Standard name
Human Ortholog
Description Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; role in membrane organization at trans-Golgi network; required for delivery of Atg9p to the phagophore assembly site during autophagy under high temperature stress; required with Ypt6p for starvation-induced autophagy; required for the CVT pathway under non-starvation conditions; G protein of the Ras superfamily, similar to ADP-ribosylation factor
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.25 0.28 0.19 0.09 0.15 0.21 0.05 0.11 – 0.12 0.07 0.15 0.36 0.15 0.11 0.12 – 0.12 0.06 0.1 0.07 0.06 0 0.06
Bud 0 0 0.08 0 0.05 0 0.05 0.08 – 0 0.06 0.07 0 0 0 0.12 – 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Cytoplasm 0 0.13 0.06 0.12 0.09 0.09 0.06 0.14 – 0.12 0.21 0.18 0.06 0 0 0.18 – 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.11 0 0 0 0.08 0.06 0.07 – 0.06 0.06 0.1 0.13 0 0 0 – 0 0 0 0 0 0 0
Endosome 0.09 0 0.24 0.19 0.22 0.16 0.1 0.08 – 0.17 0.06 0.08 0.06 0.12 0.07 0.06 – 0 0.24 0.18 0.23 0.29 0.25 0.21
Golgi 0.75 0.64 0.35 0.38 0.36 0.24 0.1 0.07 – 0.14 0.07 0.12 0.67 0.75 0.8 0.76 – 0.81 0.6 0.56 0.6 0.56 0.59 0.64
Mitochondria 0.11 0.07 0.53 0.5 0.44 0.63 0.74 0.6 – 0.52 0.61 0.55 0 0.05 0.06 0.24 – 0.12 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0 0.05 0 0 – 0 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0.05 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0.08 0 0 0 0 0 0.06 – 0.07 0.06 0 0.09 0.15 0.11 0 – 0.19 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 80 86 18 15 28 35 16 31 – 29 14 40 73 51 53 2 – 2 21 35 7 11 7 19
Bud 5 4 8 4 10 7 18 22 – 6 12 17 7 2 3 2 – 0 1 5 0 0 3 1
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 2 1 – 3 0 4 0 0 0 0 – 0 – – – – – –
Cell Periphery 1 4 0 1 0 0 3 3 – 2 4 0 1 1 3 0 – 0 0 0 0 0 0 0
Cytoplasm 14 39 6 21 16 15 19 40 – 31 43 46 13 8 21 3 – 0 1 7 0 0 1 4
Endoplasmic Reticulum 14 32 3 3 5 14 19 19 – 15 13 25 27 15 5 0 – 0 1 3 0 0 2 2
Endosome 28 12 23 32 41 26 35 23 – 43 13 22 12 41 32 1 – 0 90 63 24 55 63 72
Golgi 244 194 34 66 67 39 32 20 – 35 15 30 137 253 374 13 – 13 227 191 64 108 148 222
Mitochondria 36 21 51 86 82 104 248 166 – 131 127 144 9 16 28 4 – 2 2 6 1 2 6 5
Nucleus 0 0 0 0 0 0 0 1 – 0 0 1 1 1 1 0 – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 1 1 0 1 0 – 2 3 0 0 0 2 0 – 0 0 0 0 0 0 0
Nucleolus 16 10 2 3 7 8 10 11 – 8 6 13 2 8 11 0 – 0 0 0 1 0 0 0
Peroxisomes 0 0 0 2 1 0 5 3 – 1 0 2 0 2 0 0 – 0 16 12 2 9 6 8
SpindlePole 7 1 1 4 6 2 9 2 – 9 0 3 0 6 14 0 – 0 6 2 1 1 3 2
Vac/Vac Membrane 32 24 2 6 8 5 15 16 – 18 12 9 18 51 52 0 – 3 4 11 0 1 2 6
