Standard name
Human Ortholog
Description Plasma membrane regulator of polyamine and carnitine transport; has similarity to transporters but lacks transport activity; may act as a sensor that transduces environmental signals; has a positive or negative regulatory effect on transcription of many transporter genes
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.07 0.05 0 0.05 0 0.14 0.16 0.15 0.16 0.19 0.14 0 0.11 0.2 0.2 – 0.21 0.08 0.11 0.18 0.09 0.08 0.09
Bud 0 0.06 0 0 0 0.05 0.07 0.08 0.08 0.09 0.08 0.06 0 0 0 0.08 – 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0.06 0.07 0.05 0.05 0.05 0.08
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 – – – – – –
Cell Periphery 0 0.14 0.13 0.09 0.13 0.13 0.23 0.2 0.23 0.21 0.21 0.16 0.12 0.15 0.22 0.25 – 0.16 0.09 0.18 0.21 0.21 0.25 0.24
Cytoplasm 0.93 0.91 0.89 0.88 0.74 0.72 0.57 0.55 0.57 0.53 0.5 0.55 0.89 0.74 0.58 0.51 – 0.63 0.44 0.36 0.16 0.32 0.28 0.2
Endoplasmic Reticulum 0 0 0 0 0.17 0.12 0.13 0.08 0.05 0.05 0.09 0.08 0 0.12 0.13 0.06 – 0 0.13 0.12 0.17 0.1 0.15 0.17
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0.11 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.07 0 0.15 0.18 0.18 0.27 0.28 0.31 0.26 0 0 0 0 – 0 0.07 0 0.12 0.12 0.06 0.08
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 – 0.05 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 – 0 0.06 0.05 0 0 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 11 16 14 5 14 9 56 73 47 64 56 47 48 131 205 13 – 4 22 26 52 39 58 61
Bud 6 15 9 6 6 11 28 34 26 34 25 21 11 33 37 5 – 1 2 4 1 11 20 28
Bud Neck 7 0 1 0 1 0 0 0 0 0 0 0 27 15 6 1 – 0 17 17 15 23 37 54
Bud Site 0 0 0 0 1 1 0 0 2 1 0 1 0 2 1 0 – 0 – – – – – –
Cell Periphery 12 34 37 25 36 32 92 88 73 83 61 52 137 175 231 16 – 3 25 46 61 91 173 166
Cytoplasm 247 219 247 237 209 173 233 245 178 211 148 179 1016 865 612 33 – 12 125 90 48 138 197 139
Endoplasmic Reticulum 6 1 7 7 47 29 52 35 15 21 26 26 48 138 136 4 – 0 38 30 50 45 107 115
Endosome 1 0 1 2 7 1 5 11 2 4 4 3 1 1 2 1 – 2 6 4 7 4 4 3
Golgi 3 1 0 0 0 0 0 0 0 1 0 0 0 0 1 0 – 0 1 3 0 1 0 3
Mitochondria 6 2 3 20 12 35 74 80 85 114 92 84 0 0 1 1 – 0 20 8 34 53 43 52
Nucleus 0 0 0 0 1 0 3 1 1 2 0 0 2 4 4 1 – 0 0 0 0 0 0 0
Nuclear Periphery 0 1 0 1 1 0 1 4 6 1 0 1 0 0 0 0 – 0 0 0 0 0 0 1
Nucleolus 0 0 0 0 0 0 0 1 1 0 1 0 0 0 0 0 – 0 0 0 0 0 0 0
Peroxisomes 0 0 4 2 8 3 17 17 5 7 3 3 0 1 1 0 – 0 1 0 0 0 0 1
SpindlePole 1 1 4 2 3 1 1 2 0 2 2 2 5 11 21 5 – 1 1 2 0 2 1 3
Vac/Vac Membrane 0 1 1 2 6 1 2 12 6 11 4 12 4 13 38 3 – 0 18 13 11 16 35 42
Unique Cell Count 267 241 278 268 284 241 407 446 314 400 297 327 1144 1176 1047 65 19 287 253 293 440 698 689
