Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – –
Cell Periphery 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 – – 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.16 – – 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 – – 0 0 0 0 0 0
Endosome 0 0 0 0 0.08 0 0.1 0.08 0 0 0 0 0 0.05 0 0 – – 0 0 0 0 0 0
Golgi 0 0 0.36 0.23 0.31 0 0.06 0 0 0 0 0 0.05 0.07 0.2 0.42 – – 0.05 0.1 0.05 0.05 0.09 0.09
Mitochondria 0.89 0.88 0.74 0.89 0.67 0.85 0.63 0.75 0.85 0.87 0.89 0.87 0.9 0.85 0.87 0.05 – – 0.8 0.76 0.84 0.76 0.69 0.67
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 – – 0 0 0 0 0 0
Nuclear Periphery 0.06 0.05 0.05 0 0.07 0.1 0.13 0.11 0.1 0.09 0.05 0.1 0.08 0 0 0.05 – – 0 0 0 0 0 0
Nucleolus 0.15 0 0 0 0 0.09 0.08 0.07 0.07 0.06 0.06 0.06 0 0 0 0 – – 0 0 0 0 0 0
Peroxisomes 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0.07 0 0.11 – – 0.05 0 0.06 0.09 0.07 0.07
SpindlePole 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0.14 0.09 0 0.11 0.08 0.13 0.1 0.07 0.05 0 0.05 0.06 0.1 0.08 0.05 – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 5 3 7 1 1 0 3 3 2 2 1 1 4 2 – – 1 6 3 5 14 18
Bud 2 2 2 3 4 6 8 10 10 16 10 9 2 3 3 1 – – 0 0 0 0 1 4
Bud Neck 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 1
Bud Site 1 0 0 0 0 1 0 0 0 2 3 6 0 0 0 0 – – – – – – – –
Cell Periphery 0 13 5 8 6 4 7 4 7 4 4 6 7 5 7 1 – – 0 0 0 0 0 1
Cytoplasm 3 7 3 6 8 12 18 19 11 4 9 8 1 10 17 3 – – 0 4 0 0 0 0
Endoplasmic Reticulum 0 4 4 0 2 2 2 2 1 6 1 4 2 2 3 1 – – 0 0 0 1 1 3
Endosome 2 2 6 13 31 12 67 53 14 26 5 27 3 19 11 0 – – 6 7 2 8 17 9
Golgi 1 6 77 76 118 4 40 13 4 9 5 16 13 29 86 8 – – 10 26 12 13 40 38
Mitochondria 170 220 157 293 256 360 414 483 458 517 434 602 237 351 378 1 – – 171 194 215 208 297 280
Nucleus 0 0 2 0 1 7 5 5 3 1 3 5 0 2 0 1 – – 0 0 0 0 0 0
Nuclear Periphery 11 13 10 8 27 41 83 69 52 54 26 67 22 15 18 1 – – 2 1 2 3 6 7
Nucleolus 28 5 4 8 13 37 53 46 38 36 31 40 9 12 8 0 – – 2 1 0 0 3 1
Peroxisomes 1 0 12 14 10 1 18 24 12 13 9 10 7 29 8 2 – – 11 5 15 24 29 31
SpindlePole 0 1 2 2 4 0 30 16 11 7 6 12 2 4 2 0 – – 2 0 0 1 3 1
Vac/Vac Membrane 14 35 20 13 44 33 83 67 37 28 15 34 17 40 34 1 – – 1 5 0 2 9 12
Unique Cell Count 191 249 213 328 383 423 654 646 537 595 486 694 262 411 435 19 214 257 257 276 431 416
Labelled Cell Count 234 309 309 447 531 522 829 811 661 726 563 848 323 522 579 22 214 257 257 276 431 416