Unique Cell Count 326 304 97 172 188 165 336 277 251 207 260 204 337 470 17 16 378 343 108 192 251 349
Labelled Cell Count 477 427 148 244 272 255 432 358 333 262 356 300 455 599 25 20 378 343 108 192 251 349


Early Golgi, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 15.2 16.2 10.2 10.1 9.5 8.9 8.0 8.6 – 8.5 8.1 8.6 14.8 15.5 15.5 20.2 – 21.7 16.5 16.1 16.6
Std Deviation (1e-4) 2.3 2.6 2.1 2.0 1.8 1.6 1.6 1.8 – 1.7 1.7 1.7 2.3 2.6 2.7 4.7 – 5.2 2.2 3.0 2.6
Intensity Change (Log2) – – – -0.01 -0.11 -0.2 -0.36 -0.24 – -0.26 -0.34 -0.24 0.53 0.6 0.61 0.98 – 1.09 0.69 0.66 0.7


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.4 -0.8 0.5 -4.4 -1.9 – -1.7 -3.1 -0.7 3.0 -0.8 -2.0 0 – 0
Bud 0 -1.0 -1.3 -1.1 -0.1 – 0 -0.8 -0.6 0 0 0 0 – 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0
Cytoplasm 1.6 0.7 0.8 -0.2 2.1 – 1.7 3.2 2.7 0.1 0 0 0 – 0
Endoplasmic Reticulum 0 0 1.7 0 1.4 – 1.1 1.2 2.0 2.7 0 0 0 – 0
Endosome -1.0 -0.4 -1.6 -3.4 -4.0 – -1.4 -4.4 -3.9 -4.5 -2.8 -5.1 0 – 0
Golgi 0.5 0.1 -2.0 -6.2 -6.7 – -4.4 -6.1 -5.2 5.3 7.3 8.9 3.2 – 3.5
Mitochondria -0.4 -1.4 1.7 4.0 1.3 – -0.1 1.4 0.5 -9.8 -11.5 -12.1 -2.2 – -3.0
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 – 0
Vacuole 0 0 0 0 0 – 1.8 0 0 2.2 3.5 2.7 0 – 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 12.3672 13.4394 12.3456 12.4234 12.6478 13.079 13.5114 15.2595 14.1098 13.1882 13.7005 15.1719 12.1538 14.7669 12.7123 13.112 11.3759 14.1345
Actin 0.0188 0.0112 0.0396 0.0482 0.0049 0.0182 0.0747 0.0378 0.0338 0.0505 0.0009 0.0258 0.041 0.0138 0.0107 0.0033 0.0063 0.0109
Bud 0.0002 0.0001 0.0003 0.0003 0.0001 0.0001 0.0003 0.0006 0.0002 0.0001 0 0.0001 0.0003 0.0002 0.0003 0.0001 0.0001 0.0001
Bud Neck 0.0004 0.0004 0.0009 0.0003 0.0002 0.0005 0.0009 0.0003 0.0004 0.0004 0.0001 0.0004 0.0006 0.0004 0.0019 0.0002 0.0002 0.0003
Bud Periphery 0.0001 0.0001 0.0001 0.0002 0 0.0001 0.0003 0.0003 0.0002 0.0001 0 0.0001 0.0003 0.0001 0.0004 0 0.0001 0
Bud Site 0.0004 0.0004 0.0006 0.0004 0.0001 0.0001 0.0014 0.0048 0.001 0.0004 0.0001 0.0001 0.0011 0.0013 0.0029 0.0001 0.0011 0.0001
Cell Periphery 0.0001 0.0001 0 0.0001 0 0 0.0002 0 0.0001 0 0 0 0.0001 0 0.0001 0 0.0001 0
Cytoplasm 0.006 0.0034 0.0062 0.0026 0.0019 0.0036 0.0239 0.0032 0.0127 0.0292 0.0017 0.0121 0.0037 0.0085 0.0022 0.0042 0.0027 0.0023
Cytoplasmic Foci 0.1329 0.1786 0.1485 0.099 0.1414 0.0812 0.1199 0.1613 0.1088 0.1538 0.1455 0.1072 0.1145 0.1529 0.1031 0.091 0.1151 0.0738