Labelled Cell Count 300 291 328 309 352 296 564 603 447 556 422 431 1299 1389 1296 83 23 287 253 293 440 698 689


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.6 5.4 4.7 5.2 6.1 5.8 6.1 7.0 6.7 6.6 7.1 7.2 6.3 7.3 8.2 8.4 – 11.6 5.8 6.3 6.6
Std Deviation (1e-4) 0.9 1.3 1.2 2.1 2.3 2.0 1.8 2.5 2.3 2.4 2.7 2.9 1.0 1.2 1.6 1.7 – 2.0 1.6 1.7 1.9
Intensity Change (Log2) – – – 0.14 0.38 0.31 0.37 0.58 0.52 0.5 0.6 0.62 0.43 0.63 0.8 0.84 – 1.31 0.31 0.42 0.48

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.0 -0.1 -0.7 3.7 4.6 4.0 4.4 5.1 3.8 -0.6 3.1 5.8 4.0 – 0
Bud -0.7 -0.8 0.8 2.1 2.4 2.6 2.8 2.6 1.8 0 -0.4 0.2 0 – 0
Bud Neck 0 0 0 0 0 0 0 0 0 2.2 0 0 0 – 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0
Cell Periphery -1.5 -0.2 0 3.1 2.2 3.1 2.5 2.3 0.9 -0.6 0.7 3.2 2.3 – 0
Cytoplasm -0.2 -4.6 -4.9 -8.9 -9.5 -8.7 -9.9 -10.1 -9.2 0 -5.4 -9.4 -7.1 – -3.2
Endoplasmic Reticulum 0.1 5.6 4.3 4.7 3.0 1.5 1.8 3.2 2.9 1.3 4.6 5.0 0 – 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0
Mitochondria 3.7 2.3 5.9 7.0 6.9 8.9 9.3 9.6 8.6 0 0 0 0 – 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0
Peroxisomes 0 1.1 0 2.0 1.9 0 0 0 0 0 0 0 0 – 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0.6 0 – 0
Vacuole 0 0 0 0 0 0 0 0 2.8 0 0 2.9 0 – 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.6575 5.0297 4.6472 4.546 4.414 4.5908 4.1977 5.7634 4.9089 5.1492 4.6255 5.3688 5.9623 7.5278 6.7301 6.8138 6.5609 5.9809
Actin 0.0594 0.0371 0.0496 0.0524 0.0843 0.0377 0.0505 0.0161 0.0273 0.0051 0.0102 0.0261 0.0693 0.0063 0.0347 0.0084 0.0072 0.0352
Bud 0.0042 0.0008 0.0012 0.001 0.003 0.001 0.0013 0.0003 0.0004 0.0007 0.0029 0.0006 0.0011 0.0004 0.0004 0.0007 0.0004 0.0007
Bud Neck 0.0072 0.0084 0.0154 0.0171 0.0188 0.0351 0.0067 0.0143 0.0449 0.0414 0.0375 0.0494 0.0076 0.007 0.0204 0.0391 0.0137 0.017
Bud Periphery 0.0127 0.0031 0.0133 0.0087 0.0182 0.0099 0.0076 0.0021 0.005 0.0082 0.0125 0.0078 0.0101 0.0033 0.0039 0.0094 0.0048 0.0116
Bud Site 0.0174 0.0656 0.0398 0.0059 0.0046 0.0052 0.0079 0.0581 0.0405 0.0087 0.1436 0.0029 0.0251 0.0656 0.022 0.0148 0.0044 0.0031
Cell Periphery 0.2012 0.236 0.25 0.262 0.2581 0.2236 0.3982 0.4319 0.3811 0.4379 0.1658 0.3482 0.301 0.4581 0.4382 0.5251 0.4873 0.4306
Cytoplasm 0.2564 0.4788 0.4388 0.3595 0.3943 0.4742 0.2657 0.293 0.3808 0.3688 0.5989 0.405 0.2971 0.3631 0.3392 0.346 0.3139 0.3706
Cytoplasmic Foci 0.0324 0.007 0.0135 0.0135 0.0148 0.0084 0.0056 0.0024 0.0033 0.0056 0.0024 0.0056 0.0048 0.0016 0.0033 0.0016 0.0019 0.0028