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.1 9.8 10.2 9.7 10.1 7.1 8.7 8.3 7.8 7.6 7.6 7.5 10.0 10.2 9.9 9.6 – – 9.0 9.5 9.7
Std Deviation (1e-4) 1.8 1.8 1.5 1.6 1.7 1.7 1.7 1.6 1.6 1.7 1.6 1.6 1.7 1.5 1.7 1.4 – – 1.7 2.0 2.1
Intensity Change (Log2) – – – -0.07 -0.01 -0.52 -0.23 -0.29 -0.39 -0.43 -0.42 -0.44 -0.02 0.01 -0.03 -0.08 – – -0.17 -0.09 -0.07

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_10510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Cell Periphery 0.1 0 0 0 0 0 0 0 0 0.2 0 0 0 – –
Cytoplasm 0 0 1.1 1.1 1.2 0 0 0 0 0 0 1.7 0 – –
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Endosome 0.7 2.6 0 3.4 2.7 -0.2 1.0 0 0.7 0 1.1 -0.2 0 – –
Golgi -3.3 -1.3 -12.6 -11.1 -14.1 -14.1 -14.1 -13.3 -14.2 -8.6 -9.2 -4.5 0.5 – –
Mitochondria 4.7 -1.7 3.5 -2.8 0.3 3.7 4.4 5.2 4.5 4.8 3.6 4.2 -6.1 – –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Nuclear Periphery -1.4 1.1 2.2 3.3 2.6 2.2 2.0 0.4 2.3 1.6 -0.6 -0.3 0 – –
Nucleolus 0 1.1 3.3 3.2 2.8 2.8 2.4 2.5 2.3 1.0 0.8 0 0 – –
Peroxisomes -0.7 -1.9 0 -2.0 -1.2 -2.4 -2.5 -2.7 -3.5 -1.6 0.7 -2.6 0 – –
SpindlePole 0 0 0 2.5 0 0 0 0 0 0 0 0 0 – –
Vacuole -2.6 0.8 -0.7 1.3 0.4 -1.2 -2.5 -3.5 -2.4 -1.2 0.1 -0.7 0 – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.5878 4.9567 5.2731 4.1389 5.094 5.2175 8.4423 8.2998 7.8148 7.9628 9.0531 8.0804 8.2217 9.2481 8.0143 7.5617 8.021 8.2873
Actin 0.0156 0.0029 0.0123 0.0005 0.0042 0.0056 0.0589 0.0107 0.0252 0.0006 0.0295 0.0181 0.0145 0.0104 0.0242 0.0003 0.0041 0.0058
Bud 0.0002 0.0002 0.0013 0.0006 0.0002 0.0001 0.0009 0.0015 0.0003 0.0005 0.0027 0.0001 0.0005 0.0032 0.0006 0.0001 0.001 0.0004
Bud Neck 0.0006 0.0001 0.0002 0.0067 0 0.0001 0.0012 0.0005 0.0003 0.0001 0.0001 0.0001 0.0004 0.0001 0.0013 0 0.0001 0.0012
Bud Periphery 0.0003 0.0004 0.0034 0.0007 0.0004 0.0002 0.0014 0.002 0.0007 0.0023 0.0051 0.0003 0.001 0.0104 0.0011 0.0002 0.0014 0.0006
Bud Site 0.0003 0.001 0.0022 0.0097 0.0002 0.0001 0.0022 0.0039 0.0007 0.0002 0.0028 0.0001 0.0011 0.0023 0.0015 0 0.0006 0.0016
Cell Periphery 0.0002 0.0002 0.0005 0.0005 0 0.0002 0.0004 0.0005 0.0002 0.0005 0.0002 0.0001 0.0006 0.0005 0.0002 0 0.0001 0.0002