Eisosomes 0.0001 0 0 0.0001 0 0 0.0003 0.0001 0.0001 0 0 0 0.0003 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0014 0.0003 0.0005 0.0015 0.0003 0.0006 0.003 0.0003 0.001 0.0013 0.0004 0.0014 0.0011 0.0006 0.0005 0.0004 0.0016 0.0004
Endosome 0.1957 0.1751 0.1603 0.1414 0.1429 0.1363 0.1403 0.1197 0.1516 0.212 0.1953 0.0959 0.1888 0.1851 0.1734 0.253 0.2204 0.1161
Golgi 0.6033 0.5858 0.6024 0.6469 0.6937 0.742 0.5272 0.6231 0.6596 0.5182 0.6224 0.6945 0.5749 0.617 0.6668 0.6068 0.6127 0.7598
Lipid Particles 0.0132 0.0202 0.0191 0.0426 0.0091 0.0079 0.0552 0.0099 0.0079 0.0189 0.0186 0.0274 0.0296 0.0045 0.014 0.0239 0.0215 0.025
Mitochondria 0.0104 0.0036 0.0031 0.0031 0.0013 0.0026 0.0052 0.0034 0.0019 0.0021 0.0009 0.0029 0.0153 0.0023 0.0034 0.0036 0.0035 0.002
None 0.0006 0 0.0001 0.0002 0.0004 0 0.0019 0.0003 0.0011 0.0003 0.0001 0.0002 0.0018 0 0.0008 0 0.0006 0
Nuclear Periphery 0.0021 0.0001 0.0001 0.0003 0.0001 0.0002 0.0056 0.0005 0.0019 0.0002 0.0002 0.0046 0.0017 0.0002 0.0004 0.0001 0.0011 0.0001
Nucleolus 0 0.0001 0 0 0.0001 0 0.0003 0.0001 0.0001 0 0.0001 0 0.0018 0 0.0001 0.0001 0.0001 0
Nucleus 0.0002 0.0001 0 0 0.0001 0 0.0008 0.0001 0.0023 0.0001 0 0.0001 0.001 0.0001 0.0002 0 0.0002 0
Peroxisomes 0.0101 0.0176 0.0166 0.0107 0.0016 0.0046 0.0283 0.0327 0.011 0.0103 0.009 0.0247 0.0147 0.0105 0.0154 0.0098 0.0077 0.007
Punctate Nuclear 0.0003 0.0006 0.0004 0.0003 0.0007 0.0001 0.0079 0.0007 0.0013 0.0003 0.0034 0.0012 0.0037 0.0002 0.0017 0.0001 0.0008 0.0001
Vacuole 0.0017 0.0011 0.0005 0.0006 0.0004 0.0008 0.0013 0.0004 0.0018 0.0009 0.0005 0.0004 0.0019 0.0014 0.0008 0.0014 0.0019 0.0008
Vacuole Periphery 0.002 0.0011 0.0007 0.0011 0.0006 0.001 0.0012 0.0005 0.0014 0.0008 0.0007 0.001 0.0017 0.0007 0.001 0.0018 0.0019 0.0012

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 53.9709 50.0336 72.9282 84.3154 62.2005 45.9497 74.0766 64.0202 76.384 72.903
Translational Efficiency 2.5082 2.7176 1.9278 1.5111 1.9821 2.7959 2.0209 2.3148 1.8128 1.7899

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
206 1333 2047 108 1482 1953 2638 896 1688 3286 4685 1004

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 999.74 1296.28 1722.13 1840.58 1014.96 1319.11 1767.74 1592.33 1013.10 1309.85 1747.81 1619.03
Standard Deviation 190.96 234.37 310.95 422.90 222.15 252.72 400.92 343.33 218.64 245.70 365.05 361.04
Intensity Change Log 2 — 0.374753 0.784569 0.880536 — 0.378142 0.800483 0.649716 — 0.376461 0.792608 0.768867

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.013287 0.019953 0.007991 0.057375 0.008872 0.012124 0.014431 0.024101 0.009410 0.015300 0.011617 0.027681