Eisosomes 0.0242 0.023 0.0108 0.0047 0.0107 0.0037 0.0202 0.0054 0.0115 0.0025 0.0014 0.0075 0.0802 0.0042 0.0257 0.0025 0.0031 0.0206
Endoplasmic Reticulum 0.0757 0.0663 0.0724 0.1529 0.0461 0.0928 0.067 0.0417 0.0232 0.0694 0.0094 0.0862 0.0853 0.0522 0.0531 0.0378 0.1119 0.0605
Endosome 0.047 0.0025 0.0175 0.0117 0.0388 0.015 0.0021 0.0023 0.0002 0.0006 0.0002 0.0035 0.0085 0.0003 0.0009 0.0002 0.0006 0.0014
Golgi 0.022 0.0105 0.0095 0.0183 0.0193 0.0084 0.0023 0.0039 0.0011 0.0018 0.0005 0.0034 0.0226 0.0017 0.0059 0.0007 0.0024 0.0029
Lipid Particles 0.0294 0.0219 0.0205 0.0274 0.0205 0.0206 0.0116 0.0374 0.0061 0.0225 0.0053 0.0135 0.0262 0.0246 0.0124 0.0054 0.0359 0.0174
Mitochondria 0.0076 0.0002 0.0026 0.0025 0.0092 0.0088 0.0006 0.0047 0 0.0001 0 0.0002 0.0038 0 0.0001 0 0 0.0005
None 0.0497 0.028 0.0313 0.0505 0.0248 0.0411 0.0958 0.0741 0.0684 0.0177 0.0036 0.0302 0.043 0.0019 0.0211 0.0013 0.0006 0.0172
Nuclear Periphery 0.0237 0.0015 0.0029 0.002 0.0177 0.0023 0.0025 0.0029 0.0008 0.0007 0.0004 0.0013 0.0064 0.0012 0.0011 0.0011 0.0013 0.0012
Nucleolus 0.0048 0.0004 0.0002 0.0005 0.0004 0.0006 0.0004 0.0002 0.0002 0.0002 0.0004 0.0002 0.0004 0.0002 0.0001 0.0001 0.0001 0.0001
Nucleus 0.0662 0.0007 0.0006 0.0009 0.0023 0.0017 0.0017 0.0004 0.0004 0.0005 0.0006 0.0004 0.0009 0.0004 0.0004 0.0003 0.0002 0.0003
Peroxisomes 0.0213 0.0002 0.0031 0.0009 0.0037 0.0009 0.0008 0.0015 0.0002 0 0.0001 0.0014 0.0009 0 0.0001 0 0 0.0003
Punctate Nuclear 0.0105 0.0004 0.0011 0.0017 0.0032 0.0014 0.0002 0.0005 0.0002 0.0002 0.0006 0.0019 0.0012 0.0001 0.0001 0.0001 0.0001 0.0002
Vacuole 0.0234 0.0074 0.0054 0.0056 0.005 0.0074 0.0351 0.0067 0.0044 0.0073 0.0037 0.0048 0.0038 0.0076 0.0159 0.0054 0.0102 0.0058
Vacuole Periphery 0.0036 0.0001 0.0005 0.0003 0.0022 0.0005 0.0166 0.0003 0 0.0001 0 0.0001 0.0007 0 0.0011 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 21.8709 18.1744 17.5729 22.3059 9.186 51.1066 37.5876 38.7113 44.5339 28.4633
Translational Efficiency 0.6038 0.6621 0.6139 0.9142 0.9085 0.6782 0.8014 0.8189 0.7804 0.6565

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
134 1276 292 1214 1834 1858 127 1185 1968 3134 419 2399

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1236.26 750.28 1534.36 1098.45 744.08 858.60 1222.27 972.82 777.59 814.50 1439.76 1036.39
Standard Deviation 307.32 132.18 274.33 202.86 127.05 139.77 238.15 192.23 191.95 146.72 300.35 207.42
Intensity Change Log 2 — -0.720481 0.311655 -0.170513 — 0.206528 0.716033 0.386715 — -0.299691 0.477157 0.064767