Cytoplasm 0.0028 0.0001 0.0007 0.0058 0 0.0006 0.0057 0.0004 0.0021 0.0002 0.0001 0.0001 0.0072 0.0001 0.0109 0 0.0003 0.0005
Cytoplasmic Foci 0.0065 0.0051 0.0029 0.0058 0.0023 0.0014 0.0058 0.0101 0.0044 0.0005 0.0047 0.0007 0.0237 0.003 0.0056 0.0001 0.0077 0.0095
Eisosomes 0.0003 0.0002 0.0003 0.0001 0.0001 0.0002 0.0008 0.0002 0.0003 0.0001 0.0002 0.0004 0.0005 0.0005 0.0004 0.0001 0.0001 0.0002
Endoplasmic Reticulum 0.0053 0.0002 0.0002 0.0004 0 0.0002 0.0048 0.0002 0.0017 0.0001 0.0001 0.0007 0.0036 0.0001 0.0002 0 0 0.0003
Endosome 0.0365 0.0168 0.0067 0.0172 0.0027 0.0056 0.0248 0.0268 0.0172 0.0161 0.0069 0.0124 0.0311 0.0193 0.0118 0.001 0.0076 0.0238
Golgi 0.0377 0.0358 0.0264 0.0051 0.0079 0.0146 0.0228 0.0364 0.0225 0.011 0.0276 0.018 0.0259 0.0141 0.021 0.002 0.0157 0.0398
Lipid Particles 0.0236 0.0177 0.0113 0.0014 0.0007 0.003 0.0341 0.0052 0.0219 0.0129 0.0015 0.0092 0.0624 0.042 0.0221 0.0015 0.0044 0.0184
Mitochondria 0.826 0.8962 0.9167 0.9287 0.9616 0.9524 0.7674 0.8641 0.8806 0.9394 0.9058 0.9195 0.6455 0.873 0.872 0.9926 0.9354 0.8826
None 0.0013 0.0001 0.0006 0.0001 0 0.0077 0.0067 0.0001 0.0018 0.0001 0.0001 0.0001 0.0147 0.0001 0.0001 0 0.0001 0.0001
Nuclear Periphery 0.0055 0.0002 0.001 0.0002 0 0.0001 0.0214 0.0002 0.0034 0.0001 0 0.0017 0.0671 0.0002 0.0001 0 0 0.0005
Nucleolus 0.0003 0.0012 0.0001 0.0005 0 0.0001 0.0017 0.004 0.0003 0.0001 0.0001 0.0001 0.0027 0.0002 0.0002 0 0.0001 0.0003
Nucleus 0.0016 0.0004 0.0001 0.0012 0 0.0001 0.0223 0.0005 0.0008 0.0001 0.0001 0.0002 0.0218 0.0002 0.0001 0 0 0.0005
Peroxisomes 0.0166 0.0121 0.0023 0.0032 0.019 0.006 0.004 0.0115 0.0041 0.0006 0.0067 0.0046 0.0403 0.012 0.0228 0.0007 0.0192 0.004
Punctate Nuclear 0.001 0 0 0.0002 0 0 0.0038 0.0002 0.0011 0 0.0001 0.0001 0.0161 0 0 0 0 0.0002
Vacuole 0.0097 0.0028 0.0021 0.0099 0.0002 0.0004 0.0036 0.0114 0.0022 0.0046 0.0016 0.0021 0.01 0.0033 0.0017 0.0002 0.0006 0.003
Vacuole Periphery 0.008 0.0063 0.0088 0.0018 0.0004 0.0014 0.0051 0.0097 0.0082 0.0101 0.004 0.0116 0.0096 0.005 0.002 0.0009 0.0013 0.0063

