34
Nuclear Periphery Foci 1.93 -2.15 0.76 -4.06 4.70 -3.09 -1.15 -11.70 -9.66 -11.42 -4.26 -4.40 -13.23 -9.16 -9.27
Nucleolus -2.20 3.04 -6.05 -1.50 -9.61 -1.64 -3.82 -6.93 -4.43 -3.96 -2.47 -3.40 -8.60 -4.15 -4.98
Nucleus 1.77 2.39 -2.55 -10.26 -11.91 -7.01 -9.32 -14.61 -10.75 -7.25 -6.32 -8.40 -18.64 -14.84 -9.54
Peroxisomes -2.75 4.17 -5.99 -3.68 -9.31 5.84 2.53 3.11 -3.68 0.77 6.32 2.98 3.65 -5.11 0.74
Vacuole 6.99 6.04 3.79 -19.10 -9.92 -4.89 -7.90 -19.11 -16.86 -16.77 2.78 1.31 -18.97 -25.34 -23.93
Vacuole Periphery 1.24 1.49 1.21 -0.47 -4.94 0.37 4.32 0.68 0.14 -3.59 0.88 3.59 0.80 -0.19 -6.00
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mannosyltransferase; involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability; human homolog ALG1 complements yeast null mutant
Localization
Cell Percentages ER (99%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Alg1

Alg1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Alg1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available