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000904 0.074244 0.015551 0.034183 0.023064 0.033810 0.022042 0.021919 0.021555 0.050272 0.017518 0.028125
Bud Neck 0.012922 0.043054 0.019694 0.041262 0.043784 0.067902 0.017658 0.041716 0.041683 0.057785 0.019077 0.041487
Bud Site 0.036172 0.057750 0.035718 0.086183 0.027477 0.043779 0.027995 0.077101 0.028069 0.049467 0.033377 0.081697
Cell Periphery 0.003394 0.048398 0.278776 0.181559 0.027569 0.109401 0.155096 0.067902 0.025923 0.084563 0.241289 0.125417
Cytoplasm 0.039110 0.305228 0.028874 0.175029 0.495584 0.451228 0.120395 0.272525 0.464503 0.391784 0.056614 0.223188
Cytoplasmic Foci 0.017695 0.122869 0.005133 0.008596 0.109720 0.053987 0.032778 0.031803 0.103454 0.082032 0.013512 0.020059
Eisosomes 0.000197 0.049663 0.006211 0.014778 0.042207 0.078313 0.014054 0.010402 0.039346 0.066648 0.008588 0.012616
Endoplasmic Reticulum 0.004995 0.035105 0.326035 0.095392 0.015105 0.016128 0.264709 0.041587 0.014416 0.023854 0.307447 0.068815
Endosome 0.045319 0.028703 0.016122 0.008871 0.008133 0.006871 0.015846 0.018148 0.010665 0.015760 0.016038 0.013453
Golgi 0.013129 0.046837 0.008765 0.002848 0.016266 0.014694 0.011007 0.005462 0.016052 0.027781 0.009444 0.004139
Lipid Particles 0.001782 0.058819 0.110505 0.031051 0.024996 0.018180 0.063527 0.017615 0.023415 0.034726 0.096266 0.024414
Mitochondria 0.001963 0.010226 0.000114 0.001756 0.005295 0.005493 0.000104 0.002244 0.005068 0.007420 0.000111 0.001997
Mitotic Spindle 0.021313 0.000242 0.000541 0.000968 0.000647 0.000354 0.000132 0.003122 0.002054 0.000308 0.000417 0.002032
None 0.000219 0.001592 0.000029 0.000247 0.002169 0.000742 0.000044 0.000187 0.002036 0.001088 0.000034 0.000217
Nuclear Periphery 0.001448 0.000245 0.001442 0.000285 0.000265 0.000155 0.000477 0.000198 0.000346 0.000192 0.001149 0.000242
Nuclear Periphery Foci 0.001157 0.001587 0.007092 0.003580 0.000564 0.000499 0.007827 0.003089 0.000604 0.000942 0.007315 0.003338
Nucleolus 0.001429 0.000649 0.000021 0.000116 0.000322 0.000211 0.000048 0.000140 0.000397 0.000389 0.000029 0.000128
Nucleus 0.029670 0.032973 0.000796 0.009582 0.102457 0.046084 0.012234 0.022358 0.097501 0.040746 0.004263 0.015892
Peroxisomes 0.002249 0.046785 0.001831 0.003102 0.018268 0.019604 0.004949 0.002952 0.017177 0.030671 0.002776 0.003028
Vacuole 0.687580 0.033392 0.133433 0.299181 0.035603 0.032060 0.228468 0.357522 0.079996 0.032602 0.162238 0.327999
Vacuole Periphery 0.077353 0.001638 0.003316 0.001432 0.000505 0.000505 0.000610 0.002007 0.005737 0.000966 0.002496 0.001716

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -16.94 -4.56 -12.39 8.12 -4.36 -3.76 0.28 0.87 4.64 0.24 -10.04 1.27 -2.25 8.54 -3.16