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.8288 33.2486 49.3438 40.4693 45.5438 35.1077 45.7574 47.2701 54.9421 48.0066
Translational Efficiency 2.1488 1.9893 1.2664 2.0335 1.1444 2.1953 1.5379 1.6904 1.6046 1.5978

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2103 1379 109 1774 1777 2499 1961 1640 3880 3878 2070 3414

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 813.26 1049.84 1510.41 1276.18 867.40 1060.01 1185.60 1316.23 838.06 1056.39 1202.70 1295.42
Standard Deviation 138.61 176.38 225.42 200.41 131.86 174.14 185.74 206.24 138.22 175.01 201.55 204.22
Intensity Change Log 2 — 0.368381 0.893152 0.650043 — 0.289309 0.450848 0.601642 — 0.328113 0.681798 0.625266

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002239 0.007204 0.009446 0.005399 0.001359 0.001792 0.001870 0.006544 0.001836 0.003716 0.002269 0.005949
Bud Neck 0.001841 0.001075 0.009471 0.002127 0.000871 0.000350 0.000985 0.000843 0.001397 0.000608 0.001431 0.001510
Bud Site 0.005496 0.002418 0.005269 0.008259 0.002939 0.000876 0.003136 0.003695 0.004325 0.001425 0.003248 0.006067
Cell Periphery 0.001463 0.000160 0.000191 0.000414 0.000127 0.000072 0.000150 0.000338 0.000851 0.000104 0.000152 0.000378
Cytoplasm 0.001143 0.000551 0.000785 0.000948 0.000312 0.000496 0.000426 0.000624 0.000762 0.000516 0.000445 0.000792
Cytoplasmic Foci 0.005122 0.017483 0.071480 0.010252 0.012297 0.006979 0.006607 0.009034 0.008408 0.010714 0.010023 0.009667
Eisosomes 0.000063 0.000188 0.000211 0.000157 0.000052 0.000082 0.000081 0.000145 0.000058 0.000120 0.000088 0.000151
Endoplasmic Reticulum 0.000316 0.000165 0.001197 0.000657 0.000117 0.000065 0.000074 0.000278 0.000225 0.000100 0.000133 0.000475
Endosome 0.007353 0.014229 0.031328 0.012078 0.015666 0.007803 0.006530 0.008253 0.011160 0.010088 0.007836 0.010241
Golgi 0.008241 0.038147 0.116040 0.044304 0.018036 0.015196 0.013722 0.054232 0.012727 0.023357 0.019110 0.049073
Lipid Particles 0.004887 0.006426 0.017420 0.004143 0.008579 0.002023 0.001111 0.001603 0.006578 0.003588 0.001970 0.002923
Mitochondria 0.941911 0.876264 0.595482 0.864681 0.912807 0.948255 0.947460 0.889808 0.928582 0.922655 0.928926 0.876752
Mitotic Spindle 0.001340 0.001501 0.056856 0.005936 0.001098 0.000749 0.002254 0.002273 0.001229 0.001017 0.005130 0.004176
None 0.001708 0.000403 0.001388 0.001071 0.000239 0.000295 0.000340 0.000533 0.001035 0.000334 0.000395 0.000813
Nuclear Periphery 0.000060 0.000122 0.006671 0.001692 0.000124 0.000039 0.000093 0.000189 0.000089 0.000069 0.000439 0.000970
Nuclear Periphery Foci 0.000109 0.000189 0.003348 0.001017 0.000299 0.000047 0.000080 0.000143 0.000196 0.000097 0.000252 0.000597
Nucleolus 0.000191 0.000150 0.000419 0.000227 0.000128 0.000030 0.000070 0.000044 0.000162 0.000072 0.000089 0.000139
Nucleus 0.000535 0.000052 0.000220 0.000201 0.000059 0.000103 0.000026 0.000025 0.000317 0.000085 0.000037 0.000116
Peroxisomes 0.012396 0.028748 0.026707 0.005273 0.019493 0.010949 0.010082 0.006037 0.015646 0.017278 0.010957 0.005640
Vacuole 0.001617 0.002211 0.016764 0.012016 0.002563 0.001840 0.002091 0.005820 0.002050 0.001972 0.002863 0.009040
Vacuole Periphery 0.001972 0.002312 0.029306 0.019147 0.002834 0.001959 0.002812 0.009538 0.002367 0.002084 0.004207 0.014531