Bud Neck 0.005329 0.000675 0.001960 0.008226 0.001557 0.000532 0.001182 0.002753 0.002017 0.000590 0.001522 0.003341
Bud Site 0.010410 0.003345 0.004920 0.049886 0.006008 0.004432 0.008259 0.032286 0.006546 0.003991 0.006800 0.034180
Cell Periphery 0.000228 0.000106 0.000124 0.000370 0.000244 0.000056 0.000153 0.000266 0.000243 0.000076 0.000140 0.000277
Cytoplasm 0.004150 0.002307 0.001974 0.005384 0.005474 0.004486 0.004761 0.017335 0.005313 0.003602 0.003543 0.016050
Cytoplasmic Foci 0.288942* 0.320449* 0.201963* 0.222758* 0.254649* 0.333567* 0.166182 0.243448* 0.258834* 0.328245* 0.181816* 0.241223*
Eisosomes 0.000130 0.000086 0.000047 0.000117 0.000094 0.000049 0.000075 0.000078 0.000098 0.000064 0.000063 0.000082
Endoplasmic Reticulum 0.001966 0.000901 0.001174 0.003204 0.001355 0.000438 0.000531 0.002444 0.001429 0.000626 0.000812 0.002525
Endosome 0.150923 0.147647 0.163360 0.182078 0.182716 0.162378 0.212420* 0.172104 0.178836 0.156403 0.190984 0.173177
Golgi 0.402279* 0.436922* 0.451983* 0.251934* 0.420724* 0.430401* 0.477962* 0.357009* 0.418473* 0.433046* 0.466612* 0.345706*
Lipid Particles 0.023964 0.042486 0.078493 0.062533 0.054185 0.015735 0.047999 0.046745 0.050497 0.026587 0.061323 0.048443
Mitochondria 0.041430 0.004638 0.003633 0.000454 0.025061 0.006419 0.009719 0.002407 0.027058 0.005696 0.007060 0.002197
Mitotic Spindle 0.016481 0.004098 0.026820 0.054966 0.004735 0.011628 0.022993 0.053517 0.006168 0.008574 0.024665 0.053673
None 0.000103 0.000044 0.000040 0.000031 0.000256 0.000023 0.000063 0.000051 0.000237 0.000032 0.000053 0.000049
Nuclear Periphery 0.000085 0.000067 0.001249 0.001011 0.000092 0.000042 0.000350 0.000256 0.000092 0.000052 0.000743 0.000338
Nuclear Periphery Foci 0.000941 0.001141 0.006733 0.021439 0.004575 0.000521 0.001648 0.006536 0.004132 0.000772 0.003870 0.008139
Nucleolus 0.000184 0.000031 0.000061 0.000031 0.000869 0.000031 0.000026 0.000020 0.000786 0.000031 0.000042 0.000021
Nucleus 0.003824 0.000052 0.000059 0.000117 0.000654 0.000044 0.000067 0.000186 0.001041 0.000047 0.000063 0.000178
Peroxisomes 0.021895 0.007479 0.002683 0.009251 0.015107 0.009270 0.004757 0.003485 0.015935 0.008544 0.003851 0.004106
Vacuole 0.008660 0.005411 0.034185 0.064669 0.008645 0.005649 0.019357 0.030115 0.008646 0.005552 0.025836 0.033831
Vacuole Periphery 0.004788 0.002163 0.010549 0.004167 0.004128 0.002175 0.007064 0.004857 0.004209 0.002170 0.008587 0.004783

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.50 1.30 -2.69 -2.32 -3.11 -1.88 -3.42 -5.34 -4.06 -3.31 -3.72 -1.67 -5.89 -3.95 -5.26