Bud Neck -6.99 -1.46 -6.56 0.85 -6.60 -7.11 7.31 1.34 7.68 -5.70 -6.00 8.73 0.74 7.10 -8.57
Bud Site -1.82 0.34 -4.60 -5.23 -7.09 -5.44 -0.16 -10.57 -6.47 -5.58 -7.98 -1.21 -14.91 -8.64 -8.72
Cell Periphery -10.66 -17.12 -26.46 -17.72 6.00 -15.91 -6.13 -7.75 7.42 4.31 -15.76 -16.33 -21.81 -6.93 8.85
Cytoplasm -21.44 1.01 -11.75 14.47 -18.62 5.29 24.49 23.75 18.60 -9.86 9.57 47.30 31.48 25.00 -21.94
Cytoplasmic Foci -16.49 2.56 1.83 25.32 -2.40 13.60 10.26 20.12 7.35 0.27 5.41 22.76 24.55 24.08 -2.61
Eisosomes -17.35 -4.92 -12.44 11.51 -4.92 -9.82 8.79 13.25 22.55 1.64 -9.15 12.83 12.10 24.66 -2.69
Endoplasmic Reticulum -10.17 -17.47 -17.68 -10.26 12.29 -0.49 -9.54 -7.05 -6.74 8.56 -4.70 -19.33 -15.93 -12.91 15.67
Endosome 2.18 3.86 5.02 10.04 3.74 1.66 -3.68 -6.42 -7.44 -0.50 -4.56 -3.37 -2.18 2.59 2.00
Golgi -6.17 0.79 2.02 16.99 5.39 1.20 1.94 7.67 7.16 1.99 -7.65 4.58 10.65 18.17 4.49
Lipid Particles -16.62 -10.69 -14.24 7.37 7.77 3.51 -2.93 4.23 1.02 3.60 -5.25 -8.79 -0.03 5.82 8.84
Mitochondria -5.21 1.54 0.15 6.50 -2.16 -0.24 9.19 3.29 3.26 -2.46 -2.94 9.34 4.19 6.84 -3.27
Mitotic Spindle 1.91 1.88 1.84 -1.52 -0.78 0.94 1.57 -1.94 -2.39 -2.62 2.18 2.04 0.16 -2.76 -2.57
None -2.78 2.53 -0.02 2.72 -1.58 4.31 7.22 6.70 3.42 -3.79 2.64 7.31 6.44 3.81 -2.60
Nuclear Periphery 1.54 0.28 1.51 -0.64 6.64 2.01 -2.64 1.01 -2.39 4.46 2.03 -5.28 1.41 -2.05 7.28
Nuclear Periphery Foci -0.60 -6.14 -5.00 -4.13 4.08 1.19 -7.78 -10.65 -11.16 5.08 -1.91 -10.05 -16.49 -10.18 6.01
Nucleolus 1.71 4.07 3.81 1.55 -8.53 2.12 6.54 4.40 1.61 -4.65 0.18 8.20 6.06 1.84 -9.59
Nucleus 0.02 2.80 1.93 9.77 -12.66 15.74 18.82 22.56 8.92 -3.10 17.08 28.97 25.49 14.06 -9.50
Peroxisomes -16.65 0.28 -0.58 18.50 -2.03 -0.81 7.85 12.91 14.01 1.63 -8.27 12.04 12.70 22.69 -0.29
Vacuole 24.51 19.25 13.60 -35.80 -13.46 1.74 -9.35 -40.24 -40.64 -5.61 10.55 -7.94 -36.91 -53.93 -14.90
Vacuole Periphery 6.64 6.45 6.66 0.70 1.47 -0.01 -0.29 -3.83 -3.80 -2.38 5.32 2.50 4.45 -2.75 0.94
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Plasma membrane regulator of polyamine and carnitine transport; has similarity to transporters but lacks transport activity; may act as a sensor that transduces environmental signals; has a positive or negative regulatory effect on transcription of many transporter genes
Localization
Cell Percentages ER (9%), cytoplasm (7%), mixed (47%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Agp2

Agp2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Agp2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available