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.10 -3.44 -3.15 1.26 1.81 -1.06 -1.22 -5.48 -5.16 -5.03 -3.57 -1.03 -5.92 -2.98 -5.39
Bud Neck 1.84 -3.35 -0.59 -2.88 3.23 2.73 -0.51 0.09 -2.70 0.62 3.35 -0.13 -0.42 -4.45 -0.32
Bud Site 2.48 0.10 -1.69 -3.89 -1.29 2.10 -0.19 -0.64 -3.49 -0.54 3.83 1.11 -1.70 -5.58 -2.79
Cell Periphery 3.67 3.59 2.92 -4.10 -3.55 2.76 -0.56 -3.08 -4.02 -2.51 3.88 3.58 2.39 -6.11 -4.05
Cytoplasm 2.07 1.22 0.07 -1.53 -0.90 -0.86 -1.44 -1.90 -0.47 -1.22 1.22 1.95 -0.42 -1.48 -2.05
Cytoplasmic Foci -8.11 -7.20 -5.04 4.42 6.63 4.23 4.49 2.45 -1.95 -2.25 -2.58 -1.58 -1.54 1.16 0.37
Eisosomes -7.70 -5.67 -4.78 1.59 1.92 -4.60 -3.20 -8.19 -5.15 -4.65 -7.28 -2.90 -7.95 -2.80 -4.99
Endoplasmic Reticulum 2.50 -3.07 -3.01 -4.97 1.79 3.11 2.77 -4.35 -5.72 -5.56 3.70 2.48 -4.00 -6.86 -6.03
Endosome -4.81 -5.34 -3.69 1.30 4.21 4.86 5.81 4.50 -0.40 -1.61 1.06 3.23 0.87 -0.18 -2.50
Golgi -10.16 -6.17 -11.27 -1.47 4.05 1.49 2.12 -9.11 -10.13 -10.35 -7.02 -3.45 -14.38 -9.52 -10.32
Lipid Particles -1.18 -2.48 0.66 2.11 2.65 5.46 6.49 5.77 0.74 -1.09 3.59 5.80 4.49 1.20 -1.99
Mitochondria 8.65 10.03 10.66 1.40 -7.70 -5.97 -5.63 3.03 8.96 8.59 1.31 -0.05 9.91 8.86 8.88
Mitotic Spindle -0.33 -3.51 -4.26 -4.07 3.21 1.37 -2.86 -2.45 -3.20 -0.02 0.85 -4.10 -4.84 -5.24 0.82
None 2.26 0.59 1.11 -7.19 1.62 -1.06 -4.51 -9.58 -4.09 -5.98 2.23 2.05 0.73 -8.02 -7.87
Nuclear Periphery -1.28 -1.96 -4.37 -4.18 1.47 3.33 1.10 -1.36 -3.69 -2.26 0.94 -1.94 -4.50 -4.60 -2.00
Nuclear Periphery Foci -1.27 -2.34 -2.67 -2.40 1.63 3.71 3.18 2.08 -2.93 -1.83 2.53 -0.69 -2.22 -2.80 -1.79
Nucleolus 0.61 -1.52 -0.39 -1.09 1.28 1.86 1.02 1.57 -1.58 1.26 2.06 1.59 0.43 -1.89 -1.31
Nucleus 2.57 1.64 0.82 -1.37 -0.51 -0.50 2.26 2.39 0.90 0.32 2.03 2.74 0.99 -0.82 -1.39
Peroxisomes -5.24 -1.65 4.20 8.14 2.50 3.63 4.03 6.05 3.12 2.68 -0.93 2.71 7.28 8.17 3.92
Vacuole -1.28 -4.57 -8.84 -8.40 1.36 1.40 0.97 -3.34 -4.21 -4.02 0.24 -2.05 -9.06 -9.26 -7.84
Vacuole Periphery -0.72 -4.73 -12.23 -12.19 1.71 1.99 0.05 -5.98 -6.85 -6.05 0.86 -3.63 -13.36 -13.85 -10.56
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region
Localization
Cell Percentages mitochondrion (98%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mrpl36

Mrpl36


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrpl36-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available