Bud Neck 1.50 1.06 -1.03 -6.72 -5.57 4.73 1.41 -4.03 -9.08 -5.98 3.40 1.06 -3.03 -10.82 -6.93
Bud Site 3.32 2.43 -4.24 -5.03 -4.85 1.80 -2.58 -10.32 -11.14 -9.36 3.33 -0.72 -11.11 -12.39 -11.09
Cell Periphery 3.16 2.81 -2.57 -5.83 -5.63 3.72 1.70 -0.69 -11.48 -5.45 3.68 2.20 -1.02 -11.37 -7.65
Cytoplasm 1.52 1.57 -0.86 -2.50 -2.56 0.78 0.39 -6.09 -6.61 -6.59 1.78 1.68 -6.15 -7.29 -7.30
Cytoplasmic Foci -2.31 6.50 2.87 4.99 -1.13 -13.49 17.90 1.79 12.46 -11.30 -13.72 16.97 2.75 13.40 -9.31
Eisosomes 2.58 5.01 0.60 -1.47 -3.52 6.50 2.55 1.91 -5.30 -0.49 5.26 5.53 2.06 -3.31 -3.61
Endoplasmic Reticulum 2.40 1.74 -0.91 -1.74 -1.53 5.43 4.86 -3.19 -6.50 -6.20 5.10 3.77 -3.23 -6.13 -5.48
Endosome 0.30 -1.19 -1.85 -2.51 -1.31 3.92 -5.50 2.03 -1.54 7.59 4.99 -2.60 1.29 -3.23 4.01
Golgi -2.10 -2.83 5.36 7.50 7.96 -1.21 -6.90 6.53 7.71 11.99 -2.14 -6.61 7.81 10.00 13.19
Lipid Particles -2.85 -8.23 -2.89 -1.60 1.25 9.84 1.36 1.40 -9.04 0.20 6.55 -2.79 0.33 -6.36 3.27
Mitochondria 5.02 5.17 5.62 5.76 4.78 7.95 6.46 9.94 3.65 6.31 9.74 9.10 11.33 4.16 5.72
Mitotic Spindle 2.95 -2.16 -2.96 -4.16 -2.23 -4.27 -9.51 -10.27 -8.52 -5.90 -1.96 -11.52 -10.63 -10.02 -6.17
None 2.51 2.99 3.39 0.99 1.42 4.29 3.49 3.69 -4.92 0.75 4.30 3.84 3.87 -2.80 0.16
Nuclear Periphery 1.39 -9.11 -2.27 -2.32 0.56 5.29 -9.06 -5.98 -8.06 2.27 4.62 -11.18 -4.97 -5.80 5.18
Nuclear Periphery Foci -0.05 -6.18 -2.60 -2.60 -1.85 3.70 2.61 -1.39 -5.04 -4.09 3.49 0.07 -2.55 -5.42 -3.03
Nucleolus 1.14 0.89 1.12 -0.20 2.36 3.18 3.35 3.38 0.86 1.09 3.34 3.35 3.47 0.94 3.16
Nucleus 1.11 1.10 1.09 -1.53 -1.21 2.46 2.39 1.63 -2.81 -2.42 2.11 2.08 1.72 -2.98 -2.66
Peroxisomes 3.45 4.68 2.92 -1.00 -4.27 3.67 7.36 8.49 6.82 2.31 5.20 9.25 9.01 6.52 -0.42
Vacuole 1.85 -11.05 -5.50 -5.89 -3.06 3.62 -9.70 -10.56 -12.11 -5.29 4.41 -16.38 -11.79 -13.44 -4.01
Vacuole Periphery 2.44 -4.90 0.53 -2.72 7.44 6.14 -7.55 -1.47 -5.75 4.25 6.99 -11.51 -1.23 -6.35 7.92
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; role in membrane organization at trans-Golgi network; required for delivery of Atg9p to the phagophore assembly site during autophagy under high temperature stress; required with Ypt6p for starvation-induced autophagy; required for the CVT pathway under non-starvation conditions; G protein of the Ras superfamily, similar to ADP-ribosylation factor
Localization
Cell Percentages Golgi (11%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Arl1

Arl1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Arl1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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